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Items: 1 to 50 of 110

1.

Biorelevant Media Slows the Solution-Mediated Phase Transformation of Amorphous Spironolactone.

Kleppe MS, Haskell RJ, Bogner RH.

J Pharm Sci. 2018 Jan;107(1):426-435. doi: 10.1016/j.xphs.2017.10.041. Epub 2017 Nov 6.

PMID:
29122582
2.

Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance.

Chen H, Pui Y, Liu C, Chen Z, Su CC, Hageman M, Hussain M, Haskell R, Stefanski K, Foster K, Gudmundsson O, Qian F.

J Pharm Sci. 2018 Jan;107(1):317-326. doi: 10.1016/j.xphs.2017.10.028. Epub 2017 Oct 26.

PMID:
29107047
3.

A polychromatic turbidity microplate assay to distinguish discovery stage drug molecules with beneficial precipitation properties.

Morrison J, Nophsker M, Elzinga P, Donoso M, Park H, Haskell R.

Int J Pharm. 2017 Oct 5;531(1):24-34. doi: 10.1016/j.ijpharm.2017.07.086. Epub 2017 Aug 7.

PMID:
28797968
4.

Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery.

Morgen M, Saxena A, Chen XQ, Miller W, Nkansah R, Goodwin A, Cape J, Haskell R, Su C, Gudmundsson O, Hageman M, Kumar A, Chowan GS, Rao A, Holenarsipur VK.

Eur J Pharm Biopharm. 2017 Aug;117:212-223. doi: 10.1016/j.ejpb.2017.04.021. Epub 2017 Apr 21.

5.

Discovery of a Hepatitis C Virus NS5B Replicase Palm Site Allosteric Inhibitor (BMS-929075) Advanced to Phase 1 Clinical Studies.

Yeung KS, Beno BR, Parcella K, Bender JA, Grant-Young KA, Nickel A, Gunaga P, Anjanappa P, Bora RO, Selvakumar K, Rigat K, Wang YK, Liu M, Lemm J, Mosure K, Sheriff S, Wan C, Witmer M, Kish K, Hanumegowda U, Zhuo X, Shu YZ, Parker D, Haskell R, Ng A, Gao Q, Colston E, Raybon J, Grasela DM, Santone K, Gao M, Meanwell NA, Sinz M, Soars MG, Knipe JO, Roberts SB, Kadow JF.

J Med Chem. 2017 May 25;60(10):4369-4385. doi: 10.1021/acs.jmedchem.7b00328. Epub 2017 May 4.

PMID:
28430437
6.

Sodium Lauryl Sulfate Competitively Interacts with HPMC-AS and Consequently Reduces Oral Bioavailability of Posaconazole/HPMC-AS Amorphous Solid Dispersion.

Chen Y, Wang S, Wang S, Liu C, Su C, Hageman M, Hussain M, Haskell R, Stefanski K, Qian F.

Mol Pharm. 2016 Aug 1;13(8):2787-95. doi: 10.1021/acs.molpharmaceut.6b00391. Epub 2016 Jul 1.

PMID:
27337060
7.

Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity.

Regueiro-Ren A, Liu Z, Chen Y, Sin N, Sit SY, Swidorski JJ, Chen J, Venables BL, Zhu J, Nowicka-Sans B, Protack T, Lin Z, Terry B, Samanta H, Zhang S, Li Z, Beno BR, Huang XS, Rahematpura S, Parker DD, Haskell R, Jenkins S, Santone KS, Cockett MI, Krystal M, Meanwell NA, Hanumegowda U, Dicker IB.

ACS Med Chem Lett. 2016 Apr 22;7(6):568-72. doi: 10.1021/acsmedchemlett.6b00010. eCollection 2016 Jun 9.

8.

Initial Drug Dissolution from Amorphous Solid Dispersions Controlled by Polymer Dissolution and Drug-Polymer Interaction.

Chen Y, Wang S, Wang S, Liu C, Su C, Hageman M, Hussain M, Haskell R, Stefanski K, Qian F.

Pharm Res. 2016 Oct;33(10):2445-58. doi: 10.1007/s11095-016-1969-2. Epub 2016 Jun 9.

PMID:
27283830
9.

Service user and family member perspectives on services for mental health, substance use/addiction, and violence: a qualitative study of their goals, experiences and recommendations.

Haskell R, Graham K, Bernards S, Flynn A, Wells S.

Int J Ment Health Syst. 2016 Feb 20;10:9. doi: 10.1186/s13033-016-0040-3. eCollection 2016.

10.

