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Pathogenesis, imaging and clinical characteristics of CF and non-CF bronchiectasis.

Schäfer J, Griese M, Chandrasekaran R, Chotirmall SH, Hartl D.

BMC Pulm Med. 2018 May 22;18(1):79. doi: 10.1186/s12890-018-0630-8. Review.


Correction: mRNA-Mediated Gene Supplementation of Toll-Like Receptors as Treatment Strategy for Asthma In Vivo.

Zeyer F, Mothes B, Will C, Carevic M, Rottenberger J, Nürnberg B, Hartl D, Handgretinger R, Beer-Hammer S, Kormann MSD.

PLoS One. 2018 May 15;13(5):e0197705. doi: 10.1371/journal.pone.0197705. eCollection 2018.


De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria.

Redmond SN, MacInnis BM, Bopp S, Bei AK, Ndiaye D, Hartl DL, Wirth DF, Volkman SK, Neafsey DE.

Mol Biol Evol. 2018 May 1. doi: 10.1093/molbev/msy059. [Epub ahead of print]


Challenging pre-surgical localization of hyperfunctioning parathyroid glands in primary hyperparathyroidism: the added value of 18F-Fluorocholine PET/CT.

Grimaldi S, Young J, Kamenicky P, Hartl D, Terroir M, Leboulleux S, Berdelou A, Hadoux J, Hescot S, Remy H, Baudin E, Schlumberger M, Deandreis D.

Eur J Nucl Med Mol Imaging. 2018 Apr 22. doi: 10.1007/s00259-018-4018-z. [Epub ahead of print]


Rare ABCA7 variants in 2 German families with Alzheimer disease.

May P, Pichler S, Hartl D, Bobbili DR, Mayhaus M, Spaniol C, Kurz A, Balling R, Schneider JG, Riemenschneider M.

Neurol Genet. 2018 Mar 21;4(2):e224. doi: 10.1212/NXG.0000000000000224. eCollection 2018 Apr.


Mechanisms and disease relevance of neutrophil extracellular trap formation.

Van Avondt K, Hartl D.

Eur J Clin Invest. 2018 Mar 15:e12919. doi: 10.1111/eci.12919. [Epub ahead of print] Review.


Surgical management of the recurrent laryngeal nerve in thyroidectomy: American Head and Neck Society Consensus Statement.

Fundakowski CE, Hales NW, Agrawal N, Barczyński M, Camacho PM, Hartl DM, Kandil E, Liddy WE, McKenzie TJ, Morris JC, Ridge JA, Schneider R, Serpell J, Sinclair CF, Snyder SK, Terris DJ, Tuttle RM, Wu CW, Wong RJ, Zafereo M, Randolph GW.

Head Neck. 2018 Apr;40(4):663-675. doi: 10.1002/hed.24928. Epub 2018 Feb 20.


Innate Immunity of the Lung: From Basic Mechanisms to Translational Medicine.

Hartl D, Tirouvanziam R, Laval J, Greene CM, Habiel D, Sharma L, Yildirim AÖ, Dela Cruz CS, Hogaboam CM.

J Innate Immun. 2018 Feb 13. doi: 10.1159/000487057. [Epub ahead of print]


Macrophages and platelets join forces to release kidney-damaging DNA traps.

Hartl D.

Nat Med. 2018 Feb 7;24(2):128-129. doi: 10.1038/nm.4486. No abstract available.


Dramatic Changes in Malaria Population Genetic Complexity in Dielmo and Ndiop, Senegal, Revealed Using Genomic Surveillance.

Bei AK, Niang M, Deme AB, Daniels RF, Sarr FD, Sokhna C, Talla C, Faye J, Diagne N, Doucoure S, Mboup S, Wirth DF, Tall A, Ndiaye D, Hartl DL, Volkman SK, Toure-Balde A.

J Infect Dis. 2018 Jan 30;217(4):622-627. doi: 10.1093/infdis/jix580.


