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Items: 1 to 50 of 161

1.

Diagnostic of students' misconceptions using the Biological Concepts Instrument (BCI): A method for conducting an educational needs assessment.

Champagne Queloz A, Klymkowsky MW, Stern E, Hafen E, Köhler K.

PLoS One. 2017 May 11;12(5):e0176906. doi: 10.1371/journal.pone.0176906. eCollection 2017.

2.

Analysis of novel alleles of brother of tout-velu, the drosophila ortholog of human EXTL3 using a newly developed FRT42D ovoD chromosome.

Lujan E, Bornemann DJ, Rottig C, Bayless BA, Stocker H, Hafen E, Arora K, Warrior R.

Genesis. 2016 Nov;54(11):573-581. doi: 10.1002/dvg.22981. Epub 2016 Oct 3.

3.

Proteome-wide association studies identify biochemical modules associated with a wing-size phenotype in Drosophila melanogaster.

Okada H, Ebhardt HA, Vonesch SC, Aebersold R, Hafen E.

Nat Commun. 2016 Sep 1;7:12649. doi: 10.1038/ncomms12649.

4.

Attitudes towards personal genomics among older Swiss adults: An exploratory study.

Mählmann L, Röcke C, Brand A, Hafen E, Vayena E.

Appl Transl Genom. 2016 Feb 1;8:9-15. doi: 10.1016/j.atg.2016.01.009. eCollection 2016 Mar.

5.

Genome-Wide Analysis Reveals Novel Regulators of Growth in Drosophila melanogaster.

Vonesch SC, Lamparter D, Mackay TF, Bergmann S, Hafen E.

PLoS Genet. 2016 Jan 11;12(1):e1005616. doi: 10.1371/journal.pgen.1005616. eCollection 2016 Jan.

6.

TORC2 mediates the heat stress response in Drosophila by promoting the formation of stress granules.

Jevtov I, Zacharogianni M, van Oorschot MM, van Zadelhoff G, Aguilera-Gomez A, Vuillez I, Braakman I, Hafen E, Stocker H, Rabouille C.

J Cell Sci. 2015 Jul 15;128(14):2497-508. doi: 10.1242/jcs.168724. Epub 2015 Jun 8.

7.

Multi-functional regulation of 4E-BP gene expression by the Ccr4-Not complex.

Okada H, Schittenhelm RB, Straessle A, Hafen E.

PLoS One. 2015 Mar 20;10(3):e0113902. doi: 10.1371/journal.pone.0113902. eCollection 2015.

8.

The FlyCatwalk: a high-throughput feature-based sorting system for artificial selection in Drosophila.

Medici V, Vonesch SC, Fry SN, Hafen E.

G3 (Bethesda). 2015 Jan 2;5(3):317-27. doi: 10.1534/g3.114.013664.

9.

Towards long term cultivation of Drosophila wing imaginal discs in vitro.

Handke B, Szabad J, Lidsky PV, Hafen E, Lehner CF.

PLoS One. 2014 Sep 9;9(9):e107333. doi: 10.1371/journal.pone.0107333. eCollection 2014.

10.

Playing a part in research? University students' attitudes to direct-to-consumer genomics.

Vayena E, Ineichen C, Stoupka E, Hafen E.

Public Health Genomics. 2014;17(3):158-68. doi: 10.1159/000360257. Epub 2014 Apr 25.

11.

Bernard Lerer: recipient of the 2014 inaugural Werner Kalow Responsible Innovation Prize in Global Omics and Personalized Medicine (Pacific Rim Association for Clinical Pharmacogenetics).

Ozdemir V, Endrenyi L, Aynacıoğlu S, Bragazzi NL, Dandara C, Dove ES, Ferguson LR, Geraci CJ, Hafen E, Kesim BE, Kolker E, Lee EJ, Llerena A, Nacak M, Shimoda K, Someya T, Srivastava S, Tomlinson B, Vayena E, Warnich L, Yaşar U.

OMICS. 2014 Apr;18(4):211-21. doi: 10.1089/omi.2014.0029. Epub 2014 Mar 20.

12.

Health data cooperatives - citizen empowerment.

Hafen E, Kossmann D, Brand A.

