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Items: 1 to 50 of 54

1.

FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression.

Hornsveld M, Smits LMM, Meerlo M, van Amersfoort M, Groot Koerkamp MJA, van Leenen D, Kloet DEA, Holstege FCP, Derksen PWB, Burgering BMT, Dansen TB.

Cancer Res. 2018 Feb 12. doi: 10.1158/0008-5472.CAN-17-2511. [Epub ahead of print]

PMID:
29440168
2.

Growth plate expression profiling: Large and small breed dogs provide new insights in endochondral bone formation.

Teunissen M, Riemers FM, van Leenen D, Groot Koerkamp MJA, Meij BP, Alblas J, Penning LC, Miranda-Bedate A, Tryfonidou MA.

J Orthop Res. 2018 Jan;36(1):138-148. doi: 10.1002/jor.23647. Epub 2017 Aug 14.

3.

EBV MicroRNA BART16 Suppresses Type I IFN Signaling.

Hooykaas MJG, van Gent M, Soppe JA, Kruse E, Boer IGJ, van Leenen D, Groot Koerkamp MJA, Holstege FCP, Ressing ME, Wiertz EJHJ, Lebbink RJ.

J Immunol. 2017 May 15;198(10):4062-4073. doi: 10.4049/jimmunol.1501605. Epub 2017 Apr 17.

PMID:
28416598
4.

Characterization of bovine embryos cultured under conditions appropriate for sustaining human naïve pluripotency.

Brinkhof B, van Tol HT, Groot Koerkamp MJ, Wubbolts RW, Haagsman HP, Roelen BA.

PLoS One. 2017 Feb 27;12(2):e0172920. doi: 10.1371/journal.pone.0172920. eCollection 2017.

5.

Molecular mechanisms that distinguish TFIID housekeeping from regulatable SAGA promoters.

de Jonge WJ, O'Duibhir E, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Kemmeren P, Holstege FC.

EMBO J. 2017 Feb 1;36(3):274-290. doi: 10.15252/embj.201695621. Epub 2016 Dec 15.

6.

FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development.

Paap RH, Oosterbroek S, Wagemans CM, von Oerthel L, Schellevis RD, Vastenhouw-van der Linden AJ, Groot Koerkamp MJ, Hoekman MF, Smidt MP.

Proc Natl Acad Sci U S A. 2016 Oct 24. pii: 201609111. [Epub ahead of print]

7.

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

Hessel EV, van Lith HA, Wolterink-Donselaar IG, de Wit M, Groot Koerkamp MJ, Holstege FC, Kas MJ, Fernandes C, de Graan PN.

Eur J Neurosci. 2016 Dec;44(11):2950-2957. doi: 10.1111/ejn.13420.

PMID:
27690330
8.

Expression of ERAP2 and LST1 is increased before start of therapy in rheumatoid arthritis patients with good clinical response to glucocorticoids.

Fritsch-Stork RD, Silva-Cardoso SC, Groot Koerkamp MJ, Broen JC, Lafeber FF, Bijlsma JW.

Clin Exp Rheumatol. 2016 Jul-Aug;34(4):685-9. Epub 2016 Jun 22.

PMID:
27384923
9.

An endometrial gene expression signature accurately predicts recurrent implantation failure after IVF.

Koot YE, van Hooff SR, Boomsma CM, van Leenen D, Groot Koerkamp MJ, Goddijn M, Eijkemans MJ, Fauser BC, Holstege FC, Macklon NS.

Sci Rep. 2016 Jan 22;6:19411. doi: 10.1038/srep19411.

10.

A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.

Sameith K, Amini S, Groot Koerkamp MJ, van Leenen D, Brok M, Brabers N, Lijnzaad P, van Hooff SR, Benschop JJ, Lenstra TL, Apweiler E, van Wageningen S, Snel B, Holstege FC, Kemmeren P.

BMC Biol. 2015 Dec 23;13:112. doi: 10.1186/s12915-015-0222-5.

11.

Expression Profiling after Prolonged Experimental Febrile Seizures in Mice Suggests Structural Remodeling in the Hippocampus.

Jongbloets BC, van Gassen KL, Kan AA, Olde Engberink AH, de Wit M, Wolterink-Donselaar IG, Groot Koerkamp MJ, van Nieuwenhuizen O, Holstege FC, de Graan PN.

PLoS One. 2015 Dec 18;10(12):e0145247. doi: 10.1371/journal.pone.0145247. eCollection 2015.

12.

Genome-wide analysis reveals NRP1 as a direct HIF1α-E2F7 target in the regulation of motorneuron guidance in vivo.

de Bruin A, A Cornelissen PW, Kirchmaier BC, Mokry M, Iich E, Nirmala E, Liang KH, D Végh AM, Scholman KT, Groot Koerkamp MJ, Holstege FC, Cuppen E, Schulte-Merker S, Bakker WJ.

