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Items: 1 to 50 of 116


Real-Time Monitoring and Analysis of Zebrafish Electrocardiogram with Anomaly Detection.

Lenning M, Fortunato J, Le T, Clark I, Sherpa A, Yi S, Hofsteen P, Thamilarasu G, Yang J, Xu X, Han HD, Hsiai TK, Cao H.

Sensors (Basel). 2017 Dec 28;18(1). pii: E61. doi: 10.3390/s18010061.


Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.

Noh K, Mangala LS, Han HD, Zhang N, Pradeep S, Wu SY, Ma S, Mora E, Rupaimoole R, Jiang D, Wen Y, Shahzad MMK, Lyons Y, Cho M, Hu W, Nagaraja AS, Haemmerle M, Mak CSL, Chen X, Gharpure KM, Deng H, Xiong W, Kingsley CV, Liu J, Jennings N, Birrer MJ, Bouchard RR, Lopez-Berestein G, Coleman RL, An Z, Sood AK.

Cell Rep. 2017 Dec 5;21(10):2785-2795. doi: 10.1016/j.celrep.2017.11.020.


The status of assisted reproductive technology in Korea in 2012.

Committee for Assisted Reproductive Technology Statistics; Korean Society for Assisted Reproduction, Lee GH, Song HJ, Choi YM, Han HD.

Clin Exp Reprod Med. 2017 Mar;44(1):47-51. doi: 10.5653/cerm.2017.44.1.47. Epub 2017 Mar 31.


Neoagarooligosaccharides prevent septic shock by modulating A20-and cyclooxygenase-2-mediated interleukin-10 secretion in a septic-shock mouse model.

Kang DR, Yoon GY, Cho J, Lee SJ, Lee SJ, Park HJ, Kang TH, Han HD, Park WS, Yoon YK, Park YM, Jung ID.

Biochem Biophys Res Commun. 2017 May 13;486(4):998-1004. doi: 10.1016/j.bbrc.2017.03.152. Epub 2017 Mar 28.


Neoagarohexaose-mediated activation of dendritic cells via Toll-like receptor 4 leads to stimulation of natural killer cells and enhancement of antitumor immunity.

Lee MH, Jang JH, Yoon GY, Lee SJ, Lee MG, Kang TH, Han HD, Kim HS, Choi WS, Park WS, Park YM, Jung ID.

BMB Rep. 2017 May;50(5):263-268.


The C-terminus of IGFBP-5 suppresses tumor growth by inhibiting angiogenesis.

Hwang JR, Cho YJ, Lee Y, Park Y, Han HD, Ahn HJ, Lee JH, Lee JW.

Sci Rep. 2016 Dec 23;6:39334. doi: 10.1038/srep39334.


In vivo stepwise immunomodulation using chitosan nanoparticles as a platform nanotechnology for cancer immunotherapy.

Han HD, Byeon Y, Jang JH, Jeon HN, Kim GH, Kim MG, Pack CG, Kang TH, Jung ID, Lim YT, Lee YJ, Lee JW, Shin BC, Ahn HJ, Sood AK, Park YM.

Sci Rep. 2016 Dec 2;6:38348. doi: 10.1038/srep38348.


Toll-like receptor 3-induced immune response by poly(d,l-lactide-co-glycolide) nanoparticles for dendritic cell-based cancer immunotherapy.

Han HD, Byeon Y, Kang TH, Jung ID, Lee JW, Shin BC, Lee YJ, Sood AK, Park YM.

Int J Nanomedicine. 2016 Nov 2;11:5729-5742. eCollection 2016.


Mycobacterium abscessus D-alanyl-D-alanine dipeptidase induces the maturation of dendritic cells and promotes Th1-biased immunity.

Lee SJ, Jang JH, Yoon GY, Kang DR, Park HJ, Shin SJ, Han HD, Kang TH, Park WS, Yoon YK, Soh BY, Jung ID, Park YM.

BMB Rep. 2016 Oct;49(10):554-559.


Annexin A5 increases survival in murine sepsis model by inhibiting HMGB1-mediated pro-inflammation and coagulation.

