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Items: 1 to 50 of 276

1.

Photoactivatable Rhodamine Spiroamides and Diazoketones Decorated with "Universal Hydrophilizer" or Hydroxyl Groups.

Roubinet B, Bischoff M, Nizamov S, Yan S, Geisler C, Stoldt S, Mitronova GY, Belov VN, Bossi ML, Hell SW.

J Org Chem. 2018 May 11. doi: 10.1021/acs.joc.8b00756. [Epub ahead of print]

PMID:
29749224
2.

STED nanoscopy of the centrosome linker reveals a CEP68-organized, periodic rootletin network anchored to a C-Nap1 ring at centrioles.

Vlijm R, Li X, Panic M, Rüthnick D, Hata S, Herrmannsdörfer F, Kuner T, Heilemann M, Engelhardt J, Hell SW, Schiebel E.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):E2246-E2253. doi: 10.1073/pnas.1716840115. Epub 2018 Feb 20.

3.

Novel reversibly switchable fluorescent proteins for RESOLFT and STED nanoscopy engineered from the bacterial photoreceptor YtvA.

Gregor C, Sidenstein SC, Andresen M, Sahl SJ, Danzl JG, Hell SW.

Sci Rep. 2018 Feb 9;8(1):2724. doi: 10.1038/s41598-018-19947-1.

4.

PONy Dyes: Direct Addition of P(III) Nucleophiles to Organic Fluorophores.

Butkevich AN, Sednev MV, Shojaei H, Belov VN, Hell SW.

Org Lett. 2018 Feb 16;20(4):1261-1264. doi: 10.1021/acs.orglett.8b00270. Epub 2018 Feb 6.

PMID:
29405716
5.

Quantitative optical nanophysiology of Ca2+ signaling at inner hair cell active zones.

Neef J, Urban NT, Ohn TL, Frank T, Jean P, Hell SW, Willig KI, Moser T.

Nat Commun. 2018 Jan 18;9(1):290. doi: 10.1038/s41467-017-02612-y.

6.

Strongly enhanced bacterial bioluminescence with the ilux operon for single-cell imaging.

Gregor C, Gwosch KC, Sahl SJ, Hell SW.

Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):962-967. doi: 10.1073/pnas.1715946115. Epub 2018 Jan 16.

7.

Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy.

Richter KN, Revelo NH, Seitz KJ, Helm MS, Sarkar D, Saleeb RS, D'Este E, Eberle J, Wagner E, Vogl C, Lazaro DF, Richter F, Coy-Vergara J, Coceano G, Boyden ES, Duncan RR, Hell SW, Lauterbach MA, Lehnart SE, Moser T, Outeiro TF, Rehling P, Schwappach B, Testa I, Zapiec B, Rizzoli SO.

EMBO J. 2018 Jan 4;37(1):139-159. doi: 10.15252/embj.201695709. Epub 2017 Nov 16.

8.

High-Affinity Functional Fluorescent Ligands for Human β-Adrenoceptors.

Mitronova GY, Lukinavičius G, Butkevich AN, Kohl T, Belov VN, Lehnart SE, Hell SW.

Sci Rep. 2017 Sep 26;7(1):12319. doi: 10.1038/s41598-017-12468-3.

9.

Two-Color 810 nm STED Nanoscopy of Living Cells with Endogenous SNAP-Tagged Fusion Proteins.

Butkevich AN, Ta H, Ratz M, Stoldt S, Jakobs S, Belov VN, Hell SW.

ACS Chem Biol. 2018 Feb 16;13(2):475-480. doi: 10.1021/acschembio.7b00616. Epub 2017 Oct 2.

PMID:
28933823
10.

SRpHi ratiometric pH biosensors for super-resolution microscopy.

Richardson DS, Gregor C, Winter FR, Urban NT, Sahl SJ, Willig KI, Hell SW.

Nat Commun. 2017 Sep 18;8(1):577. doi: 10.1038/s41467-017-00606-4.