Modeling the genetic relatedness of Plasmodium falciparum parasites following meiotic recombination and cotransmission.

Wong W, Wenger EA, Hartl DL, Wirth DF.

PLoS Comput Biol. 2018 Jan 9;14(1):e1005923. doi: 10.1371/journal.pcbi.1005923. eCollection 2018 Jan.


An informative intragenic microsatellite marker suggests the IL-1 receptor as a genetic modifier in cystic fibrosis.

Stanke F, Hector A, Hedtfeld S, Hartl D, Griese M, Tümmler B, Mall MA.

Eur Respir J. 2017 Dec 28;50(6). pii: 1700426. doi: 10.1183/13993003.00426-2017. Print 2017 Dec. No abstract available.


Rescue transtracheal jet ventilation during difficult intubation in patients with upper airway cancer.

Bouroche G, Motamed C, de Guibert JM, Hartl D, Bourgain JL.

Anaesth Crit Care Pain Med. 2017 Nov 10. pii: S2352-5568(17)30102-9. doi: 10.1016/j.accpm.2017.10.005. [Epub ahead of print]


Janus-Faced Neutrophil Extracellular Traps in Periodontitis.

Vitkov L, Hartl D, Minnich B, Hannig M.

Front Immunol. 2017 Oct 26;8:1404. doi: 10.3389/fimmu.2017.01404. eCollection 2017. Review.


Diagnostic and prognostic value of 18F-FDG PET, CT, and MRI in perineural spread of head and neck malignancies.

Dercle L, Hartl D, Rozenblum-Beddok L, Mokrane FZ, Seban RD, Yeh R, Bidault F, Ammari S.

Eur Radiol. 2018 Apr;28(4):1761-1770. doi: 10.1007/s00330-017-5063-x. Epub 2017 Oct 30.


Cis-regulatory landscapes of four cell types of the retina.

Hartl D, Krebs AR, Jüttner J, Roska B, Schübeler D.

Nucleic Acids Res. 2017 Nov 16;45(20):11607-11621. doi: 10.1093/nar/gkx923.


Cohort Profile: The Madagascar Health and Environmental Research (MAHERY) study in north-eastern Madagascar.

Golden CD, Anjaranirina EJG, Fernald LCH, Hartl DL, Kremen C, Milner DA Jr, Ralalason DH, Ramihantaniarivo H, Randriamady H, Rice BL, Vaitla B, Volkman SK, Vonona MA, Myers SS.

Int J Epidemiol. 2017 Dec 1;46(6):1747-1748d. doi: 10.1093/ije/dyx071. No abstract available.


Expression of checkpoint molecules on myeloid-derived suppressor cells.

Ballbach M, Dannert A, Singh A, Siegmund DM, Handgretinger R, Piali L, Rieber N, Hartl D.

Immunol Lett. 2017 Dec;192:1-6. doi: 10.1016/j.imlet.2017.10.001. Epub 2017 Oct 4.


Autophagy Traps Neutrophils into a Protective Alliance during Sepsis.

Laval J, Singh A, Hartl D.

Am J Respir Crit Care Med. 2017 Sep 1;196(5):537-538. doi: 10.1164/rccm.201701-0149ED. No abstract available.


Transcriptomic profile of cystic fibrosis patients identifies type I interferon response and ribosomal stalk proteins as potential modifiers of disease severity.

Kormann MSD, Dewerth A, Eichner F, Baskaran P, Hector A, Regamey N, Hartl D, Handgretinger R, Antony JS.

PLoS One. 2017 Aug 28;12(8):e0183526. doi: 10.1371/journal.pone.0183526. eCollection 2017.


Response assessment after induction chemotherapy for head and neck squamous cell carcinoma: From physical examination to modern imaging techniques and beyond.

de Bree R, Wolf GT, de Keizer B, Nixon IJ, Hartl DM, Forastiere AA, Haigentz M Jr, Rinaldo A, Rodrigo JP, Saba NF, Suárez C, Vermorken JB, Ferlito A.