Park JH, Jang JH, Choi EJ, Kim YS, Lee EJ, Jung ID, Han HD, Wu TC, Hung CF, Kang TH, Park YM.

Mol Med. 2016 Jul 6;22. doi: 10.2119/molmed.2016.00026. [Epub ahead of print]


FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal.

Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK.

J Clin Invest. 2016 May 2;126(5):1885-96. doi: 10.1172/JCI85086. Epub 2016 Apr 11.


A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer.

Wu SY, Rupaimoole R, Shen F, Pradeep S, Pecot CV, Ivan C, Nagaraja AS, Gharpure KM, Pham E, Hatakeyama H, McGuire MH, Haemmerle M, Vidal-Anaya V, Olsen C, Rodriguez-Aguayo C, Filant J, Ehsanipour EA, Herbrich SM, Maiti SN, Huang L, Kim JH, Zhang X, Han HD, Armaiz-Pena GN, Seviour EG, Tucker S, Zhang M, Yang D, Cooper LJ, Ali-Fehmi R, Bar-Eli M, Lee JS, Ram PT, Baggerly KA, Lopez-Berestein G, Hung MC, Sood AK.

Nat Commun. 2016 Apr 4;7:11169. doi: 10.1038/ncomms11169.


Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma.

Han HD, Cho YJ, Cho SK, Byeon Y, Jeon HN, Kim HS, Kim BG, Bae DS, Lopez-Berestein G, Sood AK, Shin BC, Park YM, Lee JW.

Mol Cancer Ther. 2016 Apr;15(4):618-27. doi: 10.1158/1535-7163.MCT-15-0733-T. Epub 2016 Feb 9.


Marbofloxacin-encapsulated microparticles provide sustained drug release for treatment of veterinary diseases.

Lee J, Kwon HJ, Ji H, Cho SH, Cho EH, Han HD, Shin BC.

Mater Sci Eng C Mater Biol Appl. 2016 Mar;60:511-517. doi: 10.1016/j.msec.2015.12.004. Epub 2015 Dec 4.


Anti-Proliferative and Apoptotic Activities of Müllerian Inhibiting Substance Combined with Calcitriol in Ovarian Cancer Cell Lines.

Jung YS, Kim HJ, Seo SK, Choi YS, Nam EJ, Kim S, Kim SW, Han HD, Kim JW, Kim YT.

Yonsei Med J. 2016 Jan;57(1):33-40. doi: 10.3349/ymj.2016.57.1.33.


Erythropoietin Stimulates Tumor Growth via EphB4.

Pradeep S, Huang J, Mora EM, Nick AM, Cho MS, Wu SY, Noh K, Pecot CV, Rupaimoole R, Stein MA, Brock S, Wen Y, Xiong C, Gharpure K, Hansen JM, Nagaraja AS, Previs RA, Vivas-Mejia P, Han HD, Hu W, Mangala LS, Zand B, Stagg LJ, Ladbury JE, Ozpolat B, Alpay SN, Nishimura M, Stone RL, Matsuo K, Armaiz-Peña GN, Dalton HJ, Danes C, Goodman B, Rodriguez-Aguayo C, Kruger C, Schneider A, Haghpeykar S, Jaladurgam P, Hung MC, Coleman RL, Liu J, Li C, Urbauer D, Lopez-Berestein G, Jackson DB, Sood AK.

Cancer Cell. 2015 Nov 9;28(5):610-622. doi: 10.1016/j.ccell.2015.09.008. Epub 2015 Oct 17.


Pancreatic adenocarcinoma upregulated factor serves as adjuvant by activating dendritic cells through stimulation of TLR4.

Kang TH, Kim YS, Kim S, Yang B, Lee JJ, Lee HJ, Lee J, Jung ID, Han HD, Lee SH, Koh SS, Wu TC, Park YM.

Oncotarget. 2015 Sep 29;6(29):27751-62. doi: 10.18632/oncotarget.4859.


Gold cluster-labeled thermosensitive liposmes enhance triggered drug release in the tumor microenvironment by a photothermal effect.

