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Nitric oxide-sensitive guanylyl cyclase stimulation improves experimental heart failure with preserved ejection fraction.

Wilck N, Markó L, Balogh A, Kräker K, Herse F, Bartolomaeus H, Szijártó IA, Gollasch M, Reichhart N, Strauss O, Heuser A, Brockschnieder D, Kretschmer A, Lesche R, Sohler F, Stasch JP, Sandner P, Luft FC, Müller DN, Dechend R, Haase N.

JCI Insight. 2018 Feb 22;3(4). pii: 96006. doi: 10.1172/jci.insight.96006. [Epub ahead of print]


Development and internal validation of the Simplified Mortality Score for the Intensive Care Unit (SMS-ICU).

Granholm A, Perner A, Krag M, Hjortrup PB, Haase N, Holst LB, Marker S, Collet MO, Jensen AKG, Møller MH.

Acta Anaesthesiol Scand. 2018 Mar;62(3):336-346. doi: 10.1111/aas.13048. Epub 2017 Dec 6.


Common Sense Approach to Managing Sepsis.

Perner A, Holst LB, Haase N, Hjortrup PB, Møller MH.

Crit Care Clin. 2018 Jan;34(1):127-138. doi: 10.1016/j.ccc.2017.08.009. Epub 2017 Oct 5. Review.


Pickering emulsifiers based on hydrophobically modified small granular starches - Part I: Manufacturing and physico-chemical characterization.

Marefati A, Wiege B, Haase NU, Matos M, Rayner M.

Carbohydr Polym. 2017 Nov 1;175:473-483. doi: 10.1016/j.carbpol.2017.07.044. Epub 2017 Jul 20.


Disturbed Placental Imprinting in Preeclampsia Leads to Altered Expression of DLX5, a Human-Specific Early Trophoblast Marker.

Zadora J, Singh M, Herse F, Przybyl L, Haase N, Golic M, Yung HW, Huppertz B, Cartwright JE, Whitley G, Johnsen GM, Levi G, Isbruch A, Schulz H, Luft FC, Müller DN, Staff AC, Hurst LD, Dechend R, Izsvák Z.

Circulation. 2017 Nov 7;136(19):1824-1839. doi: 10.1161/CIRCULATIONAHA.117.028110. Epub 2017 Sep 13.


Effects of hydroxyethyl starch 130/0.42 vs. Ringer's acetate on cytokine levels in severe sepsis.

Anthon CT, Müller RB, Haase N, Hjortrup PB, Møller K, Lange T, Wetterslev J, Perner A.

Acta Anaesthesiol Scand. 2017 Sep;61(8):904-913. doi: 10.1111/aas.12929. Epub 2017 Jun 26.


Protective Function of Ahnak1 in Vascular Healing after Wire Injury.

Haase N, Rüder C, Haase H, Kamann S, Kouno M, Morano I, Dechend R, Zohlnhöfer D, Haase T.

J Vasc Res. 2017;54(3):131-142. doi: 10.1159/000464287. Epub 2017 May 4.


Simplified Mortality Score for the Intensive Care Unit (SMS-ICU): protocol for the development and validation of a bedside clinical prediction rule.

Granholm A, Perner A, Krag M, Hjortrup PB, Haase N, Holst LB, Marker S, Collet MO, Jensen AK, Møller MH.

BMJ Open. 2017 Mar 9;7(3):e015339. doi: 10.1136/bmjopen-2016-015339.


Effects of fluid restriction on measures of circulatory efficacy in adults with septic shock.

Hjortrup PB, Haase N, Wetterslev J, Lange T, Bundgaard H, Rasmussen BS, Dey N, Wilkman E, Christensen L, Lodahl D, Bestle M, Perner A.

Acta Anaesthesiol Scand. 2017 Apr;61(4):390-398. doi: 10.1111/aas.12862. Epub 2017 Feb 1.


Restricting volumes of resuscitation fluid in adults with septic shock after initial management: the CLASSIC randomised, parallel-group, multicentre feasibility trial.