Head Neck. 2017 Nov;39(11):2329-2349. doi: 10.1002/hed.24883. Epub 2017 Aug 17. Review.


Fungal Pathogens in CF Airways: Leave or Treat?

Singh A, Ralhan A, Schwarz C, Hartl D, Hector A.

Mycopathologia. 2018 Feb;183(1):119-137. doi: 10.1007/s11046-017-0184-y. Epub 2017 Aug 2.


Progress in Definition, Prevention and Treatment of Fungal Infections in Cystic Fibrosis.

Schwarz C, Hartl D, Eickmeier O, Hector A, Benden C, Durieu I, Sole A, Gartner S, Milla CE, Barry PJ.

Mycopathologia. 2018 Feb;183(1):21-32. doi: 10.1007/s11046-017-0182-0. Epub 2017 Jul 31. Review.


Dimethyl fumarate modulates neutrophil extracellular trap formation in a glutathione- and superoxide-dependent manner.

Hoffmann JHO, Schaekel K, Hartl D, Enk AH, Hadaschik EN.

Br J Dermatol. 2018 Jan;178(1):207-214. doi: 10.1111/bjd.15839. Epub 2017 Dec 14.


Myeloid-derived suppressor cells modulate B-cell responses.

Lelis FJN, Jaufmann J, Singh A, Fromm K, Teschner AC, Pöschel S, Schäfer I, Beer-Hammer S, Rieber N, Hartl D.

Immunol Lett. 2017 Aug;188:108-115. doi: 10.1016/j.imlet.2017.07.003. Epub 2017 Jul 4.


A semiquantitative MRI-Score can predict loss of lung function in patients with cystic fibrosis: Preliminary results.

Schaefer JF, Hector A, Schmidt K, Teufel M, Fleischer S, Graepler-Mainka U, Riethmueller J, Gatidis S, Schaefer S, Nikolaou K, Hartl D, Tsiflikas I.

Eur Radiol. 2018 Jan;28(1):74-84. doi: 10.1007/s00330-017-4870-4. Epub 2017 Jun 29.


Toxicities of systemic agents in squamous cell carcinoma of the head and neck (SCCHN); A new perspective in the era of immunotherapy.

Saba NF, Mody MD, Tan ES, Gill HS, Rinaldo A, Takes RP, Strojan P, Hartl DM, Vermorken JB, Haigentz M Jr, Ferlito A.

Crit Rev Oncol Hematol. 2017 Jul;115:50-58. doi: 10.1016/j.critrevonc.2017.04.011. Epub 2017 Apr 27. Review.


Design and simulation of origami structures with smooth folds.

Peraza Hernandez EA, Hartl DJ, Lagoudas DC.

Proc Math Phys Eng Sci. 2017 Apr;473(2200):20160716. doi: 10.1098/rspa.2016.0716. Epub 2017 Apr 26.


Surgery for Neck Recurrence of Differentiated Thyroid Cancer: Outcomes and Risk Factors.

Lamartina L, Borget I, Mirghani H, Al Ghuzlan A, Berdelou A, Bidault F, Deandreis D, Baudin E, Travagli JP, Schlumberger M, Hartl DM, Leboulleux S.

J Clin Endocrinol Metab. 2017 Mar 1;102(3):1020-1031. doi: 10.1210/jc.2016-3284.


Ethical issues in non-intervention trials for thyroid cancer.

Angelos P, Hartl DM, Shah JP, Nixon IJ, Owen RP, Rinaldo A, Rodrigo JP, Shaha AR, Silver CE, Suárez C, Ferlito A.

Eur J Surg Oncol. 2018 Mar;44(3):316-320. doi: 10.1016/j.ejso.2017.03.002. Epub 2017 Mar 16.


