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Genomic predictions combining SNP markers and copy number variations in Nellore cattle.

Hay EHA, Utsunomiya YT, Xu L, Zhou Y, Neves HHR, Carvalheiro R, Bickhart DM, Ma L, Garcia JF, Liu GE.

BMC Genomics. 2018 Jun 5;19(1):441. doi: 10.1186/s12864-018-4787-6.


Clinical diagnostic model for sciatica developed in primary care patients with low back-related leg pain.

Stynes S, Konstantinou K, Ogollah R, Hay EM, Dunn KM.

PLoS One. 2018 Apr 5;13(4):e0191852. doi: 10.1371/journal.pone.0191852. eCollection 2018.


Cost-utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: results from the POST Trial.

Kigozi J, Jowett S, Nicholl BI, Lewis M, Bartlam B, Green D, Belcher J, Clarkson K, Lingard Z, Pope C, Chew-Graham CA, Croft P, Hay EM, Peat G, Mallen CD.

Arthritis Care Res (Hoboken). 2018 Apr 2. doi: 10.1002/acr.23568. [Epub ahead of print]


Cost-effectiveness of a model consultation to support self-management in patients with osteoarthritis.

Oppong R, Jowett S, Lewis M, Clarkson K, Paskins Z, Croft P, Edwards JJ, Healey E, Jordan KP, Morden A, Ong BN, Porcheret M, Finney A, Hay E, Dziedzic K.

Rheumatology (Oxford). 2018 Jun 1;57(6):1056-1063. doi: 10.1093/rheumatology/key037.


Using an internet intervention to support self-management of low back pain in primary care: findings from a randomised controlled feasibility trial (SupportBack).

Geraghty AWA, Stanford R, Stuart B, Little P, Roberts LC, Foster NE, Hill JC, Hay EM, Turner D, Malakan W, Leigh L, Yardley L.

BMJ Open. 2018 Mar 9;8(3):e016768. doi: 10.1136/bmjopen-2017-016768.


Clinical course and prognostic factors across different musculoskeletal pain sites: A secondary analysis of individual patient data from randomised clinical trials.

Green DJ, Lewis M, Mansell G, Artus M, Dziedzic KS, Hay EM, Foster NE, van der Windt DA.

Eur J Pain. 2018 Jul;22(6):1057-1070. doi: 10.1002/ejp.1190. Epub 2018 Feb 22.


Novel approach to characterising individuals with low back-related leg pain: cluster identification with latent class analysis and 12-month follow-up.

Stynes S, Konstantinou K, Ogollah R, Hay EM, Dunn KM.

Pain. 2018 Apr;159(4):728-738. doi: 10.1097/j.pain.0000000000001147.


Fast genomic prediction of breeding values using parallel Markov chain Monte Carlo with convergence diagnosis.

Guo P, Zhu B, Niu H, Wang Z, Liang Y, Chen Y, Zhang L, Ni H, Guo Y, Hay EHA, Gao X, Gao H, Wu X, Xu L, Li J.

BMC Bioinformatics. 2018 Jan 3;19(1):3. doi: 10.1186/s12859-017-2003-3.


Genomic prediction of continuous and binary fertility traits of females in a composite beef cattle breed.

Toghiani S, Hay E, Sumreddee P, Geary TW, Rekaya R, Roberts AJ.

J Anim Sci. 2017 Nov;95(11):4787-4795. doi: 10.2527/jas2017.1944.


The feasibility and acceptability of a physical activity intervention for older people with chronic musculoskeletal pain: The iPOPP pilot trial protocol.

Healey EL, Jinks C, Foster NE, Chew-Graham CA, Pincus T, Hartshorne L, Cooke K, Nicholls E, Proctor J, Lewis M, Dent S, Wathall S, Hay EM, McBeth J.

Musculoskeletal Care. 2018 Mar;16(1):118-132. doi: 10.1002/msc.1222. Epub 2017 Dec 8.


Prognosis of sciatica and back-related leg pain in primary care: the ATLAS cohort.

Konstantinou K, Dunn KM, Ogollah R, Lewis M, van der Windt D, Hay EM; ATLAS Study Team.