Centrally Delivered BACE1 Inhibitor Activates Microglia, and Reverses Amyloid Pathology and Cognitive Deficit in Aged Tg2576 Mice.

Thakker DR, Sankaranarayanan S, Weatherspoon MR, Harrison J, Pierdomenico M, Heisel JM, Thompson LA, Haskell R, Grace JE, Taylor SJ, Albright CF, Shafer LL.

J Neurosci. 2015 Apr 29;35(17):6931-6. doi: 10.1523/JNEUROSCI.2262-14.2015.

11.

Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs.

Kleppe MS, Forney-Stevens KM, Haskell RJ, Bogner RH.

AAPS J. 2015 Jul;17(4):902-17. doi: 10.1208/s12248-015-9748-2. Epub 2015 Apr 8.

12.

Drug-polymer-water interaction and its implication for the dissolution performance of amorphous solid dispersions.

Chen Y, Liu C, Chen Z, Su C, Hageman M, Hussain M, Haskell R, Stefanski K, Qian F.

Mol Pharm. 2015 Feb 2;12(2):576-89. doi: 10.1021/mp500660m. Epub 2015 Jan 12.

PMID:
25535667
13.

A systematic evaluation of solubility enhancing excipients to enable the generation of permeability data for poorly soluble compounds in Caco-2 model.

Shah D, Paruchury S, Matta M, Chowan G, Subramanian M, Saxena A, Soars MG, Herbst J, Haskell R, Marathe P, Mandlekar S.

Drug Metab Lett. 2014;8(2):109-18.

PMID:
25429513
14.

A combination turbidity and supernatant microplate assay to rank-order the supersaturation limits of early drug candidates.

Morrison JS, Nophsker MJ, Haskell RJ.

J Pharm Sci. 2014 Oct;103(10):3022-32. doi: 10.1002/jps.24090. Epub 2014 Jul 28.

PMID:
25070886
15.

Design and synthesis of 4-heteroaryl 1,2,3,4-tetrahydroisoquinolines as triple reuptake inhibitors.

Liu S, Zha C, Nacro K, Hu M, Cui W, Yang YL, Bhatt U, Sambandam A, Isherwood M, Yet L, Herr MT, Ebeltoft S, Hassler C, Fleming L, Pechulis AD, Payen-Fornicola A, Holman N, Milanowski D, Cotterill I, Mozhaev V, Khmelnitsky Y, Guzzo PR, Sargent BJ, Molino BF, Olson R, King D, Lelas S, Li YW, Johnson K, Molski T, Orie A, Ng A, Haskell R, Clarke W, Bertekap R, O'Connell J, Lodge N, Sinz M, Adams S, Zaczek R, Macor JE.

ACS Med Chem Lett. 2014 May 13;5(7):760-5. doi: 10.1021/ml500053b. eCollection 2014 Jul 10.

16.

IFN-γ directly controls IL-33 protein level through a STAT1- and LMP2-dependent mechanism.

Kopach P, Lockatell V, Pickering EM, Haskell RE, Anderson RD, Hasday JD, Todd NW, Luzina IG, Atamas SP.

J Biol Chem. 2014 Apr 25;289(17):11829-43. doi: 10.1074/jbc.M113.534396. Epub 2014 Mar 11.

17.

Memory in aged mice is rescued by enhanced expression of the GluN2B subunit of the NMDA receptor.

Brim BL, Haskell R, Awedikian R, Ellinwood NM, Jin L, Kumar A, Foster TC, Magnusson KR.

Behav Brain Res. 2013 Feb 1;238:211-26. doi: 10.1016/j.bbr.2012.10.026. Epub 2012 Oct 24.

18.

Surfactant choice and the physical stability of nanosuspensions as a function of pH.

Donoso MD, Haskell RJ, Schartman RR.

Int J Pharm. 2012 Dec 15;439(1-2):1-7. doi: 10.1016/j.ijpharm.2012.09.012. Epub 2012 Sep 14.

PMID:
22982488
19.

Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity.

Blalock LT, Landsberg J, Messmer M, Shi J, Pardee AD, Haskell R, Vujanovic L, Kirkwood JM, Butterfield LH.

Oncoimmunology. 2012 May 1;1(3):287-357.

20.

Targeted delivery of a poorly water-soluble compound to hair follicles using polymeric nanoparticle suspensions.

Morgen M, Lu GW, Du D, Stehle R, Lembke F, Cervantes J, Ciotti S, Haskell R, Smithey D, Haley K, Fan C.