Hjortrup PB, Haase N, Bundgaard H, Thomsen SL, Winding R, Pettilä V, Aaen A, Lodahl D, Berthelsen RE, Christensen H, Madsen MB, Winkel P, Wetterslev J, Perner A; CLASSIC Trial Group; Scandinavian Critical Care Trials Group.

Intensive Care Med. 2016 Nov;42(11):1695-1705. Epub 2016 Sep 30.


The TetO rat as a new translational model for type 2 diabetic retinopathy by inducible insulin receptor knockdown.

Reichhart N, Crespo-Garcia S, Haase N, Golic M, Skosyrski S, Rübsam A, Herrspiegel C, Kociok N, Alenina N, Bader M, Dechend R, Strauss O, Joussen AM.

Diabetologia. 2017 Jan;60(1):202-211. Epub 2016 Oct 4.


A robust, high-throughput method for computing maize ear, cob, and kernel attributes automatically from images.

Miller ND, Haase NJ, Lee J, Kaeppler SM, de Leon N, Spalding EP.

Plant J. 2017 Jan;89(1):169-178. doi: 10.1111/tpj.13320. Epub 2016 Nov 19.


Natural Killer Cell Reduction and Uteroplacental Vasculopathy.

Golic M, Haase N, Herse F, Wehner A, Vercruysse L, Pijnenborg R, Balogh A, Saether PC, Dissen E, Luft FC, Przybyl L, Park JK, Alnaes-Katjavivi P, Staff AC, Verlohren S, Henrich W, Muller DN, Dechend R.

Hypertension. 2016 Oct;68(4):964-73. doi: 10.1161/HYPERTENSIONAHA.116.07800. Epub 2016 Aug 22.


Combining Passive Sampling with Toxicological Characterization of Complex Mixtures of Pollutants from the Aquatic Environment.

Jahnke A, Witt G, Schäfer S, Haase N, Escher BI.

Adv Biochem Eng Biotechnol. 2017;157:225-261. doi: 10.1007/10_2015_5014. Review.


Vitamin D depletion does not affect key aspects of the preeclamptic phenotype in a transgenic rodent model for preeclampsia.

Andersen LB, Golic M, Przybyl L, Sorensen GL, Jørgensen JS, Fruekilde P, von Versen-Höynck F, Herse F, Højskov CS, Dechend R, Christesen HT, Haase N.

J Am Soc Hypertens. 2016 Jul;10(7):597-607.e1. doi: 10.1016/j.jash.2016.05.008. Epub 2016 Jun 4.


High Levels of Methylarginines Were Associated With Increased Mortality in Patients With Severe Sepsis.

Mortensen KM, Itenov TS, Haase N, Müller RB, Ostrowski SR, Johansson PI, Olsen NV, Perner A, Søe-Jensen P, Bestle MH.

Shock. 2016 Oct;46(4):365-72. doi: 10.1097/SHK.0000000000000649.


CD74-Downregulation of Placental Macrophage-Trophoblastic Interactions in Preeclampsia.

Przybyl L, Haase N, Golic M, Rugor J, Solano ME, Arck PC, Gauster M, Huppertz B, Emontzpohl C, Stoppe C, Bernhagen J, Leng L, Bucala R, Schulz H, Heuser A, Weedon-Fekjær MS, Johnsen GM, Peetz D, Luft FC, Staff AC, Müller DN, Dechend R, Herse F.

Circ Res. 2016 Jun 24;119(1):55-68. doi: 10.1161/CIRCRESAHA.116.308304. Epub 2016 May 19.


Associations of Hospital and Patient Characteristics with Fluid Resuscitation Volumes in Patients with Severe Sepsis: Post Hoc Analyses of Data from a Multicentre Randomised Clinical Trial.

Hjortrup PB, Haase N, Wetterslev J, Perner A.

PLoS One. 2016 May 19;11(5):e0155767. doi: 10.1371/journal.pone.0155767. eCollection 2016.