Kwon HJ, Byeon Y, Jeon HN, Cho SH, Han HD, Shin BC.

J Control Release. 2015 Oct 28;216:132-9. doi: 10.1016/j.jconrel.2015.08.002. Epub 2015 Aug 4.


Therapeutic efficacy of doxorubicin delivery by a CO2 generating liposomal platform in breast carcinoma.

Han HD, Jeon YW, Kwon HJ, Jeon HN, Byeon Y, Lee CO, Cho SH, Shin BC.

Acta Biomater. 2015 Sep;24:279-85. doi: 10.1016/j.actbio.2015.06.019. Epub 2015 Jun 20.


The ZNF304-integrin axis protects against anoikis in cancer.

Aslan B, Monroig P, Hsu MC, Pena GA, Rodriguez-Aguayo C, Gonzalez-Villasana V, Rupaimoole R, Nagaraja AS, Mangala S, Han HD, Yuca E, Wu SY, Ivan C, Moss TJ, Ram PT, Wang H, Gol-Chambers A, Ozkayar O, Kanlikilicer P, Fuentes-Mattei E, Kahraman N, Pradeep S, Ozpolat B, Tucker S, Hung MC, Baggerly K, Bartholomeusz G, Calin G, Sood AK, Lopez-Berestein G.

Nat Commun. 2015 Jun 17;6:7351. doi: 10.1038/ncomms8351.


Copy number gain of hsa-miR-569 at 3q26.2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers.

Chaluvally-Raghavan P, Zhang F, Pradeep S, Hamilton MP, Zhao X, Rupaimoole R, Moss T, Lu Y, Yu S, Pecot CV, Aure MR, Peuget S, Rodriguez-Aguayo C, Han HD, Zhang D, Venkatanarayan A, Krohn M, Kristensen VN, Gagea M, Ram P, Liu W, Lopez-Berestein G, Lorenzi PL, Børresen-Dale AL, Chin K, Gray J, Dusetti NJ, McGuire SE, Flores ER, Sood AK, Mills GB.

Cancer Cell. 2014 Dec 8;26(6):863-879. doi: 10.1016/j.ccell.2014.10.010.


Autocrine stimulation of IL-10 is critical to the enrichment of IL-10-producing CD40(hi)CD5(+) regulatory B cells in vitro and in vivo.

Kim HS, Lee JH, Han HD, Kim AR, Nam ST, Kim HW, Park YH, Lee D, Lee MB, Park YM, Kim HS, Kim YM, You JC, Choi WS.

BMB Rep. 2015 Jan;48(1):54-9.


GM-CSF-loaded chitosan hydrogel as an immunoadjuvant enhances antigen-specific immune responses with reduced toxicity.

Noh KH, Park YM, Kim HS, Kang TH, Song KH, Lee YH, Byeon Y, Jeon HN, Jung ID, Shin BC, Lee KM, Seong SY, Han HD, Kim TW.

BMC Immunol. 2014 Oct 18;15:48. doi: 10.1186/s12865-014-0048-x.


Hematogenous metastasis of ovarian cancer: rethinking mode of spread.

Pradeep S, Kim SW, Wu SY, Nishimura M, Chaluvally-Raghavan P, Miyake T, Pecot CV, Kim SJ, Choi HJ, Bischoff FZ, Mayer JA, Huang L, Nick AM, Hall CS, Rodriguez-Aguayo C, Zand B, Dalton HJ, Arumugam T, Lee HJ, Han HD, Cho MS, Rupaimoole R, Mangala LS, Sehgal V, Oh SC, Liu J, Lee JS, Coleman RL, Ram P, Lopez-Berestein G, Fidler IJ, Sood AK.

Cancer Cell. 2014 Jul 14;26(1):77-91. doi: 10.1016/j.ccr.2014.05.002.


Enhancement of tumor-specific T cell-mediated immunity in dendritic cell-based vaccines by Mycobacterium tuberculosis heat shock protein X.

