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Items: 1 to 50 of 221

1.

The Prognostic Relevance of Sentinel Lymph Node Metastases Assessed by PHGR1 mRNA Quantification in Stage I to III Colon Cancer.

Oltedal S, Kørner H, Aasprong OG, Hussain I, Tjensvoll K, Smaaland R, Søreide JA, Søreide K, Lothe RA, Heikkilä R, Gilje B, Nordgård O.

Transl Oncol. 2018 Feb 20;11(2):436-443. doi: 10.1016/j.tranon.2018.01.015. [Epub ahead of print]

PMID:
29475140
2.

Expression profiling and intracellular localization studies of the novel Proline-, Histidine-, and Glycine-rich protein 1 suggest an essential role in gastro-intestinal epithelium and a potential clinical application in colorectal cancer diagnostics.

Oltedal S, Skaland I, Maple-Grødem J, Tjensvoll K, Janssen EAM, Gilje B, Smaaland R, Heikkilä R, Nordgård O.

BMC Gastroenterol. 2018 Feb 7;18(1):26. doi: 10.1186/s12876-018-0752-8.

3.

Single dose of mirtazapine modulates whole-brain functional connectivity during emotional narrative processing.

Komulainen E, Glerean E, Meskanen K, Heikkilä R, Nummenmaa L, Raij TT, Lahti J, Jylhä P, Melartin T, Isometsä E, Ekelund J.

Psychiatry Res. 2017 May 30;263:61-69. doi: 10.1016/j.pscychresns.2017.03.009. Epub 2017 Mar 22.

PMID:
28366871
4.

Chemotherapy in end-of-life care.

Heikkilä R, Kaasa S.

Ann Oncol. 2017 Apr 1;28(4):684-685. doi: 10.1093/annonc/mdx039. No abstract available.

PMID:
28327919
5.

A single dose of mirtazapine attenuates neural responses to self-referential processing.

Komulainen E, Heikkilä R, Meskanen K, Raij TT, Nummenmaa L, Lahti J, Jylhä P, Melartin T, Harmer CJ, Isometsä E, Ekelund J.

J Psychopharmacol. 2016 Jan;30(1):23-32. doi: 10.1177/0269881115616384. Epub 2015 Nov 17.

PMID:
26577062
6.

Double-Deficit Hypothesis in a Clinical Sample: Extension Beyond Reading.

Heikkilä R, Torppa M, Aro M, Närhi V, Ahonen T.

J Learn Disabil. 2016 Sep;49(5):546-60. doi: 10.1177/0022219415572895. Epub 2015 Feb 25.

PMID:
25716215
7.

Psychosocial Functioning of Children with and without Dyslexia: A Follow-up Study from Ages Four to Nine.

Parhiala P, Torppa M, Eklund K, Aro T, Poikkeus AM, Heikkilä R, Ahonen T.

Dyslexia. 2015 Aug;21(3):197-211. doi: 10.1002/dys.1486. Epub 2014 Nov 27.

PMID:
25428888
8.

Prognostic relevance of occult metastases detected by cytokeratin 20 and mucin 2 mRNA levels in sentinel lymph nodes from colon cancer patients.

Nordgård O, Oltedal S, Aasprong OG, Søreide JA, Søreide K, Tjensvoll K, Gilje B, Heikkilä R, Guriby M, Lothe RA, Smaaland R, Kørner H.

Ann Surg Oncol. 2012 Nov;19(12):3719-26. doi: 10.1245/s10434-012-2454-8. Epub 2012 Jul 3.

PMID:
22752373
9.

Persistent tumor cells in bone marrow of non-metastatic breast cancer patients after primary surgery are associated with inferior outcome.

Tjensvoll K, Oltedal S, Heikkilä R, Kvaløy JT, Gilje B, Reuben JM, Smaaland R, Nordgård O.

BMC Cancer. 2012 May 28;12:190. doi: 10.1186/1471-2407-12-190.

10.

Bacterial skin flora and contamination of blood components: do we defer blood donors wisely?

Pastila S, Lönnroth M, Heikkilä R, Heikkilä H, Carlson P.

Vox Sang. 2012 Aug;103(2):93-8. doi: 10.1111/j.1423-0410.2012.01591.x. Epub 2012 Feb 20.

PMID:
22348231
11.
12.

Heterogeneous distribution of K-ras mutations in primary colon carcinomas: implications for EGFR-directed therapy.

Oltedal S, Aasprong OG, Møller JH, Kørner H, Gilje B, Tjensvoll K, Birkemeyer EM, Heikkilä R, Smaaland R, Nordgård O.

