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Items: 18

1.

Role of obesity in smoking behaviour: Mendelian randomisation study in UK Biobank.

Carreras-Torres R, Johansson M, Haycock PC, Relton CL, Davey Smith G, Brennan P, Martin RM.

BMJ. 2018 May 16;361:k1767. doi: 10.1136/bmj.k1767.

2.

Circulating vitamin D concentration and risk of seven cancers: Mendelian randomisation study.

Dimitrakopoulou VI, Tsilidis KK, Haycock PC, Dimou NL, Al-Dabhani K, Martin RM, Lewis SJ, Gunter MJ, Mondul A, Shui IM, Theodoratou E, Nimptsch K, Lindström S, Albanes D, Kühn T, Key TJ, Travis RC, Vimaleswaran KS; GECCO Consortium; PRACTICAL Consortium; GAME-ON Network (CORECT, DRIVE, ELLIPSE, FOCI-OCAC, TRICL-ILCCO), Kraft P, Pierce BL, Schildkraut JM.

BMJ. 2017 Oct 31;359:j4761. doi: 10.1136/bmj.j4761.

3.

The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study.

Carreras-Torres R, Johansson M, Gaborieau V, Haycock PC, Wade KH, Relton CL, Martin RM, Davey Smith G, Brennan P.

J Natl Cancer Inst. 2017 Sep 1;109(9). doi: 10.1093/jnci/djx012.

4.

Telomere Length and Risk of Cancer and Non-neoplastic Diseases: Is Survivin the Ariadne's Thread?-Reply.

Haycock PC, Hemani G, Aviv A.

JAMA Oncol. 2017 Dec 1;3(12):1741-1742. doi: 10.1001/jamaoncol.2017.2316. No abstract available.

PMID:
28796865
5.

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

Noyce AJ, Kia DA, Hemani G, Nicolas A, Price TR, De Pablo-Fernandez E, Haycock PC, Lewis PA, Foltynie T, Davey Smith G; International Parkinson Disease Genomics Consortium, Schrag A, Lees AJ, Hardy J, Singleton A, Nalls MA, Pearce N, Lawlor DA, Wood NW.

PLoS Med. 2017 Jun 13;14(6):e1002314. doi: 10.1371/journal.pmed.1002314. eCollection 2017 Jun.

6.

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.

Carreras-Torres R, Johansson M, Haycock PC, Wade KH, Relton CL, Martin RM, Davey Smith G, Albanes D, Aldrich MC, Andrew A, Arnold SM, Bickeböller H, Bojesen SE, Brunnström H, Manjer J, Brüske I, Caporaso NE, Chen C, Christiani DC, Christian WJ, Doherty JA, Duell EJ, Field JK, Davies MPA, Marcus MW, Goodman GE, Grankvist K, Haugen A, Hong YC, Kiemeney LA, van der Heijden EHFM, Kraft P, Johansson MB, Lam S, Landi MT, Lazarus P, Le Marchand L, Liu G, Melander O, Park SL, Rennert G, Risch A, Haura EB, Scelo G, Zaridze D, Mukeriya A, Savić M, Lissowska J, Swiatkowska B, Janout V, Holcatova I, Mates D, Schabath MB, Shen H, Tardon A, Teare MD, Woll P, Tsao MS, Wu X, Yuan JM, Hung RJ, Amos CI, McKay J, Brennan P.

PLoS One. 2017 Jun 8;12(6):e0177875. doi: 10.1371/journal.pone.0177875. eCollection 2017.

7.

Apolipoprotein(a) isoform size, lipoprotein(a) concentration, and coronary artery disease: a mendelian randomisation analysis.

Saleheen D, Haycock PC, Zhao W, Rasheed A, Taleb A, Imran A, Abbas S, Majeed F, Akhtar S, Qamar N, Zaman KS, Yaqoob Z, Saghir T, Rizvi SNH, Memon A, Mallick NH, Ishaq M, Rasheed SZ, Memon FU, Mahmood K, Ahmed N, Frossard P, Tsimikas S, Witztum JL, Marcovina S, Sandhu M, Rader DJ, Danesh J.

Lancet Diabetes Endocrinol. 2017 Jul;5(7):524-533. doi: 10.1016/S2213-8587(17)30088-8. Epub 2017 Apr 10. Erratum in: Lancet Diabetes Endocrinol. 2017 Sep;5(9):e6.

8.

