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Items: 1 to 50 of 279

1.

Regional myocardial strain measurements from 4DCT in patients with normal LV function.

McVeigh ER, Pourmorteza A, Guttman M, Sandfort V, Contijoch F, Budhiraja S, Chen Z, Bluemke DA, Chen MY.

J Cardiovasc Comput Tomogr. 2018 May 9. pii: S1934-5925(18)30092-3. doi: 10.1016/j.jcct.2018.05.002. [Epub ahead of print]

PMID:
29784623
2.

The Promise of Telemedicine for Movement Disorders: an Interdisciplinary Approach.

Ben-Pazi H, Browne P, Chan P, Cubo E, Guttman M, Hassan A, Hatcher-Martin J, Mari Z, Moukheiber E, Okubadejo NU, Shalash A; International Parkinson and Movement Disorder Society Telemedicine Task Force.

Curr Neurol Neurosci Rep. 2018 Apr 13;18(5):26. doi: 10.1007/s11910-018-0834-6. Review.

PMID:
29654523
3.

Telemedicine Use for Movement Disorders: A Global Survey.

Hassan A, Dorsey ER, Goetz CG, Bloem BR, Guttman M, Tanner CM, Mari Z, Pantelyat A, Galifianakis NB, Bajwa JA, Gatto EM, Cubo E.

Telemed J E Health. 2018 Mar 22. doi: 10.1089/tmj.2017.0295. [Epub ahead of print]

PMID:
29565764
4.

Conformational dynamics of P-glycoprotein in lipid nanodiscs and detergent micelles reveal complex motions on a wide time scale.

Li MJ, Guttman M, Atkins WM.

J Biol Chem. 2018 Apr 27;293(17):6297-6307. doi: 10.1074/jbc.RA118.002190. Epub 2018 Mar 6.

PMID:
29511086
5.

Bridging the structural gap of glycoproteomics with ion mobility spectrometry.

Mookherjee A, Guttman M.

Curr Opin Chem Biol. 2018 Feb;42:86-92. doi: 10.1016/j.cbpa.2017.11.012. Epub 2017 Dec 1. Review.

PMID:
29202341
6.

Corrigendum: The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Dec 14;552(7684):278. doi: 10.1038/nature24667. Epub 2017 Nov 22.

PMID:
29168505
7.

RAP-MS: A Method to Identify Proteins that Interact Directly with a Specific RNA Molecule in Cells.

McHugh CA, Guttman M.

Methods Mol Biol. 2018;1649:473-488. doi: 10.1007/978-1-4939-7213-5_31.

PMID:
29130217
8.

Telemedicine Enables Broader Access to Movement Disorders Curricula for Medical Students.

Cubo E, Doumbe J, López E, Lopez GA, Gatto E, Persi G, Guttman M.

Tremor Other Hyperkinet Mov (N Y). 2017 Oct 19;7:501. doi: 10.7916/D8708CXW. eCollection 2017.

9.

Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders.

Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ.

Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172.

PMID:
29050386
10.

The 4D nucleome project.

Dekker J, Belmont AS, Guttman M, Leshyk VO, Lis JT, Lomvardas S, Mirny LA, O'Shea CC, Park PJ, Ren B, Politz JCR, Shendure J, Zhong S; 4D Nucleome Network.

Nature. 2017 Sep 13;549(7671):219-226. doi: 10.1038/nature23884. Erratum in: Nature. 2017 Nov 22;:.

11.

Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization.

Torrents de la Peña A, Julien JP, de Taeye SW, Garces F, Guttman M, Ozorowski G, Pritchard LK, Behrens AJ, Go EP, Burger JA, Schermer EE, Sliepen K, Ketas TJ, Pugach P, Yasmeen A, Cottrell CA, Torres JL, Vavourakis CD, van Gils MJ, LaBranche C, Montefiori DC, Desaire H, Crispin M, Klasse PJ, Lee KK, Moore JP, Ward AB, Wilson IA, Sanders RW.

Cell Rep. 2017 Aug 22;20(8):1805-1817. doi: 10.1016/j.celrep.2017.07.077.

12.

Extracellular Matrix Proteins Mediate HIV-1 gp120 Interactions with α4β7.

Plotnik D, Guo W, Cleveland B, von Haller P, Eng JK, Guttman M, Lee KK, Arthos J, Hu SL.

J Virol. 2017 Oct 13;91(21). pii: e01005-17. doi: 10.1128/JVI.01005-17. Print 2017 Nov 1.

13.

