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Items: 1 to 50 of 255

1.

Biosynthetic machinery for C25,C25-diether archaeal lipids from the hyperthermophilic archaeon Aeropyrum pernix.

Yoshida R, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2018 Feb 7. pii: S0006-291X(18)30251-1. doi: 10.1016/j.bbrc.2018.02.028. [Epub ahead of print]

PMID:
29427665
2.

Production of ophthalmic acid using engineered Escherichia coli.

Ito T, Tokoro M, Hori R, Hemmi H, Yoshimura T.

Appl Environ Microbiol. 2018 Jan 19. pii: AEM.02806-17. doi: 10.1128/AEM.02806-17. [Epub ahead of print]

PMID:
29352090
3.

Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration.

Ishida Y, Kimura A, Nosaka M, Kuninaka Y, Hemmi H, Sasaki I, Kaisho T, Mukaida N, Kondo T.

Sci Rep. 2017 Dec 4;7(1):16833. doi: 10.1038/s41598-017-17007-8.

4.

Utilization of an intermediate of the methylerythritol phosphate pathway, (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate, as the prenyl donor substrate for various prenyltransferases.

Hayashi Y, Ito T, Yoshimura T, Hemmi H.

Biosci Biotechnol Biochem. 2017 Dec 1:1-10. doi: 10.1080/09168451.2017.1398064. [Epub ahead of print]

PMID:
29191109
5.

Ultraviolet B-Induced Maturation of CD11b-Type Langerin- Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin.

Yamazaki S, Odanaka M, Nishioka A, Kasuya S, Shime H, Hemmi H, Imai M, Riethmacher D, Kaisho T, Ohkura N, Sakaguchi S, Morita A.

J Immunol. 2018 Jan 1;200(1):119-129. doi: 10.4049/jimmunol.1701056. Epub 2017 Nov 20.

PMID:
29158419
6.

Occurrence of the (2R,3S)-Isomer of 2-Amino-3,4-dihydroxybutanoic Acid in the Mushroom Hypsizygus marmoreus.

Ito T, Yu Z, Yoshino I, Hirozawa Y, Yamamoto K, Shinoda K, Watanabe A, Hemmi H, Asada Y, Yoshimura T.

J Agric Food Chem. 2017 Aug 2;65(30):6131-6139. doi: 10.1021/acs.jafc.7b01893. Epub 2017 Jul 24.

PMID:
28686838
7.

Identification of enzymes involved in the mevalonate pathway of Flavobacterium johnsoniae.

Hayakawa H, Sobue F, Motoyama K, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2017 Jun 3;487(3):702-708. doi: 10.1016/j.bbrc.2017.04.120. Epub 2017 Apr 23.

PMID:
28442346
8.

A Single Amino Acid Mutation Converts (R)-5-Diphosphomevalonate Decarboxylase into a Kinase.

Motoyama K, Unno H, Hattori A, Takaoka T, Ishikita H, Kawaide H, Yoshimura T, Hemmi H.

J Biol Chem. 2017 Feb 10;292(6):2457-2469. doi: 10.1074/jbc.M116.752535. Epub 2016 Dec 21.

9.

Esophageal Endoscopic Submucosal Dissection Assisted by an Overtube with a Traction Forceps: An Animal Study.

Ohata K, Fu K, Sakai E, Nonaka K, Tashima T, Minato Y, Ohno A, Ito T, Tsuji Y, Chiba H, Yamawaki M, Hemmi H, Nakaya T, Fukushima J, Matsuhashi N.

Gastroenterol Res Pract. 2016;2016:3186168. doi: 10.1155/2016/3186168. Epub 2016 Jul 27.

10.

Ophthalmic acid accumulation in an Escherichia coli mutant lacking the conserved pyridoxal 5'-phosphate-binding protein YggS.

Ito T, Yamauchi A, Hemmi H, Yoshimura T.