Int J Pharm. 2011 Sep 15;416(1):314-22. doi: 10.1016/j.ijpharm.2011.06.019. Epub 2011 Jun 21.

PMID:
21722722
21.

Effect of substrate composition and alignment on corneal cell phenotype.

Phu D, Wray LS, Warren RV, Haskell RC, Orwin EJ.

Tissue Eng Part A. 2011 Mar;17(5-6):799-807. doi: 10.1089/ten.TEA.2009.0724. Epub 2010 Dec 7.

22.

Use of sustainable chemistry to produce an acyl amino acid surfactant.

Reznik GO, Vishwanath P, Pynn MA, Sitnik JM, Todd JJ, Wu J, Jiang Y, Keenan BG, Castle AB, Haskell RF, Smith TF, Somasundaran P, Jarrell KA.

Appl Microbiol Biotechnol. 2010 May;86(5):1387-97. doi: 10.1007/s00253-009-2431-8. Epub 2010 Jan 23.

PMID:
20094712
23.

Terminology use in electronic health records: basic principles.

Watkins TJ, Haskell RE, Lundberg CB, Brokel JM, Wilson ML, Hardiker N.

Urol Nurs. 2009 Sep-Oct;29(5):321-6; quiz 327.

PMID:
19863039
24.

Structured terminologies in clinical information systems: implementation through collaboration.

Haskell RE, Hardiker NR, Watkins TJ, Lundberg CB, Brokel JM, Wilson ML.

Stud Health Technol Inform. 2009;146:659-62.

PMID:
19592923
25.

Translation and integration of CCC nursing diagnoses into ICNP.

Matney SA, DaDamio R, Couderc C, Dlugos M, Evans J, Gianonne G, Haskell R, Hardiker N, Coenen A, Saba VK.

J Am Med Inform Assoc. 2008 Nov-Dec;15(6):791-3. doi: 10.1197/jamia.M2801. Epub 2008 Aug 28.

26.

Optical coherence microscopy for the evaluation of a tissue-engineered artificial cornea.

Orwin EJ, Lee S, Raub C, Icenogle T, Arman M, Cho A, Lovec R, Malone A, Haskell RC, Hoeling BM, Petersen DC.

Conf Proc IEEE Eng Med Biol Soc. 2004;2:1218-21.

PMID:
17271907
27.

Immunogold labeling to enhance contrast in optical coherence microscopy of tissue engineered corneal constructs.

Raub CB, Orwin EJ, Haskell R.

Conf Proc IEEE Eng Med Biol Soc. 2004;2:1210-3.

PMID:
17271905
28.

Visualizing early frog development with motion-sensitive 3-D optical coherence microscopy.

Haskell RC, Williams ME, Petersen DC, Hoeling BM, Schile AJ, Pennington JD, Seetin MG, Castelaz JM, Fraser SE, Papan C, Ren H, de Boer JF, Chen Z.

Conf Proc IEEE Eng Med Biol Soc. 2004;7:5296-9.

PMID:
17271536
29.

Subclavian artery puncture repair with Angio-Seal deployment.

Micha JP, Goldstein BH, Lindsay SF, Haskell R, Oglevie S, Rettenmaier MA, Brown JV 3rd.

Gynecol Oncol. 2007 Mar;104(3):761-3. Epub 2006 Dec 12.

PMID:
17166569
30.

Role of beat noise in limiting the sensitivity of optical coherence tomography.

Haskell RC, Liao D, Pivonka AE, Bell TL, Haberle BR, Hoeling BM, Petersen DC.

J Opt Soc Am A Opt Image Sci Vis. 2006 Nov;23(11):2747-55.

PMID:
17047700
31.

Office-based optical coherence tomographic imaging of human vocal cords.

Guo S, Hutchison R, Jackson RP, Kohli A, Sharp T, Orwin E, Haskell R, Chen Z, Wong BJ.

J Biomed Opt. 2006 May-Jun;11(3):30501.

PMID:
16822047
32.

Application of a mixture experimental design in the optimization of a self-emulsifying formulation with a high drug load.

Gao P, Witt MJ, Haskell RJ, Zamora KM, Shifflett JR.

Pharm Dev Technol. 2004 Aug;9(3):301-9.

PMID:
15458235
33.

Modeling nursing interventions in the act class of HL7 RIM Version 3.

Danko A, Kennedy R, Haskell R, Androwich IM, Button P, Correia CM, Grobe SJ, Harris MR, Matney S, Russler D.

J Biomed Inform. 2003 Aug-Oct;36(4-5):294-303.

34.

Operational evaluation of pulse oximetry in NICU patients with arterial access.