Response to Comment on "Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing".

Chen CK, Chow A, Lai M, Guttman M.

Science. 2017 Jun 16;356(6343). pii: eaam5439. doi: 10.1126/science.aam5439.

PMID:
28619888
14.

Non-contrast-enhanced T1 -weighted MRI of myocardial radiofrequency ablation lesions.

Guttman MA, Tao S, Fink S, Kolandaivelu A, Halperin HR, Herzka DA.

Magn Reson Med. 2018 Feb;79(2):879-889. doi: 10.1002/mrm.26750. Epub 2017 May 11.

15.

Serotonin and dopamine transporter PET changes in the premotor phase of LRRK2 parkinsonism: cross-sectional studies.

Wile DJ, Agarwal PA, Schulzer M, Mak E, Dinelle K, Shahinfard E, Vafai N, Hasegawa K, Zhang J, McKenzie J, Neilson N, Strongosky A, Uitti RJ, Guttman M, Zabetian CP, Ding YS, Adam M, Aasly J, Wszolek ZK, Farrer M, Sossi V, Stoessl AJ.

Lancet Neurol. 2017 May;16(5):351-359. doi: 10.1016/S1474-4422(17)30056-X. Epub 2017 Mar 20.

16.

Gas-Phase Hydrogen/Deuterium Exchange for Distinguishing Isomeric Carbohydrate Ions.

Uppal SS, Beasley SE, Scian M, Guttman M.

Anal Chem. 2017 Apr 18;89(8):4737-4742. doi: 10.1021/acs.analchem.7b00683. Epub 2017 Mar 29.

PMID:
28304155
17.

Re-evaluating the foundations of lncRNA-Polycomb function.

Blanco MR, Guttman M.

EMBO J. 2017 Apr 13;36(8):964-966. doi: 10.15252/embj.201796796. Epub 2017 Mar 15. No abstract available.

18.

Linking Protein and RNA Function within the Same Gene.

Szempruch A, Guttman M.

Cell. 2017 Feb 23;168(5):753-755. doi: 10.1016/j.cell.2017.02.014.

19.

Quantitative predictions of protein interactions with long noncoding RNAs.

Cirillo D, Blanco M, Armaos A, Buness A, Avner P, Guttman M, Cerase A, Tartaglia GG.

Nat Methods. 2016 Dec 29;14(1):5-6. doi: 10.1038/nmeth.4100. No abstract available.

PMID:
28032625
20.

A randomized, double-blind, placebo-controlled trial of coenzyme Q10 in Huntington disease.

McGarry A, McDermott M, Kieburtz K, de Blieck EA, Beal F, Marder K, Ross C, Shoulson I, Gilbert P, Mallonee WM, Guttman M, Wojcieszek J, Kumar R, LeDoux MS, Jenkins M, Rosas HD, Nance M, Biglan K, Como P, Dubinsky RM, Shannon KM, O'Suilleabhain P, Chou K, Walker F, Martin W, Wheelock VL, McCusker E, Jankovic J, Singer C, Sanchez-Ramos J, Scott B, Suchowersky O, Factor SA, Higgins DS Jr, Molho E, Revilla F, Caviness JN, Friedman JH, Perlmutter JS, Feigin A, Anderson K, Rodriguez R, McFarland NR, Margolis RL, Farbman ES, Raymond LA, Suski V, Kostyk S, Colcher A, Seeberger L, Epping E, Esmail S, Diaz N, Fung WL, Diamond A, Frank S, Hanna P, Hermanowicz N, Dure LS, Cudkowicz M; Huntington Study Group 2CARE Investigators and Coordinators.

Neurology. 2017 Jan 10;88(2):152-159. doi: 10.1212/WNL.0000000000003478. Epub 2016 Dec 2.

21.

Regular Exercise, Quality of Life, and Mobility in Parkinson's Disease: A Longitudinal Analysis of National Parkinson Foundation Quality Improvement Initiative Data.

Rafferty MR, Schmidt PN, Luo ST, Li K, Marras C, Davis TL, Guttman M, Cubillos F, Simuni T; all NPF-QII Investigators.

J Parkinsons Dis. 2017;7(1):193-202. doi: 10.3233/JPD-160912.

22.

Local regulation of gene expression by lncRNA promoters, transcription and splicing.

Engreitz JM, Haines JE, Perez EM, Munson G, Chen J, Kane M, McDonel PE, Guttman M, Lander ES.

