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Items: 29

1.

The nuclear translocation of the kinases p38 and JNK promotes inflammation-induced cancer.

Maik-Rachline G, Zehorai E, Hanoch T, Blenis J, Seger R.

Sci Signal. 2018 Apr 10;11(525). pii: eaao3428. doi: 10.1126/scisignal.aao3428.

PMID:
29636389
2.

Activation of Signaling Cascades by Weak Extremely Low Frequency Electromagnetic Fields.

Kapri-Pardes E, Hanoch T, Maik-Rachline G, Murbach M, Bounds PL, Kuster N, Seger R.

Cell Physiol Biochem. 2017;43(4):1533-1546. doi: 10.1159/000481977. Epub 2017 Oct 16.

3.

Correction for Aebersold et al., "Extracellular Signal-Regulated Kinase 1c (ERK1c), a Novel 42-Kilodalton ERK, Demonstrates Unique Modes of Regulation, Localization, and Function".

Aebersold DM, Shaul YD, Yung Y, Yarom N, Yao Z, Hanoch T, Seger R.

Mol Cell Biol. 2017 Aug 28;37(18). pii: e00322-17. doi: 10.1128/MCB.00322-17. Print 2017 Sep 15. No abstract available.

4.

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK.

Yung Y, Yao Z, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8854. doi: 10.1074/jbc.A117.910060. No abstract available.

5.

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring.

Wolf I, Rubinfeld H, Yoon S, Marmor G, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8853. doi: 10.1074/jbc.A117.103352. No abstract available.

6.

Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs.

Yung Y, Yao Z, Aebersold DM, Hanoch T, Seger R.

J Biol Chem. 2017 May 26;292(21):8852. doi: 10.1074/jbc.A117.105995. No abstract available.

7.

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.

Seger R, Hanoch T, Rosenberg R, Dantes A, Merz WE, Strauss JF 3rd, Amsterdam A.

J Biol Chem. 2017 May 26;292(21):8847. doi: 10.1074/jbc.A117.006852. No abstract available.

8.

Myotubularin-related protein 7 inhibits insulin signaling in colorectal cancer.

Weidner P, Söhn M, Gutting T, Friedrich T, Gaiser T, Magdeburg J, Kienle P, Ruh H, Hopf C, Behrens HM, Röcken C, Hanoch T, Seger R, Ebert MP, Burgermeister E.

Oncotarget. 2016 Aug 2;7(31):50490-50506. doi: 10.18632/oncotarget.10466.

9.

Mitotic Golgi translocation of ERK1c is mediated by a PI4KIIIβ-14-3-3γ shuttling complex.

Wortzel I, Hanoch T, Porat Z, Hausser A, Seger R.

J Cell Sci. 2015 Nov 15;128(22):4083-95. doi: 10.1242/jcs.170910. Epub 2015 Oct 12.

10.

Regulation of cell proliferation by ERK and signal-dependent nuclear translocation of ERK is dependent on Tm5NM1-containing actin filaments.

Schevzov G, Kee AJ, Wang B, Sequeira VB, Hook J, Coombes JD, Lucas CA, Stehn JR, Musgrove EA, Cretu A, Assoian R, Fath T, Hanoch T, Seger R, Pleines I, Kile BT, Hardeman EC, Gunning PW.

Mol Biol Cell. 2015 Jul 1;26(13):2475-90. doi: 10.1091/mbc.E14-10-1453. Epub 2015 May 13.

11.

The nuclear translocation of ERK1/2 as an anticancer target.

Plotnikov A, Flores K, Maik-Rachline G, Zehorai E, Kapri-Pardes E, Berti DA, Hanoch T, Besser MJ, Seger R.

Nat Commun. 2015 Mar 30;6:6685. doi: 10.1038/ncomms7685.

PMID:
25819065
12.

Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation.

Lev-Goldman V, Mester B, Ben-Aroya N, Hanoch T, Rupp B, Stanoeva T, Gescheidt G, Seger R, Koch Y, Weiner L, Fridkin M.

Bioorg Med Chem. 2008 Jul 15;16(14):6789-98. doi: 10.1016/j.bmc.2008.05.057. Epub 2008 Jun 19.

PMID:
18571926
13.

Interaction with MEK causes nuclear export and downregulation of peroxisome proliferator-activated receptor gamma.

Burgermeister E, Chuderland D, Hanoch T, Meyer M, Liscovitch M, Seger R.

Mol Cell Biol. 2007 Feb;27(3):803-17. Epub 2006 Nov 13.

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Mechanisms of gonadotropin desensitization.

Amsterdam A, Hanoch T, Dantes A, Tajima K, Strauss JF, Seger R.

Mol Cell Endocrinol. 2002 Feb 22;187(1-2):69-74. Review.

PMID:
11988313
19.
20.

Involvement of the activation loop of ERK in the detachment from cytosolic anchoring.

Wolf I, Rubinfeld H, Yoon S, Marmor G, Hanoch T, Seger R.

J Biol Chem. 2001 Jul 6;276(27):24490-7. Epub 2001 Apr 27. Retraction in: J Biol Chem. 2017 May 26;292(21):8853.

21.

The ERK signaling cascade inhibits gonadotropin-stimulated steroidogenesis.

Seger R, Hanoch T, Rosenberg R, Dantes A, Merz WE, Strauss JF 3rd, Amsterdam A.

J Biol Chem. 2001 Apr 27;276(17):13957-64. Epub 2001 Jan 22. Retraction in: J Biol Chem. 2017 May 26;292(21):8847.

22.

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK.

Yung Y, Yao Z, Hanoch T, Seger R.

J Biol Chem. 2000 May 26;275(21):15799-808. Retraction in: J Biol Chem. 2017 May 26;292(21):8854.

23.

Detection of partially phosphorylated forms of ERK by monoclonal antibodies reveals spatial regulation of ERK activity by phosphatases.

Yao Z, Dolginov Y, Hanoch T, Yung Y, Ridner G, Lando Z, Zharhary D, Seger R.

FEBS Lett. 2000 Feb 18;468(1):37-42.

24.

Identification of a cytoplasmic-retention sequence in ERK2.

Rubinfeld H, Hanoch T, Seger R.

J Biol Chem. 1999 Oct 22;274(43):30349-52.

25.

Hippocampal plasticity involves extensive gene induction and multiple cellular mechanisms.

Hevroni D, Rattner A, Bundman M, Lederfein D, Gabarah A, Mangelus M, Silverman MA, Kedar H, Naor C, Kornuc M, Hanoch T, Seger R, Theill LE, Nedivi E, Richter-Levin G, Citri Y.

J Mol Neurosci. 1998 Apr;10(2):75-98. Review.

PMID:
9699150
26.

Stimulation of Jun N-terminal kinase (JNK) by gonadotropin-releasing hormone in pituitary alpha T3-1 cell line is mediated by protein kinase C, c-Src, and CDC42.

Levi NL, Hanoch T, Benard O, Rozenblat M, Harris D, Reiss N, Naor Z, Seger R.

Mol Endocrinol. 1998 Jun;12(6):815-24.

PMID:
9626657
27.

Detection of ERK activation by a novel monoclonal antibody.

Yung Y, Dolginov Y, Yao Z, Rubinfeld H, Michael D, Hanoch T, Roubini E, Lando Z, Zharhary D, Seger R.

FEBS Lett. 1997 May 26;408(3):292-6.

28.

Nuclear translocation of mitogen-activated protein kinase kinase (MEK1) in response to mitogenic stimulation.

Jaaro H, Rubinfeld H, Hanoch T, Seger R.

Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):3742-7.

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