11.

Photobleaching in STED nanoscopy and its dependence on the photon flux applied for reversible silencing of the fluorophore.

Oracz J, Westphal V, Radzewicz C, Sahl SJ, Hell SW.

Sci Rep. 2017 Sep 12;7(1):11354. doi: 10.1038/s41598-017-09902-x.

12.

Fluorescence nanoscopy in cell biology.

Sahl SJ, Hell SW, Jakobs S.

Nat Rev Mol Cell Biol. 2017 Nov;18(11):685-701. doi: 10.1038/nrm.2017.71. Epub 2017 Sep 6. Review.

PMID:
28875992
13.

Stable Positioning of Unc13 Restricts Synaptic Vesicle Fusion to Defined Release Sites to Promote Synchronous Neurotransmission.

Reddy-Alla S, Böhme MA, Reynolds E, Beis C, Grasskamp AT, Mampell MM, Maglione M, Jusyte M, Rey U, Babikir H, McCarthy AW, Quentin C, Matkovic T, Bergeron DD, Mushtaq Z, Göttfert F, Owald D, Mielke T, Hell SW, Sigrist SJ, Walter AM.

Neuron. 2017 Sep 13;95(6):1350-1364.e12. doi: 10.1016/j.neuron.2017.08.016. Epub 2017 Aug 31.

PMID:
28867551
14.

Adaptive-illumination STED nanoscopy.

Heine J, Reuss M, Harke B, D'Este E, Sahl SJ, Hell SW.

Proc Natl Acad Sci U S A. 2017 Sep 12;114(37):9797-9802. doi: 10.1073/pnas.1708304114. Epub 2017 Aug 28.

15.

Cell-Permeant Large Stokes Shift Dyes for Transfection-Free Multicolor Nanoscopy.

Butkevich AN, Lukinavičius G, D'Este E, Hell SW.

J Am Chem Soc. 2017 Sep 13;139(36):12378-12381. doi: 10.1021/jacs.7b06412. Epub 2017 Aug 30.

PMID:
28845665
16.

Superresolution optical magnetic imaging and spectroscopy using individual electronic spins in diamond.

Jaskula JC, Bauch E, Arroyo-Camejo S, Lukin MD, Hell SW, Trifonov AS, Walsworth RL.

Opt Express. 2017 May 15;25(10):11048-11064. doi: 10.1364/OE.25.011048.

PMID:
28788790
17.

Fluorescent Photoswitchable Diarylethenes for Biolabeling and Single-Molecule Localization Microscopies with Optical Superresolution.

Roubinet B, Weber M, Shojaei H, Bates M, Bossi ML, Belov VN, Irie M, Hell SW.

J Am Chem Soc. 2017 May 17;139(19):6611-6620. doi: 10.1021/jacs.7b00274. Epub 2017 May 4.

PMID:
28437075
18.

Multicolour nanoscopy of fixed and living cells with a single STED beam and hyperspectral detection.

Winter FR, Loidolt M, Westphal V, Butkevich AN, Gregor C, Sahl SJ, Hell SW.

Sci Rep. 2017 Apr 18;7:46492. doi: 10.1038/srep46492.

19.

Hydroxylated Fluorescent Dyes for Live-Cell Labeling: Synthesis, Spectra and Super-Resolution STED.

Butkevich AN, Belov VN, Kolmakov K, Sokolov VV, Shojaei H, Sidenstein SC, Kamin D, Matthias J, Vlijm R, Engelhardt J, Hell SW.

Chemistry. 2017 Sep 7;23(50):12114-12119. doi: 10.1002/chem.201701216. Epub 2017 May 2.

20.

Achromatic light patterning and improved image reconstruction for parallelized RESOLFT nanoscopy.

Chmyrov A, Leutenegger M, Grotjohann T, Schönle A, Keller-Findeisen J, Kastrup L, Jakobs S, Donnert G, Sahl SJ, Hell SW.