Spine J. 2018 Jun;18(6):1030-1040. doi: 10.1016/j.spinee.2017.10.071. Epub 2017 Nov 21.


Subcutaneous Injection of Adalimumab Trial compared with Control (SCIATiC): a randomised controlled trial of adalimumab injection compared with placebo for patients receiving physiotherapy treatment for sciatica.

Williams NH, Jenkins A, Goulden N, Hoare Z, Hughes DA, Wood E, Foster NE, Walsh DA, Carnes D, Sparkes V, Hay EM, Isaacs J, Konstantinou K, Morrissey D, Karppinen J, Genevay S, Wilkinson C.

Health Technol Assess. 2017 Oct;21(60):1-180. doi: 10.3310/hta21600.


Implementing core NICE guidelines for osteoarthritis in primary care with a model consultation (MOSAICS): a cluster randomised controlled trial.

Dziedzic KS, Healey EL, Porcheret M, Afolabi EK, Lewis M, Morden A, Jinks C, McHugh GA, Ryan S, Finney A, Main C, Edwards JJ, Paskins Z, Pushpa-Rajah A, Hay EM.

Osteoarthritis Cartilage. 2018 Jan;26(1):43-53. doi: 10.1016/j.joca.2017.09.010. Epub 2017 Oct 14.


Genotype by environment interaction effects in genetic evaluation of preweaning gain for Line 1 Hereford cattle from Miles City, Montana.

MacNeil MD, Cardoso FF, Hay E.

J Anim Sci. 2017 Sep;95(9):3833-3838. doi: 10.2527/jas2017.1829.


Effectiveness and costs of a vocational advice service to improve work outcomes in patients with musculoskeletal pain in primary care: a cluster randomised trial (SWAP trial ISRCTN 52269669).

Wynne-Jones G, Artus M, Bishop A, Lawton SA, Lewis M, Jowett S, Kigozi J, Main C, Sowden G, Wathall S, Burton AK, van der Windt DA, Hay EM, Foster NE; SWAP Study Team.

Pain. 2017 Oct 30. doi: 10.1097/j.pain.0000000000001075. [Epub ahead of print]


Passive and Active Microrheology of the Intestinal Fluid of the Larval Zebrafish.

Taormina MJ, Hay EA, Parthasarathy R.

Biophys J. 2017 Aug 22;113(4):957-965. doi: 10.1016/j.bpj.2017.06.069.


Osteoblastic heparan sulfate glycosaminoglycans control bone remodeling by regulating Wnt signaling and the crosstalk between bone surface and marrow cells.

Mansouri R, Jouan Y, Hay E, Blin-Wakkach C, Frain M, Ostertag A, Le Henaff C, Marty C, Geoffroy V, Marie PJ, Cohen-Solal M, Modrowski D.

Cell Death Dis. 2017 Jun 29;8(6):e2902. doi: 10.1038/cddis.2017.287.


CNV Analysis of Host Responses to Porcine Reproductive and Respiratory Syndrome Virus Infection.

Hay EHA, Choi I, Xu L, Zhou Y, Rowland RRR, Lunney JK, Liu GE.

J Genomics. 2017 May 24;5:58-63. doi: 10.7150/jgen.20358. eCollection 2017.


Effect of a model consultation informed by guidelines on recorded quality of care of osteoarthritis (MOSAICS): a cluster randomised controlled trial in primary care.

Jordan KP, Edwards JJ, Porcheret M, Healey EL, Jinks C, Bedson J, Clarkson K, Hay EM, Dziedzic KS.

Osteoarthritis Cartilage. 2017 Oct;25(10):1588-1597. doi: 10.1016/j.joca.2017.05.017. Epub 2017 Jun 4.


The clinical and cost-effectiveness of stratified care for patients with sciatica: the SCOPiC randomised controlled trial protocol (ISRCTN75449581).

Foster NE, Konstantinou K, Lewis M, Ogollah R, Dunn KM, van der Windt D, Beardmore R, Artus M, Bartlam B, Hill JC, Jowett S, Kigozi J, Mallen C, Saunders B, Hay EM.

BMC Musculoskelet Disord. 2017 Apr 26;18(1):172. doi: 10.1186/s12891-017-1513-5.