Gerstmann D, Berg R, Haskell R, Brower C, Wood K, Yoder B, Greenway L, Lassen G, Ogden R, Stoddard R, Minton S.

J Perinatol. 2003 Jul-Aug;23(5):378-83.

35.

Viral-mediated delivery of the late-infantile neuronal ceroid lipofuscinosis gene, TPP-I to the mouse central nervous system.

Haskell RE, Hughes SM, Chiorini JA, Alisky JM, Davidson BL.

Gene Ther. 2003 Jan;10(1):34-42.

PMID:
12525835
36.

Adenovirus-mediated gene delivery to cells of the magnocellular hypothalamo-neurohypophyseal system.

Vasquez EC, Beltz TG, Haskell RE, Johnson RF, Meyrelles SS, Davidson BL, Johnson AK.

Exp Neurol. 2001 Feb;167(2):260-71.

PMID:
11161614
37.

Evaluation of the clinical LOINC (Logical Observation Identifiers, Names, and Codes) semantic structure as a terminology model for standardized assessment measures.

Bakken S, Cimino JJ, Haskell R, Kukafka R, Matsumoto C, Chan GK, Huff SM.

J Am Med Inform Assoc. 2000 Nov-Dec;7(6):529-38.

38.

Unsuspected child abuse revealed by delayed presentation of periportal tracking and myoglobinuria.

DiGiacomo JC, Frankel H, Haskell RM, Rotondo MF, Schwab CW.

J Trauma. 2000 Aug;49(2):348-50. No abstract available.

PMID:
10963553
39.

A simple method for the rapid generation of recombinant adenovirus vectors.

Anderson RD, Haskell RE, Xia H, Roessler BJ, Davidson BL.

Gene Ther. 2000 Jun;7(12):1034-8.

40.

Optical coherence microscopy. A technology for rapid, in vivo, non-destructive visualization of plants and plant cells.

Hettinger JW, de la Peña Mattozzi M, Myers WR, Williams ME, Reeves A, Parsons RL, Haskell RC, Petersen DC, Wang R, Medford JI.

Plant Physiol. 2000 May;123(1):3-16.

41.

Citation for the BAOMS Surgery Prize 1998--Mark McGurk.

Haskell R.

Br J Oral Maxillofac Surg. 2000 Feb;38(1):2. No abstract available.

PMID:
10783437
42.

Batten disease: evaluation of CLN3 mutations on protein localization and function.

Haskell RE, Carr CJ, Pearce DA, Bennett MJ, Davidson BL.

Hum Mol Genet. 2000 Mar 22;9(5):735-44.

PMID:
10749980
43.

An optical coherence microscope for 3-dimensional imaging in developmental biology.

Hoeling B, Fernandez A, Haskell R, Huang E, Myers W, Petersen D, Ungersma S, Wang R, Williams M, Fraser S.

Opt Express. 2000 Mar 27;6(7):136-46.

PMID:
19404345
44.

Primary seminal vesicle carcinoma: an immunohistochemical analysis of four cases.

Ormsby AH, Haskell R, Jones D, Goldblum JR.

Mod Pathol. 2000 Jan;13(1):46-51.

45.

Unconscious communication: communicative psychoanalysis and subliteral cognition.

Haskell RE.

J Am Acad Psychoanal. 1999 Fall;27(3):471-502. No abstract available.

PMID:
10615643
46.

Wisdom tooth removal and lingual nerve damage.

McGurk M, Haskell R.

Br J Oral Maxillofac Surg. 1999 Aug;37(4):253-4. Review. No abstract available.

PMID:
10475643
47.

Hypomagnesemia in trauma patients.

Frankel H, Haskell R, Lee SY, Miller D, Rotondo M, Schwab CW.

World J Surg. 1999 Sep;23(9):966-9.

PMID:
10449829
48.

Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo.

Stec DE, Davisson RL, Haskell RE, Davidson BL, Sigmund CD.

J Biol Chem. 1999 Jul 23;274(30):21285-90.

49.

Intracellular trafficking of the JNCL protein CLN3.

Haskell RE, Derksen TA, Davidson BL.

Mol Genet Metab. 1999 Apr;66(4):253-60.

PMID:
10191111
50.

Replication-deficient adenovirus vector transfer of gfp reporter gene into supraoptic nucleus and subfornical organ neurons.

Vasquez EC, Johnson RF, Beltz TG, Haskell RE, Davidson BL, Johnson AK.

Exp Neurol. 1998 Dec;154(2):353-65.

PMID:
9878173

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