Int J Colorectal Dis. 2011 Oct;26(10):1271-7. doi: 10.1007/s00384-011-1233-5. Epub 2011 May 15.

PMID:
21573767
13.

Sound energy and the magnitude of change: effects on mismatch negativity.

Takegata R, Heikkilä R, Näätänen R.

Neuroreport. 2011 Mar 9;22(4):171-4. doi: 10.1097/WNR.0b013e328343c3b5.

PMID:
21278614
14.

Do people regard cheaper medicines effective? Population survey on public opinion of generic substitution in Finland.

Heikkilä R, Mäntyselkä P, Ahonen R.

Pharmacoepidemiol Drug Saf. 2011 Feb;20(2):185-91. doi: 10.1002/pds.2084. Epub 2010 Dec 23.

PMID:
21254290
15.

Disseminated tumor cells in bone marrow assessed by TWIST1, cytokeratin 19, and mammaglobin A mRNA predict clinical outcome in operable breast cancer patients.

Tjensvoll K, Oltedal S, Farmen RK, Shammas FV, Heikkilä R, Kvaløy JT, Gilje B, Smaaland R, Nordgård O.

Clin Breast Cancer. 2010 Oct 1;10(5):378-84. doi: 10.3816/CBC.2010.n.050.

PMID:
20920982
16.

Biological therapy for psoriatic arthritis in clinical practice: outcomes up to 2 years.

Virkki LM, Sumathikutty BC, Aarnio M, Valleala H, Heikkilä R, Kauppi M, Karstila K, Pirilä L, Ekman P, Salomaa S, Romu M, Seppälä J, Niinisalo H, Konttinen YT, Nordström DC.

J Rheumatol. 2010 Nov;37(11):2362-8. doi: 10.3899/jrheum.091477. Epub 2010 Aug 17.

PMID:
20716655
17.

Detection of occult metastases in sentinel lymph nodes from colon cancer patients by K-ras mutation peptide nucleic acid clamp PCR.

Oltedal S, Gilje B, Kørner H, Aasprong OG, Tjensvoll K, Heikkilä R, Smaaland R, Nordgård O.

Ann Surg. 2010 Jun;251(6):1087-91. doi: 10.1097/SLA.0b013e3181dae1bc.

PMID:
20485143
18.

[Recurrence and survival after breast-conserving treatment of breast cancer].

Mjaaland I, Segers RM, Dybvik KI, Bjerkeset O, Kvaløy JT, Heikkilä R.

Tidsskr Nor Laegeforen. 2010 Feb 25;130(4):370-4. doi: 10.4045/tidsskr.09.0484. Norwegian.

19.

Nurse informaticians in Finland - who are they and what are they doing?

Saranto K, Junttila K, Ahonen O, Ensio A, Heikkilä R, Lehtomäki S, Liljamo P.

Stud Health Technol Inform. 2009;146:868.

PMID:
19593026
20.

Neural process underlying gap detection for spectrally rich and asymmetrical markers.

Takegata R, Heikkilä R, Näätänen R.

Neuroreport. 2009 Aug 5;20(12):1120-4. doi: 10.1097/WNR.0b013e32832eb80e.

PMID:
19590396
21.

Quantitative RT-PCR detection of tumor cells in sentinel lymph nodes isolated from colon cancer patients with an ex vivo approach.

Nordgård O, Oltedal S, Kørner H, Aasprong OG, Tjensvoll K, Gilje B, Heikkilä R.

Ann Surg. 2009 Apr;249(4):602-7. doi: 10.1097/SLA.0b013e31819ec923.

PMID:
19300229
22.

The potential of cytokeratin 20 and mucin 2 mRNA as metastasis markers in regional lymph nodes of colon cancer patients investigated by quantitative RT-PCR.

Nordgård O, Oltedal S, Kørner H, Aasprong OG, Tjensvoll K, Gilje B, Heikkilä R.

Int J Colorectal Dis. 2009 Mar;24(3):261-8. doi: 10.1007/s00384-008-0613-y. Epub 2009 Jan 3.

PMID:
19119477
23.

Rapid automatized naming and learning disabilities: does RAN have a specific connection to reading or not?

Heikkilä R, Närhi V, Aro M, Ahonen T.

Child Neuropsychol. 2009 Jul;15(4):343-58. doi: 10.1080/09297040802537653.

PMID:
19105054
24.

A small subgroup of operable breast cancer patients with poor prognosis identified by quantitative real-time RT-PCR detection of mammaglobin A and trefoil factor 1 mRNA expression in bone marrow.

