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Items: 1 to 50 of 872

1.

Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis.

Lannagan TRM, Lee YK, Wang T, Roper J, Bettington ML, Fennell L, Vrbanac L, Jonavicius L, Somashekar R, Gieniec K, Yang M, Ng JQ, Suzuki N, Ichinose M, Wright JA, Kobayashi H, Putoczki TL, Hayakawa Y, Leedham SJ, Abud HE, Yilmaz ÖH, Marker J, Klebe S, Wirapati P, Mukherjee S, Tejpar S, Leggett BA, Whitehall VLJ, Worthley DL, Woods SL.

Gut. 2018 Apr 17. pii: gutjnl-2017-315920. doi: 10.1136/gutjnl-2017-315920. [Epub ahead of print]

PMID:
29666172
2.

Efficacy of Vonoprazan for Gastroesophageal Reflux Symptoms in Patients with Proton Pump Inhibitor-resistant Non-erosive Reflux Disease.

Niikura R, Yamada A, Hirata Y, Hayakawa Y, Takahashi A, Shinozaki T, Takeuchi Y, Fujishiro M, Koike K.

Intern Med. 2018 Mar 30. doi: 10.2169/internalmedicine.0492-17. [Epub ahead of print]

3.

Novel biomarker, phosphorylated T-LAK cell-originated protein kinase (p-TOPK) can predict outcome in primary central nervous system lymphoma.

Koh M, Hayakawa Y, Akai T, Hayashi T, Tomita T, Nagai S, Kuroda S.

Neuropathology. 2018 Mar 25. doi: 10.1111/neup.12463. [Epub ahead of print]

PMID:
29575092
4.

Sessile serrated adenoma detection rate is correlated with adenoma detection rate.

Ohki D, Tsuji Y, Shinozaki T, Sakaguchi Y, Minatsuki C, Kinoshita H, Niimi K, Ono S, Hayakawa Y, Yoshida S, Yamada A, Kodashima S, Yamamichi N, Hirata Y, Ushiku T, Fujishiro M, Fukayama M, Koike K.

World J Gastrointest Oncol. 2018 Mar 15;10(3):82-90. doi: 10.4251/wjgo.v10.i3.82.

5.

The relationship of waist circumference and body mass index to grey matter volume in community dwelling adults with mild obesity.

Hayakawa YK, Sasaki H, Takao H, Yoshikawa T, Hayashi N, Mori H, Kunimatsu A, Aoki S, Ohtomo K.

Obes Sci Pract. 2017 Dec 29;4(1):97-105. doi: 10.1002/osp4.145. eCollection 2018 Feb.

6.

Identification of Tumoricidal TCRs from Tumor-Infiltrating Lymphocytes by Single-Cell Analysis.

Shitaoka K, Hamana H, Kishi H, Hayakawa Y, Kobayashi E, Sukegawa K, Piao X, Lyu F, Nagata T, Sugiyama D, Nishikawa H, Tanemura A, Katayama I, Murahashi M, Takamatsu Y, Tani K, Ozawa T, Muraguchi A.

Cancer Immunol Res. 2018 Apr;6(4):378-388. doi: 10.1158/2326-6066.CIR-17-0489. Epub 2018 Feb 23.

PMID:
29475880
7.

Doppler-free spectroscopy of metastable Sr atoms using a hollow cathode lamp.

Hayakawa Y, Sato T, Watanabe C, Aoki T, Torii Y.

Appl Opt. 2018 Feb 20;57(6):1450-1454. doi: 10.1364/AO.57.001450.

PMID:
29469847
8.

The Drosophila cytokine, GBP: A model that illuminates the yin-yang of inflammation and longevity in humans?

Shears SB, Hayakawa Y.

Cytokine. 2018 Feb 15. pii: S1043-4666(18)30056-5. doi: 10.1016/j.cyto.2018.02.016. [Epub ahead of print]

PMID:
29456061
9.

Distinct Chemopreventive Effects of Aspirin in Diffuse and Intestinal-Type Gastric Cancer.

Niikura R, Hayakawa Y, Hirata Y, Konishi M, Suzuki N, Ihara S, Yamada A, Ushiku T, Fujishiro M, Fukayama M, Koike K.