Nucleic Acids Res. 2016 May 5;44(8):3549-66. doi: 10.1093/nar/gkv1471. Epub 2015 Dec 17.

13.

FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1).

Kloet DE, Polderman PE, Eijkelenboom A, Smits LM, van Triest MH, van den Berg MC, Groot Koerkamp MJ, van Leenen D, Lijnzaad P, Holstege FC, Burgering BM.

Biochem J. 2015 Jul 15;469(2):289-98. doi: 10.1042/BJ20140831. Epub 2015 May 20.

14.

A mRNA landscape of bovine embryos after standard and MAPK-inhibited culture conditions: a comparative analysis.

Brinkhof B, van Tol HT, Groot Koerkamp MJ, Riemers FM, IJzer SG, Mashayekhi K, Haagsman HP, Roelen BA.

BMC Genomics. 2015 Apr 10;16:277. doi: 10.1186/s12864-015-1448-x.

15.

Identification of Srp9 as a febrile seizure susceptibility gene.

Hessel EV, de Wit M, Wolterink-Donselaar IG, Karst H, de Graaff E, van Lith HA, de Bruijn E, de Sonnaville S, Verbeek NE, Lindhout D, de Kovel CG, Koeleman BP, van Kempen M, Brilstra E, Cuppen E, Loos M, Spijker SS, Kan AA, Baars SE, van Rijen PC, Gosselaar PH, Groot Koerkamp MJ, Holstege FC, van Duijn C, Vergeer J, Moll HA, Taubøll E, Heuser K, Ramakers GM, Pasterkamp RJ, van Nieuwenhuizen O, Hoogenraad CC, Kas MJ, de Graan PN.

Ann Clin Transl Neurol. 2014 Apr;1(4):239-50. doi: 10.1002/acn3.48. Epub 2014 Mar 12.

16.

The genomic landscape of compensatory evolution.

Szamecz B, Boross G, Kalapis D, Kovács K, Fekete G, Farkas Z, Lázár V, Hrtyan M, Kemmeren P, Groot Koerkamp MJ, Rutkai E, Holstege FC, Papp B, Pál C.

PLoS Biol. 2014 Aug 26;12(8):e1001935. doi: 10.1371/journal.pbio.1001935. eCollection 2014 Aug.

17.

Cell cycle population effects in perturbation studies.

O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC.

Mol Syst Biol. 2014 Jun 21;10:732. doi: 10.15252/msb.20145172.

18.

Aberrant expression and distribution of enzymes of the urea cycle and other ammonia metabolizing pathways in dogs with congenital portosystemic shunts.

van Straten G, van Steenbeek FG, Grinwis GC, Favier RP, Kummeling A, van Gils IH, Fieten H, Groot Koerkamp MJ, Holstege FC, Rothuizen J, Spee B.

PLoS One. 2014 Jun 19;9(6):e100077. doi: 10.1371/journal.pone.0100077. eCollection 2014.

19.

The two main forms of histiocytic sarcoma in the predisposed Flatcoated retriever dog display variation in gene expression.

Boerkamp KM, van Steenbeek FG, Penning LC, Groot Koerkamp MJ, van Leenen D, Vos-Loohuis M, Grinwis GC, Rutteman GR.

PLoS One. 2014 Jun 2;9(6):e98258. doi: 10.1371/journal.pone.0098258. eCollection 2014.

20.

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC.

Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054.

21.

Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.

Roessler R, Smallwood SA, Veenvliet JV, Pechlivanoglou P, Peng SP, Chakrabarty K, Groot-Koerkamp MJ, Pasterkamp RJ, Wesseling E, Kelsey G, Boddeke E, Smidt MP, Copray S.

Stem Cell Reports. 2014 Apr 3;2(4):520-33. doi: 10.1016/j.stemcr.2014.03.001. eCollection 2014 Apr 8.

22.

Translation of branched-chain aminotransferase-1 transcripts is impaired in cells haploinsufficient for ribosomal protein genes.

Pereboom TC, Bondt A, Pallaki P, Klasson TD, Goos YJ, Essers PB, Groot Koerkamp MJ, Gazda HT, Holstege FC, Costa LD, MacInnes AW.

Exp Hematol. 2014 May;42(5):394-403.e4. doi: 10.1016/j.exphem.2013.12.010. Epub 2014 Jan 23.

PMID:
24463277
23.

Elucidation of the distal convoluted tubule transcriptome identifies new candidate genes involved in renal Mg(2+) handling.

de Baaij JH, Groot Koerkamp MJ, Lavrijsen M, van Zeeland F, Meijer H, Holstege FC, Bindels RJ, Hoenderop JG.

Am J Physiol Renal Physiol. 2013 Dec 1;305(11):F1563-73. doi: 10.1152/ajprenal.00322.2013. Epub 2013 Oct 2.

