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Items: 32

1.

UC-Genentech trial.

Henner D, Goeddel DV, Heyneker H, Itakura K, Tansura D.

Science. 1999 May 28;284(5419):1465. No abstract available.

PMID:
10383322
2.

Genentech stands by original data.

Henner DJ, Goeddel DV, Heyneker H, Itakura K, Yansura D, Ross M, Miozzari G.

Nature. 1999 May 27;399(6734):297-8. No abstract available.

PMID:
10360564
3.

Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides.

Stemmer WP, Crameri A, Ha KD, Brennan TM, Heyneker HL.

Gene. 1995 Oct 16;164(1):49-53.

PMID:
7590320
4.

Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. 1977.

Itakura K, Tadaaki H, Crea R, Riggs AD, Heyneker HL, Bolivar F, Boyer HW.

Biotechnology. 1992;24:84-91. No abstract available.

PMID:
1358295
5.

Functional role of proteolytic cleavage at arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis.

Tate KM, Higgins DL, Holmes WE, Winkler ME, Heyneker HL, Vehar GA.

Biochemistry. 1987 Jan 27;26(2):338-43.

PMID:
3103680
6.

High-level secretion of human growth hormone by Escherichia coli.

Chang CN, Rey M, Bochner B, Heyneker H, Gray G.

Gene. 1987;55(2-3):189-96.

PMID:
3311882
7.
8.

Non-toxic expression in Escherichia coli of a plasmid-encoded gene for phage T4 lysozyme.

Perry LJ, Heyneker HL, Wetzel R.

Gene. 1985;38(1-3):259-64.

PMID:
3905515
9.

Generation of antibody activity from immunoglobulin polypeptide chains produced in Escherichia coli.

Cabilly S, Riggs AD, Pande H, Shively JE, Holmes WE, Rey M, Perry LJ, Wetzel R, Heyneker HL.

Proc Natl Acad Sci U S A. 1984 Jun;81(11):3273-7.

10.

Cloning, nucleotide sequence, and expression in Escherichia coli of the exotoxin A structural gene of Pseudomonas aeruginosa.

Gray GL, Smith DH, Baldridge JS, Harkins RN, Vasil ML, Chen EY, Heyneker HL.

Proc Natl Acad Sci U S A. 1984 May;81(9):2645-9.

11.

Complete nucleotide sequence of the glutamate dehydrogenase gene from Escherichia coli K-12.

Valle F, Becerril B, Chen E, Seeburg P, Heyneker H, Bolivar F.

Gene. 1984 Feb;27(2):193-9.

PMID:
6373501
12.

Nucleotide sequence of the gene for heat-stable enterotoxin II of Escherichia coli.

Picken RN, Mazaitis AJ, Maas WK, Rey M, Heyneker H.

Infect Immun. 1983 Oct;42(1):269-75.

14.

Cloning and expression of human tissue-type plasminogen activator cDNA in E. coli.

Pennica D, Holmes WE, Kohr WJ, Harkins RN, Vehar GA, Ward CA, Bennett WF, Yelverton E, Seeburg PH, Heyneker HL, Goeddel DV, Collen D.

Nature. 1983 Jan 20;301(5897):214-21. No abstract available.

PMID:
6337343
15.

Efficient bacterial expression of bovine and porcine growth hormones.

Seeburg PH, Sias S, Adelman J, de Boer HA, Hayflick J, Jhurani P, Goeddel DV, Heyneker HL.

DNA. 1983;2(1):37-45.

PMID:
6303731
16.

Patents and literature.

Rembaum A, Rohrbach RP, Klose S, Batz HG, Stoltz M, Hagen A, Weimann G, Wildman SG, Kwanyuen P, Franzmann G, Wulsmann HL, Nakanishi T, Shigemasa Y, Monsheimer R, Pfleiderer E, Yoshioka T, Teramoto K, Shimamura M, Lee CK, Tamuri M, Kanno M, Ishi Y, Kaetsu I, Kumakura M, Yoshida M, Strobel GA, Johnson DE, Srinivasan VR, Choi YC, Fukuda H, Shiotani T, Okada W, Messing RA, Oppermann RA, Simpson LB, Takeguchi MM, Bigazzi M, Higerd TB, Goust JM, Tolbert WR, Kuo MJ, Feder J, Patel RN, Hou CT, Laskin AI, Yukawa H, Osumi K, Takayama Y, Fujiwara A, Masuda S, Takaku F, Ogasa K, Kuboyama M, Saito M, Yanai N, Nishida M, Tosaka O, Ono E, Ishihara M, Morioka H, Takinami K, Taoka A, Uchida S, Puls J, Sinner M, Dietrichs HH, Wicklow DT, Detroy RW, Heady RE, Yukawa H, Osumi K, Nara T, Takayama Y, Knight E, Tsao GT, Ladisch MR, Ladisch CM, Hsu TA, Friesen HJ, Pestka S, Manis JJ, Debabov VG, Kozlov JI, Zhdanova NI, Khurges EM, Yankovsky NK, Rozinov MR, Shakulov RS, Rebentish BA, Livshits VA, Gusyatiner MM, Mashko SV, Moshentseva VN, Kozyreva LF, Arsatiants RA, Goodman HM, Shine J, Horst P, Goeddel DV, Heyneker HL.