Cancer Prev Res (Phila). 2018 Feb 16. doi: 10.1158/1940-6207.CAPR-17-0276. [Epub ahead of print]

PMID:
29453233
10.

Paclitaxel-induced hypothermia and hypoperfusion increase breast cancer metastasis and angiogenesis in mice.

Ami N, Sato H, Hayakawa Y.

Oncol Lett. 2018 Feb;15(2):2330-2334. doi: 10.3892/ol.2017.7621. Epub 2017 Dec 14.

11.

Targeting the T-Lak cell originated protein kinase by OTS964 shrinks the size of power-law coded heterogeneous glioma stem cell populations.

Sugimori M, Hayakawa Y, Koh M, Hayashi T, Tamura R, Kuroda S.

Oncotarget. 2017 Dec 9;9(3):3043-3059. doi: 10.18632/oncotarget.23077. eCollection 2018 Jan 9.

12.

NK Cells Control Tumor-Promoting Function of Neutrophils in Mice.

Ogura K, Sato-Matsushita M, Yamamoto S, Hori T, Sasahara M, Iwakura Y, Saiki I, Tahara H, Hayakawa Y.

Cancer Immunol Res. 2018 Jan 23. doi: 10.1158/2326-6066.CIR-17-0204. [Epub ahead of print]

PMID:
29362222
13.

Fluorometric Sniff-Cam (Gas-Imaging System) Utilizing Alcohol Dehydrogenase for Imaging Concentration Distribution of Acetaldehyde in Breath and Transdermal Vapor after Drinking.

Iitani K, Sato T, Naisierding M, Hayakawa Y, Toma K, Arakawa T, Mitsubayashi K.

Anal Chem. 2018 Feb 20;90(4):2678-2685. doi: 10.1021/acs.analchem.7b04474. Epub 2018 Feb 6.

PMID:
29359564
14.

Optimized universal protocol for electroporation of both coagulase-positive and -negative Staphylococci.

Sato'o Y, Aiba Y, Kiga K, Watanabe S, Sasahara T, Hayakawa Y, Cui L.

J Microbiol Methods. 2018 Mar;146:25-32. doi: 10.1016/j.mimet.2018.01.006. Epub 2018 Feb 3.

PMID:
29355575
15.

Prodigiosin R2, a new prodigiosin from the roseophilin producer Streptomyces griseoviridis 2464-S5.

Kimata S, Matsuda T, Suizu Y, Hayakawa Y.

J Antibiot (Tokyo). 2018 Mar;71(3):393-396. doi: 10.1038/s41429-017-0011-1. Epub 2018 Jan 18.

PMID:
29348526
16.

Mature gastric chief cells are not required for the development of metaplasia.

Kinoshita H, Hayakawa Y, Niu Z, Konishi M, Hata M, Tsuboi M, Hayata Y, Hikiba Y, Ihara S, Nakagawa H, Hirata Y, Wang TC, Koike K.

Am J Physiol Gastrointest Liver Physiol. 2018 Jan 18. doi: 10.1152/ajpgi.00351.2017. [Epub ahead of print]

PMID:
29345968
17.

CXCR4-expressing Mist1+ progenitors in the gastric antrum contribute to gastric cancer development.

Sakitani K, Hayakawa Y, Deng H, Ariyama H, Kinoshita H, Konishi M, Ono S, Suzuki N, Ihara S, Niu Z, Kim W, Tanaka T, Liu H, Chen X, Tailor Y, Fox JG, Konieczny SF, Onodera H, Sepulveda AR, Asfaha S, Hirata Y, Worthley DL, Koike K, Wang TC.

Oncotarget. 2017 Nov 10;8(67):111012-111025. doi: 10.18632/oncotarget.22451. eCollection 2017 Dec 19.

18.

Correction to Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2018 Feb 8;61(3):1380. doi: 10.1021/acs.jmedchem.7b01911. Epub 2018 Jan 11. No abstract available.

PMID:
29323483
19.

Predictive factors of biochemical recurrence after radical prostatectomy for high-risk prostate cancer.

Murata Y, Tatsugami K, Yoshikawa M, Hamaguchi M, Yamada S, Hayakawa Y, Ueda K, Momosaki S, Sakamoto N.

Int J Urol. 2018 Mar;25(3):284-289. doi: 10.1111/iju.13514. Epub 2018 Jan 8.