The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

Mallen CD, Nicholl BI, Lewis M, Bartlam B, Green D, Jowett S, Kigozi J, Belcher J, Clarkson K, Lingard Z, Pope C, Chew-Graham CA, Croft P, Hay EM, Peat G.

PLoS Med. 2017 Apr 11;14(4):e1002273. doi: 10.1371/journal.pmed.1002273. eCollection 2017 Apr.


STEMS pilot trial: a pilot cluster randomised controlled trial to investigate the addition of patient direct access to physiotherapy to usual GP-led primary care for adults with musculoskeletal pain.

Bishop A, Ogollah RO, Jowett S, Kigozi J, Tooth S, Protheroe J, Hay EM, Salisbury C, Foster NE; STEMS study team.

BMJ Open. 2017 Mar 12;7(3):e012987. doi: 10.1136/bmjopen-2016-012987.


Multiregional integration in the brain during resting-state fMRI activity.

Hay E, Ritter P, Lobaugh NJ, McIntosh AR.

PLoS Comput Biol. 2017 Mar 1;13(3):e1005410. doi: 10.1371/journal.pcbi.1005410. eCollection 2017 Mar.


Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation.

Hay EA, Knowles C, Kolb A, MacKenzie A.

Neuropeptides. 2017 Aug;64:19-25. doi: 10.1016/j.npep.2016.11.010. Epub 2016 Dec 3. Review.


Dmp1 Promoter-Driven Diphtheria Toxin Receptor Transgene Expression Directs Unforeseen Effects in Multiple Tissues.

Al-Jazzar A, Javaheri B, Prideaux M, Boyde A, Scudamore CL, Cherifi C, Hay E, Hopkinson M, Boyd M, Cohen-Solal M, Farquharson C, Pitsillides AA.

Int J Mol Sci. 2016 Dec 26;18(1). pii: E29. doi: 10.3390/ijms18010029.


A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways.

Stoney PN, Rodrigues D, Helfer G, Khatib T, Ashton A, Hay EA, Starr R, Kociszewska D, Morgan P, McCaffery P.

Brain Behav Immun. 2017 Mar;61:340-352. doi: 10.1016/j.bbi.2016.12.013. Epub 2016 Dec 18.


Analysis of binary responses with outcome-specific misclassification probability in genome-wide association studies.

Rekaya R, Smith S, Hay EH, Farhat N, Aggrey SE.

Appl Clin Genet. 2016 Nov 30;9:169-177. eCollection 2016.


An analysis of possible off target effects following CAS9/CRISPR targeted deletions of neuropeptide gene enhancers from the mouse genome.

Hay EA, Khalaf AR, Marini P, Brown A, Heath K, Sheppard D, MacKenzie A.

Neuropeptides. 2017 Aug;64:101-107. doi: 10.1016/j.npep.2016.11.003. Epub 2016 Nov 4.


Systemic inhibition of IL-6/Stat3 signalling protects against experimental osteoarthritis.

Latourte A, Cherifi C, Maillet J, Ea HK, Bouaziz W, Funck-Brentano T, Cohen-Solal M, Hay E, Richette P.

Ann Rheum Dis. 2017 Apr;76(4):748-755. doi: 10.1136/annrheumdis-2016-209757. Epub 2016 Oct 27.


Keele Aches and Pains Study protocol: validity, acceptability, and feasibility of the Keele STarT MSK tool for subgrouping musculoskeletal patients in primary care.

Campbell P, Hill JC, Protheroe J, Afolabi EK, Lewis M, Beardmore R, Hay EM, Mallen CD, Bartlam B, Saunders B, van der Windt DA, Jowett S, Foster NE, Dunn KM.

J Pain Res. 2016 Oct 14;9:807-818. eCollection 2016.


Intradermal grass pollen immunotherapy increases TH2 and IgE responses and worsens respiratory allergic symptoms.

Slovick A, Douiri A, Muir R, Guerra A, Tsioulos K, Hay E, Lam EPS, Kelly J, Peacock JL, Ying S, Shamji MH, Cousins DJ, Durham SR, Till SJ.