Hypertensive retinopathy in a transgenic angiotensin-based model.

Reichhart N, Haase N, Crespo-Garcia S, Skosyrski S, Herrspiegel C, Kociok N, Fuchshofer R, Dillinger A, Poglitsch M, Müller DN, Joussen AM, Luft FC, Dechend R, Strauß O.

Clin Sci (Lond). 2016 Jul 1;130(13):1075-88. doi: 10.1042/CS20160092. Epub 2016 Mar 29.


Relaxin Treatment in an Ang-II-Based Transgenic Preeclamptic-Rat Model.

Haase N, Golic M, Herse F, Rugor J, Linz D, Solano ME, Müller DN, Dechend R.

PLoS One. 2016 Mar 10;11(3):e0150743. doi: 10.1371/journal.pone.0150743. eCollection 2016.


Gone fishing in a fluid trial.

Hjortrup PB, Haase N, Wetterslev J, Perner A.

Crit Care Resusc. 2016 Mar;18(1):55-8.


Metabolism of clofibric acid in zebrafish embryos (Danio rerio) as determined by liquid chromatography-high resolution-mass spectrometry.

Brox S, Seiwert B, Haase N, Küster E, Reemtsma T.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 Jul-Aug;185-186:20-28. doi: 10.1016/j.cbpc.2016.02.007. Epub 2016 Mar 3.


Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate.

Müller RB, Ostrowski SR, Haase N, Wetterslev J, Perner A, Johansson PI.

J Crit Care. 2016 Apr;32:16-20. doi: 10.1016/j.jcrc.2015.11.025. Epub 2015 Dec 8.


Strategies for Transferring Mixtures of Organic Contaminants from Aquatic Environments into Bioassays.

Jahnke A, Mayer P, Schäfer S, Witt G, Haase N, Escher BI.

Environ Sci Technol. 2016 Jun 7;50(11):5424-31. doi: 10.1021/acs.est.5b04687. Epub 2016 Feb 5.


Arterial waveform-analysis is of limited value in daily clinical practice in the intensive care unit.

Hennings LI, Haase N, Pedersen UG, Perner A.

Dan Med J. 2015 Sep;62(9). pii: A5136.


Improving Medical Decision Making and Health Promotion through Culture-Sensitive Health Communication: An Agenda for Science and Practice.

Betsch C, Böhm R, Airhihenbuwa CO, Butler R, Chapman GB, Haase N, Herrmann B, Igarashi T, Kitayama S, Korn L, Nurm ÜK, Rohrmann B, Rothman AJ, Shavitt S, Updegraff JA, Uskul AK.

Med Decis Making. 2016 Oct;36(7):811-33. doi: 10.1177/0272989X15600434. Epub 2015 Aug 21. Review.


An increased population of regulatory T cells improves the pathophysiology of placental ischemia in a rat model of preeclampsia.

Cornelius DC, Amaral LM, Harmon A, Wallace K, Thomas AJ, Campbell N, Scott J, Herse F, Haase N, Moseley J, Wallukat G, Dechend R, LaMarca B.

Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15;309(8):R884-91. doi: 10.1152/ajpregu.00154.2015. Epub 2015 Aug 19.


Udokumenterede behandlinger kan skade kritisk syge patienter.

Haase N, Perner A.

Ugeskr Laeger. 2015 Jul 20;177(30). pii: V67270. Danish. No abstract available.


Source Credibility and the Biasing Effect of Narrative Information on the Perception of Vaccination Risks.

Haase N, Betsch C, Renkewitz F.

J Health Commun. 2015 Aug;20(8):920-9. doi: 10.1080/10810730.2015.1018605. Epub 2015 Jun 11.


Shared Genomic Regions Between Derivatives of a Large Segregating Population of Maize Identified Using Bulked Segregant Analysis Sequencing and Traditional Linkage Analysis.

Haase NJ, Beissinger T, Hirsch CN, Vaillancourt B, Deshpande S, Barry K, Buell CR, Kaeppler SM, de Leon N.

