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Items: 18


Quantitative Missense Variant Effect Prediction Using Large-Scale Mutagenesis Data.

Gray VE, Hause RJ, Luebeck J, Shendure J, Fowler DM.

Cell Syst. 2018 Jan 24;6(1):116-124.e3. doi: 10.1016/j.cels.2017.11.003. Epub 2017 Dec 6.


Corrigendum: Classification and characterization of microsatellite instability across 18 cancer types.

Hause RJ, Pritchard CC, Shendure J, Salipante SJ.

Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241a.


Identification of Novel Protein Expression Changes Following Cisplatin Treatment and Application to Combination Therapy.

Stark AL, Madian AG, Williams SW, Chen V, Wing C, Hause RJ Jr, To LA, Gill AL, Myers JL, Gorsic LK, Ciaccio MF, White KP, Jones RB, Dolan ME.

J Proteome Res. 2017 Nov 3;16(11):4227-4236. doi: 10.1021/acs.jproteome.7b00576. Epub 2017 Sep 29.


Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions.

Gray VE, Hause RJ, Fowler DM.

Genetics. 2017 Sep;207(1):53-61. doi: 10.1534/genetics.117.300064. Epub 2017 Jul 27.


Genetic Variants Contributing to Colistin Cytotoxicity: Identification of TGIF1 and HOXD10 Using a Population Genomics Approach.

Eadon MT, Hause RJ, Stark AL, Cheng YH, Wheeler HE, Burgess KS, Benson EA, Cunningham PN, Bacallao RL, Dagher PC, Skaar TC, Dolan ME.

Int J Mol Sci. 2017 Mar 18;18(3). pii: E661. doi: 10.3390/ijms18030661.


Classification and characterization of microsatellite instability across 18 cancer types.

Hause RJ, Pritchard CC, Shendure J, Salipante SJ.

Nat Med. 2016 Nov;22(11):1342-1350. doi: 10.1038/nm.4191. Epub 2016 Oct 3. Erratum in: Nat Med. 2017 Oct 6;23 (10 ):1241.


Mapping 3D genome architecture through in situ DNase Hi-C.

Ramani V, Cusanovich DA, Hause RJ, Ma W, Qiu R, Deng X, Blau CA, Disteche CM, Noble WS, Shendure J, Duan Z.

Nat Protoc. 2016 Nov;11(11):2104-21. doi: 10.1038/nprot.2016.126. Epub 2016 Sep 29.


Massively Parallel Functional Analysis of BRCA1 RING Domain Variants.

Starita LM, Young DL, Islam M, Kitzman JO, Gullingsrud J, Hause RJ, Fowler DM, Parvin JD, Shendure J, Fields S.

Genetics. 2015 Jun;200(2):413-22. doi: 10.1534/genetics.115.175802. Epub 2015 Mar 30. Erratum in: Genetics. 2017 Dec;207 (4):1713.


Genetic variation meets replication origins.

Hause RJ, Shendure J.

Cell. 2014 Nov 20;159(5):973-974. doi: 10.1016/j.cell.2014.11.009.


Saturation editing of genomic regions by multiplex homology-directed repair.

Findlay GM, Boyle EA, Hause RJ, Klein JC, Shendure J.

Nature. 2014 Sep 4;513(7516):120-3. doi: 10.1038/nature13695.


Identification and validation of genetic variants that influence transcription factor and cell signaling protein levels.

Hause RJ, Stark AL, Antao NN, Gorsic LK, Chung SH, Brown CD, Wong SS, Gill DF, Myers JL, To LA, White KP, Dolan ME, Jones RB.

Am J Hum Genet. 2014 Aug 7;95(2):194-208. doi: 10.1016/j.ajhg.2014.07.005. Epub 2014 Jul 31.


Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.

Leung KK, Hause RJ Jr, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB.

Mol Cell Proteomics. 2014 Jul;13(7):1705-23. doi: 10.1074/mcp.M113.034876. Epub 2014 Apr 12.


Protein quantitative trait loci identify novel candidates modulating cellular response to chemotherapy.

Stark AL, Hause RJ Jr, Gorsic LK, Antao NN, Wong SS, Chung SH, Gill DF, Im HK, Myers JL, White KP, Jones RB, Dolan ME.

PLoS Genet. 2014 Apr 3;10(4):e1004192. doi: 10.1371/journal.pgen.1004192. eCollection 2014 Apr.


Investigating models of protein function and allostery with a widespread mutational analysis of a light-activated protein.

Zayner JP, Antoniou C, French AR, Hause RJ Jr, Sosnick TR.

Biophys J. 2013 Aug 20;105(4):1027-36. doi: 10.1016/j.bpj.2013.07.010.


Comprehensive binary interaction mapping of SH2 domains via fluorescence polarization reveals novel functional diversification of ErbB receptors.

Hause RJ Jr, Leung KK, Barkinge JL, Ciaccio MF, Chuu CP, Jones RB.

PLoS One. 2012;7(9):e44471. doi: 10.1371/journal.pone.0044471. Epub 2012 Sep 4.


Caffeic acid phenethyl ester suppresses the proliferation of human prostate cancer cells through inhibition of p70S6K and Akt signaling networks.

Chuu CP, Lin HP, Ciaccio MF, Kokontis JM, Hause RJ Jr, Hiipakka RA, Liao S, Jones RB.

Cancer Prev Res (Phila). 2012 May;5(5):788-97. doi: 10.1158/1940-6207.CAPR-12-0004-T.


Natural Genetic Variation for Growth and Development Revealed by High-Throughput Phenotyping in Arabidopsis thaliana.

Zhang X, Hause RJ Jr, Borevitz JO.

G3 (Bethesda). 2012 Jan;2(1):29-34. doi: 10.1534/g3.111.001487. Epub 2012 Jan 1.


Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches.

Hause RJ, Kim HD, Leung KK, Jones RB.

Expert Rev Proteomics. 2011 Oct;8(5):565-75. doi: 10.1586/epr.11.49. Review.

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