Jung ID, Shin SJ, Lee MG, Kang TH, Han HD, Lee SJ, Kim WS, Kim HM, Park WS, Kim HW, Yun CH, Lee EK, Wu TC, Park YM.

J Immunol. 2014 Aug 1;193(3):1233-45. doi: 10.4049/jimmunol.1400656. Epub 2014 Jul 2.


Enhanced localization of anticancer drug in tumor tissue using polyethylenimine-conjugated cationic liposomes.

Han HD, Byeon Y, Jeon HN, Shin BC.

Nanoscale Res Lett. 2014 May 5;9(1):209. doi: 10.1186/1556-276X-9-209. eCollection 2014.


API5 confers tumoral immune escape through FGF2-dependent cell survival pathway.

Noh KH, Kim SH, Kim JH, Song KH, Lee YH, Kang TH, Han HD, Sood AK, Ng J, Kim K, Sonn CH, Kumar V, Yee C, Lee KM, Kim TW.

Cancer Res. 2014 Jul 1;74(13):3556-66. doi: 10.1158/0008-5472.CAN-13-3225. Epub 2014 Apr 25.


Metronomic docetaxel in PRINT nanoparticles and EZH2 silencing have synergistic antitumor effect in ovarian cancer.

Gharpure KM, Chu KS, Bowerman CJ, Miyake T, Pradeep S, Mangala SL, Han HD, Rupaimoole R, Armaiz-Pena GN, Rahhal TB, Wu SY, Luft JC, Napier ME, Lopez-Berestein G, DeSimone JM, Sood AK.

Mol Cancer Ther. 2014 Jul;13(7):1750-7. doi: 10.1158/1535-7163.MCT-13-0930. Epub 2014 Apr 22.


Notch3 pathway alterations in ovarian cancer.

Hu W, Liu T, Ivan C, Sun Y, Huang J, Mangala LS, Miyake T, Dalton HJ, Pradeep S, Rupaimoole R, Previs RA, Han HD, Bottsford-Miller J, Zand B, Kang Y, Pecot CV, Nick AM, Wu SY, Lee JS, Sehgal V, Ram P, Liu J, Tucker SL, Lopez-Berestein G, Baggerly KA, Coleman RL, Sood AK.

Cancer Res. 2014 Jun 15;74(12):3282-93. doi: 10.1158/0008-5472.CAN-13-2066. Epub 2014 Apr 17.


Biologic effects of platelet-derived growth factor receptor α blockade in uterine cancer.

Roh JW, Huang J, Hu W, Yang X, Jennings NB, Sehgal V, Sohn BH, Han HD, Lee SJ, Thanapprapasr D, Bottsford-Miller J, Zand B, Dalton HJ, Previs RA, Davis AN, Matsuo K, Lee JS, Ram P, Coleman RL, Sood AK.

Clin Cancer Res. 2014 May 15;20(10):2740-50. doi: 10.1158/1078-0432.CCR-13-2507. Epub 2014 Mar 14.


2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity.

Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, Previs RA, Armaiz-Pena GN, Huang L, Martinez C, Hassell T, Ivan C, Sehgal V, Singhania R, Han HD, Su C, Kim JH, Dalton HJ, Kovvali C, Keyomarsi K, McMillan NA, Overwijk WW, Liu J, Lee JS, Baggerly KA, Lopez-Berestein G, Ram PT, Nawrot B, Sood AK.

Nat Commun. 2014 Mar 12;5:3459. doi: 10.1038/ncomms4459.


Autocrine effects of tumor-derived complement.

Cho MS, Vasquez HG, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Rodriguez-Aguayo C, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Baggerly K, Lopez-Berestein G, Sood AK, Afshar-Kharghan V.

Cell Rep. 2014 Mar 27;6(6):1085-1095. doi: 10.1016/j.celrep.2014.02.014. Epub 2014 Mar 6.


Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib.

Huang J, Hu W, Bottsford-Miller J, Liu T, Han HD, Zand B, Pradeep S, Roh JW, Thanapprapasr D, Dalton HJ, Pecot CV, Rupaimoole R, Lu C, Fellman B, Urbauer D, Kang Y, Jennings NB, Huang L, Deavers MT, Broaddus R, Coleman RL, Sood AK.

