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Secondary Syphilis Without Any History of Primary Infection.

Grade M, Bronnert J.

Dtsch Arztebl Int. 2018 Jan 19;115(3):40. doi: 10.3238/arztebl.2018.0040. No abstract available.


Colorectal cancer susceptibility loci as predictive markers of rectal cancer prognosis after surgery.

Hu Y, Gaedcke J, Emons G, Beissbarth T, Grade M, Jo P, Yeager M, Chanock SJ, Wolff H, Camps J, Ghadimi BM, Ried T.

Genes Chromosomes Cancer. 2018 Mar;57(3):140-149. doi: 10.1002/gcc.22512. Epub 2017 Nov 28.


A case report of delayed intra-abdominal and intra-luminal haemorrhage after polypectomy.

Neesse A, Grade M, Dango S, Ghadimi M, Ellenrieder V, Kunsch S, Amanzada A.

Z Gastroenterol. 2017 Oct;55(10):1009-1013. doi: 10.1055/s-0043-108125. Epub 2017 Oct 11.


Posttraumatic Aneurysm of a Patent Umbilical Vein: Diagnosis and Specific Treatment.

Grade M, Krishnabhakdi S, Vestring T, Löbermann M, Arnold JC.

Surg J (N Y). 2017 Jul 19;3(3):e113-e116. doi: 10.1055/s-0037-1604075. eCollection 2017 Jul.


Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.

Emons G, Spitzner M, Reineke S, Möller J, Auslander N, Kramer F, Hu Y, Beissbarth T, Wolff HA, Rave-Fränk M, Heßmann E, Gaedcke J, Ghadimi BM, Johnsen SA, Ried T, Grade M.

Mol Cancer Res. 2017 Nov;15(11):1481-1490. doi: 10.1158/1541-7786.MCR-17-0205. Epub 2017 Aug 15.


Changes of Microrna Levels in Plasma of Patients with Rectal Cancer during Chemoradiotherapy.

Jo P, Azizian A, Salendo J, Kramer F, Bernhardt M, Wolff HA, Gruber J, Grade M, Beißbarth T, Ghadimi BM, Gaedcke J.

Int J Mol Sci. 2017 May 27;18(6). pii: E1140. doi: 10.3390/ijms18061140.


Surgical volunteerism or voluntourism - Are we doing more harm than good?

Ahmed F, Grade M, Malm C, Michelen S, Ahmed N.

Int J Surg. 2017 Jun;42:69-71. doi: 10.1016/j.ijsu.2017.04.020. Epub 2017 Apr 19.


Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.

Chen NM, Neesse A, Dyck ML, Steuber B, Koenig AO, Lubeseder-Martellato C, Winter T, Forster T, Bohnenberger H, Kitz J, Reuter-Jessen K, Griesmann H, Gaedcke J, Grade M, Zhang JS, Tsai WC, Siveke J, Schildhaus HU, Ströbel P, Johnsen SA, Ellenrieder V, Hessmann E.

Gastroenterology. 2017 May;152(6):1507-1520.e15. doi: 10.1053/j.gastro.2017.01.043. Epub 2017 Feb 8.


Cost-effectiveness of Stereotactic Body Radiation Therapy versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Markov Modeling Study.

Pollom EL, Lee K, Durkee BY, Grade M, Mokhtari DA, Wahl DR, Feng M, Kothary N, Koong AC, Owens DK, Goldhaber-Fiebert J, Chang DT.

Radiology. 2017 May;283(2):460-468. doi: 10.1148/radiol.2016161509. Epub 2017 Jan 3.


Loss of CHD1 causes DNA repair defects and enhances prostate cancer therapeutic responsiveness.

Kari V, Mansour WY, Raul SK, Baumgart SJ, Mund A, Grade M, Sirma H, Simon R, Will H, Dobbelstein M, Dikomey E, Johnsen SA.

EMBO Rep. 2016 Nov;17(11):1609-1623. Epub 2016 Sep 5.


[Intraoperative multidimensional visualization].

Sperling J, Kauffels A, Grade M, Alves F, Kühn P, Ghadimi BM.

Chirurg. 2016 Dec;87(12):1015-1024. German.


Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies.

Jo P, Nietert M, Gusky L, Kitz J, Conradi LC, Müller-Dornieden A, Schüler P, Wolff HA, Rüschoff J, Ströbel P, Grade M, Liersch T, Beißbarth T, Ghadimi MB, Sax U, Gaedcke J.

