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Items: 1 to 50 of 127

1.

[Big data-also relevant in rheumatology?]

Burmester GR, Häupl T.

Z Rheumatol. 2018 Apr;77(3):192-194. doi: 10.1007/s00393-018-0437-2. German. No abstract available.

PMID:
29619762
2.

Gene expression profiling of human bronchial epithelial cells exposed to fine particulate matter (PM2.5) from biomass combustion.

Popadić D, Heßelbach K, Richter-Brockmann S, Kim GJ, Flemming S, Schmidt-Heck W, Häupl T, Bonin M, Dornhof R, Achten C, Günther S, Humar M, Merfort I.

Toxicol Appl Pharmacol. 2018 Mar 26;347:10-22. doi: 10.1016/j.taap.2018.03.024. [Epub ahead of print] No abstract available.

PMID:
29596927
3.

Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity.

Schwedler C, Häupl T, Kalus U, Blanchard V, Burmester GR, Poddubnyy D, Hoppe B.

Arthritis Res Ther. 2018 Mar 14;20(1):44. doi: 10.1186/s13075-018-1540-0.

4.

[Relevance of big data for molecular diagnostics].

Bonin-Andresen M, Smiljanovic B, Stuhlmüller B, Sörensen T, Grützkau A, Häupl T.

Z Rheumatol. 2018 Apr;77(3):195-202. doi: 10.1007/s00393-018-0436-3. Review. German.

PMID:
29520680
5.

Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.

Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T.

Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30.

6.

Disease relevant modifications of the methylome and transcriptome by particulate matter (PM2.5) from biomass combustion.

Heßelbach K, Kim GJ, Flemming S, Häupl T, Bonin M, Dornhof R, Günther S, Merfort I, Humar M.

Epigenetics. 2017 Sep;12(9):779-792. doi: 10.1080/15592294.2017.1356555. Epub 2017 Oct 27.

7.

15 years of the histopathological synovitis score, further development and review: A diagnostic score for rheumatology and orthopaedics.

Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Casadonte R, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Sunitsch S, Tikhilov R, Morawietz L.

Pathol Res Pract. 2017 Aug;213(8):874-881. doi: 10.1016/j.prp.2017.05.005. Epub 2017 May 19. Review.

PMID:
28687159
8.

Characterization of single cell derived cultures of periosteal progenitor cells to ensure the cell quality for clinical application.

Stich S, Loch A, Park SJ, Häupl T, Ringe J, Sittinger M.

PLoS One. 2017 May 31;12(5):e0178560. doi: 10.1371/journal.pone.0178560. eCollection 2017.

9.

[Fifteen years of the histopathological synovitis score : Review and further developments of a diagnostic score].

Krenn V, Perino G, Rüther W, Krenn VT, Huber M, Hügle T, Najm A, Müller S, Boettner F, Pessler F, Waldstein W, Kriegsmann J, Häupl T, Wienert S, Krukemeyer MG, Sesselmann S, Tikhilov R, Morawietz L.

Z Rheumatol. 2017 Aug;76(6):539-546. doi: 10.1007/s00393-017-0308-2. Review. German.

PMID:
28470440
10.

Type I interferon as a biomarker in autoimmunity and viral infection: a leukocyte subset-specific analysis unveils hidden diagnostic options.

Strauß R, Rose T, Flint SM, Klotsche J, Häupl T, Peck-Radosavljevic M, Yoshida T, Kyogoku C, Flechsig A, Becker AM, Dao KH, Radbruch A, Burmester GR, Lyons PA, Davis LS, Hiepe F, Grützkau A, Biesen R.

J Mol Med (Berl). 2017 Jul;95(7):753-765. doi: 10.1007/s00109-017-1515-7. Epub 2017 Mar 29.

PMID:
28357476
11.

miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics.

Duroux-Richard I, Roubert C, Ammari M, Présumey J, Grün JR, Häupl T, Grützkau A, Lecellier CH, Boitez V, Codogno P, Escoubet J, Pers YM, Jorgensen C, Apparailly F.

Blood. 2016 Dec 29;128(26):3125-3136. doi: 10.1182/blood-2016-02-697003. Epub 2016 Oct 4.

12.

Differential Expression of miR-4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF).

Latsoudis H, Mashreghi MF, Grün JR, Chang HD, Stuhlmüller B, Repa A, Gergiannaki I, Kabouraki E, Vlachos GS, Häupl T, Radbruch A, Sidiropoulos P, Doukoumetzidis K, Kardassis D, Niewold TB, Boumpas DT, Goulielmos GN.