Sci Rep. 2017 Mar 20;7:44619. doi: 10.1038/srep44619.

21.

Ground State Depletion Nanoscopy Resolves Semiconductor Nanowire Barcode Segments at Room Temperature.

Oracz J, Adolfsson K, Westphal V, Radzewicz C, Borgström MT, Sahl SJ, Prinz CN, Hell SW.

Nano Lett. 2017 Apr 12;17(4):2652-2659. doi: 10.1021/acs.nanolett.7b00468. Epub 2017 Mar 9.

22.

Strong signal increase in STED fluorescence microscopy by imaging regions of subdiffraction extent.

Göttfert F, Pleiner T, Heine J, Westphal V, Görlich D, Sahl SJ, Hell SW.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2125-2130. doi: 10.1073/pnas.1621495114. Epub 2017 Feb 13.

23.

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+ influx through cyclic nucleotide-gated channels.

Bader A, Bintig W, Begandt D, Klett A, Siller IG, Gregor C, Schaarschmidt F, Weksler B, Romero I, Couraud PO, Hell SW, Ngezahayo A.

J Physiol. 2017 Apr 15;595(8):2497-2517. doi: 10.1113/JP273150. Epub 2017 Feb 14.

24.

Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes.

Balzarotti F, Eilers Y, Gwosch KC, Gynnå AH, Westphal V, Stefani FD, Elf J, Hell SW.

Science. 2017 Feb 10;355(6325):606-612. doi: 10.1126/science.aak9913. Epub 2016 Dec 22.

PMID:
28008086
25.

Ultrastructural anatomy of nodes of Ranvier in the peripheral nervous system as revealed by STED microscopy.

D'Este E, Kamin D, Balzarotti F, Hell SW.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):E191-E199. doi: 10.1073/pnas.1619553114. Epub 2016 Dec 21.

26.

Bichromophoric Compounds with Orthogonally and Parallelly Arranged Chromophores Separated by Rigid Spacers.

Meineke DN, Bossi ML, Ta H, Belov VN, Hell SW.

Chemistry. 2017 Feb 16;23(10):2469-2475. doi: 10.1002/chem.201605587. Epub 2017 Jan 20.

PMID:
27922726
27.

Carboxylated Photoswitchable Diarylethenes for Biolabeling and Super-Resolution RESOLFT Microscopy.

Roubinet B, Bossi ML, Alt P, Leutenegger M, Shojaei H, Schnorrenberg S, Nizamov S, Irie M, Belov VN, Hell SW.

Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15429-15433. doi: 10.1002/anie.201607940. Epub 2016 Oct 21.

28.

Active zone scaffolds differentially accumulate Unc13 isoforms to tune Ca(2+) channel-vesicle coupling.

Böhme MA, Beis C, Reddy-Alla S, Reynolds E, Mampell MM, Grasskamp AT, Lützkendorf J, Bergeron DD, Driller JH, Babikir H, Göttfert F, Robinson IM, O'Kane CJ, Hell SW, Wahl MC, Stelzl U, Loll B, Walter AM, Sigrist SJ.

Nat Neurosci. 2016 Oct;19(10):1311-20. doi: 10.1038/nn.4364. Epub 2016 Aug 15.

PMID:
27526206
29.

Stimulated Emission Depletion Nanoscopy Reveals Time-Course of Human Immunodeficiency Virus Proteolytic Maturation.

Hanne J, Göttfert F, Schimer J, Anders-Össwein M, Konvalinka J, Engelhardt J, Müller B, Hell SW, Kräusslich HG.

ACS Nano. 2016 Sep 27;10(9):8215-22. doi: 10.1021/acsnano.6b03850. Epub 2016 Aug 16.

PMID:
27517329
30.

Fluorogenic Probes for Multicolor Imaging in Living Cells.

Lukinavičius G, Reymond L, Umezawa K, Sallin O, D'Este E, Göttfert F, Ta H, Hell SW, Urano Y, Johnsson K.