Tjensvoll K, Gilje B, Oltedal S, Shammas VF, Kvaløy JT, Heikkilä R, Nordgård O.

Breast Cancer Res Treat. 2009 Jul;116(2):329-38. doi: 10.1007/s10549-008-0204-1. Epub 2008 Oct 10.

PMID:
18846421
25.

High-fidelity DNA polymerase enhances the sensitivity of a peptide nucleic acid clamp PCR assay for K-ras mutations.

Gilje B, Heikkilä R, Oltedal S, Tjensvoll K, Nordgård O.

J Mol Diagn. 2008 Jul;10(4):325-31. doi: 10.2353/jmoldx.2008.070183. Epub 2008 Jun 13.

26.

A randomized phase III multicenter trial comparing irinotecan in combination with the Nordic bolus 5-FU and folinic acid schedule or the bolus/infused de Gramont schedule (Lv5FU2) in patients with metastatic colorectal cancer.

Glimelius B, Sørbye H, Balteskard L, Byström P, Pfeiffer P, Tveit K, Heikkilä R, Keldsen N, Albertsson M, Starkhammar H, Garmo H, Berglund A.

Ann Oncol. 2008 May;19(5):909-14. doi: 10.1093/annonc/mdm588. Epub 2008 Jan 21.

PMID:
18209013
27.

[Sentinel lymph nodes in colorectal cancer].

Nordgård O, Kørner H, Aasprong OG, Heikkilä R.

Tidsskr Nor Laegeforen. 2007 Nov 1;127(21):2829-33. Review. Norwegian.

28.

Bone marrow cytokeratin 19 mRNA level is an independent predictor of relapse-free survival in operable breast cancer patients.

Farmen RK, Nordgård O, Gilje B, Shammas FV, Kvaløy JT, Oltedal S, Heikkilä R.

Breast Cancer Res Treat. 2008 Mar;108(2):251-8. Epub 2007 May 10.

PMID:
17492378
29.

Customers' and physicians' opinions of and experiences with generic substitution during the first year in Finland.

Heikkilä R, Mäntyselkä P, Hartikainen-Herranen K, Ahonen R.

Health Policy. 2007 Aug;82(3):366-74. Epub 2006 Dec 1.

PMID:
17141355
30.

Error propagation in relative real-time reverse transcription polymerase chain reaction quantification models: the balance between accuracy and precision.

Nordgård O, Kvaløy JT, Farmen RK, Heikkilä R.

Anal Biochem. 2006 Sep 15;356(2):182-93. Epub 2006 Jul 14.

PMID:
16899212
31.

TOP2A and HER2 gene amplification as predictors of response to anthracycline treatment in breast cancer.

Villman K, Sjöström J, Heikkilä R, Hultborn R, Malmström P, Bengtsson NO, Söderberg M, Saksela E, Blomqvist C.

Acta Oncol. 2006;45(5):590-6.

PMID:
16864174
32.

Cereulide-producing strains of Bacillus cereus show diversity.

Apetroaie C, Andersson MA, Spröer C, Tsitko I, Shaheen R, Jääskeläinen EL, Wijnands LM, Heikkilä R, Salkinoja-Salonen MS.

Arch Microbiol. 2005 Nov;184(3):141-51. Epub 2005 Nov 10.

PMID:
16195898
33.

[Preventive vaccines against papillomavirus and cervix cancer will soon enter clinical practice].

Lehtinen M, Malm C, Apter D, Heikkilä R, Heino P, Rimpilä K, Zilliacus R, Paavonen J.

Lakartidningen. 2003 Oct 23;100(43):3408-12. Review. Swedish.

PMID:
14626768
34.

[Radiotherapy after breast-conserving surgery in the treatment of breast cancer: early results from a non-university hospital in Norway].

Mjaaland I, Dybvik KI, Heikkilä R, Nysted A.

Tidsskr Nor Laegeforen. 2003 Jun 12;123(12):1683-4. Norwegian.

PMID:
12821990
35.

Brachytherapy for prostate cancer: a systematic review of clinical and cost effectiveness.

Norderhaug I, Dahl O, Høisaeter PA, Heikkilä R, Klepp O, Olsen DR, Kristiansen IS, Waehre H, Bjerklund Johansen TE.

Eur Urol. 2003 Jul;44(1):40-6. Review.

PMID:
12814673
36.

Detection of lymph node micrometastases in colorectal cancer.

Nordgård O, Aloysius TA, Todnem K, Heikkilä R, Ogreid D.