PMID:
29315854
20.

Identification of essential biosynthetic genes and a true biosynthetic product for thioviridamide.

Izawa M, Nagamine S, Aoki H, Hayakawa Y.

J Gen Appl Microbiol. 2018 Mar 27;64(1):50-53. doi: 10.2323/jgam.2017.05.002. Epub 2017 Dec 30. No abstract available.

21.

The Dark Side of IFN-γ: Its Role in Promoting Cancer Immunoevasion.

Mojic M, Takeda K, Hayakawa Y.

Int J Mol Sci. 2017 Dec 28;19(1). pii: E89. doi: 10.3390/ijms19010089. Review.

22.

Long-term proton pump inhibitor use is a risk factor of gastric cancer after treatment for Helicobacter pylori: a retrospective cohort analysis.

Niikura R, Hayakawa Y, Hirata Y, Yamada A, Fujishiro M, Koike K.

Gut. 2017 Dec 22. pii: gutjnl-2017-315710. doi: 10.1136/gutjnl-2017-315710. [Epub ahead of print] No abstract available.

PMID:
29273641
23.

Impact of a novel biomarker, T-LAK cell-originating protein kinase (TOPK) expression on outcome in malignant glioma.

Hayashi T, Hayakawa Y, Koh M, Tomita T, Nagai S, Kashiwazaki D, Sugimori M, Origasa H, Kuroda S.

Neuropathology. 2018 Apr;38(2):144-153. doi: 10.1111/neup.12446. Epub 2017 Dec 21.

PMID:
29271010
24.

β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.

Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC.

Cancer Cell. 2018 Jan 8;33(1):75-90.e7. doi: 10.1016/j.ccell.2017.11.007. Epub 2017 Dec 14.

PMID:
29249692
25.

Comparative study of ipsilesional and contralesional repetitive transcranial magnetic stimulations for acute infarction.

Watanabe K, Kudo Y, Sugawara E, Nakamizo T, Amari K, Takahashi K, Tanaka O, Endo M, Hayakawa Y, Johkura K.

J Neurol Sci. 2018 Jan 15;384:10-14. doi: 10.1016/j.jns.2017.11.001. Epub 2017 Nov 9.

PMID:
29249365
26.

Cytokine signaling through Drosophila Mthl10 ties lifespan to environmental stress.

Sung EJ, Ryuda M, Matsumoto H, Uryu O, Ochiai M, Cook ME, Yi NY, Wang H, Putney JW, Bird GS, Shears SB, Hayakawa Y.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13786-13791. doi: 10.1073/pnas.1712453115. Epub 2017 Dec 11.

PMID:
29229844
27.

Excessively low salt diet damages the heart through activation of cardiac (pro) renin receptor, renin-angiotensin-aldosterone, and sympatho-adrenal systems in spontaneously hypertensive rats.

Okamoto C, Hayakawa Y, Aoyama T, Komaki H, Minatoguchi S, Iwasa M, Yamada Y, Kanamori H, Kawasaki M, Nishigaki K, Mikami A, Minatoguchi S.

PLoS One. 2017 Dec 8;12(12):e0189099. doi: 10.1371/journal.pone.0189099. eCollection 2017.

28.

A gene-driven recovery mechanism: Drosophila larvae increase feeding activity for post-stress weight recovery.

Ryuda M, Tabuchi M, Matsumoto H, Matsumura T, Ochiai M, Hayakawa Y.

Arch Insect Biochem Physiol. 2018 Mar;97(3). doi: 10.1002/arch.21440. Epub 2017 Dec 8.

PMID:
29218733
29.

Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop.

Chen X, Deng H, Churchill MJ, Luchsinger LL, Du X, Chu TH, Friedman RA, Middelhoff M, Ding H, Tailor YH, Wang ALE, Liu H, Niu Z, Wang H, Jiang Z, Renders S, Ho SH, Shah SV, Tishchenko P, Chang W, Swayne TC, Munteanu L, Califano A, Takahashi R, Nagar KK, Renz BW, Worthley DL, Westphalen CB, Hayakawa Y, Asfaha S, Borot F, Lin CS, Snoeck HW, Mukherjee S, Wang TC.