J Cell Physiol. 2017 Jun;232(6):1326-1336. doi: 10.1002/jcp.25602. Epub 2016 Dec 20.

PMID:
27636101
13.

Genomic stratification by expression of HLA-DRB4 alleles identifies differential innate and adaptive immune transcriptional patterns - A strategy to detect predictors of methotrexate response in early rheumatoid arthritis.

Stuhlmüller B, Mans K, Tandon N, Bonin MO, Smiljanovic B, Sörensen TA, Schendel P, Martus P, Listing J, Detert J, Backhaus M, Neumann T, Winchester RJ, Burmester GR, Häupl T.

Clin Immunol. 2016 Oct;171:50-61. doi: 10.1016/j.clim.2016.08.013. Epub 2016 Aug 26.

PMID:
27570220
14.

A Detailed Analysis of the Morphology of Fibrils of Selectively Mutated Amyloid β (1-40).

Adler J, Baumann M, Voigt B, Scheidt HA, Bhowmik D, Häupl T, Abel B, Madhu PK, Balbach J, Maiti S, Huster D.

Chemphyschem. 2016 Sep 5;17(17):2744-53. doi: 10.1002/cphc.201600413. Epub 2016 Jun 27.

PMID:
27224205
15.

High quality reduced graphene oxide flakes by fast kinetically controlled and clean indirect UV-induced radical reduction.

Flyunt R, Knolle W, Kahnt A, Halbig CE, Lotnyk A, Häupl T, Prager A, Eigler S, Abel B.

Nanoscale. 2016 Apr 14;8(14):7572-9. doi: 10.1039/c6nr00156d.

PMID:
26984451
16.

Effects of PVA-coated nanoparticles on human T helper cell activity.

Strehl C, Schellmann S, Maurizi L, Hofmann-Amtenbrink M, Häupl T, Hofmann H, Buttgereit F, Gaber T.

Toxicol Lett. 2016 Mar 14;245:52-8. doi: 10.1016/j.toxlet.2016.01.003. Epub 2016 Jan 13.

PMID:
26774940
17.

Minor salivary gland carcinoma: a review of 35 cases.

Haymerle G, Schneider S, Harris L, Häupl T, Schopper C, Pammer J, Grasl MCh, Erovic BM.

Eur Arch Otorhinolaryngol. 2016 Sep;273(9):2717-26. doi: 10.1007/s00405-015-3805-4. Epub 2015 Oct 23.

PMID:
26498950
18.

[Biomarkers for prognosis of response to anti-TNF therapy of rheumatoid arthritis: Where do we stand?].

Stuhlmüller B, Skriner K, Häupl T.

Z Rheumatol. 2015 Nov;74(9):812-8. doi: 10.1007/s00393-014-1543-4. Review. German. No abstract available.

PMID:
26347122
19.

Effects of PVA coated nanoparticles on human immune cells.

Strehl C, Gaber T, Maurizi L, Hahne M, Rauch R, Hoff P, Häupl T, Hofmann-Amtenbrink M, Poole AR, Hofmann H, Buttgereit F.

Int J Nanomedicine. 2015 May 8;10:3429-45. doi: 10.2147/IJN.S75936. eCollection 2015.

20.

immunoClust--An automated analysis pipeline for the identification of immunophenotypic signatures in high-dimensional cytometric datasets.

Sörensen T, Baumgart S, Durek P, Grützkau A, Häupl T.

Cytometry A. 2015 Jul;87(7):603-15. doi: 10.1002/cyto.a.22626. Epub 2015 Apr 7.

21.

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF.

Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22.

22.

Intermediates caught in the act: tracing insulin amyloid fibril formation in time by combined optical spectroscopy, light scattering, mass spectrometry and microscopy.

Gladytz A, Lugovoy E, Charvat A, Häupl T, Siefermann KR, Abel B.

Phys Chem Chem Phys. 2015 Jan 14;17(2):918-27. doi: 10.1039/c4cp03072a. Epub 2014 Nov 18.

PMID:
25408431
23.

Chemical modification of a tetrapyrrole-type photosensitizer: tuning application and photochemical action beyond the singlet oxygen channel.

Riyad YM, Naumov S, Schastak S, Griebel J, Kahnt A, Häupl T, Neuhaus J, Abel B, Hermann R.

J Phys Chem B. 2014 Oct 9;118(40):11646-58. doi: 10.1021/jp507270k. Epub 2014 Sep 26.

PMID:
25207950
24.