Methods Inf Med. 2014;53(2):82-6. doi: 10.3414/ME13-02-0051. Epub 2014 Feb 11.

PMID:
24514946
13.

The RNA-binding proteins FMR1, rasputin and caprin act together with the UBA protein lingerer to restrict tissue growth in Drosophila melanogaster.

Baumgartner R, Stocker H, Hafen E.

PLoS Genet. 2013;9(7):e1003598. doi: 10.1371/journal.pgen.1003598. Epub 2013 Jul 11.

14.

Nutrient restriction enhances the proliferative potential of cells lacking the tumor suppressor PTEN in mitotic tissues.

Nowak K, Seisenbacher G, Hafen E, Stocker H.

Elife. 2013 Jul 9;2:e00380. doi: 10.7554/eLife.00380.

15.

The hemolymph proteome of fed and starved Drosophila larvae.

Handke B, Poernbacher I, Goetze S, Ahrens CH, Omasits U, Marty F, Simigdala N, Meyer I, Wollscheid B, Brunner E, Hafen E, Lehner CF.

PLoS One. 2013 Jun 20;8(6):e67208. doi: 10.1371/journal.pone.0067208. Print 2013.

16.

Local requirement of the Drosophila insulin binding protein imp-L2 in coordinating developmental progression with nutritional conditions.

Sarraf-Zadeh L, Christen S, Sauer U, Cognigni P, Miguel-Aliaga I, Stocker H, Köhler K, Hafen E.

Dev Biol. 2013 Sep 1;381(1):97-106. doi: 10.1016/j.ydbio.2013.06.008. Epub 2013 Jun 15.

17.

The IGFBP7 homolog Imp-L2 promotes insulin signaling in distinct neurons of the Drosophila brain.

Bader R, Sarraf-Zadeh L, Peters M, Moderau N, Stocker H, Köhler K, Pankratz MJ, Hafen E.

J Cell Sci. 2013 Jun 15;126(Pt 12):2571-6. doi: 10.1242/jcs.120261. Epub 2013 Apr 16.

18.

The Lnk/SH2B adaptor provides a fail-safe mechanism to establish the Insulin receptor-Chico interaction.

Almudi I, Poernbacher I, Hafen E, Stocker H.

Cell Commun Signal. 2013 Apr 16;11(1):26. doi: 10.1186/1478-811X-11-26.

19.

Biochemical membrane lipidomics during Drosophila development.

Guan XL, Cestra G, Shui G, Kuhrs A, Schittenhelm RB, Hafen E, van der Goot FG, Robinett CC, Gatti M, Gonzalez-Gaitan M, Wenk MR.

Dev Cell. 2013 Jan 14;24(1):98-111. doi: 10.1016/j.devcel.2012.11.012. Epub 2012 Dec 20.

20.

Use of anionic denaturing detergents to purify insoluble proteins after overexpression.

Schlager B, Straessle A, Hafen E.

BMC Biotechnol. 2012 Dec 11;12:95. doi: 10.1186/1472-6750-12-95.

21.

The lack of autophagy triggers precocious activation of Notch signaling during Drosophila oogenesis.

Barth JM, Hafen E, Köhler K.

BMC Dev Biol. 2012 Dec 5;12:35. doi: 10.1186/1471-213X-12-35.

22.

Experiences of early users of direct-to-consumer genomics in Switzerland: an exploratory study.

Vayena E, Gourna E, Streuli J, Hafen E, Prainsack B.

Public Health Genomics. 2012;15(6):352-62. doi: 10.1159/000343792. Epub 2012 Nov 15.

23.

[Genome analysis - what does the future hold, what is science fiction? Interview by Prof. Dr. med. Johann Steurer].

Hafen E, Roose A.

Praxis (Bern 1994). 2012 Jul 25;101(15):971-4. doi: 10.1024/1661-8157/a001010. German. No abstract available.

PMID:
22811330
24.

Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.

Glatter T, Schittenhelm RB, Rinner O, Roguska K, Wepf A, Jünger MA, Köhler K, Jevtov I, Choi H, Schmidt A, Nesvizhskii AI, Stocker H, Hafen E, Aebersold R, Gstaiger M.

Mol Syst Biol. 2011 Nov 8;7:547. doi: 10.1038/msb.2011.79.