J Biosci Bioeng. 2016 Dec;122(6):689-693. doi: 10.1016/j.jbiosc.2016.06.010. Epub 2016 Jul 12.

PMID:
27426274
11.

Isolation and structure determination of a new lantibiotic cinnamycin B from Actinomadura atramentaria based on genome mining.

Kodani S, Komaki H, Ishimura S, Hemmi H, Ohnishi-Kameyama M.

J Ind Microbiol Biotechnol. 2016 Aug;43(8):1159-65. doi: 10.1007/s10295-016-1788-9. Epub 2016 Jun 2.

PMID:
27255974
12.

Isolation and structural determination of a new antibacterial compound demethyl-L-681,217 from Streptomyces cattleya.

Sugai S, Komaki H, Hemmi H, Kodani S.

J Antibiot (Tokyo). 2016 Nov;69(11):839-842. doi: 10.1038/ja.2016.53. Epub 2016 May 25. No abstract available.

PMID:
27220410
13.

NMR analysis on the sialic acid-binding mechanism of an R-type lectin mutant by natural evolution-mimicry.

Hemmi H, Kuno A, Unno S, Hirabayashi J.

FEBS Lett. 2016 Jun;590(12):1720-8. doi: 10.1002/1873-3468.12212. Epub 2016 May 26.

14.

In Vivo Ablation of a Dendritic Cell Subset Expressing the Chemokine Receptor XCR1.

Hemmi H, Hoshino K, Kaisho T.

Methods Mol Biol. 2016;1423:247-53. doi: 10.1007/978-1-4939-3606-9_17.

PMID:
27142021
15.

A cis-prenyltransferase from Methanosarcina acetivorans catalyzes both head-to-tail and nonhead-to-tail prenyl condensation.

Ogawa T, Emi K, Koga K, Yoshimura T, Hemmi H.

FEBS J. 2016 Jun;283(12):2369-83. doi: 10.1111/febs.13749. Epub 2016 May 17.

16.

Crucial roles of XCR1-expressing dendritic cells and the XCR1-XCL1 chemokine axis in intestinal immune homeostasis.

Ohta T, Sugiyama M, Hemmi H, Yamazaki C, Okura S, Sasaki I, Fukuda Y, Orimo T, Ishii KJ, Hoshino K, Ginhoux F, Kaisho T.

Sci Rep. 2016 Mar 23;6:23505. doi: 10.1038/srep23505.

17.

Imaging of the cross-presenting dendritic cell subsets in the skin-draining lymph node.

Kitano M, Yamazaki C, Takumi A, Ikeno T, Hemmi H, Takahashi N, Shimizu K, Fraser SE, Hoshino K, Kaisho T, Okada T.

Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1044-9. doi: 10.1073/pnas.1513607113. Epub 2016 Jan 11.

18.

Microsatellite Alterations With Allelic Loss at 9p24.2 Signify Less-Aggressive Colorectal Cancer Metastasis.

Koi M, Garcia M, Choi C, Kim HR, Koike J, Hemmi H, Nagasaka T, Okugawa Y, Toiyama Y, Kitajima T, Imaoka H, Kusunoki M, Chen YH, Mukherjee B, Boland CR, Carethers JM.

Gastroenterology. 2016 Apr;150(4):944-55. doi: 10.1053/j.gastro.2015.12.032. Epub 2016 Jan 2.

19.

A phytoene desaturase homolog gene from the methanogenic archaeon Methanosarcina acetivorans is responsible for hydroxyarchaeol biosynthesis.

Mori T, Isobe K, Ogawa T, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2015 Oct 16;466(2):186-91. doi: 10.1016/j.bbrc.2015.09.001. Epub 2015 Sep 7.

PMID:
26361140
20.

In Vivo Formation of the Protein Disulfide Bond That Enhances the Thermostability of Diphosphomevalonate Decarboxylase, an Intracellular Enzyme from the Hyperthermophilic Archaeon Sulfolobus solfataricus.

