Format

Send to

Choose Destination
Gut. 2018 Jan;67(1):6-19. doi: 10.1136/gutjnl-2017-314924. Epub 2017 Nov 9.

Guidelines on the management of abnormal liver blood tests.

Author information

1
National Institute for Health Research (NIHR), Birmingham Biomedical Research Centre and Centre for Liver Research, University of Birmingham, Birmingham, UK.
2
Centre for Liver Research, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
3
Leeds Children's Hospital, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
4
Division of Molecular and Clinical Medicine, School of Medicine, University of Dundee, Dundee, UK.
5
The Pool Medical Centre, Studley, UK.
6
Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
7
Liver4Life, Dorset, UK.
8
Public Health England, South West, UK.
9
Regional Liver and Transplant Unit, Freeman Hospital, Newcastle Upon Tyne, UK.
10
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
11
British Liver Trust, Bournemouth, UK.
12
PBC Foundation, Edinburgh, UK.
13
Killick Street Health Centre, London, UK.
14
NHS Islington Clinical Commissioning Group, London, UK.
15
Clinical and Experimental Science, Faculty of Medicine, University of Southampton, Southampton, UK.
16
Chair of Trustees PSC Support, Didcot, UK.
17
Gwent Liver Unit, Royal Gwent Hospital, Newport, UK.

Abstract

These updated guidelines on the management of abnormal liver blood tests have been commissioned by the Clinical Services and Standards Committee (CSSC) of the British Society of Gastroenterology (BSG) under the auspices of the liver section of the BSG. The original guidelines, which this document supersedes, were written in 2000 and have undergone extensive revision by members of the Guidelines Development Group (GDG). The GDG comprises representatives from patient/carer groups (British Liver Trust, Liver4life, PBC Foundation and PSC Support), elected members of the BSG liver section (including representatives from Scotland and Wales), British Association for the Study of the Liver (BASL), Specialist Advisory Committee in Clinical Biochemistry/Royal College of Pathology and Association for Clinical Biochemistry, British Society of Paediatric Gastroenterology, Hepatology and Nutrition (BSPGHAN), Public Health England (implementation and screening), Royal College of General Practice, British Society of Gastrointestinal and Abdominal Radiologists (BSGAR) and Society of Acute Medicine. The quality of evidence and grading of recommendations was appraised using the AGREE II tool. These guidelines deal specifically with the management of abnormal liver blood tests in children and adults in both primary and secondary care under the following subheadings: (1) What constitutes an abnormal liver blood test? (2) What constitutes a standard liver blood test panel? (3) When should liver blood tests be checked? (4) Does the extent and duration of abnormal liver blood tests determine subsequent investigation? (5) Response to abnormal liver blood tests. They are not designed to deal with the management of the underlying liver disease.

KEYWORDS:

alcoholic liver disease; fibrosis; liver; nonalcoholic steatohepatitis

PMID:
29122851
PMCID:
PMC5754852
DOI:
10.1136/gutjnl-2017-314924
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center