Scand J Gastroenterol. 2003 Feb;38(2):125-32. Review. No abstract available.

PMID:
12678327
37.

[Brachytherapy in prostatic cancer].

Norderhaug I, Johansen TB, Dahl O, Høisaeter PA, Heikkilä R, Klepp O, Olsen DR, Kristiansen IS, Waehre H.

Tidsskr Nor Laegeforen. 2002 Nov 30;122(29):2795-8. Review. Norwegian.

PMID:
12523149
38.

[A vaccine against papillomavirus infections and cancer].

Lehtinen M, Apter D, Heikkilä R, Heino P, Idänpään-Heikkilä I, Rimpilä K, Malm C, Zilliacus R.

Duodecim. 2002;118(13):1397-404. Review. Finnish. No abstract available.

PMID:
12239887
39.

Tumour microvessel density as predictor of chemotherapy response in breast cancer patients.

Tynninen O, Sjöström J, von Boguslawski K, Bengtsson NO, Heikkilä R, Malmström P, Ostenstad B, Wist E, Valvere V, Saksela E, Paavonen T, Blomqvist C.

Br J Cancer. 2002 Jun 17;86(12):1905-8.

40.

[Sinus thrombosis in a young woman using oral contraceptives].

Heikkilä R, Hakamies L.

Duodecim. 1998;114(7):643-4. Finnish. No abstract available.

PMID:
11524747
41.

Serial quantitative PCR analysis of bone marrow samples from breast cancer patients to monitor systemic micrometastases.

Shammas FV, Deak E, Nysted A, van Eekelen JA, Osland A, Heikkilä R.

Anticancer Res. 2001 May-Jun;21(3C):2099-106.

PMID:
11501832
42.

Effects of polymer dilution on quantitative polymerase chain reaction performed by capillary electrophoresis.

Shammas FV, Wee L, van Eekelen JA, Heikkilä R, Osland A.

Anal Biochem. 2001 Jun 15;293(2):293-5. No abstract available.

PMID:
11399047
43.

Improvement of quantitative PCR reproducibility by betaine as determined by fluorescence-based method.

Shammas FV, Heikkilä R, Osland A.

Biotechniques. 2001 May;30(5):950-2, 954. No abstract available.

PMID:
11355355
44.

Fluorescence-based method for measuring and determining the mechanisms of recombination in quantitative PCR.

Shammas FV, Heikkilä R, Osland A.

Clin Chim Acta. 2001 Feb;304(1-2):19-28.

PMID:
11165195
45.

Quantitative analysis of cytokeratin 20 gene expression using RT-PCR and capillary electrophoresis with fluorescent DNA detection.

van Eekelen JA, Shammas FV, Wee L, Heikkilä R, Osland A.

Clin Biochem. 2000 Aug;33(6):457-64.

PMID:
11074237
46.

Sensitive and quantitative one-step polymerase chain reaction using capillary electrophoresis and fluorescence detection for measuring cytokeratin 19 expression.

Shammas FV, Van Eekelen JA, Wee L, Heikkilä R, Osland A.

Scand J Clin Lab Invest. 1999 Dec;59(8):635-42.

PMID:
10691055
47.

Serum testosterone and sex hormone-binding globulin concentrations and the risk of prostate carcinoma: a longitudinal study.

Heikkilä R, Aho K, Heliövaara M, Hakama M, Marniemi J, Reunanen A, Knekt P.

Cancer. 1999 Jul 15;86(2):312-5.

PMID:
10421267
48.

Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer.

Cunningham D, Pyrhönen S, James RD, Punt CJ, Hickish TF, Heikkila R, Johannesen TB, Starkhammar H, Topham CA, Awad L, Jacques C, Herait P.

Lancet. 1998 Oct 31;352(9138):1413-8.

PMID:
9807987
49.

Serum androgen-anabolic hormones and the risk of rheumatoid arthritis.

Heikkilä R, Aho K, Heliövaara M, Knekt P, Reunanen A, Aromaa A, Leino A, Palosuo T.

Ann Rheum Dis. 1998 May;57(5):281-5.

50.

Purification of filaggrin from human epidermis and measurement of antifilaggrin autoantibodies in sera from patients with rheumatoid arthritis by an enzyme-linked immunosorbent assay.

Palosuo T, Lukka M, Alenius H, Kalkkinen N, Aho K, Kurki P, Heikkilä R, Nykänen M, von Essen R.

Int Arch Allergy Immunol. 1998 Apr;115(4):294-302.

PMID:
9566352

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