Angiotensin converting enzyme intron 16 insertion/deletion genotype is associated with plasma C-reactive protein concentration in uteroplacental dysfunction.

Häupl T, Zimmermann M, Kalus U, Yürek S, Koscielny J, Hoppe B.

J Renin Angiotensin Aldosterone Syst. 2015 Jun;16(2):422-7. doi: 10.1177/1470320314539181. Epub 2014 Aug 25.

PMID:
25155623
25.

Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ.

Ghannam K, Martinez-Gamboa L, Spengler L, Krause S, Smiljanovic B, Bonin M, Bhattarai S, Grützkau A, Burmester GR, Häupl T, Feist E.

PLoS One. 2014 Aug 6;9(8):e104048. doi: 10.1371/journal.pone.0104048. eCollection 2014.

26.

Novel application of multi-stimuli network inference to synovial fibroblasts of rheumatoid arthritis patients.

Kupfer P, Huber R, Weber M, Vlaic S, Häupl T, Koczan D, Guthke R, Kinne RW.

BMC Med Genomics. 2014 Jul 3;7:40. doi: 10.1186/1755-8794-7-40.

27.

Identification of rheumatoid arthritis and osteoarthritis patients by transcriptome-based rule set generation.

Woetzel D, Huber R, Kupfer P, Pohlers D, Pfaff M, Driesch D, Häupl T, Koczan D, Stiehl P, Guthke R, Kinne RW.

Arthritis Res Ther. 2014 Apr 1;16(2):R84. doi: 10.1186/ar4526.

28.

The influence of the ΔK280 mutation and N- or C-terminal extensions on the structure, dynamics, and fibril morphology of the tau R2 repeat.

Raz Y, Adler J, Vogel A, Scheidt HA, Häupl T, Abel B, Huster D, Miller Y.

Phys Chem Chem Phys. 2014 May 7;16(17):7710-7. doi: 10.1039/c3cp54890b.

PMID:
24448233
29.

Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Kyogoku C, Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Häupl T, Hiepe F, Alexander T, Radbruch A, Grützkau A.

PLoS One. 2013 Dec 31;8(12):e83776. doi: 10.1371/journal.pone.0083776. eCollection 2013.

30.

Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis.

Ullah M, Stich S, Häupl T, Eucker J, Sittinger M, Ringe J.

PLoS One. 2013 Jul 26;8(7):e69754. doi: 10.1371/journal.pone.0069754. Print 2013.

31.

[New aspects on the pathogenesis of myositis].

Stuhlmüller B, Feist E, Häupl T, Burmester GR, Pipitone N.

Z Rheumatol. 2013 Apr;72(3):209-19. doi: 10.1007/s00393-012-1078-5. German.

PMID:
23515563
32.

The physiologic increase in expression of some type I IFN-inducible genes during pregnancy is not associated with improved disease activity in pregnant patients with rheumatoid arthritis.

Weix J, Häupl T, Raio L, Villiger PM, Förger F.

Transl Res. 2013 Jun;161(6):505-12. doi: 10.1016/j.trsl.2013.02.007. Epub 2013 Mar 16.

PMID:
23507374
33.

[Biomarkers and personalized medicine].

Scherer HU, Burmester GR, Häupl T.

Z Rheumatol. 2013 Feb;72(1):20-6. doi: 10.1007/s00393-011-0884-5. German.

PMID:
23223890
34.

Biocompatible silicon surfaces through orthogonal click chemistries and a high affinity silicon oxide binding peptide.

Hassert R, Pagel M, Ming Z, Häupl T, Abel B, Braun K, Wiessler M, Beck-Sickinger AG.

Bioconjug Chem. 2012 Oct 17;23(10):2129-37. doi: 10.1021/bc3003875. Epub 2012 Sep 27.

PMID:
22989005
35.

The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.

Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A.

J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19.

PMID:
22610275
36.

[Biomarkers in rheumatology. Biomarkers and imaging for the diagnosis and stratification of rheumatoid arthritis and spondylarthritis in the ArthroMark network funded by the Federal Ministry of Education and Research].

Häupl T, Appel H, Backhaus M, Burkhardt H, Grünke M, Grützkau A, Hoppe B, Listing J, Ostendorf B, Rudwaleit M, Sieper J, Skapenko A, Skriner K, Sörensen T, Stuhlmüller B, Zink A, Schulze-Koops H, Burmester GR.

Z Rheumatol. 2012 Jun;71(4):314-8. doi: 10.1007/s00393-011-0781-y. German.

PMID:
22546912
37.

