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Items: 1 to 50 of 976

1.

GP leadership in clinical commissioning groups: a qualitative multi-case study approach across England.

Marshall M, Holti R, Hartley J, Matharu T, Storey J.

Br J Gen Pract. 2018 May 8. pii: bjgp18X696197. doi: 10.3399/bjgp18X696197. [Epub ahead of print]

PMID:
29739777
2.

A systematic review of risk of HIV transmission through biting or spitting: implications for policy.

Cresswell FV, Ellis J, Hartley J, Sabin CA, Orkin C, Churchill DR.

HIV Med. 2018 Apr 23. doi: 10.1111/hiv.12625. [Epub ahead of print]

PMID:
29687590
3.

Simultaneous neutron powder diffraction and microwave dielectric studies of ammonia absorption in metal-organic framework systems.

Barter M, Hartley J, Yazigi FJ, Marshall RJ, Forgan RS, Porch A, Jones MO.

Phys Chem Chem Phys. 2018 Apr 18;20(15):10460-10469. doi: 10.1039/c8cp00259b.

PMID:
29617020
4.

Design, synthesis, nuclear localization, and biological activity of a fluorescent duocarmycin analog, HxTfA.

Kiakos K, Englinger B, Yanow SK, Wernitznig D, Jakupec MA, Berger W, Keppler BK, Hartley JA, Lee M, Patil PC.

Bioorg Med Chem Lett. 2018 May 1;28(8):1342-1347. doi: 10.1016/j.bmcl.2018.03.016. Epub 2018 Mar 5.

PMID:
29548574
5.

Oophoropexy for Recurrent Ovarian Torsion.

Hartley J, Akhtar M, Edi-Osagie E.

Case Rep Obstet Gynecol. 2018 Feb 6;2018:8784958. doi: 10.1155/2018/8784958. eCollection 2018.

6.

MEK inhibition leads to BRCA2 downregulation and sensitization to DNA damaging agents in pancreas and ovarian cancer models.

Vena F, Jia R, Esfandiari A, Garcia-Gomez JJ, Rodriguez-Justo M, Ma J, Syed S, Crowley L, Elenbaas B, Goodstal S, Hartley JA, Hochhauser D.

Oncotarget. 2018 Jan 22;9(14):11592-11603. doi: 10.18632/oncotarget.24294. eCollection 2018 Feb 20.

7.

Clinical leadership in service redesign using Clinical Commissioning Groups: a mixed-methods study.

Storey J, Holti R, Hartley J, Marshall M, Matharu T.

Southampton (UK): NIHR Journals Library; 2018 Jan.

8.

ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.

Zammarchi F, Corbett S, Adams L, Tyrer PC, Kiakos K, Janghra N, Marafioti T, Britten CE, Havenith CEG, Chivers S, D'Hooge F, Williams DG, Tiberghien A, Howard PW, Hartley JA, van Berkel PH.

Blood. 2018 Mar 8;131(10):1094-1105. doi: 10.1182/blood-2017-10-813493. Epub 2018 Jan 3.

PMID:
29298756
9.

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Abbosh C, Birkbak NJ, Wilson GA, Jamal-Hanjani M, Constantin T, Salari R, Le Quesne J, Moore DA, Veeriah S, Rosenthal R, Marafioti T, Kirkizlar E, Watkins TBK, McGranahan N, Ward S, Martinson L, Riley J, Fraioli F, Al Bakir M, Grönroos E, Zambrana F, Endozo R, Bi WL, Fennessy FM, Sponer N, Johnson D, Laycock J, Shafi S, Czyzewska-Khan J, Rowan A, Chambers T, Matthews N, Turajlic S, Hiley C, Lee SM, Forster MD, Ahmad T, Falzon M, Borg E, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Hafez D, Naik A, Ganguly A, Kareht S, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Oukrif D, Akarca AU, Hartley JA, Lowe HL, Lock S, Iles N, Bell H, Ngai Y, Elgar G, Szallasi Z, Schwarz RF, Herrero J, Stewart A, Quezada SA, Peggs KS, Van Loo P, Dive C, Lin CJ, Rabinowitz M, Aerts HJWL, Hackshaw A, Shaw JA, Zimmermann BG, Swanton C.

Nature. 2018 Feb 8;554(7691):264. doi: 10.1038/nature25161. Epub 2017 Dec 20.

PMID:
29258292
10.

Successful aging: The role of cognitive gerontology.