Hattori A, Unno H, Goda S, Motoyama K, Yoshimura T, Hemmi H.

J Bacteriol. 2015 Nov;197(21):3463-71. doi: 10.1128/JB.00352-15. Epub 2015 Aug 24.

21.

Robust Anti-viral Immunity Requires Multiple Distinct T Cell-Dendritic Cell Interactions.

Eickhoff S, Brewitz A, Gerner MY, Klauschen F, Komander K, Hemmi H, Garbi N, Kaisho T, Germain RN, Kastenmüller W.

Cell. 2015 Sep 10;162(6):1322-37. doi: 10.1016/j.cell.2015.08.004. Epub 2015 Aug 18.

22.

A new member of MocR/GabR-type PLP-binding regulator of D-alanyl-D-alanine ligase in Brevibacillus brevis.

Takenaka T, Ito T, Miyahara I, Hemmi H, Yoshimura T.

FEBS J. 2015 Nov;282(21):4201-17. doi: 10.1111/febs.13415. Epub 2015 Sep 8.

23.

A highly selective biosynthetic pathway to non-natural C50 carotenoids assembled from moderately selective enzymes.

Furubayashi M, Ikezumi M, Takaichi S, Maoka T, Hemmi H, Ogawa T, Saito K, Tobias AV, Umeno D.

Nat Commun. 2015 Jul 14;6:7534. doi: 10.1038/ncomms8534.

24.

Structure determination of a siderophore peucechelin from Streptomyces peucetius.

Kodani S, Komaki H, Suzuki M, Kobayakawa F, Hemmi H.

Biometals. 2015 Oct;28(5):791-801. doi: 10.1007/s10534-015-9866-4. Epub 2015 Jun 18.

PMID:
26085470
25.

Domain characterization of Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator.

Okuda K, Ito T, Goto M, Takenaka T, Hemmi H, Yoshimura T.

J Biochem. 2015 Sep;158(3):225-34. doi: 10.1093/jb/mvv040. Epub 2015 Apr 23.

PMID:
25911692
26.

Isolation and structure determination of new siderophore albachelin from Amycolatopsis alba.

Kodani S, Komaki H, Suzuki M, Hemmi H, Ohnishi-Kameyama M.

Biometals. 2015 Apr;28(2):381-9. doi: 10.1007/s10534-015-9842-z. Epub 2015 Mar 7.

PMID:
25749409
27.

PEGylated D-serine dehydratase as a D-serine reducing agent.

Ito T, Takada H, Isobe K, Suzuki M, Kitaura Y, Hemmi H, Matsuda T, Sasabe J, Yoshimura T.

J Pharm Biomed Anal. 2015 Dec 10;116:34-9. doi: 10.1016/j.jpba.2014.12.044. Epub 2015 Jan 4.

PMID:
25617179
28.

Role of the aminotransferase domain in Bacillus subtilis GabR, a pyridoxal 5'-phosphate-dependent transcriptional regulator.

Okuda K, Kato S, Ito T, Shiraki S, Kawase Y, Goto M, Kawashima S, Hemmi H, Fukada H, Yoshimura T.

Mol Microbiol. 2015 Jan;95(2):245-57. doi: 10.1111/mmi.12861. Epub 2014 Dec 8.

29.

Homeostasis of thymus-derived Foxp3+ regulatory T cells is controlled by ultraviolet B exposure in the skin.

Yamazaki S, Nishioka A, Kasuya S, Ohkura N, Hemmi H, Kaisho T, Taguchi O, Sakaguchi S, Morita A.

J Immunol. 2014 Dec 1;193(11):5488-97. doi: 10.4049/jimmunol.1400985. Epub 2014 Oct 27.

30.
31.

Isolation and structural determination of a new hydrophobic peptide venepeptide from Streptomyces venezuelae.

Kodani S, Sato K, Hemmi H, Ohnish-Kameyama M.