25.

MK2-dependent p38b signalling protects Drosophila hindgut enterocytes against JNK-induced apoptosis under chronic stress.

Seisenbacher G, Hafen E, Stocker H.

PLoS Genet. 2011 Aug;7(8):e1002168. doi: 10.1371/journal.pgen.1002168. Epub 2011 Aug 4.

26.

Substrate-dependent control of MAPK phosphorylation in vivo.

Kim Y, Paroush Z, Nairz K, Hafen E, Jiménez G, Shvartsman SY.

Mol Syst Biol. 2011 Feb 1;7:467. doi: 10.1038/msb.2010.121.

27.

Autophagy in Drosophila ovaries is induced by starvation and is required for oogenesis.

Barth JM, Szabad J, Hafen E, Köhler K.

Cell Death Differ. 2011 Jun;18(6):915-24. doi: 10.1038/cdd.2010.157. Epub 2010 Dec 10.

28.

The nuclear receptor DHR3 modulates dS6 kinase-dependent growth in Drosophila.

Montagne J, Lecerf C, Parvy JP, Bennion JM, Radimerski T, Ruhf ML, Zilbermann F, Vouilloz N, Stocker H, Hafen E, Kozma SC, Thomas G.

PLoS Genet. 2010 May 6;6(5):e1000937. doi: 10.1371/journal.pgen.1000937.

29.

Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk.

Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L.

PLoS Genet. 2010 Mar 19;6(3):e1000881. doi: 10.1371/journal.pgen.1000881.

30.

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

Baumgartner R, Poernbacher I, Buser N, Hafen E, Stocker H.

Dev Cell. 2010 Feb 16;18(2):309-16. doi: 10.1016/j.devcel.2009.12.013.

31.

Madm (Mlf1 adapter molecule) cooperates with Bunched A to promote growth in Drosophila.

Gluderer S, Brunner E, Germann M, Jovaisaite V, Li C, Rentsch CA, Hafen E, Stocker H.

J Biol. 2010;9(1):9. doi: 10.1186/jbiol216. Epub 2010 Feb 11.

32.

Exploring the effects of mechanical feedback on epithelial topology.

Aegerter-Wilmsen T, Smith AC, Christen AJ, Aegerter CM, Hafen E, Basler K.

Development. 2010 Feb;137(3):499-506. doi: 10.1242/dev.041731.

33.

Identification and functional characterization of N-terminally acetylated proteins in Drosophila melanogaster.

Goetze S, Qeli E, Mosimann C, Staes A, Gerrits B, Roschitzki B, Mohanty S, Niederer EM, Laczko E, Timmerman E, Lange V, Hafen E, Aebersold R, Vandekerckhove J, Basler K, Ahrens CH, Gevaert K, Brunner E.

PLoS Biol. 2009 Nov;7(11):e1000236. doi: 10.1371/journal.pbio.1000236. Epub 2009 Nov 3.

34.

The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway.

Werz C, Köhler K, Hafen E, Stocker H.

PLoS Genet. 2009 Aug;5(8):e1000596. doi: 10.1371/journal.pgen.1000596. Epub 2009 Aug 14.

35.

A combined proteomic and genetic analysis identifies a role for the lipid desaturase Desat1 in starvation-induced autophagy in Drosophila.

Köhler K, Brunner E, Guan XL, Boucke K, Greber UF, Mohanty S, Barth JM, Wenk MR, Hafen E.

Autophagy. 2009 Oct;5(7):980-90. Epub 2009 Oct 22.

PMID:
19587536
36.

Pushing single-gene genetic analysis up a Notch.

Hafen E.

Dev Cell. 2009 May;16(5):623-4. doi: 10.1016/j.devcel.2009.05.006.

37.

The Drosophila melanogaster PeptideAtlas facilitates the use of peptide data for improved fly proteomics and genome annotation.

Loevenich SN, Brunner E, King NL, Deutsch EW, Stein SE; FlyBase Consortium, Aebersold R, Hafen E.

BMC Bioinformatics. 2009 Feb 11;10:59. doi: 10.1186/1471-2105-10-59.

38.

SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development.

Almudi I, Stocker H, Hafen E, Corominas M, Serras F.