J Am Chem Soc. 2016 Aug 3;138(30):9365-8. doi: 10.1021/jacs.6b04782. Epub 2016 Jul 21.

PMID:
27420907
31.

"Reduced" Coumarin Dyes with an O-Phosphorylated 2,2-Dimethyl-4-(hydroxymethyl)-1,2,3,4-tetrahydroquinoline Fragment: Synthesis, Spectra, and STED Microscopy.

Nizamov S, Sednev MV, Bossi ML, Hebisch E, Frauendorf H, Lehnart SE, Belov VN, Hell SW.

Chemistry. 2016 Aug 8;22(33):11631-42. doi: 10.1002/chem.201601252. Epub 2016 Jul 7.

PMID:
27385071
32.

In vivo super-resolution RESOLFT microscopy of Drosophila melanogaster.

Schnorrenberg S, Grotjohann T, Vorbrüggen G, Herzig A, Hell SW, Jakobs S.

Elife. 2016 Jun 29;5. pii: e15567. doi: 10.7554/eLife.15567.

33.

Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.

Steshenko O, Andrade DM, Honigmann A, Mueller V, Schneider F, Sezgin E, Hell SW, Simons M, Eggeling C.

Biophys J. 2016 Jun 7;110(11):2441-2450. doi: 10.1016/j.bpj.2016.04.047.

34.

Multicolour Multilevel STED nanoscopy of Actin/Spectrin Organization at Synapses.

Sidenstein SC, D'Este E, Böhm MJ, Danzl JG, Belov VN, Hell SW.

Sci Rep. 2016 May 25;6:26725. doi: 10.1038/srep26725.

35.

Breaking the diffraction limit of light-sheet fluorescence microscopy by RESOLFT.

Hoyer P, de Medeiros G, Balázs B, Norlin N, Besir C, Hanne J, Kräusslich HG, Engelhardt J, Sahl SJ, Hell SW, Hufnagel L.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3442-6. doi: 10.1073/pnas.1522292113. Epub 2016 Mar 16.

36.

Subcortical cytoskeleton periodicity throughout the nervous system.

D'Este E, Kamin D, Velte C, Göttfert F, Simons M, Hell SW.

Sci Rep. 2016 Mar 7;6:22741. doi: 10.1038/srep22741.

37.

Fluorescent Rhodamines and Fluorogenic Carbopyronines for Super-Resolution STED Microscopy in Living Cells.

Butkevich AN, Mitronova GY, Sidenstein SC, Klocke JL, Kamin D, Meineke DN, D'Este E, Kraemer PT, Danzl JG, Belov VN, Hell SW.

Angew Chem Int Ed Engl. 2016 Mar 1;55(10):3290-4. doi: 10.1002/anie.201511018. Epub 2016 Feb 4.

38.

4Pi-RESOLFT nanoscopy.

Böhm U, Hell SW, Schmidt R.

Nat Commun. 2016 Feb 1;7:10504. doi: 10.1038/ncomms10504.

39.

isoSTED nanoscopy with intrinsic beam alignment.

Curdt F, Herr SJ, Lutz T, Schmidt R, Engelhardt J, Sahl SJ, Hell SW.

Opt Express. 2015 Nov 30;23(24):30891-903. doi: 10.1364/OE.23.030891.

PMID:
26698722
40.

Super-resolution Microscopy of Clickable Amino Acids Reveals the Effects of Fluorescent Protein Tagging on Protein Assemblies.

Vreja IC, Nikić I, Göttfert F, Bates M, Kröhnert K, Outeiro TF, Hell SW, Lemke EA, Rizzoli SO.

ACS Nano. 2015 Nov 24;9(11):11034-41. doi: 10.1021/acsnano.5b04434. Epub 2015 Oct 28.

PMID:
26498474
41.

Fluorescent dyes with large Stokes shifts for super-resolution optical microscopy of biological objects: a review.

