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Items: 1 to 50 of 443

1.

APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.

Oveisgharan S, Buchman AS, Yu L, Farfel J, Hachinski V, Gaiteri C, De Jager PL, Schneider JA, Bennett DA.

Neurology. 2018 May 11. pii: 10.1212/WNL.0000000000005677. doi: 10.1212/WNL.0000000000005677. [Epub ahead of print]

PMID:
29752306
2.

B Vitamins for Stroke Prevention: Interaction of Low Platelet Count and High Plasma Total Homocysteine.

Spence JD, Hachinski V.

J Am Coll Cardiol. 2018 May 15;71(19):2147-2148. doi: 10.1016/j.jacc.2018.03.024. No abstract available.

PMID:
29747835
3.

Cognitive changes following multiple-modality exercise and mind-motor training in older adults with subjective cognitive complaints: The M4 study.

Boa Sorte Silva NC, Gill DP, Owen AM, Liu-Ambrose T, Hachinski V, Shigematsu R, Petrella RJ.

PLoS One. 2018 Apr 26;13(4):e0196356. doi: 10.1371/journal.pone.0196356. eCollection 2018.

4.

Motor and Cognitive Trajectories Before Dementia: Results from Gait and Brain Study.

Montero-Odasso M, Speechley M, Muir-Hunter SW, Sarquis-Adamson Y, Sposato LA, Hachinski V, Borrie M, Wells J, Black A, Sejdić E, Bherer L, Chertkow H; Canadian Gait and Cognition Network.

J Am Geriatr Soc. 2018 Apr 2. doi: 10.1111/jgs.15341. [Epub ahead of print]

PMID:
29608780
5.

Author response: Upgoing thumb sign: A sensitive indicator of brain involvement?

Hachinski V, Alsubaie R, Azarpazhooh MR.

Neurology. 2018 Feb 20;90(8):394-395. doi: 10.1212/WNL.0000000000004990. No abstract available.

PMID:
29459452
6.

The upgoing thumb sign: An interobserver/intraobserver reliability study.

Abootalebi S, Azarpazhooh MR, Sposato L, Hachinski V.

Neurol Clin Pract. 2017 Dec;7(6):483-487. doi: 10.1212/CPJ.0000000000000398.

PMID:
29431171
7.

Cerebrovascular and Alzheimer disease: fellow travelers or partners in crime?

Nucera A, Hachinski V.

J Neurochem. 2018 Mar;144(5):513-516. doi: 10.1111/jnc.14283. Epub 2018 Jan 25. Review.

PMID:
29266273
8.

Inhibition of the primary motor cortex and the upgoing thumb sign.

Nucera A, Azarpazhooh MR, Cardinali L, Alsubaie R, Chiang TC, Weishaupt N, Hachinski V.

eNeurologicalSci. 2017 Jul 19;8:31-33. doi: 10.1016/j.ensci.2017.07.001. eCollection 2017 Sep.

9.

The vascular facet of late-onset Alzheimer's disease: an essential factor in a complex multifactorial disorder.

Iturria-Medina Y, Hachinski V, Evans AC.

Curr Opin Neurol. 2017 Dec;30(6):623-629. doi: 10.1097/WCO.0000000000000497.

PMID:
29095718
10.

Blood pressure at age 60-65 versus age 70-75 and vascular dementia: a population based observational study.

Peng M, Chen G, Tang KL, Quan H, Smith EE, Faris P, Hachinski V, Campbell NRC.

BMC Geriatr. 2017 Oct 27;17(1):252. doi: 10.1186/s12877-017-0649-3.

11.

Concomitant vascular and neurodegenerative pathologies double the risk of dementia.

Azarpazhooh MR, Avan A, Cipriano LE, Munoz DG, Sposato LA, Hachinski V.

Alzheimers Dement. 2018 Feb;14(2):148-156. doi: 10.1016/j.jalz.2017.07.755. Epub 2017 Sep 30.

PMID:
28974416
12.

Time is brain: Balancing risk in the treatment of presumed cardioembolic stroke.

Nucera A, Azarpazhooh MR, Alsubaie R, Riccio P, Hachinski V.

J Neurol Sci. 2017 Nov 15;382:157-160. doi: 10.1016/j.jns.2017.07.022. Epub 2017 Jul 21.

PMID:
28778583
13.

Comprehensive Cardiac Rehabilitation for Secondary Prevention After Transient Ischemic Attack or Mild Stroke: PSYCHOLOGICAL PROFILE AND OUTCOMES.

