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Items: 5


Differential regulation of detoxification enzymes in hepatic and mammary tissue by hops (Humulus lupulus) in vitro and in vivo.

Dietz BM, Hagos GK, Eskra JN, Wijewickrama GT, Anderson JR, Nikolic D, Guo J, Wright B, Chen SN, Pauli GF, van Breemen RB, Bolton JL.

Mol Nutr Food Res. 2013 Jun;57(6):1055-66. doi: 10.1002/mnfr.201200534. Epub 2013 Mar 20.


Angelica sinensis and its alkylphthalides induce the detoxification enzyme NAD(P)H: quinone oxidoreductase 1 by alkylating Keap1.

Dietz BM, Liu D, Hagos GK, Yao P, Schinkovitz A, Pro SM, Deng S, Farnsworth NR, Pauli GF, van Breemen RB, Bolton JL.

Chem Res Toxicol. 2008 Oct;21(10):1939-48. doi: 10.1021/tx8001274. Epub 2008 Sep 23.


Anti-inflammatory, antiproliferative, and cytoprotective activity of NO chimera nitrates of use in cancer chemoprevention.

Hagos GK, Abdul-Hay SO, Sohn J, Edirisinghe PD, Chandrasena RE, Wang Z, Li Q, Thatcher GR.

Mol Pharmacol. 2008 Nov;74(5):1381-91. doi: 10.1124/mol.108.046664. Epub 2008 Aug 1.


Nitrates and NO-NSAIDs in cancer chemoprevention and therapy: in vitro evidence querying the NO donor functionality.

Dunlap T, Abdul-Hay SO, Chandrasena RE, Hagos GK, Sinha V, Wang Z, Wang H, Thatcher GR.

Nitric Oxide. 2008 Sep;19(2):115-24. doi: 10.1016/j.niox.2008.04.013. Epub 2008 Apr 23.


Colon cancer chemoprevention by a novel NO chimera that shows anti-inflammatory and antiproliferative activity in vitro and in vivo.

Hagos GK, Carroll RE, Kouznetsova T, Li Q, Toader V, Fernandez PA, Swanson SM, Thatcher GR.

Mol Cancer Ther. 2007 Aug;6(8):2230-9.

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