Chondrogenic differentiation of human subchondral progenitor cells is affected by synovial fluid from donors with osteoarthritis or rheumatoid arthritis.

Krüger JP, Endres M, Neumann K, Stuhlmüller B, Morawietz L, Häupl T, Kaps C.

J Orthop Surg Res. 2012 Mar 13;7:10. doi: 10.1186/1749-799X-7-10.

38.

Downregulation of ErbB3 by Wnt3a contributes to wnt-induced osteoblast differentiation in mesenchymal cells.

Jullien N, Maudinet A, Leloutre B, Ringe J, Häupl T, Marie PJ.

J Cell Biochem. 2012 Jun;113(6):2047-56. doi: 10.1002/jcb.24076.

PMID:
22274864
39.

Fibrinogen and factor XIII A-subunit genotypes interactively influence C-reactive protein levels during inflammation.

Hoppe B, Häupl T, Skapenko A, Ziemer S, Tauber R, Salama A, Schulze-Koops H, Burmester GR, Dörner T.

Ann Rheum Dis. 2012 Jul;71(7):1163-9. doi: 10.1136/annrheumdis-2011-200738. Epub 2012 Jan 20.

PMID:
22267327
40.
41.

Prothrombin 20210G>A genotype and C-reactive protein level.

Hoppe B, Burmester GR, Häupl T.

Blood. 2011 Oct 20;118(16):4495-6. doi: 10.1182/blood-2011-08-373928. No abstract available.

42.

[DNA microarrays].

Biesen R, Häupl T.

Z Rheumatol. 2011 Nov;70(9):803-6, 808. doi: 10.1007/s00393-011-0869-4. German.

PMID:
21956826
43.

Differential gene expression profiling of human bone marrow-derived mesenchymal stem cells during adipogenic development.

Menssen A, Häupl T, Sittinger M, Delorme B, Charbord P, Ringe J.

BMC Genomics. 2011 Sep 24;12:461. doi: 10.1186/1471-2164-12-461.

44.

Transcriptional profiling of the hematopoietic support of interleukin-stimulated human umbilical vein endothelial cells (HUVECs).

Bal G, Kamhieh-Milz J, Futschik M, Häupl T, Salama A, Moldenhauer A.

Cell Transplant. 2012;21(1):251-67. doi: 10.3727/096368911X580581. Epub 2011 Jun 7.

PMID:
21669038
45.
46.

Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions).

Shahab-Osterloh S, Witte F, Hoffmann A, Winkel A, Laggies S, Neumann B, Seiffart V, Lindenmaier W, Gruber AD, Ringe J, Häupl T, Thorey F, Willbold E, Corbeau P, Gross G.

Stem Cells. 2010 Sep;28(9):1590-601. doi: 10.1002/stem.487.

47.

Quantitative determination of the diagnostic accuracy of the synovitis score and its components.

Slansky E, Li J, Häupl T, Morawietz L, Krenn V, Pessler F.

Histopathology. 2010 Sep;57(3):436-43. doi: 10.1111/j.1365-2559.2010.03641.x.

PMID:
20840673
48.

Chemokine profile of synovial fluid from normal, osteoarthritis and rheumatoid arthritis patients: CCL25, CXCL10 and XCL1 recruit human subchondral mesenchymal progenitor cells.

Endres M, Andreas K, Kalwitz G, Freymann U, Neumann K, Ringe J, Sittinger M, Häupl T, Kaps C.

Osteoarthritis Cartilage. 2010 Nov;18(11):1458-66. doi: 10.1016/j.joca.2010.08.003. Epub 2010 Aug 13.

49.

Defining TNF-α- and LPS-induced gene signatures in monocytes to unravel the complexity of peripheral blood transcriptomes in health and disease.

Smiljanovic B, Grün JR, Steinbrich-Zöllner M, Stuhlmüller B, Häupl T, Burmester GR, Radbruch A, Grützkau A, Baumgrass R.

J Mol Med (Berl). 2010 Oct;88(10):1065-79. doi: 10.1007/s00109-010-0648-8. Epub 2010 Jul 17.

PMID:
20640394
50.

Novel markers of mesenchymal stem cells defined by genome-wide gene expression analysis of stromal cells from different sources.

Kaltz N, Ringe J, Holzwarth C, Charbord P, Niemeyer M, Jacobs VR, Peschel C, Häupl T, Oostendorp RA.

Exp Cell Res. 2010 Oct 1;316(16):2609-17. doi: 10.1016/j.yexcr.2010.06.002. Epub 2010 Jun 18.

PMID:
20599957

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