24.

Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2.

Hoekstra EJ, von Oerthel L, van der Heide LP, Kouwenhoven WM, Veenvliet JV, Wever I, Jin YR, Yoon JK, van der Linden AJ, Holstege FC, Groot Koerkamp MJ, Smidt MP.

PLoS One. 2013 Sep 16;8(9):e74049. doi: 10.1371/journal.pone.0074049. eCollection 2013.

25.

Gene expression profiling of histiocytic sarcomas in a canine model: the predisposed flatcoated retriever dog.

Boerkamp KM, van der Kooij M, van Steenbeek FG, van Wolferen ME, Groot Koerkamp MJ, van Leenen D, Grinwis GC, Penning LC, Wiemer EA, Rutteman GR.

PLoS One. 2013 Aug 1;8(8):e71094. doi: 10.1371/journal.pone.0071094. Print 2013.

26.

Balancing of histone H3K4 methylation states by the Kdm5c/SMCX histone demethylase modulates promoter and enhancer function.

Outchkourov NS, Muiño JM, Kaufmann K, van Ijcken WF, Groot Koerkamp MJ, van Leenen D, de Graaf P, Holstege FC, Grosveld FG, Timmers HT.

Cell Rep. 2013 Apr 25;3(4):1071-9. doi: 10.1016/j.celrep.2013.02.030. Epub 2013 Mar 28.

27.

PP035. Genome-wide expression profile of first and second trimester human uterine natural killer cells.

Post Uiterweer ED, Eijkelkamp N, Groot Koerkamp MJ, Peeters LL, Holstege FC, Heijnen CJ, Franx A.

Pregnancy Hypertens. 2013 Apr;3(2):79. doi: 10.1016/j.preghy.2013.04.062. Epub 2013 Jun 6.

PMID:
26105890
28.

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies.

Smolders LA, Meij BP, Onis D, Riemers FM, Bergknut N, Wubbolts R, Grinwis GC, Houweling M, Groot Koerkamp MJ, van Leenen D, Holstege FC, Hazewinkel HA, Creemers LB, Penning LC, Tryfonidou MA.

Arthritis Res Ther. 2013 Jan 29;15(1):R23. doi: 10.1186/ar4157.

29.

Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.

Hoekstra EJ, von Oerthel L, van der Linden AJ, Schellevis RD, Scheppink G, Holstege FC, Groot-Koerkamp MJ, van der Heide LP, Smidt MP.

Eur J Neurosci. 2013 Jan;37(1):23-32. doi: 10.1111/ejn.12022. Epub 2012 Oct 29.

PMID:
23106268
30.

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy.

van der Vos KE, Eliasson P, Proikas-Cezanne T, Vervoort SJ, van Boxtel R, Putker M, van Zutphen IJ, Mauthe M, Zellmer S, Pals C, Verhagen LP, Groot Koerkamp MJ, Braat AK, Dansen TB, Holstege FC, Gebhardt R, Burgering BM, Coffer PJ.

Nat Cell Biol. 2012 Aug;14(8):829-37. doi: 10.1038/ncb2536. Epub 2012 Jul 22.

PMID:
22820375
31.

Amygdala 14-3-3ζ as a novel modulator of escalating alcohol intake in mice.

Lesscher HM, Houthuijzen JM, Groot Koerkamp MJ, Holstege FC, Vanderschuren LJ.

PLoS One. 2012;7(5):e37999. doi: 10.1371/journal.pone.0037999. Epub 2012 May 22.

32.

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression.

Westendorp B, Mokry M, Groot Koerkamp MJ, Holstege FC, Cuppen E, de Bruin A.

Nucleic Acids Res. 2012 Apr;40(8):3511-23. doi: 10.1093/nar/gkr1203. Epub 2011 Dec 17.

33.

Caenorhabditis elegans cyclin D/CDK4 and cyclin E/CDK2 induce distinct cell cycle re-entry programs in differentiated muscle cells.

Korzelius J, The I, Ruijtenberg S, Prinsen MB, Portegijs V, Middelkoop TC, Groot Koerkamp MJ, Holstege FC, Boxem M, van den Heuvel S.

PLoS Genet. 2011 Nov;7(11):e1002362. doi: 10.1371/journal.pgen.1002362. Epub 2011 Nov 10.

34.

The specificity and topology of chromatin interaction pathways in yeast.

Lenstra TL, Benschop JJ, Kim T, Schulze JM, Brabers NA, Margaritis T, van de Pasch LA, van Heesch SA, Brok MO, Groot Koerkamp MJ, Ko CW, van Leenen D, Sameith K, van Hooff SR, Lijnzaad P, Kemmeren P, Hentrich T, Kobor MS, Buratowski S, Holstege FC.