Clin Cancer Res. 2014 Apr 1;20(7):1846-55. doi: 10.1158/1078-0432.CCR-13-2141. Epub 2014 Jan 31.


[A new eremophilane derivative from Senecio dianthus].

Han HD, Hu HQ, Li Y, Wang XL.

Zhongguo Zhong Yao Za Zhi. 2013 Oct;38(19):3295-8. Chinese.


Current status of assisted reproductive technology in Korea, 2009.

Committee for Assisted Reproductive Technology, Korean Society of Obstetrics and Gynecology, Choi YM, Chun SS, Han HD, Hwang JH, Hwang KJ, Kang IS, Kim DW, Kim KC, Kim T, Kwon HC, Lee WD, Lee JH, Lee KS, Lee GH, Lee SH, Lee YI, Min EG, Moon HS, Moon SY, Roh SI, Yoon TK.

Obstet Gynecol Sci. 2013 Nov;56(6):353-61. doi: 10.5468/ogs.2013.56.6.353. Epub 2013 Nov 15. Review.


The Mycobacterium avium subsp. Paratuberculosis protein MAP1305 modulates dendritic cell-mediated T cell proliferation through Toll-like receptor-4.

Lee SJ, Noh KT, Kang TH, Han HD, Shin SJ, Soh BY, Park JH, Shin YK, Kim HW, Yun CH, Park WS, Jung ID, Park YM.

BMB Rep. 2014 Feb;47(2):115-20.


[Chemical constituents of Paederia pertomentosa].

Hu HQ, Han HD, Lin Y, Chen LH, Wang XL.

Zhongguo Zhong Yao Za Zhi. 2013 Aug;38(16):2657-60. Chinese.


Nanoparticle-based vaccine delivery for cancer immunotherapy.

Park YM, Lee SJ, Kim YS, Lee MH, Cha GS, Jung ID, Kang TH, Han HD.

Immune Netw. 2013 Oct;13(5):177-83. doi: 10.4110/in.2013.13.5.177. Epub 2013 Oct 26. Review.


Therapeutic Silencing of Bcl-2 by Systemically Administered siRNA Nanotherapeutics Inhibits Tumor Growth by Autophagy and Apoptosis and Enhances the Efficacy of Chemotherapy in Orthotopic Xenograft Models of ER (-) and ER (+) Breast Cancer.

Tekedereli I, Alpay SN, Akar U, Yuca E, Ayugo-Rodriguez C, Han HD, Sood AK, Lopez-Berestein G, Ozpolat B.

Mol Ther Nucleic Acids. 2013 Sep 10;2:e121. doi: 10.1038/mtna.2013.45.


Tumour angiogenesis regulation by the miR-200 family.

Pecot CV, Rupaimoole R, Yang D, Akbani R, Ivan C, Lu C, Wu S, Han HD, Shah MY, Rodriguez-Aguayo C, Bottsford-Miller J, Liu Y, Kim SB, Unruh A, Gonzalez-Villasana V, Huang L, Zand B, Moreno-Smith M, Mangala LS, Taylor M, Dalton HJ, Sehgal V, Wen Y, Kang Y, Baggerly KA, Lee JS, Ram PT, Ravoori MK, Kundra V, Zhang X, Ali-Fehmi R, Gonzalez-Angulo AM, Massion PP, Calin GA, Lopez-Berestein G, Zhang W, Sood AK.

Nat Commun. 2013;4:2427. doi: 10.1038/ncomms3427.


Therapeutic synergy between microRNA and siRNA in ovarian cancer treatment.

Nishimura M, Jung EJ, Shah MY, Lu C, Spizzo R, Shimizu M, Han HD, Ivan C, Rossi S, Zhang X, Nicoloso MS, Wu SY, Almeida MI, Bottsford-Miller J, Pecot CV, Zand B, Matsuo K, Shahzad MM, Jennings NB, Rodriguez-Aguayo C, Lopez-Berestein G, Sood AK, Calin GA.