Pulmonary manifestations of rheumatologic diseases.

Cidon M, Bansal M, Hartl D.

Curr Opin Pediatr. 2017 Jun;29(3):311-319. doi: 10.1097/MOP.0000000000000496. Review.


Otorhinolaryngological Toxicities of New Drugs in Oncology.

Hartl DM, Morel D, Saavedra E, Massard C, Rinaldo A, Saba NF, Ferlito A, Soria JC.

Adv Ther. 2017 Apr;34(4):866-894. doi: 10.1007/s12325-017-0512-0. Epub 2017 Mar 17. Review.


Lost in neutrophil heterogeneity? CD10!

Brandau S, Hartl D.

Blood. 2017 Mar 9;129(10):1240-1241. doi: 10.1182/blood-2017-01-761585. No abstract available.


Suspicion of respiratory tract infection with multidrug-resistant Enterobacteriaceae: epidemiology and risk factors from a Paediatric Intensive Care Unit.

Renk H, Stoll L, Neunhoeffer F, Hölzl F, Kumpf M, Hofbeck M, Hartl D.

BMC Infect Dis. 2017 Feb 21;17(1):163. doi: 10.1186/s12879-017-2251-x.


Human NACHT, LRR, and PYD domain-containing protein 3 (NLRP3) inflammasome activity is regulated by and potentially targetable through Bruton tyrosine kinase.

Liu X, Pichulik T, Wolz OO, Dang TM, Stutz A, Dillen C, Delmiro Garcia M, Kraus H, Dickhöfer S, Daiber E, Münzenmayer L, Wahl S, Rieber N, Kümmerle-Deschner J, Yazdi A, Franz-Wachtel M, Macek B, Radsak M, Vogel S, Schulte B, Walz JS, Hartl D, Latz E, Stilgenbauer S, Grimbacher B, Miller L, Brunner C, Wolz C, Weber ANR.

J Allergy Clin Immunol. 2017 Oct;140(4):1054-1067.e10. doi: 10.1016/j.jaci.2017.01.017. Epub 2017 Feb 16.


In Vivo Hypoxia PET Imaging Quantifies the Severity of Arthritic Joint Inflammation in Line with Overexpression of Hypoxia-Inducible Factor and Enhanced Reactive Oxygen Species Generation.

Fuchs K, Kuehn A, Mahling M, Guenthoer P, Hector A, Schwenck J, Hartl D, Laufer S, Kohlhofer U, Quintanilla-Martinez L, Reischl G, Röcken M, Pichler BJ, Kneilling M.

J Nucl Med. 2017 May;58(5):853-860. doi: 10.2967/jnumed.116.185934. Epub 2017 Feb 9.


Genome-Wide Association Studies of Drug-Resistance Determinants.

Volkman SK, Herman J, Lukens AK, Hartl DL.

Trends Parasitol. 2017 Mar;33(3):214-230. doi: 10.1016/ Epub 2016 Oct 27. Review.


Prospective multicenter German study on pulmonary colonization with Scedosporium /Lomentospora species in cystic fibrosis: Epidemiology and new association factors.

Schwarz C, Brandt C, Antweiler E, Krannich A, Staab D, Schmitt-Grohé S, Fischer R, Hartl D, Thronicke A, Tintelnot K.

PLoS One. 2017 Feb 8;12(2):e0171485. doi: 10.1371/journal.pone.0171485. eCollection 2017.


Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal.

Wong W, Griggs AD, Daniels RF, Schaffner SF, Ndiaye D, Bei AK, Deme AB, MacInnis B, Volkman SK, Hartl DL, Neafsey DE, Wirth DF.

Genome Med. 2017 Jan 24;9(1):5. doi: 10.1186/s13073-017-0398-0.


Early assessment of feasibility and technical specificities of transoral robotic surgery using the da Vinci Xi.

