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Items: 1 to 50 of 150

1.

Identification of two calcineurin B-binding proteins: tubulin and heat shock protein 60.

Li W, Handschumacher RE.

Biochim Biophys Acta. 2002 Sep 23;1599(1-2):72-81.

PMID:
12479407
2.

Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update.

Pizzorno G, Cao D, Leffert JJ, Russell RL, Zhang D, Handschumacher RE.

Biochim Biophys Acta. 2002 Jul 18;1587(2-3):133-44. Review.

3.

Uridine phosphorylase association with vimentin. Intracellular distribution and localization.

Russell RL, Cao D, Zhang D, Handschumacher RE, Pizzorno G.

J Biol Chem. 2001 Apr 20;276(16):13302-7. Epub 2001 Jan 24.

4.

Genomic structure, chromosomal mapping, and promoter region analysis of murine uridine phosphorylase gene.

Cao D, Nimmakayalu MA, Wang F, Zhang D, Handschumacher RE, Bray-Ward P, Pizzorno G.

Cancer Res. 1999 Oct 1;59(19):4997-5001.

5.

beta-alanine and alpha-fluoro-beta-alanine concentrative transport in rat hepatocytes is mediated by GABA transporter GAT-2.

Liu M, Russell RL, Beigelman L, Handschumacher RE, Pizzorno G.

Am J Physiol. 1999 Jan;276(1 Pt 1):G206-10.

PMID:
9886997
6.
7.

Discrete roles of hepatocytes and nonparenchymal cells in uridine catabolism as a component of its homeostasis.

Liu MP, Beigelman L, Levy E, Handschumacher RE, Pizzorno G.

Am J Physiol. 1998 Jun;274(6 Pt 1):G1018-23.

PMID:
9696700
8.

Phase I clinical and pharmacological studies of benzylacyclouridine, a uridine phosphorylase inhibitor.

Pizzorno G, Yee L, Burtness BA, Marsh JC, Darnowski JW, Chu MY, Chu SH, Chu E, Leffert JJ, Handschumacher RE, Calabresi P.

Clin Cancer Res. 1998 May;4(5):1165-75.

9.

HIV protease substrate conformation: modulation by cyclophilin A.

McCornack MA, Kakalis LT, Caserta C, Handschumacher RE, Armitage IM.

FEBS Lett. 1997 Sep 1;414(1):84-8.

10.

Pharmacokinetic and phase I trial of intraperitoneal carboplatin and cyclosporine in refractory ovarian cancer patients.

Chambers SK, Chambers JT, Davis CA, Kohorn EI, Schwartz PE, Lorber MI, Handschumacher RE, Pizzorno G.

J Clin Oncol. 1997 May;15(5):1945-52.

PMID:
9164206
11.

Regulation of the nuclear factor of activated T cells in stably transfected Jurkat cell clones.

Li W, Handschumacher RE.

Biochem Biophys Res Commun. 1996 Feb 6;219(1):96-9.

PMID:
8619834
12.

Tamoxifen induces Na+ -dependent uridine transport and dome formation in a human breast tumor cell line.

Liu MP, Handschumacher RE.

Cancer J Sci Am. 1995 Sep-Oct;1(3):210-4.

PMID:
9166478
13.
15.

Expression of human cyclophilin-40 and the effect of the His141-->Trp mutation on catalysis and cyclosporin A binding.

Hoffmann K, Kakalis LT, Anderson KS, Armitage IM, Handschumacher RE.

Eur J Biochem. 1995 Apr 1;229(1):188-93.

16.

Cyclophilin-40: evidence for a dimeric complex with hsp90.

Hoffmann K, Handschumacher RE.

Biochem J. 1995 Apr 1;307 ( Pt 1):5-8.

17.

Toxoplasma gondii tachyzoites possess an unusual plasma membrane adenosine transporter.

Schwab JC, Afifi Afifi M, Pizzorno G, Handschumacher RE, Joiner KA.

Mol Biochem Parasitol. 1995 Mar;70(1-2):59-69.

PMID:
7637715
18.
19.

Aberrant cell cycle inhibition pattern in human colon carcinoma cell lines after exposure to 5-fluorouracil.

Pizzorno G, Sun Z, Handschumacher RE.

Biochem Pharmacol. 1995 Feb 14;49(4):553-7.

PMID:
7872961
20.
21.

Differentiation of HL-60 cells by dimethylsulfoxide activates a Na(+)-dependent nucleoside transport system.

Lee CW, Sokoloski JA, Sartorelli AC, Handschumacher RE.

In Vivo. 1994 Nov-Dec;8(5):795-801.

PMID:
7727727
22.
23.
24.

Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterization.

Kieffer LJ, Seng TW, Li W, Osterman DG, Handschumacher RE, Bayney RM.

J Biol Chem. 1993 Jun 15;268(17):12303-10.

25.

Autoantibodies against cyclophilin in systemic lupus erythematosus and Lyme disease.

Kratz A, Harding MW, Craft J, Mackworth-Young CG, Handschumacher RE.

Clin Exp Immunol. 1992 Dec;90(3):422-7.

26.

Immunofluorescent localization and immunochemical determination of cyclophilin-A with specific rabbit antisera.

Sarris AH, Harding MW, Jiang TR, Aftab D, Handschumacher RE.

Transplantation. 1992 Nov;54(5):904-10.

PMID:
1440857
27.

Leukocyte chemotactic activity of cyclophilin.

Xu Q, Leiva MC, Fischkoff SA, Handschumacher RE, Lyttle CR.