Hartley A, Angel L, Castel A, Didierjean A, Geraci L, Hartley J, Hazeltine E, Lemaire P, Maquestiaux F, Ruthruff E, Taconnat L, Thevenot C, Touron D.

Exp Aging Res. 2018 Jan-Feb;44(1):82-93. doi: 10.1080/0361073X.2017.1398849. Epub 2017 Nov 21.

PMID:
29161195
11.

The adaptation and translation of the PEACH™ RCT intervention: the process and outcomes of the PEACH™ in the community trial.

Perry RA, Golley RK, Hartley J, Magarey AM.

Public Health. 2017 Dec;153:154-162. doi: 10.1016/j.puhe.2017.08.009. Epub 2017 Oct 26.

PMID:
29107197
12.

Voltammetric and spectroscopic study of ferrocene and hexacyanoferrate and the suitability of their redox couples as internal standards in ionic liquids.

Frenzel N, Hartley J, Frisch G.

Phys Chem Chem Phys. 2017 Nov 1;19(42):28841-28852. doi: 10.1039/c7cp05483a.

PMID:
29053161
13.

Evaluation of the selectivity and sensitivity of isoform- and mutation-specific RAS antibodies.

Waters AM, Ozkan-Dagliyan I, Vaseva AV, Fer N, Strathern LA, Hobbs GA, Tessier-Cloutier B, Gillette WK, Bagni R, Whiteley GR, Hartley JL, McCormick F, Cox AD, Houghton PJ, Huntsman DG, Philips MR, Der CJ.

Sci Signal. 2017 Sep 26;10(498). pii: eaao3332. doi: 10.1126/scisignal.aao3332.

14.

Quality of Local Excision for Rectal Neoplasms Using Transanal Endoscopic Microsurgery Versus Transanal Minimally Invasive Surgery: A Multi-institutional Matched Analysis.

Lee L, Edwards K, Hunter IA, Hartley JE, Atallah SB, Albert MR, Hill J, Monson JR.

Dis Colon Rectum. 2017 Sep;60(9):928-935. doi: 10.1097/DCR.0000000000000884.

PMID:
28796731
15.

Recombinant Origins of Pathogenic and Nonpathogenic Mouse Gammaretroviruses with Polytropic Host Range.

Bamunusinghe D, Liu Q, Plishka R, Dolan MA, Skorski M, Oler AJ, Yedavalli VRK, Buckler-White A, Hartley JW, Kozak CA.

J Virol. 2017 Oct 13;91(21). pii: e00855-17. doi: 10.1128/JVI.00855-17. Print 2017 Nov 1.

16.

Association of Coloproctology of Great Britain & Ireland (ACPGBI): Guidelines for the Management of Cancer of the Colon, Rectum and Anus (2017) - Follow Up, Lifestyle and Survivorship.

Leong K, Hartley J, Karandikar S.

Colorectal Dis. 2017 Jul;19 Suppl 1:67-70. doi: 10.1111/codi.13706. No abstract available.

PMID:
28632315
17.

The emerging role of anti-CD25 directed therapies as both immune modulators and targeted agents in cancer.

Flynn MJ, Hartley JA.

Br J Haematol. 2017 Oct;179(1):20-35. doi: 10.1111/bjh.14770. Epub 2017 May 30. Review.

PMID:
28556984
18.

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution.

Abbosh C, Birkbak NJ, Wilson GA, Jamal-Hanjani M, Constantin T, Salari R, Le Quesne J, Moore DA, Veeriah S, Rosenthal R, Marafioti T, Kirkizlar E, Watkins TBK, McGranahan N, Ward S, Martinson L, Riley J, Fraioli F, Al Bakir M, Grönroos E, Zambrana F, Endozo R, Bi WL, Fennessy FM, Sponer N, Johnson D, Laycock J, Shafi S, Czyzewska-Khan J, Rowan A, Chambers T, Matthews N, Turajlic S, Hiley C, Lee SM, Forster MD, Ahmad T, Falzon M, Borg E, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Hafez D, Naik A, Ganguly A, Kareht S, Shah R, Joseph L, Marie Quinn A, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Oukrif D, Akarca AU, Hartley JA, Lowe HL, Lock S, Iles N, Bell H, Ngai Y, Elgar G, Szallasi Z, Schwarz RF, Herrero J, Stewart A, Quezada SA, Peggs KS, Van Loo P, Dive C, Lin CJ, Rabinowitz M, Aerts HJWL, Hackshaw A, Shaw JA, Zimmermann BG; TRACERx consortium; PEACE consortium, Swanton C.

