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Items: 20


Mechanisms of erythrocyte development and regeneration: implications for regenerative medicine and beyond.

Bresnick EH, Hewitt KJ, Mehta C, Keles S, Paulson RF, Johnson KD.

Development. 2018 Jan 10;145(1). pii: dev151423. doi: 10.1242/dev.151423. Review.


Dissecting Regulatory Mechanisms Using Mouse Fetal Liver-Derived Erythroid Cells.

McIver SC, Hewitt KJ, Gao X, Mehta C, Zhang J, Bresnick EH.

Methods Mol Biol. 2018;1698:67-89. doi: 10.1007/978-1-4939-7428-3_4.


GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia.

Hewitt KJ, Katsumura KR, Matson DR, Devadas P, Tanimura N, Hebert AS, Coon JJ, Kim JS, Dewey CN, Keles S, Hao S, Paulson RF, Bresnick EH.

Dev Cell. 2017 Aug 7;42(3):213-225.e4. doi: 10.1016/j.devcel.2017.07.009.


The Hematopoietic Stem and Progenitor Cell Cistrome: GATA Factor-Dependent cis-Regulatory Mechanisms.

Hewitt KJ, Johnson KD, Gao X, Keles S, Bresnick EH.

Curr Top Dev Biol. 2016;118:45-76. doi: 10.1016/bs.ctdb.2016.01.002. Epub 2016 Feb 26. Review.


Cis-regulatory mechanisms governing stem and progenitor cell transitions.

Johnson KD, Kong G, Gao X, Chang YI, Hewitt KJ, Sanalkumar R, Prathibha R, Ranheim EA, Dewey CN, Zhang J, Bresnick EH.

Sci Adv. 2015 Sep 4;1(8):e1500503. doi: 10.1126/sciadv.1500503. eCollection 2015 Sep.


Hematopoietic Signaling Mechanism Revealed from a Stem/Progenitor Cell Cistrome.

Hewitt KJ, Kim DH, Devadas P, Prathibha R, Zuo C, Sanalkumar R, Johnson KD, Kang YA, Kim JS, Dewey CN, Keles S, Bresnick EH.

Mol Cell. 2015 Jul 2;59(1):62-74. doi: 10.1016/j.molcel.2015.05.020. Epub 2015 Jun 11.


Strategies for Oral Mucosal Repair by Engineering 3D Tissues with Pluripotent Stem Cells.

Hewitt KJ, Shamis Y, Gerami-Naini B, Garlick JA.

Adv Wound Care (New Rochelle). 2014 Dec 1;3(12):742-750. Review.


Epigenetic and genetic mechanisms in red cell biology.

Hewitt KJ, Sanalkumar R, Johnson KD, Keles S, Bresnick EH.

Curr Opin Hematol. 2014 May;21(3):155-64. doi: 10.1097/MOH.0000000000000034. Review.


Mechanism governing a stem cell-generating cis-regulatory element.

Sanalkumar R, Johnson KD, Gao X, Boyer ME, Chang YI, Hewitt KJ, Zhang J, Bresnick EH.

Proc Natl Acad Sci U S A. 2014 Mar 25;111(12):E1091-100. doi: 10.1073/pnas.1400065111. Epub 2014 Mar 10.


Fibroblasts derived from human pluripotent stem cells activate angiogenic responses in vitro and in vivo.

Shamis Y, Silva EA, Hewitt KJ, Brudno Y, Levenberg S, Mooney DJ, Garlick JA.

PLoS One. 2013 Dec 30;8(12):e83755. doi: 10.1371/journal.pone.0083755. eCollection 2013.


Cellular reprogramming to reset epigenetic signatures.

Hewitt KJ, Garlick JA.

Mol Aspects Med. 2013 Jul-Aug;34(4):841-8. doi: 10.1016/j.mam.2012.08.002. Epub 2012 Sep 5. Review.


PDGFRβ expression and function in fibroblasts derived from pluripotent cells is linked to DNA demethylation.

Hewitt KJ, Shamis Y, Knight E, Smith A, Maione A, Alt-Holland A, Sheridan SD, Haggarty SJ, Garlick JA.

J Cell Sci. 2012 May 1;125(Pt 9):2276-87. doi: 10.1242/jcs.099192. Epub 2012 Feb 17.


iPSC-derived fibroblasts demonstrate augmented production and assembly of extracellular matrix proteins.

Shamis Y, Hewitt KJ, Bear SE, Alt-Holland A, Qari H, Margvelashvilli M, Knight EB, Smith A, Garlick JA.

In Vitro Cell Dev Biol Anim. 2012 Feb;48(2):112-22. doi: 10.1007/s11626-011-9478-4. Epub 2012 Jan 19.


Epigenetic and phenotypic profile of fibroblasts derived from induced pluripotent stem cells.

Hewitt KJ, Shamis Y, Hayman RB, Margvelashvili M, Dong S, Carlson MW, Garlick JA.

PLoS One. 2011 Feb 28;6(2):e17128. doi: 10.1371/journal.pone.0017128.


Fibroblasts derived from human embryonic stem cells direct development and repair of 3D human skin equivalents.

Shamis Y, Hewitt KJ, Carlson MW, Margvelashvilli M, Dong S, Kuo CK, Daheron L, Egles C, Garlick JA.

Stem Cell Res Ther. 2011 Feb 21;2(1):10. doi: 10.1186/scrt51.


Three-dimensional epithelial tissues generated from human embryonic stem cells.

Hewitt KJ, Shamis Y, Carlson MW, Aberdam E, Aberdam D, Garlick JA.

Tissue Eng Part A. 2009 Nov;15(11):3417-26. doi: 10.1089/ten.TEA.2009.0060.


Wnt5A regulates expression of tumor-associated antigens in melanoma via changes in signal transducers and activators of transcription 3 phosphorylation.

Dissanayake SK, Olkhanud PB, O'Connell MP, Carter A, French AD, Camilli TC, Emeche CD, Hewitt KJ, Rosenthal DT, Leotlela PD, Wade MS, Yang SW, Brant L, Nickoloff BJ, Messina JL, Biragyn A, Hoek KS, Taub DD, Longo DL, Sondak VK, Hewitt SM, Weeraratna AT.

Cancer Res. 2008 Dec 15;68(24):10205-14. doi: 10.1158/0008-5472.CAN-08-2149.


The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

Dissanayake SK, Wade M, Johnson CE, O'Connell MP, Leotlela PD, French AD, Shah KV, Hewitt KJ, Rosenthal DT, Indig FE, Jiang Y, Nickoloff BJ, Taub DD, Trent JM, Moon RT, Bittner M, Weeraratna AT.

J Biol Chem. 2007 Jun 8;282(23):17259-71. Epub 2007 Apr 10.


The claudin gene family: expression in normal and neoplastic tissues.

Hewitt KJ, Agarwal R, Morin PJ.

BMC Cancer. 2006 Jul 12;6:186.


The effect of daily norethisterone (0.35 mg) on cervical mucus and on urinary LH, pregnanediol and oestrogen levels.

Elstein M, Briston PG, Hewitt KJ, Kirk D, Miller H.

Br J Obstet Gynaecol. 1976 Feb;83(2):165-8.


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