Cell Stem Cell. 2017 Dec 7;21(6):747-760.e7. doi: 10.1016/j.stem.2017.11.003. Epub 2017 Nov 30.

PMID:
29198940
30.

Involvement of laccase2 and yellow-e genes in antifungal host defense of the model beetle, Tribolium castaneum.

Hayakawa Y, Sawada M, Seki M, Sirasoonthorn P, Shiga S, Kamiya K, Minakuchi C, Miura K.

J Invertebr Pathol. 2018 Jan;151:41-49. doi: 10.1016/j.jip.2017.10.010. Epub 2017 Nov 2.

PMID:
29102780
31.

Nerves switch on angiogenic metabolism.

Hayakawa Y, Wang TC.

Science. 2017 Oct 20;358(6361):305-306. doi: 10.1126/science.aaq0365. No abstract available.

PMID:
29051365
32.

Synthesis of Potent and Selective Inhibitors of Aldo-Keto Reductase 1B10 and Their Efficacy against Proliferation, Metastasis, and Cisplatin Resistance of Lung Cancer Cells.

Endo S, Xia S, Suyama M, Morikawa Y, Oguri H, Hu D, Ao Y, Takahara S, Horino Y, Hayakawa Y, Watanabe Y, Gouda H, Hara A, Kuwata K, Toyooka N, Matsunaga T, Ikari A.

J Med Chem. 2017 Oct 26;60(20):8441-8455. doi: 10.1021/acs.jmedchem.7b00830. Epub 2017 Oct 13.

PMID:
28976752
33.

Colonoscopy reduces colorectal cancer mortality: A multicenter, long-term, colonoscopy-based cohort study.

Niikura R, Hirata Y, Suzuki N, Yamada A, Hayakawa Y, Suzuki H, Yamamoto S, Nakata R, Komatsu J, Okamoto M, Kodaira M, Shinozaki T, Fujishiro M, Watanabe T, Koike K.

PLoS One. 2017 Sep 28;12(9):e0185294. doi: 10.1371/journal.pone.0185294. eCollection 2017.

34.

Metaplasia in the Stomach-Precursor of Gastric Cancer?

Kinoshita H, Hayakawa Y, Koike K.

Int J Mol Sci. 2017 Sep 27;18(10). pii: E2063. doi: 10.3390/ijms18102063. Review.

35.

Heat stress hardening of oriental armyworms is induced by a transient elevation of reactive oxygen species during sublethal stress.

Matsumura T, Matsumoto H, Hayakawa Y.

Arch Insect Biochem Physiol. 2017 Nov;96(3). doi: 10.1002/arch.21421. Epub 2017 Sep 5.

PMID:
28872705
36.

Mechanism of secondary recrystallization of Goss grains in grain-oriented electrical steel.

Hayakawa Y.

Sci Technol Adv Mater. 2017 Jul 14;18(1):480-497. doi: 10.1080/14686996.2017.1341277. eCollection 2017.

37.

Development of a split-flow system for high precision variable sample introduction in supercritical fluid chromatography.

Sakai M, Hayakawa Y, Funada Y, Ando T, Fukusaki E, Bamba T.

J Chromatogr A. 2017 Sep 15;1515:218-231. doi: 10.1016/j.chroma.2017.07.077. Epub 2017 Jul 25.

PMID:
28802523
38.

Detection of residual metastatic tumor in the brain following Gamma Knife radiosurgery using a single or a series of magnetic resonance imaging scans: An autopsy study.

Sakuramachi M, Igaki H, Ikemura M, Yamashita H, Okuma K, Sekiya N, Hayakawa Y, Sakumi A, Takahashi W, Hasegawa H, Fukayama M, Nakagawa K.

Oncol Lett. 2017 Aug;14(2):2033-2040. doi: 10.3892/ol.2017.6359. Epub 2017 Jun 9.

39.

Fluorometric gas-imaging system (sniff-cam), using the extinction of NADH with an ADH reverse reaction, for acetaldehyde in the gas phase.

Iitani K, Sato T, Naisierding M, Hayakawa Y, Toma K, Arakawa T, Mitsubayashi K.

Analyst. 2017 Oct 9;142(20):3830-3836. doi: 10.1039/c7an00524e.

PMID:
28758645
40.