J Allergy Clin Immunol. 2017 Jun;139(6):1830-1839.e13. doi: 10.1016/j.jaci.2016.09.024. Epub 2016 Oct 20.


Sclerostin and Bone Aging: A Mini-Review.

Hay E, Bouaziz W, Funck-Brentano T, Cohen-Solal M.

Gerontology. 2016;62(6):618-623. Epub 2016 May 14. Review.


Reconsultation, self-reported health status and costs following treatment at a musculoskeletal Clinical Assessment and Treatment Service (CATS): a 12-month prospective cohort study.

Roddy E, Jordan KP, Oppong R, Chen Y, Jowett S, Dawes P, Hider SL, Packham J, Stevenson K, Zwierska I, Hay EM.

BMJ Open. 2016 Oct 12;6(10):e011735. doi: 10.1136/bmjopen-2016-011735.


The clinical and cost effectiveness of steroid injection compared with night splints for carpal tunnel syndrome: the INSTINCTS randomised clinical trial study protocol.

Chesterton LS, Dziedzic KS, van der Windt DA, Davenport G, Myers HL, Rathod T, Blagojevic-Bucknall M, Jowet SM, Burton C, Roddy E, Hay EM.

BMC Musculoskelet Disord. 2016 Oct 6;17(1):415.


Reduced representation bisulphite sequencing of ten bovine somatic tissues reveals DNA methylation patterns and their impacts on gene expression.

Zhou Y, Xu L, Bickhart DM, Abdel Hay EH, Schroeder SG, Connor EE, Alexander LJ, Sonstegard TS, Van Tassell CP, Chen H, Liu GE.

BMC Genomics. 2016 Oct 6;17(1):779.


Managing back pain and osteoarthritis without paracetamol: Physical treatments are the way forward.

Mallen C, Hay E.

Br J Sports Med. 2016 Oct;50(20):1286-1287. doi: 10.1136/bjsports-2015-h1352rep. No abstract available.


Development and initial cohort validation of the Arthritis Research UK Musculoskeletal Health Questionnaire (MSK-HQ) for use across musculoskeletal care pathways.

Hill JC, Kang S, Benedetto E, Myers H, Blackburn S, Smith S, Dunn KM, Hay E, Rees J, Beard D, Glyn-Jones S, Barker K, Ellis B, Fitzpatrick R, Price A.

BMJ Open. 2016 Aug 5;6(8):e012331. doi: 10.1136/bmjopen-2016-012331.


A Longitudinal Study of Predictors of Housing Stability, Housing Quality, and Mental Health Functioning Among Single Homeless Individuals Staying in Emergency Shelters.

Aubry T, Duhoux A, Klodawsky F, Ecker J, Hay E.

Am J Community Psychol. 2016 Sep;58(1-2):123-35. doi: 10.1002/ajcp.12067. Epub 2016 Jul 30.


Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.

Bouaziz W, Sigaux J, Modrowski D, Devignes CS, Funck-Brentano T, Richette P, Ea HK, Provot S, Cohen-Solal M, Haÿ E.

Proc Natl Acad Sci U S A. 2016 May 10;113(19):5453-8. doi: 10.1073/pnas.1514854113. Epub 2016 Apr 27.


Role of ERαMISS in the Effect of Estradiol on Cancellous and Cortical Femoral Bone in Growing Female Mice

Vinel A, Hay E, Valera MC, Buscato M, Adlanmerini M, Guillaume M, Cohen-Solal M, Ohlsson C, Lenfant F, Arnal JF, Fontaine C.

Endocrinology. 2016 Jun;157(6):2533-44. doi: 10.1210/en.2015-1994. Epub 2016 Apr 22. Erratum in: Endocrinology. 2017 Nov 1;158(11):4122. Endocrinology. 2017 Mar 1;158(3):692.


Runx2 Controls Bone Resorption through the Down-Regulation of the Wnt Pathway in Osteoblasts.

Haxaire C, Haÿ E, Geoffroy V.

Am J Pathol. 2016 Jun;186(6):1598-609. doi: 10.1016/j.ajpath.2016.01.016. Epub 2016 Apr 12.


Reliability among clinicians diagnosing low back-related leg pain.