J Antibiot (Tokyo). 2014 Dec;67(12):839-42. doi: 10.1038/ja.2014.81. Epub 2014 Jun 25. No abstract available.

PMID:
24961708
32.

Reaction mechanism of Zn2+-dependent d-serine dehydratase: role of a conserved tyrosine residue interacting with pyridine ring nitrogen of pyridoxal 5'-phosphate.

Ito T, Matsuoka M, Koga K, Hemmi H, Yoshimura T.

J Biochem. 2014 Sep;156(3):173-80. doi: 10.1093/jb/mvu035. Epub 2014 May 31.

PMID:
24881047
33.

A novel geranylgeranyl reductase from the methanogenic archaeon Methanosarcina acetivorans displays unique regiospecificity.

Ogawa T, Isobe K, Mori T, Asakawa S, Yoshimura T, Hemmi H.

FEBS J. 2014 Jul;281(14):3165-76. doi: 10.1111/febs.12851. Epub 2014 Jun 9.

34.

Olfactory plays a key role in spatiotemporal pathogenesis of cerebral malaria.

Zhao H, Aoshi T, Kawai S, Mori Y, Konishi A, Ozkan M, Fujita Y, Haseda Y, Shimizu M, Kohyama M, Kobiyama K, Eto K, Nabekura J, Horii T, Ishino T, Yuda M, Hemmi H, Kaisho T, Akira S, Kinoshita M, Tohyama K, Yoshioka Y, Ishii KJ, Coban C.

Cell Host Microbe. 2014 May 14;15(5):551-63. doi: 10.1016/j.chom.2014.04.008.

35.

Hindlimb-unloading suppresses B cell population in the bone marrow and peripheral circulation associated with OPN expression in circulating blood cells.

Ezura Y, Nagata J, Nagao M, Hemmi H, Hayata T, Rittling S, Denhardt DT, Noda M.

J Bone Miner Metab. 2015 Jan;33(1):48-54. doi: 10.1007/s00774-014-0568-8. Epub 2014 May 16.

PMID:
24831120
36.

(R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum.

Azami Y, Hattori A, Nishimura H, Kawaide H, Yoshimura T, Hemmi H.

J Biol Chem. 2014 Jun 6;289(23):15957-67. doi: 10.1074/jbc.M114.562686. Epub 2014 Apr 22.

37.

Geranylgeranyl reductase and ferredoxin from Methanosarcina acetivorans are required for the synthesis of fully reduced archaeal membrane lipid in Escherichia coli cells.

Isobe K, Ogawa T, Hirose K, Yokoi T, Yoshimura T, Hemmi H.

J Bacteriol. 2014 Jan;196(2):417-23. doi: 10.1128/JB.00927-13. Epub 2013 Nov 8.

38.

Conserved pyridoxal protein that regulates Ile and Val metabolism.

Ito T, Iimori J, Takayama S, Moriyama A, Yamauchi A, Hemmi H, Yoshimura T.

J Bacteriol. 2013 Dec;195(24):5439-49. doi: 10.1128/JB.00593-13. Epub 2013 Oct 4.

39.

Inversion of the stereochemistry around the sulfur atom of the axial methionine side chain through alteration of amino acid side chain packing in Hydrogenobacter thermophilus cytochrome C552 and its functional consequences.

Tai H, Tonegawa K, Shibata T, Hemmi H, Kobayashi N, Yamamoto Y.

Biochemistry. 2013 Jul 16;52(28):4800-9. doi: 10.1021/bi4004028. Epub 2013 Jul 5.

PMID:
23796250
40.

Substrate specificity of undecaprenyl diphosphate synthase from the hyperthermophilic archaeon Aeropyrum pernix.

Mori T, Ogawa T, Yoshimura T, Hemmi H.

Biochem Biophys Res Commun. 2013 Jun 28;436(2):230-4. doi: 10.1016/j.bbrc.2013.05.081. Epub 2013 May 31.

PMID:
23726912
41.

