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Items: 23

1.

Integration of Distinct ShcA Signaling Complexes Promotes Breast Tumor Growth and Tyrosine Kinase Inhibitor Resistance.

Ha JR, Ahn R, Smith HW, Sabourin V, Hébert S, Cepeda Cañedo E, Im YK, Kleinman CL, Muller WJ, Ursini-Siegel J.

Mol Cancer Res. 2018 Feb 16. doi: 10.1158/1541-7786.MCR-17-0623. [Epub ahead of print]

PMID:
29453318
2.

Bacterial production and structure-functional validation of a recombinant antigen-binding fragment (Fab) of an anti-cancer therapeutic antibody targeting epidermal growth factor receptor.

Kim JH, Sim DW, Park D, Jung TG, Lee S, Oh T, Ha JR, Seok SH, Seo MD, Kang HC, Kim YP, Won HS.

Appl Microbiol Biotechnol. 2016 Dec;100(24):10521-10529. Epub 2016 Jul 28.

PMID:
27470143
3.

The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic Responsiveness.

Ha JR, Siegel PM, Ursini-Siegel J.

J Cell Biochem. 2016 Sep;117(9):1971-90. doi: 10.1002/jcb.25561. Epub 2016 Apr 14. Review.

PMID:
27392311
4.

A New Fiber Preform with Nanocarbon Binder for Manufacturing Carbon Fiber Reinforced Composite by Liquid Molding Process.

Seong DG, Ha JR, Lee JU, Lee W, Kim BS.

J Nanosci Nanotechnol. 2015 Nov;15(11):9057-60.

PMID:
26726642
5.

p66ShcA promotes breast cancer plasticity by inducing an epithelial-to-mesenchymal transition.

Hudson J, Ha JR, Sabourin V, Ahn R, La Selva R, Livingstone J, Podmore L, Knight J, Forrest L, Beauchemin N, Hallett M, Park M, Ursini-Siegel J.

Mol Cell Biol. 2014 Oct 1;34(19):3689-701. doi: 10.1128/MCB.00341-14. Epub 2014 Jul 28.

6.

The ShcA adaptor activates AKT signaling to potentiate breast tumor angiogenesis by stimulating VEGF mRNA translation in a 4E-BP-dependent manner.

Im YK, La Selva R, Gandin V, Ha JR, Sabourin V, Sonenberg N, Pawson T, Topisirovic I, Ursini-Siegel J.

Oncogene. 2015 Mar 26;34(13):1729-35. doi: 10.1038/onc.2014.110. Epub 2014 May 19.

PMID:
24837366
7.

YY162 prevents ADHD-like behavioral side effects and cytotoxicity induced by Aroclor1254 via interactive signaling between antioxidant potential, BDNF/TrkB, DAT and NET.

Nam Y, Shin EJ, Shin SW, Lim YK, Jung JH, Lee JH, Ha JR, Chae JS, Ko SK, Jeong JH, Jang CG, Kim HC.

Food Chem Toxicol. 2014 Mar;65:280-92. doi: 10.1016/j.fct.2013.12.046. Epub 2014 Jan 3.

PMID:
24394491
8.

β-catenin is O-GlcNAc glycosylated at Serine 23: implications for β-catenin's subcellular localization and transactivator function.

Ha JR, Hao L, Venkateswaran G, Huang YH, Garcia E, Persad S.

Exp Cell Res. 2014 Feb 15;321(2):153-66. doi: 10.1016/j.yexcr.2013.11.021. Epub 2013 Dec 14.

PMID:
24342833
9.

The ShcA PTB domain functions as a biological sensor of phosphotyrosine signaling during breast cancer progression.

Ahn R, Sabourin V, Ha JR, Cory S, Maric G, Im YK, Hardy WR, Zhao H, Park M, Hallett M, Siegel PM, Pawson T, Ursini-Siegel J.

Cancer Res. 2013 Jul 15;73(14):4521-32. doi: 10.1158/0008-5472.CAN-12-4178. Epub 2013 May 21.

10.

Peptidomimetic small-molecule compounds promoting cardiogenesis of stem cells.

Oh SW, Lee JB, Kim B, Jeon S, Kim MK, Nam KH, Ha JR, Bhatia M, Oh GT, Kim DY.

Arch Pharm Res. 2012 Nov;35(11):1979-88. doi: 10.1007/s12272-012-1115-6. Epub 2012 Dec 4.

PMID:
23212640
11.

Cadherin switch from E- to N-cadherin in melanoma progression is regulated by the PI3K/PTEN pathway through Twist and Snail.

Hao L, Ha JR, Kuzel P, Garcia E, Persad S.

Br J Dermatol. 2012 Jun;166(6):1184-97. doi: 10.1111/j.1365-2133.2012.10824.x. Epub 2012 May 8.

PMID:
22332917
12.

Angiogenic remodeling in pediatric EoE is associated with increased levels of VEGF-A, angiogenin, IL-8, and activation of the TNF-α-NFκB pathway.

Persad R, Huynh HQ, Hao L, Ha JR, Sergi C, Srivastava R, Persad S.

J Pediatr Gastroenterol Nutr. 2012 Sep;55(3):251-60. doi: 10.1097/MPG.0b013e31824b6391.

PMID:
22331014
13.

Design, synthesis, and evaluation of 2-aryl-7-(3',4'-dialkoxyphenyl)-pyrazolo[1,5-a]pyrimidines as novel PDE-4 inhibitors.

Kim I, Song JH, Park CM, Jeong JW, Kim HR, Ha JR, No Z, Hyun YL, Cho YS, Sook Kang N, Jeon DJ.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):922-6. doi: 10.1016/j.bmcl.2009.12.070. Epub 2009 Dec 23.

PMID:
20053559
14.
15.

Comparison of in vivo nephrotoxicity in the rabbit by a pyrrolidinyl-thio Carbapenem CW-270031.

Kim JM, Ha JR, Oh SW, Kim HG, Lee JM, Kim BO, Lee DG, Lee SH, Kim JG.

J Microbiol Biotechnol. 2008 Nov;18(11):1768-72.

16.

Potential inhibition of PDK1/Akt signaling by phenothiazines suppresses cancer cell proliferation and survival.

Choi JH, Yang YR, Lee SK, Kim SH, Kim YH, Cha JY, Oh SW, Ha JR, Ryu SH, Suh PG.

Ann N Y Acad Sci. 2008 Sep;1138:393-403. doi: 10.1196/annals.1414.041.

PMID:
18837915
17.

CW-270033, a novel pyrrolidinyl-thio carbapenem, has potent antimicrobial activity in vitro and in vivo.

Kim J, Ha JR, Oh SW, Kim HG, Lee JM, Lee DG, Lee SH, Kim JG.

Biol Pharm Bull. 2007 Mar;30(3):575-9.

18.

A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected].

Emami KH, Nguyen C, Ma H, Kim DH, Jeong KW, Eguchi M, Moon RT, Teo JL, Kim HY, Moon SH, Ha JR, Kahn M.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12682-7. Epub 2004 Aug 16. Erratum in: Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16707.

20.

In vivo antitumor efficacy of CW252053, a folate-based thymidylate synthase inhibitor.

Oh SW, Ha JR, Baek DJ.

Arch Pharm Res. 2001 Aug;24(4):323-6.

PMID:
11534765
22.
23.

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