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Telomeres Mendelian Randomization Collaboration, Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE, Cho MH, Hui J, Ferreira MA, Thompson PJ, Morrison AC, Felix JF, Smith NL, Christiano AM, Petukhova L, Betz RC, Fan X, Zhang X, Zhu C, Langefeld CD, Thompson SD, Wang F, Lin X, Schwartz DA, Fingerlin T, Rotter JI, Cotch MF, Jensen RA, Munz M, Dommisch H, Schaefer AS, Han F, Ollila HM, Hillary RP, Albagha O, Ralston SH, Zeng C, Zheng W, Shu XO, Reis A, Uebe S, Hüffmeier U, Kawamura Y, Otowa T, Sasaki T, Hibberd ML, Davila S, Xie G, Siminovitch K, Bei JX, Zeng YX, Försti A, Chen B, Landi S, Franke A, Fischer A, Ellinghaus D, Flores C, Noth I, Ma SF, Foo JN, Liu J, Kim JW, Cox DG, Delattre O, Mirabeau O, Skibola CF, Tang CS, Garcia-Barcelo M, Chang KP, Su WH, Chang YS, Martin NG, Gordon S, Wade TD, Lee C, Kubo M, Cha PC, Nakamura Y, Levy D, Kimura M, Hwang SJ, Hunt S, Spector T, Soranzo N, Manichaikul AW, Barr RG, Kahali B, Speliotes E, Yerges-Armstrong LM, Cheng CY, Jonas JB, Wong TY, Fogh I, Lin K, Powell JF, Rice K, Relton CL, Martin RM, Davey Smith G.

JAMA Oncol. 2017 May 1;3(5):636-651. doi: 10.1001/jamaoncol.2016.5945.

9.

Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort.

Taylor M, Simpkin AJ, Haycock PC, Dudbridge F, Zuccolo L.

PLoS One. 2016 Nov 30;11(11):e0167360. doi: 10.1371/journal.pone.0167360. eCollection 2016.

10.

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

Zheng J, Erzurumluoglu AM, Elsworth BL, Kemp JP, Howe L, Haycock PC, Hemani G, Tansey K, Laurin C; Early Genetics and Lifecourse Epidemiology (EAGLE) Eczema Consortium, Pourcain BS, Warrington NM, Finucane HK, Price AL, Bulik-Sullivan BK, Anttila V, Paternoster L, Gaunt TR, Evans DM, Neale BM.

Bioinformatics. 2017 Jan 15;33(2):272-279. doi: 10.1093/bioinformatics/btw613. Epub 2016 Sep 22.

11.

The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study.

Carreras-Torres R, Haycock PC, Relton CL, Martin RM, Smith GD, Kraft P, Gao C, Tworoger S, Le Marchand L, Wilkens LR, Park SL, Haiman C, Field JK, Davies M, Marcus M, Liu G, Caporaso NE, Christiani DC, Wei Y, Chen C, Doherty JA, Severi G, Goodman GE, Hung RJ, Amos CI, McKay J, Johansson M, Brennan P.

Sci Rep. 2016 Aug 4;6:31121. doi: 10.1038/srep31121.

12.

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator.

Bowden J, Davey Smith G, Haycock PC, Burgess S.

Genet Epidemiol. 2016 May;40(4):304-14. doi: 10.1002/gepi.21965. Epub 2016 Apr 7.

13.

Best (but oft-forgotten) practices: the design, analysis, and interpretation of Mendelian randomization studies.

Haycock PC, Burgess S, Wade KH, Bowden J, Relton C, Davey Smith G.

Am J Clin Nutr. 2016 Apr;103(4):965-78.

14.

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts.

Fasanelli F, Baglietto L, Ponzi E, Guida F, Campanella G, Johansson M, Grankvist K, Johansson M, Assumma MB, Naccarati A, Chadeau-Hyam M, Ala U, Faltus C, Kaaks R, Risch A, De Stavola B, Hodge A, Giles GG, Southey MC, Relton CL, Haycock PC, Lund E, Polidoro S, Sandanger TM, Severi G, Vineis P.

Nat Commun. 2015 Dec 15;6:10192. doi: 10.1038/ncomms10192.

15.

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis.

Haycock PC, Heydon EE, Kaptoge S, Butterworth AS, Thompson A, Willeit P.

BMJ. 2014 Jul 8;349:g4227. doi: 10.1136/bmj.g4227. Review.

16.

The association between circulating lipoprotein(a) and type 2 diabetes: is it causal?

Ye Z, Haycock PC, Gurdasani D, Pomilla C, Boekholdt SM, Tsimikas S, Khaw KT, Wareham NJ, Sandhu MS, Forouhi NG.

Diabetes. 2014 Jan;63(1):332-342. doi: 10.2337/db13-1144. Epub 2013 Oct 2.

17.

Fetal alcohol spectrum disorders: the epigenetic perspective.

Haycock PC.

Biol Reprod. 2009 Oct;81(4):607-17. doi: 10.1095/biolreprod.108.074690. Epub 2009 May 20. Review.

PMID:
19458312
18.

Exposure of mouse embryos to ethanol during preimplantation development: effect on DNA methylation in the h19 imprinting control region.

Haycock PC, Ramsay M.

Biol Reprod. 2009 Oct;81(4):618-27. doi: 10.1095/biolreprod.108.074682. Epub 2009 Mar 11.

PMID:
19279321

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