G3 (Bethesda). 2015 Jun 1;5(8):1593-602. doi: 10.1534/g3.115.017665.


Effects of solvent concentration and composition on protein dynamics: 13C MAS NMR studies of elastin in glycerol-water mixtures.

Demuth D, Haase N, Malzacher D, Vogel M.

Biochim Biophys Acta. 2015 Aug;1854(8):995-1000. doi: 10.1016/j.bbapap.2015.04.012. Epub 2015 Apr 25.


Variability in targeted arterial oxygenation levels in patients with severe sepsis or septic shock.

Dahl RM, Grønlykke L, Haase N, Holst LB, Perner A, Wetterslev J, Rasmussen BS, Meyhoff CS; 6S-Trial and TRISS Trial investigators.

Acta Anaesthesiol Scand. 2015 Aug;59(7):859-69. doi: 10.1111/aas.12528. Epub 2015 Apr 24.


Association between biomarkers of endothelial injury and hypocoagulability in patients with severe sepsis: a prospective study.

Ostrowski SR, Haase N, Müller RB, Møller MH, Pott FC, Perner A, Johansson PI.

Crit Care. 2015 Apr 24;19:191. doi: 10.1186/s13054-015-0918-5.


Testing current practice is no mistake.

Perner A, Haase N, Wetterslev J, Holst LB.

Intensive Care Med. 2015 May;41(5):960. doi: 10.1007/s00134-015-3774-5. Epub 2015 Apr 8. No abstract available.


Regulatory T cells ameliorate intrauterine growth retardation in a transgenic rat model for preeclampsia.

Przybyl L, Ibrahim T, Haase N, Golic M, Rugor J, Luft FC, Bendix I, Serdar M, Wallukat G, Staff AC, Müller DN, Hünig T, Felderhoff-Müser U, Herse F, LaMarca B, Dechend R.

Hypertension. 2015 Jun;65(6):1298-306. doi: 10.1161/HYPERTENSIONAHA.114.04892. Epub 2015 Apr 6.


Colloid solutions in the perioperative setting.

Haase N, Perner A.

BMJ. 2015 Mar 27;350:h1656. doi: 10.1136/bmj.h1656. No abstract available.


A Grhl2-dependent gene network controls trophoblast branching morphogenesis.

Walentin K, Hinze C, Werth M, Haase N, Varma S, Morell R, Aue A, Pötschke E, Warburton D, Qiu A, Barasch J, Purfürst B, Dieterich C, Popova E, Bader M, Dechend R, Staff AC, Yurtdas ZY, Kilic E, Schmidt-Ott KM.

Development. 2015 Mar 15;142(6):1125-36. doi: 10.1242/dev.113829.


Vitamin D depletion aggravates hypertension and target-organ damage.

Andersen LB, Przybyl L, Haase N, von Versen-Höynck F, Qadri F, Jørgensen JS, Sorensen GL, Fruekilde P, Poglitsch M, Szijarto I, Gollasch M, Peters J, Muller DN, Christesen HT, Dechend R.

J Am Heart Assoc. 2015 Jan 28;4(2). pii: e001417. doi: 10.1161/JAHA.114.001417.


Acute kidney injury with hydroxyethyl starch 130/0.42 in severe sepsis.

Müller RB, Haase N, Lange T, Wetterslev J, Perner A.

Acta Anaesthesiol Scand. 2015 Mar;59(3):329-36. doi: 10.1111/aas.12453. Epub 2014 Dec 18.


Thromboelastography in patients with severe sepsis: a prospective cohort study.

Haase N, Ostrowski SR, Wetterslev J, Lange T, Møller MH, Tousi H, Steensen M, Pott F, Søe-Jensen P, Nielsen J, Hjortrup PB, Johansson PI, Perner A.

Intensive Care Med. 2015 Jan;41(1):77-85. doi: 10.1007/s00134-014-3552-9. Epub 2014 Nov 21.


Predictive value of NGAL for use of renal replacement therapy in patients with severe sepsis.