Nature. 2016 Nov 17;539(7629):452-455. doi: 10.1038/nature20149. Epub 2016 Oct 26.

PMID:
27783602
23.

Long non-coding RNAs: spatial amplifiers that control nuclear structure and gene expression.

Engreitz JM, Ollikainen N, Guttman M.

Nat Rev Mol Cell Biol. 2016 Dec;17(12):756-770. doi: 10.1038/nrm.2016.126. Epub 2016 Oct 26. Review.

PMID:
27780979
24.

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing.

Chen CK, Blanco M, Jackson C, Aznauryan E, Ollikainen N, Surka C, Chow A, Cerase A, McDonel P, Guttman M.

Science. 2016 Oct 28;354(6311):468-472. Epub 2016 Aug 4.

PMID:
27492478
25.

A Magnetic Resonance Imaging-Conditional External Cardiac Defibrillator for Resuscitation Within the Magnetic Resonance Imaging Scanner Bore.

Schmidt EJ, Watkins RD, Zviman MM, Guttman MA, Wang W, Halperin HA.

Circ Cardiovasc Imaging. 2016 Oct;9(10). pii: e005091.

26.

Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C.

Klasse PJ, LaBranche CC, Ketas TJ, Ozorowski G, Cupo A, Pugach P, Ringe RP, Golabek M, van Gils MJ, Guttman M, Lee KK, Wilson IA, Butera ST, Ward AB, Montefiori DC, Sanders RW, Moore JP.

PLoS Pathog. 2016 Sep 14;12(9):e1005864. doi: 10.1371/journal.ppat.1005864. eCollection 2016 Sep.

27.

m(6)A RNA methylation promotes XIST-mediated transcriptional repression.

Patil DP, Chen CK, Pickering BF, Chow A, Jackson C, Guttman M, Jaffrey SR.

Nature. 2016 Sep 15;537(7620):369-373. doi: 10.1038/nature19342. Epub 2016 Sep 7.

28.

Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates.

Verkerke HP, Williams JA, Guttman M, Simonich CA, Liang Y, Filipavicius M, Hu SL, Overbaugh J, Lee KK.

J Virol. 2016 Sep 29;90(20):9471-82. doi: 10.1128/JVI.01351-16. Print 2016 Oct 15.

29.

The Myeloablative Drug Busulfan Converts Cysteine to Dehydroalanine and Lanthionine in Redoxins.

Scian M, Guttman M, Bouldin SD, Outten CE, Atkins WM.

Biochemistry. 2016 Aug 23;55(33):4720-30. doi: 10.1021/acs.biochem.6b00622. Epub 2016 Aug 11.

30.

Changes in Structure and Antigenicity of HIV-1 Env Trimers Resulting from Removal of a Conserved CD4 Binding Site-Proximal Glycan.

Liang Y, Guttman M, Williams JA, Verkerke H, Alvarado D, Hu SL, Lee KK.

J Virol. 2016 Sep 29;90(20):9224-36. doi: 10.1128/JVI.01116-16. Print 2016 Oct 15.

31.

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Joyce MG, Zhang B, Ou L, Chen M, Chuang GY, Druz A, Kong WP, Lai YT, Rundlet EJ, Tsybovsky Y, Yang Y, Georgiev IS, Guttman M, Lees CR, Pancera M, Sastry M, Soto C, Stewart-Jones GBE, Thomas PV, Van Galen JG, Baxa U, Lee KK, Mascola JR, Graham BS, Kwong PD.

Nat Struct Mol Biol. 2016 Sep;23(9):811-820. doi: 10.1038/nsmb.3267. Epub 2016 Aug 1.

32.

Somatic Hypermutation-Induced Changes in the Structure and Dynamics of HIV-1 Broadly Neutralizing Antibodies.

Davenport TM, Gorman J, Joyce MG, Zhou T, Soto C, Guttman M, Moquin S, Yang Y, Zhang B, Doria-Rose NA, Hu SL, Mascola JR, Kwong PD, Lee KK.

Structure. 2016 Aug 2;24(8):1346-1357. doi: 10.1016/j.str.2016.06.012. Epub 2016 Jul 28.

33.

Health Care Delivery Practices in Huntington's Disease Specialty Clinics: An International Survey.

Frich JC, Rae D, Roxburgh R, Miedzybrodzka ZH, Edmondson M, Pope EB, Goodman L, Haddad MS, Giuliano J, Nelson EC, Guttman M, Nance M.

J Huntingtons Dis. 2016 Jun 27;5(2):207-13. doi: 10.3233/JHD-160192.