Critical roles of a dendritic cell subset expressing a chemokine receptor, XCR1.

Yamazaki C, Sugiyama M, Ohta T, Hemmi H, Hamada E, Sasaki I, Fukuda Y, Yano T, Nobuoka M, Hirashima T, Iizuka A, Sato K, Tanaka T, Hoshino K, Kaisho T.

J Immunol. 2013 Jun 15;190(12):6071-82. doi: 10.4049/jimmunol.1202798. Epub 2013 May 13.

42.

Biochemical evidence supporting the presence of the classical mevalonate pathway in the thermoacidophilic archaeon Sulfolobus solfataricus.

Nishimura H, Azami Y, Miyagawa M, Hashimoto C, Yoshimura T, Hemmi H.

J Biochem. 2013 May;153(5):415-20. doi: 10.1093/jb/mvt006. Epub 2013 Feb 1.

PMID:
23378249
43.

Catalytic mechanism of serine racemase from Dictyostelium discoideum.

Ito T, Maekawa M, Hayashi S, Goto M, Hemmi H, Yoshimura T.

Amino Acids. 2013 Mar;44(3):1073-84. doi: 10.1007/s00726-012-1442-4. Epub 2012 Dec 27.

PMID:
23269477
44.

Enzymatic assay for D-aspartic acid using D-aspartate oxidase and oxaloacetate decarboxylase.

Kato S, Ikuta T, Hemmi H, Takahashi S, Kera Y, Yoshimura T.

Biosci Biotechnol Biochem. 2012;76(11):2150-2. Epub 2012 Nov 7.

45.

NMR structure and dynamics of the C-terminal domain of R-type lectin from the earthworm Lumbricus terrestris.

Hemmi H, Kuno A, Hirabayashi J.

FEBS J. 2013 Jan;280(1):70-82. doi: 10.1111/febs.12050. Epub 2012 Nov 23.

46.

Spi-B is critical for plasmacytoid dendritic cell function and development.

Sasaki I, Hoshino K, Sugiyama T, Yamazaki C, Yano T, Iizuka A, Hemmi H, Tanaka T, Saito M, Sugiyama M, Fukuda Y, Ohta T, Sato K, Ainai A, Suzuki T, Hasegawa H, Toyama-Sorimachi N, Kohara H, Nagasawa T, Kaisho T.

Blood. 2012 Dec 6;120(24):4733-43. doi: 10.1182/blood-2012-06-436527. Epub 2012 Oct 11.

47.

Lysine racemase from a lactic acid bacterium, Oenococcus oeni: structural basis of substrate specificity.

Kato S, Hemmi H, Yoshimura T.

J Biochem. 2012 Dec;152(6):505-8. doi: 10.1093/jb/mvs120. Epub 2012 Oct 3.

PMID:
23035128
48.

Interaction between the heme and a G-quartet in a heme-DNA complex.

Saito K, Tai H, Hemmi H, Kobayashi N, Yamamoto Y.

Inorg Chem. 2012 Aug 6;51(15):8168-76. doi: 10.1021/ic3005739. Epub 2012 Jul 25.

PMID:
22830520
49.

Profilin1 regulates sternum development and endochondral bone formation.

Miyajima D, Hayata T, Suzuki T, Hemmi H, Nakamoto T, Notomi T, Amagasa T, Böttcher RT, Costell M, Fässler R, Ezura Y, Noda M.

J Biol Chem. 2012 Sep 28;287(40):33545-53. Epub 2012 Jul 6.

50.

MicroRNA-200c modulates epithelial-to-mesenchymal transition (EMT) in human colorectal cancer metastasis.

Hur K, Toiyama Y, Takahashi M, Balaguer F, Nagasaka T, Koike J, Hemmi H, Koi M, Boland CR, Goel A.

Gut. 2013 Sep;62(9):1315-26. doi: 10.1136/gutjnl-2011-301846. Epub 2012 Jun 26.

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