Gorphe P, Von Tan J, El Bedoui S, Hartl DM, Auperin A, Qassemyar Q, Moya-Plana A, Janot F, Julieron M, Temam S.

J Robot Surg. 2017 Dec;11(4):455-461. doi: 10.1007/s11701-017-0679-z. Epub 2017 Jan 7.


Cellular Innate Immunity: An Old Game with New Players.

Gasteiger G, D'Osualdo A, Schubert DA, Weber A, Bruscia EM, Hartl D.

J Innate Immun. 2017;9(2):111-125. doi: 10.1159/000453397. Epub 2016 Dec 23. Review.


Genetic evidence that the Makira region in northeastern Madagascar is a hotspot of malaria transmission.

Rice BL, Golden CD, Anjaranirina EJ, Botelho CM, Volkman SK, Hartl DL.

Malar J. 2016 Dec 20;15(1):596. doi: 10.1186/s12936-016-1644-4.


Pseudomonas aeruginosa Airway Infection Recruits and Modulates Neutrophilic Myeloid-Derived Suppressor Cells.

Öz HH, Zhou B, Voss P, Carevic M, Schroth C, Frey N, Rieber N, Hector A, Hartl D.

Front Cell Infect Microbiol. 2016 Nov 29;6:167. eCollection 2016.


The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster.

Pichler S, Gu W, Hartl D, Gasparoni G, Leidinger P, Keller A, Meese E, Mayhaus M, Hampel H, Riemenschneider M.

Neurobiol Aging. 2017 Feb;50:167.e1-167.e10. doi: 10.1016/j.neurobiolaging.2016.09.019. Epub 2016 Oct 3.


Innate Immunity in Cystic Fibrosis: Novel Pieces of the Puzzle.

Öz HH, Hartl D.

J Innate Immun. 2016;8(6):529-530. Epub 2016 Aug 19. No abstract available.


Current Concepts and Controversies in Innate Immunity of Cystic Fibrosis Lung Disease.

Ralhan A, Laval J, Lelis F, Ballbach M, Grund C, Hector A, Hartl D.

J Innate Immun. 2016;8(6):531-540. Epub 2016 Jul 1. Review.


The intensity of 18FDG uptake does not predict tumor growth in patients with metastatic differentiated thyroid cancer.

Terroir M, Borget I, Bidault F, Ricard M, Deschamps F, Hartl D, Tselikas L, Dercle L, Lumbroso J, Baudin E, Berdelou A, Deandreis D, Schlumberger M, Leboulleux S.

Eur J Nucl Med Mol Imaging. 2017 Apr;44(4):638-646. doi: 10.1007/s00259-016-3551-x. Epub 2016 Oct 29.


Differential Regulation of Myeloid-Derived Suppressor Cells by Candida Species.

Singh A, Lelis F, Braig S, Schäfer I, Hartl D, Rieber N.

Front Microbiol. 2016 Oct 13;7:1624. eCollection 2016.


Extrapulmonary Aspergillus infection in patients with CARD9 deficiency.

Rieber N, Gazendam RP, Freeman AF, Hsu AP, Collar AL, Sugui JA, Drummond RA, Rongkavilit C, Hoffman K, Henderson C, Clark L, Mezger M, Swamydas M, Engeholm M, Schüle R, Neumayer B, Ebel F, Mikelis CM, Pittaluga S, Prasad VK, Singh A, Milner JD, Williams KW, Lim JK, Kwon-Chung KJ, Holland SM, Hartl D, Kuijpers TW, Lionakis MS.

JCI Insight. 2016 Oct 20;1(17):e89890.


A New Take on John Maynard Smith's Concept of Protein Space for Understanding Molecular Evolution.

Ogbunugafor CB, Hartl DL.

PLoS Comput Biol. 2016 Oct 13;12(10):e1005046. doi: 10.1371/journal.pcbi.1005046. eCollection 2016 Oct.

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