Dev Biol. 2009 Feb 1;326(1):212-23. doi: 10.1016/j.ydbio.2008.11.014. Epub 2008 Nov 30.

39.

Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs.

Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L.

PLoS One. 2008;3(11):e3721. doi: 10.1371/journal.pone.0003721. Epub 2008 Nov 13.

40.

A proteome catalog of Drosophila melanogaster: an essential resource for targeted quantitative proteomics.

Ahrens CH, Brunner E, Hafen E, Aebersold R, Basler K.

Fly (Austin). 2007 May-Jun;1(3):182-6. Epub 2007 May 4.

PMID:
18820430
41.

Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance.

Honegger B, Galic M, Köhler K, Wittwer F, Brogiolo W, Hafen E, Stocker H.

J Biol. 2008;7(3):10. doi: 10.1186/jbiol72. Epub 2008 Apr 15.

42.

The Drosophila homolog of human tumor suppressor TSC-22 promotes cellular growth, proliferation, and survival.

Wu X, Yamada-Mabuchi M, Morris EJ, Tanwar PS, Dobens L, Gluderer S, Khan S, Cao J, Stocker H, Hafen E, Dyson NJ, Raftery LA.

Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5414-9. doi: 10.1073/pnas.0800945105. Epub 2008 Mar 28.

43.

Drosophila egg-laying site selection as a system to study simple decision-making processes.

Yang CH, Belawat P, Hafen E, Jan LY, Jan YN.

Science. 2008 Mar 21;319(5870):1679-83. doi: 10.1126/science.1151842.

44.

Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth.

Gluderer S, Oldham S, Rintelen F, Sulzer A, Schütt C, Wu X, Raftery LA, Hafen E, Stocker H.

BMC Dev Biol. 2008 Jan 28;8:10. doi: 10.1186/1471-213X-8-10.

45.

Drosophila cbl is essential for control of cell death and cell differentiation during eye development.

Wang Y, Werz C, Xu D, Chen Z, Li Y, Hafen E, Bergmann A.

PLoS One. 2008 Jan 16;3(1):e1447. doi: 10.1371/journal.pone.0001447.

46.

The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource.

Ryder E, Ashburner M, Bautista-Llacer R, Drummond J, Webster J, Johnson G, Morley T, Chan YS, Blows F, Coulson D, Reuter G, Baisch H, Apelt C, Kauk A, Rudolph T, Kube M, Klimm M, Nickel C, Szidonya J, Maróy P, Pal M, Rasmuson-Lestander A, Ekström K, Stocker H, Hugentobler C, Hafen E, Gubb D, Pflugfelder G, Dorner C, Mechler B, Schenkel H, Marhold J, Serras F, Corominas M, Punset A, Roote J, Russell S.

Genetics. 2007 Sep;177(1):615-29. Epub 2007 Aug 24.

47.

Connecting up the pathways in Drosophila development.

Riesgo-Escovar JR, Hafen E, Hou XS, Goldstein ES, Perrimon N, Glise B, Noselli S, Kockel L, Zeitlinger J, Staszewski LM, Mlodzik M, Bohmann D.

Trends Cell Biol. 1997 Nov;7(11):421-2. No abstract available.

PMID:
17708993
48.

A high-quality catalog of the Drosophila melanogaster proteome.

Brunner E, Ahrens CH, Mohanty S, Baetschmann H, Loevenich S, Potthast F, Deutsch EW, Panse C, de Lichtenberg U, Rinner O, Lee H, Pedrioli PG, Malmstrom J, Koehler K, Schrimpf S, Krijgsveld J, Kregenow F, Heck AJ, Hafen E, Schlapbach R, Aebersold R.

Nat Biotechnol. 2007 May;25(5):576-83. Epub 2007 Apr 22.

PMID:
17450130
49.

Model for the regulation of size in the wing imaginal disc of Drosophila.

Aegerter-Wilmsen T, Aegerter CM, Hafen E, Basler K.

Mech Dev. 2007 Apr;124(4):318-26. Epub 2006 Dec 29.

50.

The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye.

Sesé M, Corominas M, Stocker H, Heino TI, Hafen E, Serras F.

J Cell Sci. 2006 Dec 15;119(Pt 24):5047-56. Epub 2006 Nov 21.

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