34.

Longitudinal Changes in the Motor Learning-Related Brain Activation Response in Presymptomatic Huntington's Disease.

Holtbernd F, Tang CC, Feigin A, Dhawan V, Ghilardi MF, Paulsen JS, Guttman M, Eidelberg D.

PLoS One. 2016 May 18;11(5):e0154742. doi: 10.1371/journal.pone.0154742. eCollection 2016.

35.

Site-Specific Mapping of Sialic Acid Linkage Isomers by Ion Mobility Spectrometry.

Guttman M, Lee KK.

Anal Chem. 2016 May 17;88(10):5212-7. doi: 10.1021/acs.analchem.6b00265. Epub 2016 May 2.

36.

A Guide to Packing Your DNA.

Dekker J, Guttman M, Lomvardas S.

Cell. 2016 Apr 7;165(2):259-61. doi: 10.1016/j.cell.2016.03.039.

37.

Robust transcriptome-wide discovery of RNA-binding protein binding sites with enhanced CLIP (eCLIP).

Van Nostrand EL, Pratt GA, Shishkin AA, Gelboin-Burkhart C, Fang MY, Sundararaman B, Blue SM, Nguyen TB, Surka C, Elkins K, Stanton R, Rigo F, Guttman M, Yeo GW.

Nat Methods. 2016 Jun;13(6):508-14. doi: 10.1038/nmeth.3810. Epub 2016 Mar 28.

38.

Probing the Impact of Local Structural Dynamics of Conformational Epitopes on Antibody Recognition.

Liang Y, Guttman M, Davenport TM, Hu SL, Lee KK.

Biochemistry. 2016 Apr 19;55(15):2197-213. doi: 10.1021/acs.biochem.5b01354. Epub 2016 Apr 4.

39.

Evolutionary analysis across mammals reveals distinct classes of long non-coding RNAs.

Chen J, Shishkin AA, Zhu X, Kadri S, Maza I, Guttman M, Hanna JH, Regev A, Garber M.

Genome Biol. 2016 Feb 2;17:19. doi: 10.1186/s13059-016-0880-9.

40.

Membrane Interactions, Ligand-Dependent Dynamics, and Stability of Cytochrome P4503A4 in Lipid Nanodiscs.

Treuheit NA, Redhair M, Kwon H, McClary WD, Guttman M, Sumida JP, Atkins WM.

Biochemistry. 2016 Feb 23;55(7):1058-69. doi: 10.1021/acs.biochem.5b01313. Epub 2016 Feb 8.

41.

Tuning a High Transmission Ion Guide to Prevent Gas-Phase Proton Exchange During H/D Exchange MS Analysis.

Guttman M, Wales TE, Whittington D, Engen JR, Brown JM, Lee KK.

J Am Soc Mass Spectrom. 2016 Apr;27(4):662-8. doi: 10.1007/s13361-015-1330-8. Epub 2016 Jan 26.

42.

Isotope Labeling of Biomolecules: Structural Analysis of Viruses by HDX-MS.

Guttman M, Lee KK.

Methods Enzymol. 2016;566:405-26. doi: 10.1016/bs.mie.2015.05.021. Epub 2015 Jul 4.

43.

D3 dopamine receptor-preferring [11C]PHNO PET imaging in Parkinson patients with dyskinesia.

Payer DE, Guttman M, Kish SJ, Tong J, Adams JR, Rusjan P, Houle S, Furukawa Y, Wilson AA, Boileau I.

Neurology. 2016 Jan 19;86(3):224-30. doi: 10.1212/WNL.0000000000002285. Epub 2015 Dec 30.

44.

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design.

Gorman J, Soto C, Yang MM, Davenport TM, Guttman M, Bailer RT, Chambers M, Chuang GY, DeKosky BJ, Doria-Rose NA, Druz A, Ernandes MJ, Georgiev IS, Jarosinski MC, Joyce MG, Lemmin TM, Leung S, Louder MK, McDaniel JR, Narpala S, Pancera M, Stuckey J, Wu X, Yang Y, Zhang B, Zhou T; NISC Comparative Sequencing Program, Mullikin JC, Baxa U, Georgiou G, McDermott AB, Bonsignori M, Haynes BF, Moore PL, Morris L, Lee KK, Shapiro L, Mascola JR, Kwong PD.

Nat Struct Mol Biol. 2016 Jan;23(1):81-90. doi: 10.1038/nsmb.3144. Epub 2015 Dec 21.