Mol Cell. 2011 May 20;42(4):536-49. doi: 10.1016/j.molcel.2011.03.026.

35.

Functional overlap and regulatory links shape genetic interactions between signaling pathways.

van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC.

Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021.

36.

Tight control of MEK-ERK activation is essential in regulating proliferation, survival, and cytokine production of CD34+-derived neutrophil progenitors.

Geest CR, Buitenhuis M, Groot Koerkamp MJ, Holstege FC, Vellenga E, Coffer PJ.

Blood. 2009 Oct 15;114(16):3402-12. doi: 10.1182/blood-2008-08-175141. Epub 2009 Aug 10.

37.

Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo.

Raaben M, Groot Koerkamp MJ, Rottier PJ, de Haan CA.

BMC Genomics. 2009 Aug 3;10:350. doi: 10.1186/1471-2164-10-350.

38.

Differential gene-expression and host-response profiles against avian influenza virus within the chicken lung due to anatomy and airflow.

Reemers SS, van Haarlem DA, Groot Koerkamp MJ, Vervelde L.

J Gen Virol. 2009 Sep;90(Pt 9):2134-46. doi: 10.1099/vir.0.012401-0. Epub 2009 Jun 3.

PMID:
19494054
39.

Cellular host transcriptional responses to influenza A virus in chicken tracheal organ cultures differ from responses in in vivo infected trachea.

Reemers SS, Groot Koerkamp MJ, Holstege FC, van Eden W, Vervelde L.

Vet Immunol Immunopathol. 2009 Dec 15;132(2-4):91-100. doi: 10.1016/j.vetimm.2009.04.021. Epub 2009 May 4.

PMID:
19447504
40.

High-resolution genetic mapping of mammalian motor activity levels in mice.

Kas MJ, de Mooij-van Malsen JG, de Krom M, van Gassen KL, van Lith HA, Olivier B, Oppelaar H, Hendriks J, de Wit M, Groot Koerkamp MJ, Holstege FC, van Oost BA, de Graan PN.

Genes Brain Behav. 2009 Feb;8(1):13-22. doi: 10.1111/j.1601-183X.2008.00435.x. Epub 2008 Aug 21.

41.

cDNA microarray profiles of canine mammary tumour cell lines reveal deregulated pathways pertaining to their phenotype.

Rao NA, van Wolferen ME, van den Ham R, van Leenen D, Groot Koerkamp MJ, Holstege FC, Mol JA.

Anim Genet. 2008 Aug;39(4):333-45. doi: 10.1111/j.1365-2052.2008.01733.x. Epub 2008 May 6.

PMID:
18462483
42.

Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies.

Raaben M, Groot Koerkamp MJ, Rottier PJ, de Haan CA.

Cell Microbiol. 2007 Sep;9(9):2218-29. Epub 2007 May 8.

PMID:
17490409
43.

Maintenance of head and neck tumor gene expression profiles upon lymph node metastasis.

Roepman P, de Jager A, Groot Koerkamp MJ, Kummer JA, Slootweg PJ, Holstege FC.

Cancer Res. 2006 Dec 1;66(23):11110-4.

44.

Genetic profiling of aortic allografts: prothymosin alpha as potential target?

Joosten SA, Smit van Dixhoorn MG, Borrias MC, Ham V, Groot Koerkamp MJ, Savolainen-Peltonen HM, Häyry P, Daha MR, Kooten C, Paul LC.

Transpl Int. 2005 Aug;18(8):1010-5.

45.

Changes in mRNA expression profile underlie phenotypic adaptations in creatine kinase-deficient muscles.

de Groof AJ, Smeets B, Groot Koerkamp MJ, Mul AN, Janssen EE, Tabak HF, Wieringa B.

FEBS Lett. 2001 Sep 28;506(1):73-8. Erratum in: FEBS Lett 2001 Nov 9;508(1):163.

46.

Interlocked circle formation by group I introns: structural requirements and mechanism.

Winter AJ, Alkema MJ, Groot Koerkamp MJ, van der Horst G, Mul Y, Tabak HF.

Nucleic Acids Res. 1993 Jul 11;21(14):3217-26.

47.

Splice site selection by intron aI3 of the COX1 gene from Saccharomyces cerevisiae.

Winter AJ, Groot Koerkamp MJ, Tabak HF.

Nucleic Acids Res. 1992 Aug 11;20(15):3897-904.

48.

The mechanism of group I self-splicing: an internal guide sequence can be provided in trans.

Winter AJ, Groot Koerkamp MJ, Tabak HF.

EMBO J. 1990 Jun;9(6):1923-8.

49.

RNA polymerase induces DNA bending at yeast mitochondrial promoters.

Schinkel AH, Groot Koerkamp MJ, Teunissen AW, Tabak HF.

Nucleic Acids Res. 1988 Oct 11;16(19):9147-63.

50.

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