J Biol Chem. 1992 Jun 15;267(17):11968-71.

28.

Immunity, microbial pathogenesis, and immunophilins: finding the keys, now where are the locks?

High KP, Handschumacher RE.

Infect Agents Dis. 1992 Jun;1(3):121-35. Review.

PMID:
1285413
29.

Isolation and partial characterization of membrane-associated cyclophilin and a related 22-kDa glycoprotein.

Thalhammer T, Kieffer LJ, Jiang T, Handschumacher RE.

Eur J Biochem. 1992 May 15;206(1):31-7.

30.
31.

Isolation and characterization of a 40-kDa cyclophilin-related protein.

Kieffer LJ, Thalhammer T, Handschumacher RE.

J Biol Chem. 1992 Mar 15;267(8):5503-7.

32.
33.

Tissue-specific expansion of uridine pools in mice. Effects of benzylacyclouridine, dipyridamole and exogenous uridine.

Darnowski JW, Handschumacher RE, Wiegand RA, Goulette FA, Calabresi P.

Biochem Pharmacol. 1991 Jun 15;41(12):2031-6.

PMID:
2039551
34.

A phase II trial of cyclosporin A in the treatment of refractory metastatic colorectal cancer.

Murren JR, Ganpule S, Sarris A, Durivage H, Davis C, Makuch R, Handschumacher RE, Marsh JC.

Am J Clin Oncol. 1991 Jun;14(3):208-10.

PMID:
2031507
36.

Cyclophilin binding: a more accurate measure of cyclosporine immunosuppressive activity after renal transplantation.

Paul K, Harding MW, Marks WH, Handschumacher RE, Lorber MI.

Transplant Proc. 1991 Feb;23(1 Pt 2):974-5. No abstract available.

PMID:
1989349
37.

Effects of uridine on the growth and differentiation of HL-60 leukemia cells.

Sokoloski JA, Lee CW, Handschumacher RE, Nigam A, Sartorelli AC.

Leuk Res. 1991;15(11):1051-8.

PMID:
1961008
38.

Bradykinin and its Gly6 analogue are substrates of cyclophilin: a fluorine-19 magnetization transfer study.

London RE, Davis DG, Vavrek RJ, Stewart JM, Handschumacher RE.

Biochemistry. 1990 Nov 13;29(45):10298-302.

PMID:
2261473
39.

An overview of recent progress in ligand-receptor research based on nuclear magnetic resonance spectroscopy.

Handschumacher RE, Armitage IM.

Biochem Pharmacol. 1990 Jul 1;40(1):3-5. No abstract available.

PMID:
2372308
40.

Structural elements pertinent to the interaction of cyclosporin A with its specific receptor protein, cyclophilin.

Hsu VL, Heald SL, Harding MW, Handschumacher RE, Armitage IM.

Biochem Pharmacol. 1990 Jul 1;40(1):131-40.

PMID:
2196880
41.

Cyclophilin binding: a receptor-mediated approach to monitoring cyclosporine immunosuppressive activity following organ transplantation.

Lorber MI, Paul K, Harding MW, Handschumacher RE, Marks WH.

Transplant Proc. 1990 Jun;22(3):1240-4. No abstract available.

PMID:
2190386
42.

1H NMR studies on bovine cyclophilin: preliminary structural characterization of its complex with cyclosporin A.

Heald SL, Harding MW, Handschumacher RE, Armitage IM.

Biochemistry. 1990 May 8;29(18):4466-78.

PMID:
2190633
43.

Effect of herpes simplex virus type 1 infection on nucleoside transport in HeLa S3 cells.

PalĂș G, Handschumacher RE, Parolin C, Stefanelli S, Palatini P.

J Gen Virol. 1990 Mar;71 ( Pt 3):673-9.

PMID:
2156000
44.

Enhancement of anthracycline growth inhibition in parent and multidrug-resistant Chinese hamster ovary cells by cyclosporin A and its analogues.

Chambers SK, Hait WN, Kacinski BM, Keyes SR, Handschumacher RE.

Cancer Res. 1989 Nov 15;49(22):6275-9.

45.

Enhancement of fluorouracil therapy by the manipulation of tissue uridine pools.

Darnowski JW, Handschumacher RE.

Pharmacol Ther. 1989;41(1-2):381-92. Review.

PMID:
2652156
46.

Activity of cyclosporin A and a non-immunosuppressive cyclosporin against multidrug resistant leukemic cell lines.

Hait WN, Stein JM, Koletsky AJ, Harding MW, Handschumacher RE.

Cancer Commun. 1989;1(1):35-43.

PMID:
2640154
47.

Cyclophilin, a primary molecular target for cyclosporine. Structural and functional implications.

Harding MW, Handschumacher RE.

Transplantation. 1988 Aug;46(2 Suppl):29S-35S. Review.

PMID:
3043795
48.

Benzylacyclouridine. Pharmacokinetics, metabolism and biochemical effects in mice.

Darnowski JW, Handschumacher RE.

Biochem Pharmacol. 1988 Jul 1;37(13):2613-8.

PMID:
3390221
49.

Cyclosporine--mechanism of action.

Drugge RJ, Handschumacher RE.

Transplant Proc. 1988 Apr;20(2 Suppl 2):301-9. Review. No abstract available.

PMID:
3284073
50.

Concentrative uridine transport by murine splenocytes: kinetics, substrate specificity, and sodium dependency.

Darnowski JW, Holdridge C, Handschumacher RE.

Cancer Res. 1987 May 15;47(10):2614-9.

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