Nature. 2017 Apr 26;545(7655):446-451. doi: 10.1038/nature22364. Erratum in: Nature. 2017 Dec 20;:.

19.

Tracking the Evolution of Non-Small-Cell Lung Cancer.

Jamal-Hanjani M, Wilson GA, McGranahan N, Birkbak NJ, Watkins TBK, Veeriah S, Shafi S, Johnson DH, Mitter R, Rosenthal R, Salm M, Horswell S, Escudero M, Matthews N, Rowan A, Chambers T, Moore DA, Turajlic S, Xu H, Lee SM, Forster MD, Ahmad T, Hiley CT, Abbosh C, Falzon M, Borg E, Marafioti T, Lawrence D, Hayward M, Kolvekar S, Panagiotopoulos N, Janes SM, Thakrar R, Ahmed A, Blackhall F, Summers Y, Shah R, Joseph L, Quinn AM, Crosbie PA, Naidu B, Middleton G, Langman G, Trotter S, Nicolson M, Remmen H, Kerr K, Chetty M, Gomersall L, Fennell DA, Nakas A, Rathinam S, Anand G, Khan S, Russell P, Ezhil V, Ismail B, Irvin-Sellers M, Prakash V, Lester JF, Kornaszewska M, Attanoos R, Adams H, Davies H, Dentro S, Taniere P, O'Sullivan B, Lowe HL, Hartley JA, Iles N, Bell H, Ngai Y, Shaw JA, Herrero J, Szallasi Z, Schwarz RF, Stewart A, Quezada SA, Le Quesne J, Van Loo P, Dive C, Hackshaw A, Swanton C; TRACERx Consortium.

N Engl J Med. 2017 Jun 1;376(22):2109-2121. doi: 10.1056/NEJMoa1616288. Epub 2017 Apr 26.

20.

Synthesis and in vitro evaluation of SG3227, a pyrrolobenzodiazepine dimer antibody-drug conjugate payload based on sibiromycin.

Kemp GC, Tiberghien AC, Patel NV, D'Hooge F, Nilapwar SM, Adams LR, Corbett S, Williams DG, Hartley JA, Howard PW.

Bioorg Med Chem Lett. 2017 Mar 1;27(5):1154-1158. doi: 10.1016/j.bmcl.2017.01.074. Epub 2017 Jan 30.

PMID:
28188066
21.

Design and Synthesis of Tesirine, a Clinical Antibody-Drug Conjugate Pyrrolobenzodiazepine Dimer Payload.

Tiberghien AC, Levy JN, Masterson LA, Patel NV, Adams LR, Corbett S, Williams DG, Hartley JA, Howard PW.

ACS Med Chem Lett. 2016 May 24;7(11):983-987. eCollection 2016 Nov 10.

22.

Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours.

Childs A, Vesely C, Ensell L, Lowe H, Luong TV, Caplin ME, Toumpanakis C, Thirlwell C, Hartley JA, Meyer T.

Br J Cancer. 2016 Dec 6;115(12):1540-1547. doi: 10.1038/bjc.2016.377. Epub 2016 Nov 22.

23.

ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.

Flynn MJ, Zammarchi F, Tyrer PC, Akarca AU, Janghra N, Britten CE, Havenith CE, Levy JN, Tiberghien A, Masterson LA, Barry C, D'Hooge F, Marafioti T, Parren PW, Williams DG, Howard PW, van Berkel PH, Hartley JA.

Mol Cancer Ther. 2016 Nov;15(11):2709-2721. Epub 2016 Aug 17.

24.

Development of Neural Sensitivity to Face Identity Correlates with Perceptual Discriminability.

Natu VS, Barnett MA, Hartley J, Gomez J, Stigliani A, Grill-Spector K.

J Neurosci. 2016 Oct 19;36(42):10893-10907.

25.

Modulation of topoisomerase IIα expression and chemosensitivity through targeted inhibition of NF-Y:DNA binding by a diamino p-anisyl-benzimidazole (Hx) polyamide.

Pett L, Kiakos K, Satam V, Patil P, Laughlin-Toth S, Gregory M, Bowerman M, Olson K, Savagian M, Lee M, Lee M, Wilson WD, Hochhauser D, Hartley JA.