Cancer Discov. 2013 Nov;3(11):1302-15. doi: 10.1158/2159-8290.CD-13-0159. Epub 2013 Sep 3.


Mesonephric Adenocarcinoma of the Uterine Cervix Associated with Florid Mesonephric Hyperplasia: A Case Report.

Abdul-Ghafar J, Chong Y, Han HD, Cha DS, Eom M.

J Lifestyle Med. 2013 Sep;3(2):117-20. Epub 2013 Sep 30.


A core human primary tumor angiogenesis signature identifies the endothelial orphan receptor ELTD1 as a key regulator of angiogenesis.

Masiero M, Simões FC, Han HD, Snell C, Peterkin T, Bridges E, Mangala LS, Wu SY, Pradeep S, Li D, Han C, Dalton H, Lopez-Berestein G, Tuynman JB, Mortensen N, Li JL, Patient R, Sood AK, Banham AH, Harris AL, Buffa FM.

Cancer Cell. 2013 Aug 12;24(2):229-41. doi: 10.1016/j.ccr.2013.06.004. Epub 2013 Jul 18.


Effect of physiological posterolateral rotatory laxity on early results of posterior cruciate ligament reconstruction with posterolateral corner reconstruction.

Kim SJ, Kim SG, Lee IS, Han HD, Chung IH, Kim SH, Gorthi V.

J Bone Joint Surg Am. 2013 Jul 3;95(13):1222-7. doi: 10.2106/JBJS.L.00861.


Performance after timely cochlear implantation in prelingually deaf children with cerebral palsy.

Byun H, Moon IJ, Kim EY, Park J, Kwon SY, Han HD, Chung WH, Cho YS, Hong SH.

Int J Pediatr Otorhinolaryngol. 2013 Jun;77(6):1013-8. doi: 10.1016/j.ijporl.2013.03.034. Epub 2013 Apr 29.


Biologic effects of dopamine on tumor vasculature in ovarian carcinoma.

Moreno-Smith M, Lee SJ, Lu C, Nagaraja AS, He G, Rupaimoole R, Han HD, Jennings NB, Roh JW, Nishimura M, Kang Y, Allen JK, Armaiz GN, Matsuo K, Shahzad MM, Bottsford-Miller J, Langley RR, Cole SW, Lutgendorf SK, Siddik ZH, Sood AK.

Neoplasia. 2013 May;15(5):502-10.


Tat-activating regulatory DNA-binding protein regulates glycolysis in hepatocellular carcinoma by regulating the platelet isoform of phosphofructokinase through microRNA 520.

Park YY, Kim SB, Han HD, Sohn BH, Kim JH, Liang J, Lu Y, Rodriguez-Aguayo C, Lopez-Berestein G, Mills GB, Sood AK, Lee JS.

Hepatology. 2013 Jul;58(1):182-91. doi: 10.1002/hep.26310. Epub 2013 May 15.


Enhancing chemotherapy response with sustained EphA2 silencing using multistage vector delivery.

Shen H, Rodriguez-Aguayo C, Xu R, Gonzalez-Villasana V, Mai J, Huang Y, Zhang G, Guo X, Bai L, Qin G, Deng X, Li Q, Erm DR, Aslan B, Liu X, Sakamoto J, Chavez-Reyes A, Han HD, Sood AK, Ferrari M, Lopez-Berestein G.

Clin Cancer Res. 2013 Apr 1;19(7):1806-15. doi: 10.1158/1078-0432.CCR-12-2764. Epub 2013 Feb 5.


Endoglin (CD105) contributes to platinum resistance and is a target for tumor-specific therapy in epithelial ovarian cancer.

Ziebarth AJ, Nowsheen S, Steg AD, Shah MM, Katre AA, Dobbin ZC, Han HD, Lopez-Berestein G, Sood AK, Conner M, Yang ES, Landen CN.

Clin Cancer Res. 2013 Jan 1;19(1):170-82. doi: 10.1158/1078-0432.CCR-12-1045. Epub 2012 Nov 12.

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