Sednev MV, Belov VN, Hell SW.

Methods Appl Fluoresc. 2015 Oct 22;3(4):042004. doi: 10.1088/2050-6120/3/4/042004.

PMID:
29148519
42.

Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function.

Muhammad K, Reddy-Alla S, Driller JH, Schreiner D, Rey U, Böhme MA, Hollmann C, Ramesh N, Depner H, Lützkendorf J, Matkovic T, Götz T, Bergeron DD, Schmoranzer J, Goettfert F, Holt M, Wahl MC, Hell SW, Scheiffele P, Walter AM, Loll B, Sigrist SJ.

Nat Commun. 2015 Oct 16;6:8362. doi: 10.1038/ncomms9362.

43.

SiR-Hoechst is a far-red DNA stain for live-cell nanoscopy.

Lukinavičius G, Blaukopf C, Pershagen E, Schena A, Reymond L, Derivery E, Gonzalez-Gaitan M, D'Este E, Hell SW, Gerlich DW, Johnsson K.

Nat Commun. 2015 Oct 1;6:8497. doi: 10.1038/ncomms9497.

44.

RESOLFT Nanoscopy of Fixed Cells Using a Z-Domain Based Fusion Protein for Labelling.

Ilgen P, Grotjohann T, Jans DC, Kilisch M, Hell SW, Jakobs S.

PLoS One. 2015 Sep 16;10(9):e0136233. doi: 10.1371/journal.pone.0136233. eCollection 2015.

45.

A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones.

Siebert M, Böhme MA, Driller JH, Babikir H, Mampell MM, Rey U, Ramesh N, Matkovic T, Holton N, Reddy-Alla S, Göttfert F, Kamin D, Quentin C, Klinedinst S, Andlauer TF, Hell SW, Collins CA, Wahl MC, Loll B, Sigrist SJ.

Elife. 2015 Aug 14;4. doi: 10.7554/eLife.06935.

46.

Far-Red Emitting Fluorescent Dyes for Optical Nanoscopy: Fluorinated Silicon-Rhodamines (SiRF Dyes) and Phosphorylated Oxazines.

Kolmakov K, Hebisch E, Wolfram T, Nordwig LA, Wurm CA, Ta H, Westphal V, Belov VN, Hell SW.

Chemistry. 2015 Sep 14;21(38):13344-56. doi: 10.1002/chem.201501394. Epub 2015 Aug 13.

PMID:
26272226
47.

Mapping molecules in scanning far-field fluorescence nanoscopy.

Ta H, Keller J, Haltmeier M, Saka SK, Schmied J, Opazo F, Tinnefeld P, Munk A, Hell SW.

Nat Commun. 2015 Aug 13;6:7977. doi: 10.1038/ncomms8977.

48.

STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics.

Vicidomini G, Ta H, Honigmann A, Mueller V, Clausen MP, Waithe D, Galiani S, Sezgin E, Diaspro A, Hell SW, Eggeling C.

Nano Lett. 2015 Sep 9;15(9):5912-8. doi: 10.1021/acs.nanolett.5b02001. Epub 2015 Aug 7.

49.

Ultrafast, temporally stochastic STED nanoscopy of millisecond dynamics.

Schneider J, Zahn J, Maglione M, Sigrist SJ, Marquard J, Chojnacki J, Kräusslich HG, Sahl SJ, Engelhardt J, Hell SW.

Nat Methods. 2015 Sep;12(9):827-30. doi: 10.1038/nmeth.3481. Epub 2015 Jul 27.

PMID:
26214129
50.

Cortical actin networks induce spatio-temporal confinement of phospholipids in the plasma membrane--a minimally invasive investigation by STED-FCS.

Andrade DM, Clausen MP, Keller J, Mueller V, Wu C, Bear JE, Hell SW, Lagerholm BC, Eggeling C.

Sci Rep. 2015 Jun 29;5:11454. doi: 10.1038/srep11454.

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