Biochim Biophys Acta. 2017 May;1860(5):617-629. doi: 10.1016/j.bbagrm.2016.10.005. Epub 2016 Oct 24.

26.

Single Synonymous Mutations in KRAS Cause Transformed Phenotypes in NIH3T3 Cells.

Waters AM, Bagni R, Portugal F, Hartley JL.

PLoS One. 2016 Sep 29;11(9):e0163272. doi: 10.1371/journal.pone.0163272. eCollection 2016.

27.

A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours.

Mandair D, Vesely C, Ensell L, Lowe H, Spanswick V, Hartley JA, Caplin ME, Meyer T.

Endocr Relat Cancer. 2016 Oct;23(10):L29-32. doi: 10.1530/ERC-16-0201. Epub 2016 Aug 12. No abstract available.

28.
29.

What's new in abstracts of science articles.

Hartley J.

J Med Libr Assoc. 2016 Jul;104(3):235-6. doi: 10.3163/1536-5050.104.3.011. No abstract available.

30.

Surgical management of complicated and medically refractory inflammatory bowel disease during pregnancy.

Killeen S, Gunn J, Hartley J.

Colorectal Dis. 2017 Feb;19(2):123-138. doi: 10.1111/codi.13413. Review.

PMID:
27317641
31.

Recurrent life-threatening haemoptysis from a bleeding vertebral artery pseudoaneurysm: A diagnostic dilemma.

Chandran A, Biswas S, Hartley JL, Nahser HC, Lancaster J, Puthuran M.

Interv Neuroradiol. 2016 Oct;22(5):512-5. doi: 10.1177/1591019916653248. Epub 2016 Jun 17.

32.

Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer.

Lemech CR, Ensell L, Paterson JC, Eminowicz G, Lowe H, Arora R, Arkenau HT, Widschwendter M, MacDonald N, Olaitan A, Mould T, Meyer T, Hartley J, Mitra A, Ledermann JA, McCormack M, Kristeleit RS.

Oncology. 2016;91(1):48-54. doi: 10.1159/000445999. Epub 2016 Jun 3.

PMID:
27256106
33.

The MEK1/2 Inhibitor Pimasertib Enhances Gemcitabine Efficacy-Response.

Vena F, Hartley JA, Hochhauser D.

Clin Cancer Res. 2016 May 15;22(10):2595. doi: 10.1158/1078-0432.CCR-16-0566. No abstract available. Erratum in: Clin Cancer Res. 2016 Nov 15;22(22):5619.

34.

Successful therapy for protein-losing enteropathy caused by chronic neuronopathic Gaucher disease.

Mhanni AA, Kozenko M, Hartley JN, Deneau M, El-Matary W, Rockman-Greenberg C.

Mol Genet Metab Rep. 2015 Dec 29;6:13-5. doi: 10.1016/j.ymgmr.2015.12.001. eCollection 2016 Mar.

35.

Factors Affecting the Development of an Antibody Response to Hepatitis B Immunization in Children With Intestinal Failure: Before and After Small Bowel Transplantation (With and Without Liver Graft).

Craggs HM, Jackson P, Gupte G, Hartley J, Abdel-Hady M, Morton R, Beath S, Hogg L.

JPEN J Parenter Enteral Nutr. 2017 Aug;41(6):1030-1036. doi: 10.1177/0148607116637933. Epub 2016 Mar 9.

PMID:
26962060
36.
37.

Sequence Diversity, Intersubgroup Relationships, and Origins of the Mouse Leukemia Gammaretroviruses of Laboratory and Wild Mice.

Bamunusinghe D, Naghashfar Z, Buckler-White A, Plishka R, Baliji S, Liu Q, Kassner J, Oler AJ, Hartley J, Kozak CA.

J Virol. 2016 Mar 28;90(8):4186-98. doi: 10.1128/JVI.03186-15. Print 2016 Apr.

38.

Tracking and quantifying polymer therapeutic distribution on a cellular level using 3D dSTORM.

Hartley JM, Zhang R, Gudheti M, Yang J, Kopeček J.

J Control Release. 2016 Jun 10;231:50-9. doi: 10.1016/j.jconrel.2016.02.005. Epub 2016 Feb 16.

39.

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer.

Santoro V, Jia R, Thompson H, Nijhuis A, Jeffery R, Kiakos K, Silver AR, Hartley JA, Hochhauser D.