Prior PL, Hachinski V, Chan R, Unsworth K, Mytka S, Harnadek M, OʼCallaghan C, Suskin N.

J Cardiopulm Rehabil Prev. 2017 Nov;37(6):428-436. doi: 10.1097/HCR.0000000000000274.

PMID:
28727668
14.

Behavioural inflexibility in a comorbid rat model of striatal ischemic injury and mutant hAPP overexpression.

Levit A, Regis AM, Garabon JR, Oh SH, Desai SJ, Rajakumar N, Hachinski V, Agca Y, Agca C, Whitehead SN, Allman BL.

Behav Brain Res. 2017 Aug 30;333:267-275. doi: 10.1016/j.bbr.2017.07.006. Epub 2017 Jul 8.

PMID:
28693862
15.

Upgoing thumb sign: A sensitive indicator of brain involvement?

Hachinski V, Alsubaie R, Azarpazhooh MR.

Neurology. 2017 Jul 25;89(4):370-375. doi: 10.1212/WNL.0000000000004157. Epub 2017 Jun 28. Erratum in: Neurology. 2018 Feb 20;90(8):396.

PMID:
28659430
16.

Association of Dual-Task Gait With Incident Dementia in Mild Cognitive Impairment: Results From the Gait and Brain Study.

Montero-Odasso MM, Sarquis-Adamson Y, Speechley M, Borrie MJ, Hachinski VC, Wells J, Riccio PM, Schapira M, Sejdic E, Camicioli RM, Bartha R, McIlroy WE, Muir-Hunter S.

JAMA Neurol. 2017 Jul 1;74(7):857-865. doi: 10.1001/jamaneurol.2017.0643.

PMID:
28505243
17.

Therapeutic Strategies and Drug Development for Vascular Cognitive Impairment.

Smith EE, Cieslak A, Barber P, Chen J, Chen YW, Donnini I, Edwards JD, Frayne R, Field TS, Hegedus J, Hanganu V, Ismail Z, Kanji J, Nakajima M, Noor R, Peca S, Sahlas D, Sharma M, Sposato LA, Swartz RH, Zerna C, Black SE, Hachinski V.

J Am Heart Assoc. 2017 May 5;6(5). pii: e005568. doi: 10.1161/JAHA.117.005568. Review. No abstract available.

18.

Stoop to conquer: preventing stroke and dementia together.

Hachinski V.

Lancet. 2017 Apr 15;389(10078):1518. doi: 10.1016/S0140-6736(17)30954-6. No abstract available.

PMID:
28422027
19.

Optimisation of stroke research.

Azarpazhooh MR, Hachinski V.

Lancet Neurol. 2017 May;16(5):340-341. doi: 10.1016/S1474-4422(17)30081-9. No abstract available.

PMID:
28414643
20.

Does left ventricular hypertrophy affect cognition and brain structural integrity in type 2 diabetes? Study design and rationale of the Diabetes and Dementia (D2) study.

Patel SK, Restrepo C, Werden E, Churilov L, Ekinci EI, Srivastava PM, Ramchand J, Wai B, Chambers B, O'Callaghan CJ, Darby D, Hachinski V, Cumming T, Donnan G, Burrell LM, Brodtmann A.

BMC Endocr Disord. 2017 Apr 7;17(1):24. doi: 10.1186/s12902-017-0173-7.

21.

Potential Value of Impaired Cognition in Stroke Prediction: A U.K. Population-Based Study.

Stephan BCM, Richardson K, Savva GM, Matthews FE, Brayne C, Hachinski V.

J Am Geriatr Soc. 2017 Aug;65(8):1756-1762. doi: 10.1111/jgs.14878. Epub 2017 Apr 3.

22.

Population-based stroke and dementia incidence trends: Age and sex variations.

Cerasuolo JO, Cipriano LE, Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Hachinski V.

Alzheimers Dement. 2017 Oct;13(10):1081-1088. doi: 10.1016/j.jalz.2017.02.010. Epub 2017 Mar 28.

PMID:
28363085
23.

Combined Dual-Task Gait Training and Aerobic Exercise to Improve Cognition, Mobility, and Vascular Health in Community-Dwelling Older Adults at Risk for Future Cognitive Decline1.

Gregory MA, Boa Sorte Silva NC, Gill DP, McGowan CL, Liu-Ambrose T, Shoemaker JK, Hachinski V, Holmes J, Petrella RJ.

J Alzheimers Dis. 2017;57(3):747-763. doi: 10.3233/JAD-161240.