Hjortrup PB, Haase N, Treschow F, Møller MH, Perner A.

Acta Anaesthesiol Scand. 2015 Jan;59(1):25-34. doi: 10.1111/aas.12427. Epub 2014 Nov 2.


Lower versus higher hemoglobin threshold for transfusion in septic shock.

Holst LB, Haase N, Wetterslev J, Wernerman J, Guttormsen AB, Karlsson S, Johansson PI, Aneman A, Vang ML, Winding R, Nebrich L, Nibro HL, Rasmussen BS, Lauridsen JR, Nielsen JS, Oldner A, Pettilä V, Cronhjort MB, Andersen LH, Pedersen UG, Reiter N, Wiis J, White JO, Russell L, Thornberg KJ, Hjortrup PB, Müller RG, Møller MH, Steensen M, Tjäder I, Kilsand K, Odeberg-Wernerman S, Sjøbø B, Bundgaard H, Thyø MA, Lodahl D, Mærkedahl R, Albeck C, Illum D, Kruse M, Winkel P, Perner A; TRISS Trial Group; Scandinavian Critical Care Trials Group.

N Engl J Med. 2014 Oct 9;371(15):1381-91. doi: 10.1056/NEJMoa1406617. Epub 2014 Oct 1.


Bcl10 mediates angiotensin II-induced cardiac damage and electrical remodeling.

Markó L, Henke N, Park JK, Spallek B, Qadri F, Balogh A, Apel IJ, Oravecz-Wilson KI, Choi M, Przybyl L, Binger KJ, Haase N, Wilck N, Heuser A, Fokuhl V, Ruland J, Lucas PC, McAllister-Lucas LM, Luft FC, Dechend R, Müller DN.

Hypertension. 2014 Nov;64(5):1032-9. doi: 10.1161/HYPERTENSIONAHA.114.03900. Epub 2014 Sep 2.


Individual patient data meta-analysis of hydroxyethyl starch 130/0.4-0.42 versus crystalloid for fluid resuscitation in patients with severe sepsis: a statistical analysis plan.

Hammond NE, Haase N, Billot L, Wetterslev J, Saxena MK, Finfer S, Perner A, Myburgh J.

Crit Care Resusc. 2014 Jun;16(2):96-103.


Long-term outcomes in patients with severe sepsis randomised to resuscitation with hydroxyethyl starch 130/0.42 or Ringer's acetate.

Perner A, Haase N, Winkel P, Guttormsen AB, Tenhunen J, Klemenzson G, Müller RG, Aneman A, Wetterslev J.

Intensive Care Med. 2014 Jul;40(7):927-34. doi: 10.1007/s00134-014-3311-y. Epub 2014 May 8.


Relaxin does not improve Angiotensin II-induced target-organ damage.

Haase N, Rugor J, Przybyl L, Qadri F, Müller DN, Dechend R.

PLoS One. 2014 Apr 7;9(4):e93743. doi: 10.1371/journal.pone.0093743. eCollection 2014.


Mortality in patients with hypovolemic shock treated with colloids or crystalloids.

Perner A, Haase N, Wetterslev J.

JAMA. 2014 Mar 12;311(10):1067. doi: 10.1001/jama.2014.830. No abstract available.


Association between sympathoadrenal activation, fibrinolysis, and endothelial damage in septic patients: a prospective study.

Johansson PI, Haase N, Perner A, Ostrowski SR.

J Crit Care. 2014 Jun;29(3):327-33. doi: 10.1016/j.jcrc.2013.10.028. Epub 2014 Jan 28.


Red blood cell transfusion in septic shock - clinical characteristics and outcome of unselected patients in a prospective, multicentre cohort.

Rosland RG, Hagen MU, Haase N, Holst LB, Plambech M, Madsen KR, Søe-Jensen P, Poulsen LM, Bestle M, Perner A.

Scand J Trauma Resusc Emerg Med. 2014 Feb 27;22:14. doi: 10.1186/1757-7241-22-14.

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