J Natl Cancer Inst. 2015 Dec 30;108(6):djv394. doi: 10.1093/jnci/djv394. Print 2016 Jun.

40.

Reply.

Moffett A, Hartley JDR, Ferguson BJ.

Am J Obstet Gynecol. 2016 Apr;214(4):548-549. doi: 10.1016/j.ajog.2015.12.004. Epub 2015 Dec 12. No abstract available.

PMID:
26692179
41.

NF-Y activates genes of metabolic pathways altered in cancer cells.

Benatti P, Chiaramonte ML, Lorenzo M, Hartley JA, Hochhauser D, Gnesutta N, Mantovani R, Imbriano C, Dolfini D.

Oncotarget. 2016 Jan 12;7(2):1633-50. doi: 10.18632/oncotarget.6453.

42.

Increased sensitivity to platinum drugs of cancer cells with acquired resistance to trabectedin.

Colmegna B, Uboldi S, Frapolli R, Licandro SA, Panini N, Galmarini CM, Badri N, Spanswick VJ, Bingham JP, Kiakos K, Erba E, Hartley JA, D'Incalci M.

Br J Cancer. 2015 Dec 22;113(12):1687-93. doi: 10.1038/bjc.2015.407. Epub 2015 Dec 3.

43.

The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.

Cantey PT, Weeks J, Edwards M, Rao S, Ostovar GA, Dehority W, Alzona M, Swoboda S, Christiaens B, Ballan W, Hartley J, Terranella A, Weatherhead J, Dunn JJ, Marx DP, Hicks MJ, Rauch RA, Smith C, Dishop MK, Handler MH, Dudley RW, Chundu K, Hobohm D, Feiz-Erfan I, Hakes J, Berry RS, Stepensaski S, Greenfield B, Shroeder L, Bishop H, de Almeida M, Mathison B, Eberhard M.

Clin Infect Dis. 2016 Mar 15;62(6):778-83. doi: 10.1093/cid/civ983. Epub 2015 Nov 26.

44.

Classic articles in Psychology in the Science Citation Index Expanded: A bibliometric analysis.

Ho YS, Hartley J.

Br J Psychol. 2016 Nov;107(4):768-780. doi: 10.1111/bjop.12163. Epub 2015 Nov 26.

PMID:
26607573
45.

Black silicon as a platform for bacterial detection.

Hartley JS, Hlaing MM, Seniutinas G, Juodkazis S, Stoddart PR.

Biomicrofluidics. 2015 Nov 3;9(6):061101. doi: 10.1063/1.4934966. eCollection 2015 Nov.

46.

Electrochemistry and speciation of Au(+) in a deep eutectic solvent: growth and morphology of galvanic immersion coatings.

Ballantyne AD, Forrest GC, Frisch G, Hartley JM, Ryder KS.

Phys Chem Chem Phys. 2015 Nov 11;17(45):30540-50. doi: 10.1039/c5cp05748e.

PMID:
26523806
47.
48.

Ataxia with oculomotor apraxia type 2 in the Canadian aboriginal population.

Mhanni AA, Hartley JN, Harward E, Spriggs E, Booth F.

Clin Genet. 2015 Aug 31. doi: 10.1111/cge.12650. [Epub ahead of print] No abstract available.

PMID:
26332941
49.

Genetically Encoded Azide Containing Amino Acid in Mammalian Cells Enables Site-Specific Antibody-Drug Conjugates Using Click Cycloaddition Chemistry.

VanBrunt MP, Shanebeck K, Caldwell Z, Johnson J, Thompson P, Martin T, Dong H, Li G, Xu H, D'Hooge F, Masterson L, Bariola P, Tiberghien A, Ezeadi E, Williams DG, Hartley JA, Howard PW, Grabstein KH, Bowen MA, Marelli M.

Bioconjug Chem. 2015 Nov 18;26(11):2249-60. doi: 10.1021/acs.bioconjchem.5b00359. Epub 2015 Sep 11.

PMID:
26332743
50.

Towards outperforming conventional sensor arrays with fabricated individual photonic vapour sensors inspired by Morpho butterflies.

Potyrailo RA, Bonam RK, Hartley JG, Starkey TA, Vukusic P, Vasudev M, Bunning T, Naik RR, Tang Z, Palacios MA, Larsen M, Le Tarte LA, Grande JC, Zhong S, Deng T.

Nat Commun. 2015 Sep 1;6:7959. doi: 10.1038/ncomms8959.

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