ASK1 facilitates tumor metastasis through phosphorylation of an ADP receptor P2Y12 in platelets.

Kamiyama M, Shirai T, Tamura S, Suzuki-Inoue K, Ehata S, Takahashi K, Miyazono K, Hayakawa Y, Sato T, Takeda K, Naguro I, Ichijo H.

Cell Death Differ. 2017 Dec;24(12):2066-2076. doi: 10.1038/cdd.2017.114. Epub 2017 Jul 28.

PMID:
28753204
41.

Investigation of directionally solidified InGaSb ternary alloys from Ga and Sb faces of GaSb(111) under prolonged microgravity at the International Space Station.

Nirmal Kumar V, Arivanandhan M, Rajesh G, Koyama T, Momose Y, Sakata K, Ozawa T, Okano Y, Inatomi Y, Hayakawa Y.

NPJ Microgravity. 2016 Jul 21;2:16026. doi: 10.1038/npjmgrav.2016.26. eCollection 2016.

42.

Dclk1-expressing tuft cells: critical modulators of the intestinal niche?

Middelhoff M, Westphalen CB, Hayakawa Y, Yan KS, Gershon MD, Wang TC, Quante M.

Am J Physiol Gastrointest Liver Physiol. 2017 Oct 1;313(4):G285-G299. doi: 10.1152/ajpgi.00073.2017. Epub 2017 Jul 6. Review.

PMID:
28684459
43.

Importance of optimizing chromatographic conditions and mass spectrometric parameters for supercritical fluid chromatography/mass spectrometry.

Fujito Y, Hayakawa Y, Izumi Y, Bamba T.

J Chromatogr A. 2017 Jul 28;1508:138-147. doi: 10.1016/j.chroma.2017.05.071. Epub 2017 Jun 2.

PMID:
28624150
44.

Prevalence of pks-positive Escherichia coli in Japanese patients with or without colorectal cancer.

Shimpoh T, Hirata Y, Ihara S, Suzuki N, Kinoshita H, Hayakawa Y, Ota Y, Narita A, Yoshida S, Yamada A, Koike K.

Gut Pathog. 2017 Jun 12;9:35. doi: 10.1186/s13099-017-0185-x. eCollection 2017.

45.

A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance.

Spechler SJ, Merchant JL, Wang TC, Chandrasoma P, Fox JG, Genta RM, Goldenring JR, Hayakawa Y, Kuipers EJ, Lund PK, McKeon F, Mills JC, Odze RD, Peek RM Jr., Pham T, Que J, Rustgi AK, Shaheen NJ, Shivdasani RA, Souza RF, Storz P, Todisco A, Wang DH, Wright NA.

Gastroenterology. 2017 Jul;153(1):e6-e13. doi: 10.1053/j.gastro.2017.05.050. Epub 2017 Jun 3. No abstract available.

46.

Coptidis Rhizoma induces intrinsic apoptosis through BAX and BAK activation in human melanoma.

Xu X, Yokoyama S, Hayakawa Y, Saiki I.

Oncol Rep. 2017 Jul;38(1):538-544. doi: 10.3892/or.2017.5672. Epub 2017 May 26.

PMID:
28560413
47.

Isthmus Stem Cells Are the Origins of Metaplasia in the Gastric Corpus.

Hayakawa Y, Fox JG, Wang TC.

Cell Mol Gastroenterol Hepatol. 2017 Mar 6;4(1):89-94. doi: 10.1016/j.jcmgh.2017.02.009. eCollection 2017 Jul.

48.
49.

Isthmus Progenitors, Not Chief Cells, Are the Likely Origin of Metaplasia in eR1-CreERT; LSL-KrasG12D Mice.

Hayakawa Y, Wang TC.

Gastroenterology. 2017 Jun;152(8):2078-2079. doi: 10.1053/j.gastro.2017.02.043. Epub 2017 May 4. No abstract available.

PMID:
28478152
50.

The Origins of Gastric Cancer From Gastric Stem Cells: Lessons From Mouse Models.

Hayakawa Y, Fox JG, Wang TC.

Cell Mol Gastroenterol Hepatol. 2017 Feb 20;3(3):331-338. doi: 10.1016/j.jcmgh.2017.01.013. eCollection 2017 May. Review.

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