Appl Biochem Biotechnol. 1981 Dec;6(4):339-51. doi: 10.1007/BF02798284. No abstract available.

PMID:
24233981
17.

Expression in Escherichia coli of a chemically synthesized gene for a "mini-C" analog of human proinsulin.

Wetzel R, Kleid DG, Crea R, Heyneker HL, Yansura DG, Hirose T, Kraszewski A, Riggs AD, Itakura K, Goeddel DV.

Gene. 1981 Dec;16(1-3):63-71.

PMID:
7044895
18.

Production of biologically active N alpha-desacetylthymosin alpha 1 in Escherichia coli through expression of a chemically synthesized gene.

Wetzel R, Heyneker HL, Goeddel DV, Jhurani P, Shapiro J, Crea R, Low TL, McClure JE, Thurman GB, Goldstein AL.

Biochemistry. 1980 Dec 23;19(26):6096-104.

PMID:
7008828
19.

Human leukocyte interferon produced by E. coli is biologically active.

Goeddel DV, Yelverton E, Ullrich A, Heyneker HL, Miozzari G, Holmes W, Seeburg PH, Dull T, May L, Stebbing N, Crea R, Maeda S, McCandliss R, Sloma A, Tabor JM, Gross M, Familletti PC, Pestka S.

Nature. 1980 Oct 2;287(5781):411-6.

PMID:
6159538
20.

The nucleotide sequence surrounding the replication origin of the cop3 mutant of the bacteriocinogenic plasmid Clo DF13.

Stuitje AR, Veltkamp E, Maat J, Heyneker HL.

Nucleic Acids Res. 1980 Apr 11;8(7):1459-73.

21.

Construction of new cloning vehicles with genes of the tryptophan operon of Escherichia coli as genetic markers.

Enger-Valk BE, Heyneker HL, Oosterbaan RA, Pouwels PH.

Gene. 1980 Apr;9(1-2):69-85.

PMID:
6247248
22.

Synthesis, cloning, and expression of hormone genes in Escherichia coli.

Riggs AD, Itakura K, Crea R, Hirose T, Kraszewski A, Goeddel D, Kleid D, Yansura DG, Bolivar F, Heyneker HL.

Recent Prog Horm Res. 1980;36:261-76. Review. No abstract available.

PMID:
6997943
23.

Direct expression in Escherichia coli of a DNA sequence coding for human growth hormone.

Goeddel DV, Heyneker HL, Hozumi T, Arentzen R, Itakura K, Yansura DG, Ross MJ, Miozzari G, Crea R, Seeburg PH.

Nature. 1979 Oct 18;281(5732):544-8.

PMID:
386136
24.

Characterizing wild-type and mutant promoters of the tetracycline resistance gene in pBR313.

Rodriguez RL, West RW, Heyneker HL, Bolivar F, Boyer HW.

Nucleic Acids Res. 1979 Jul 25;6(10):3267-87.

25.

Expression in Escherichia coli of chemically synthesized genes for human insulin.

Goeddel DV, Kleid DG, Bolivar F, Heyneker HL, Yansura DG, Crea R, Hirose T, Kraszewski A, Itakura K, Riggs AD.

Proc Natl Acad Sci U S A. 1979 Jan;76(1):106-10.

26.

A general method for the purification of restriction enzymes.

Greene PJ, Heyneker HL, Bolivar F, Rodriguez RL, Betlach MC, Covarrubias AA, Backman K, Russel DJ, Tait R, Boyer HW.

Nucleic Acids Res. 1978 Jul;5(7):2373-80.

27.

Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.

Itakura K, Hirose T, Crea R, Riggs AD, Heyneker HL, Bolivar F, Boyer HW.

Science. 1977 Dec 9;198(4321):1056-63.

PMID:
412251
28.

Origin of replication of pBR345 plasmid DNA.

Bolivar F, Betlach MC, Heyneker HL, Shine J, Rodriguez RL, Boyer HW.

Proc Natl Acad Sci U S A. 1977 Dec;74(12):5265-9.

29.

Interaction of bacteriophage T4 RNA and DNA ligases in joining of duplex DNA at base-paired ends.

Sugino A, Goodman HM, Heyneker HL, Shine J, Boyer HW, Cozzarelli NR.

J Biol Chem. 1977 Jun 10;252(11):3987-94.

30.

Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Bolivar F, Rodriguez RL, Greene PJ, Betlach MC, Heyneker HL, Boyer HW, Crosa JH, Falkow S.

Gene. 1977;2(2):95-113.

PMID:
344137
31.

Synthetic lac operator DNA is functional in vivo.

Heyneker HL, Shine J, Goodman HM, Boyer HW, Rosenberg J, Dickerson RE, Narang SA, Itakura K, Lin S, Riggs AD.

Nature. 1976 Oct 28;263(5580):748-52. No abstract available.

PMID:
1069185

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