PMID:
28304305
24.

Cost-effectiveness of cerebrospinal biomarkers for the diagnosis of Alzheimer's disease.

Lee SA, Sposato LA, Hachinski V, Cipriano LE.

Alzheimers Res Ther. 2017 Mar 16;9(1):18. doi: 10.1186/s13195-017-0243-0.

25.

Wounded brain, ailing heart: Central autonomic network disruption in acute stroke.

Sörös P, Hachinski V.

Ann Neurol. 2017 Apr;81(4):495-497. doi: 10.1002/ana.24911. Epub 2017 Apr 3. No abstract available.

PMID:
28253547
26.

Henry J.M. Barnett, MD (1922-2016).

Hachinski V.

Neurology. 2017 Feb 28;88(9):824-825. doi: 10.1212/WNL.0000000000003668. No abstract available.

PMID:
28242847
27.
28.

Milder Alzheimer's disease pathology in heart failure and atrial fibrillation.

Sposato LA, Ruíz Vargas E, Riccio PM, Toledo JB, Trojanowski JQ, Kukull WA, Cipriano LE, Nucera A, Whitehead SN, Hachinski V.

Alzheimers Dement. 2017 Jul;13(7):770-777. doi: 10.1016/j.jalz.2016.12.002. Epub 2017 Feb 5.

29.

Atherosclerosis and vascular cognitive impairment neuropathological guideline.

Oveisgharan S, Hachinski V.

Brain. 2017 Feb;140(2):e12. doi: 10.1093/brain/aww304. Epub 2016 Dec 21. No abstract available.

PMID:
28007992
30.

Henry J.M. Barnett: 1922-2016.

Spence JD, Hachinski V.

Stroke. 2017 Jan;48(1):2-4. doi: 10.1161/STROKEAHA.116.015868. Epub 2016 Dec 8. No abstract available.

31.

Effect of Right Insular Involvement on Death and Functional Outcome After Acute Ischemic Stroke in the IST-3 Trial (Third International Stroke Trial).

Sposato LA, Cohen G, Wardlaw JM, Sandercock P, Lindley RI, Hachinski V; IST-3 Expert Reading Panel and the IST-3 Collaborative Group.

Stroke. 2016 Dec;47(12):2959-2965. Epub 2016 Nov 15.

32.

Right insular cortex involvement is consistently associated with death after ischaemic stroke.

Sposato LA, Hachinski V.

Eur J Neurol. 2017 Jan;24(1):1-2. doi: 10.1111/ene.13174. Epub 2016 Oct 31. No abstract available.

PMID:
27797138
33.

Revising the ICD: stroke is a brain disease.

Shakir R, Davis S, Norrving B, Grisold W, Carroll WM, Feigin V, Hachinski V.

Lancet. 2016 Nov 19;388(10059):2475-2476. doi: 10.1016/S0140-6736(16)31850-5. Epub 2016 Oct 14. No abstract available.

PMID:
27751564
34.

Preventing both stroke and dementia.

Hachinski V, Sposato LA, Kapral M.

Lancet Neurol. 2016 Jun;15(7):659. doi: 10.1016/S1474-4422(16)30041-2. Epub 2016 May 9. No abstract available.

PMID:
27302230
35.

Stroke is a burdensome but preventable brain disorder.

Hachinski V, Azarpazhooh MR.

Lancet Neurol. 2016 Aug;15(9):892-893. doi: 10.1016/S1474-4422(16)30120-X. Epub 2016 Jun 9. No abstract available.

PMID:
27291522
36.

Reproducibility and variability of quantitative magnetic resonance imaging markers in cerebral small vessel disease.

De Guio F, Jouvent E, Biessels GJ, Black SE, Brayne C, Chen C, Cordonnier C, De Leeuw FE, Dichgans M, Doubal F, Duering M, Dufouil C, Duzel E, Fazekas F, Hachinski V, Ikram MA, Linn J, Matthews PM, Mazoyer B, Mok V, Norrving B, O'Brien JT, Pantoni L, Ropele S, Sachdev P, Schmidt R, Seshadri S, Smith EE, Sposato LA, Stephan B, Swartz RH, Tzourio C, van Buchem M, van der Lugt A, van Oostenbrugge R, Vernooij MW, Viswanathan A, Werring D, Wollenweber F, Wardlaw JM, Chabriat H.

J Cereb Blood Flow Metab. 2016 Aug;36(8):1319-37. doi: 10.1177/0271678X16647396. Epub 2016 May 11. Review.

37.