Stynes S, Konstantinou K, Dunn KM, Lewis M, Hay EM.

Eur Spine J. 2016 Sep;25(9):2734-40. doi: 10.1007/s00586-015-4359-2. Epub 2015 Dec 24.


Fates of imine intermediates in radical cyclizations of N-sulfonylindoles and ene-sulfonamides.

Zhang H, Hay EB, Geib SJ, Curran DP.

Beilstein J Org Chem. 2015 Sep 17;11:1649-55. doi: 10.3762/bjoc.11.181. eCollection 2015.


Characteristics of patients with low back and leg pain seeking treatment in primary care: baseline results from the ATLAS cohort study.

Konstantinou K, Dunn KM, Ogollah R, Vogel S, Hay EM; ATLAS study research team.

BMC Musculoskelet Disord. 2015 Nov 4;16:332. doi: 10.1186/s12891-015-0787-8.


Reconstruction and Simulation of Neocortical Microcircuitry.

Markram H, Muller E, Ramaswamy S, Reimann MW, Abdellah M, Sanchez CA, Ailamaki A, Alonso-Nanclares L, Antille N, Arsever S, Kahou GA, Berger TK, Bilgili A, Buncic N, Chalimourda A, Chindemi G, Courcol JD, Delalondre F, Delattre V, Druckmann S, Dumusc R, Dynes J, Eilemann S, Gal E, Gevaert ME, Ghobril JP, Gidon A, Graham JW, Gupta A, Haenel V, Hay E, Heinis T, Hernando JB, Hines M, Kanari L, Keller D, Kenyon J, Khazen G, Kim Y, King JG, Kisvarday Z, Kumbhar P, Lasserre S, Le Bé JV, Magalhães BR, Merchán-Pérez A, Meystre J, Morrice BR, Muller J, Muñoz-Céspedes A, Muralidhar S, Muthurasa K, Nachbaur D, Newton TH, Nolte M, Ovcharenko A, Palacios J, Pastor L, Perin R, Ranjan R, Riachi I, Rodríguez JR, Riquelme JL, Rössert C, Sfyrakis K, Shi Y, Shillcock JC, Silberberg G, Silva R, Tauheed F, Telefont M, Toledo-Rodriguez M, Tränkler T, Van Geit W, Díaz JV, Walker R, Wang Y, Zaninetta SM, DeFelipe J, Hill SL, Segev I, Schürmann F.

Cell. 2015 Oct 8;163(2):456-92. doi: 10.1016/j.cell.2015.09.029.


Using an internet intervention to support self-management of low back pain in primary care: protocol for a randomised controlled feasibility trial (SupportBack).

Geraghty AW, Stanford R, Little P, Roberts L, Foster NE, Hill JC, Hay E, Stuart B, Turner D, Yardley L.

BMJ Open. 2015 Sep 23;5(9):e009524. doi: 10.1136/bmjopen-2015-009524.


An Economic Evaluation of TENS in Addition to Usual Primary Care Management for the Treatment of Tennis Elbow: Results from the TATE Randomized Controlled Trial.

Lewis M, Chesterton LS, Sim J, Mallen CD, Hay EM, van der Windt DA.

PLoS One. 2015 Aug 28;10(8):e0135460. doi: 10.1371/journal.pone.0135460. eCollection 2015.


N-acetylcysteine treatment ameliorates the skeletal phenotype of a mouse model of diastrophic dysplasia.

Monti L, Paganini C, Lecci S, De Leonardis F, Hay E, Cohen-Solal M, Villani S, Superti-Furga A, Tenni R, Forlino A, Rossi A.

Hum Mol Genet. 2015 Oct 1;24(19):5570-80. doi: 10.1093/hmg/ddv289. Epub 2015 Jul 23.


A pilot cluster randomised controlled trial to investigate the addition of direct access to physiotherapy to usual GP-led primary care for adults with musculoskeletal pain: the STEMS pilot trial protocol (ISRCTN23378642).

Bishop A, Tooth S, Protheroe J, Salisbury C, Ogollah RO, Jowett S, Hay EM, Foster NE; STEMS study team.

Pilot Feasibility Stud. 2015 Jul 17;1:26. eCollection 2015.

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