45.

Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes.

de Taeye SW, Ozorowski G, Torrents de la Peña A, Guttman M, Julien JP, van den Kerkhof TL, Burger JA, Pritchard LK, Pugach P, Yasmeen A, Crampton J, Hu J, Bontjer I, Torres JL, Arendt H, DeStefano J, Koff WC, Schuitemaker H, Eggink D, Berkhout B, Dean H, LaBranche C, Crotty S, Crispin M, Montefiori DC, Klasse PJ, Lee KK, Moore JP, Wilson IA, Ward AB, Sanders RW.

Cell. 2015 Dec 17;163(7):1702-15. doi: 10.1016/j.cell.2015.11.056.

46.

Clinical-Genetic Associations in the Prospective Huntington at Risk Observational Study (PHAROS): Implications for Clinical Trials.

Huntington Study Group PHAROS Investigators, Biglan KM, Shoulson I, Kieburtz K, Oakes D, Kayson E, Shinaman MA, Zhao H, Romer M, Young A, Hersch S, Penney J, Marder K, Paulsen J, Quaid K, Siemers E, Tanner C, Mallonee W, Suter G, Dubinsky R, Gray C, Nance M, Bundlie S, Radtke D, Kostyk S, Baic C, Caress J, Walker F, Hunt V, O'Neill C, Chouinard S, Factor S, Greenamyre T, Wood-Siverio C, Corey-Bloom J, Song D, Peavy G, Moskowitz C, Wesson M, Samii A, Bird T, Lipe H, Blindauer K, Marshall F, Zimmerman C, Goldstein J, Rosas D, Novak P, Caviness J, Adler C, Duffy A, Wheelock V, Tempkin T, Richman D, Seeberger L, Albin R, Chou KL, Racette B, Perlmutter JS, Perlman S, Bordelon Y, Martin W, Wieler M, Leavitt B, Raymond L, Decolongon J, Clarke L, Jankovic J, Hunter C, Hauser RA, Sanchez-Ramos J, Furtado S, Suchowersky O, Klimek ML, Guttman M, Sethna R, Feigin A, Cox M, Shannon B, Percy A, Dure L, Harrison M, Johnson W, Higgins D, Molho E, Nickerson C, Evans S, Hobson D, Singer C, Galvez-Jimenez N, Shannon K, Comella C, Ross C, Saint-Hilaire MH, Testa C, Rosenblatt A, Hogarth P, Weiner W, Como P, Kumar R, Cotto C, Stout J, Brocht A, Watts A, Eberly S, Weaver C, Foroud T, Gusella J, MacDonald M, Myers R, Fahn S, Shults C.

JAMA Neurol. 2016 Jan;73(1):102-10. doi: 10.1001/jamaneurol.2015.2736.

PMID:
26569098
47.

Local and global structural drivers for the photoactivation of the orange carotenoid protein.

Gupta S, Guttman M, Leverenz RL, Zhumadilova K, Pawlowski EG, Petzold CJ, Lee KK, Ralston CY, Kerfeld CA.

Proc Natl Acad Sci U S A. 2015 Oct 13;112(41):E5567-74. doi: 10.1073/pnas.1512240112. Epub 2015 Sep 18.

48.

Influences on the Design and Purification of Soluble, Recombinant Native-Like HIV-1 Envelope Glycoprotein Trimers.

Ringe RP, Yasmeen A, Ozorowski G, Go EP, Pritchard LK, Guttman M, Ketas TA, Cottrell CA, Wilson IA, Sanders RW, Cupo A, Crispin M, Lee KK, Desaire H, Ward AB, Klasse PJ, Moore JP.

J Virol. 2015 Dec;89(23):12189-210. doi: 10.1128/JVI.01768-15. Epub 2015 Aug 26.

49.

The NIH BD2K center for big data in translational genomics.

Paten B, Diekhans M, Druker BJ, Friend S, Guinney J, Gassner N, Guttman M, Kent WJ, Mantey P, Margolin AA, Massie M, Novak AM, Nothaft F, Pachter L, Patterson D, Smuga-Otto M, Stuart JM, Van't Veer L, Wold B, Haussler D.

J Am Med Inform Assoc. 2015 Nov;22(6):1143-7. doi: 10.1093/jamia/ocv047. Epub 2015 Jul 13.

50.

Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation.

Tong J, Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ.

Neurobiol Dis. 2015 Oct;82:243-253. doi: 10.1016/j.nbd.2015.06.010. Epub 2015 Jun 21.

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