A comparison between the MoCA and the MMSE visuoexecutive sub-tests in detecting abnormalities in TIA/stroke patients.

Mai LM, Sposato LA, Rothwell PM, Hachinski V, Pendlebury ST.

Int J Stroke. 2016 Jun;11(4):420-4. doi: 10.1177/1747493016632238. Epub 2016 Feb 10.

PMID:
26865154
38.

Correction. World Stroke Organization. Stroke and potentially preventable dementias proclamation: updated World Stroke Day proclamation.

Hachinski V.

Stroke. 2016 Feb;47(2):e37. doi: 10.1161/STR.0000000000000093. No abstract available.

39.

Group-based exercise combined with dual-task training improves gait but not vascular health in active older adults without dementia.

Gregory MA, Gill DP, Zou G, Liu-Ambrose T, Shigematsu R, Fitzgerald C, Hachinski V, Shoemaker K, Petrella RJ.

Arch Gerontol Geriatr. 2016 Mar-Apr;63:18-27. doi: 10.1016/j.archger.2015.11.008. Epub 2015 Dec 2.

PMID:
26791167
40.

Group-based exercise and cognitive-physical training in older adults with self-reported cognitive complaints: The Multiple-Modality, Mind-Motor (M4) study protocol.

Gregory MA, Gill DP, Shellington EM, Liu-Ambrose T, Shigematsu R, Zou G, Shoemaker K, Owen AM, Hachinski V, Stuckey M, Petrella RJ.

BMC Geriatr. 2016 Jan 16;16:17. doi: 10.1186/s12877-016-0190-9.

41.

Careers in neurology in a globalizing world.

Hachinski V.

Neurology. 2016 Jan 12;86(2):e21-3. doi: 10.1212/WNL.0000000000002267. No abstract available.

PMID:
26755622
42.
43.

Declining Incidence of Stroke and Dementia: Coincidence or Prevention Opportunity?

Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Cipriano LE, Hachinski V.

JAMA Neurol. 2015 Dec;72(12):1529-31. doi: 10.1001/jamaneurol.2015.2816. No abstract available.

PMID:
26658969
44.

Neurovascular Units: A New Cost Effective Model?

Nucera A, Cipriano L, Hachinski V.

Can J Neurol Sci. 2015 Sep;42(5):281-2. No abstract available.

PMID:
26594720
45.

Stroke and Potentially Preventable Dementias Proclamation: Updated World Stroke Day Proclamation.

Hachinski V; World Stroke Organization.

Stroke. 2015 Nov;46(11):3039-40. doi: 10.1161/STROKEAHA.115.011237. No abstract available. Erratum in: Stroke. 2016 Jan;47(1):e18. Stroke. 2016 Feb;47(2):e37.

46.

World stroke day proclamation: updated.

Hachinski V; World Stroke Organization.

Int J Stroke. 2015 Oct;10 Suppl A100:2-3. doi: 10.1111/ijs.12638. No abstract available.

PMID:
26502968
47.

The Healthy Mind, Healthy Mobility Trial: A Novel Exercise Program for Older Adults.

Gill DP, Gregory MA, Zou G, Liu-Ambrose T, Shigematsu R, Hachinski V, Fitzgerald C, Petrella RJ.

Med Sci Sports Exerc. 2016 Feb;48(2):297-306. doi: 10.1249/MSS.0000000000000758.

PMID:
26285025
48.

Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database.

Torralva T, Sposato LA, Riccio PM, Gleichgerrcht E, Roca M, Toledo JB, Trojanowski JQ, Kukull WA, Manes F, Hachinski V.

Neurobiol Aging. 2015 Oct;36(10):2861-8. doi: 10.1016/j.neurobiolaging.2015.06.026. Epub 2015 Jul 3.

49.

Consensus statement for diagnosis of subcortical small vessel disease.

Rosenberg GA, Wallin A, Wardlaw JM, Markus HS, Montaner J, Wolfson L, Iadecola C, Zlokovic BV, Joutel A, Dichgans M, Duering M, Schmidt R, Korczyn AD, Grinberg LT, Chui HC, Hachinski V.

J Cereb Blood Flow Metab. 2016 Jan;36(1):6-25. Review.

50.

Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and TIA: a systematic review and meta-analysis.

Sposato LA, Cipriano LE, Riccio PM, Hachinski V, Saposnik G.

Int J Stroke. 2015 Aug;10(6):801-7. doi: 10.1111/ijs.12555. Epub 2015 Jul 6. Review.

PMID:
26148134

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