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Items: 15

1.

(-)-(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol hydrochloride (tapentadol HCl): a novel mu-opioid receptor agonist/norepinephrine reuptake inhibitor with broad-spectrum analgesic properties.

Tzschentke TM, Christoph T, Kögel B, Schiene K, Hennies HH, Englberger W, Haurand M, Jahnel U, Cremers TI, Friderichs E, De Vry J.

J Pharmacol Exp Ther. 2007 Oct;323(1):265-76. Epub 2007 Jul 26.

2.

Diazabicyclononanones, a potent class of kappa opioid analgesics.

Holzgrabe U, Cambareri A, Kuhl U, Siener T, Brandt W, Strassburger W, Friderichs E, Englberger W, Kögel B, Haurand M.

Farmaco. 2002 Jul;57(7):531-4.

PMID:
12164207
3.

Synthesis and opioid receptor affinity of a series of 2, 4-diaryl-substituted 3,7-diazabicylononanones.

Siener T, Cambareri A, Kuhl U, Englberger W, Haurand M, Kögel B, Holzgrabe U.

J Med Chem. 2000 Oct 5;43(20):3746-51.

PMID:
11020289
4.

Diazabicyclo[3.3.1]nonanone-type ligands for the opioid receptors.

Kuhl U, Englberger W, Haurand M, Holzgrabe U.

Arch Pharm (Weinheim). 2000 Jul;333(7):226-30.

PMID:
10965597
5.

Affinity, potency and efficacy of tramadol and its metabolites at the cloned human mu-opioid receptor.

Gillen C, Haurand M, Kobelt DJ, Wnendt S.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Aug;362(2):116-21.

PMID:
10961373
6.

Influence of tramadol on neurotransmitter systems of the rat brain.

Frink MC, Hennies HH, Englberger W, Haurand M, Wilffert B.

Arzneimittelforschung. 1996 Nov;46(11):1029-36.

PMID:
8955860
7.

Search for the pharmacophore in kappa-agonistic diazabicyclo[3.3.1]nonan-9-one-1,5-diesters and arylacetamides.

Brandt W, Drosihn S, Haurand M, Holzgrabe U, Nachtsheim C.

Arch Pharm (Weinheim). 1996 Jun;329(6):311-23.

PMID:
8767114
8.

Involvement of calcium in the thimerosal-stimulated formation of leukotriene by fMLP in human polymorphonuclear leukocytes.

Hatzelmann A, Haurand M, Ullrich V.

Biochem Pharmacol. 1990 Feb 1;39(3):559-67.

PMID:
2154987
10.

Kinetic studies on arachidonate 5-lipoxygenase from rat basophilic leukemia cells.

Haurand M, Flohé L.

Biol Chem Hoppe Seyler. 1988 Feb;369(2):133-42.

PMID:
3365329
11.

Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: development of a novel enzyme assay.

Hecker M, Haurand M, Ullrich V, Diczfalusy U, Hammarström S.

Arch Biochem Biophys. 1987 Apr;254(1):124-35.

PMID:
3579292
12.

Spectral studies on structure-activity relationships of thromboxane synthase inhibitors.

Hecker M, Haurand M, Ullrich V, Terao S.

Eur J Biochem. 1986 May 15;157(1):217-23.

13.
14.

Fibrinogen distribution on surfaces and in organelles of ADP stimulated human blood platelets.

Morgenstern E, Edelmann L, Reimers HJ, Miyashita C, Haurand M.

Eur J Cell Biol. 1985 Sep;38(2):292-300.

PMID:
4043093
15.

Thromboxane synthase as a cytochrome P450 enzyme.

Ullrich V, Haurand M.

Adv Prostaglandin Thromboxane Leukot Res. 1983;11:105-10. No abstract available.

PMID:
6221511

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