Sci Rep. 2016 Oct 18;6:35589. doi: 10.1038/srep35589.


Histone Chaperone SSRP1 is Essential for Wnt Signaling Pathway Activity During Osteoblast Differentiation.

Hossan T, Nagarajan S, Baumgart SJ, Xie W, Magallanes RT, Hernandez C, Chiaroni PM, Indenbirken D, Spitzner M, Thomas-Chollier M, Grade M, Thieffry D, Grundhoff A, Wegwitz F, Johnsen SA.

Stem Cells. 2016 May;34(5):1369-76. doi: 10.1002/stem.2287. Epub 2016 Feb 13.


Prognostic Value of MicroRNAs in Preoperative Treated Rectal Cancer.

Azizian A, Epping I, Kramer F, Jo P, Bernhardt M, Kitz J, Salinas G, Wolff HA, Grade M, Beißbarth T, Ghadimi BM, Gaedcke J.

Int J Mol Sci. 2016 Apr 15;17(4):568. doi: 10.3390/ijms17040568.


[Robotic Rectal Cancer Surgery].

Grade M, Ridwelski K, Voigt I, Ghadimi BM, Mann B.

Zentralbl Chir. 2016 Apr;141(2):165-9. doi: 10.1055/s-0042-101960. Epub 2016 Apr 13. German.


Heterogeneity of KRAS Mutation Status in Rectal Cancer.

Jo P, König A, Schirmer M, Kitz J, Conradi LC, Azizian A, Bernhardt M, Wolff HA, Grade M, Ghadimi M, Ströbel P, Schildhaus HU, Gaedcke J.

PLoS One. 2016 Apr 11;11(4):e0153278. doi: 10.1371/journal.pone.0153278. eCollection 2016.


Pelvic intraoperative neuromonitoring during robotic-assisted low anterior resection for rectal cancer.

Grade M, Beham AW, Schüler P, Kneist W, Ghadimi BM.

J Robot Surg. 2016 Jun;10(2):157-60. doi: 10.1007/s11701-015-0556-6. Epub 2015 Dec 24.


Patterns of Chromosomal Aberrations in Solid Tumors.

Grade M, Difilippantonio MJ, Camps J.

Recent Results Cancer Res. 2015;200:115-42. doi: 10.1007/978-3-319-20291-4_6. Review.


A neuroradiologist's guide to arterial spin labeling MRI in clinical practice.

Grade M, Hernandez Tamames JA, Pizzini FB, Achten E, Golay X, Smits M.

Neuroradiology. 2015 Dec;57(12):1181-202. doi: 10.1007/s00234-015-1571-z. Epub 2015 Sep 9. Review.


Preoperative Prediction of Lymph Node Status by Circulating Mir-18b and Mir-20a During Chemoradiotherapy in Patients with Rectal Cancer.

Azizian A, Kramer F, Jo P, Wolff HA, Beißbarth T, Skarupke R, Bernhardt M, Grade M, Ghadimi BM, Gaedcke J.

World J Surg. 2015 Sep;39(9):2329-35. doi: 10.1007/s00268-015-3083-8.


Preliminary results of the global audit of treatment of refractory status epilepticus.

Ferlisi M, Hocker S, Grade M, Trinka E, Shorvon S; International Steering Committee of the StEp Audit.

Epilepsy Behav. 2015 Aug;49:318-24. doi: 10.1016/j.yebeh.2015.04.010. Epub 2015 May 4. Erratum in: Epilepsy Behav. 2015 Nov;52(Pt A):132. Zeid, Yasiri [corrected to Yasiry, Zeid].


STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy.

Spitzner M, Ebner R, Wolff HA, Ghadimi BM, Wienands J, Grade M.

Cancers (Basel). 2014 Sep 29;6(4):1986-2011. doi: 10.3390/cancers6041986. Review.


Identification of a DNA methylation signature to predict disease-free survival in locally advanced rectal cancer.

Gaedcke J, Leha A, Claus R, Weichenhan D, Jung K, Kitz J, Grade M, Wolff HA, Jo P, Doyen J, Gérard JP, Johnsen SA, Plass C, Beißbarth T, Ghadimi M.

Oncotarget. 2014 Sep 30;5(18):8123-35.


UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib.

Landmann H, Proia DA, He S, Ogawa LS, Kramer F, Beißbarth T, Grade M, Gaedcke J, Ghadimi M, Moll U, Dobbelstein M.

Cell Death Dis. 2014 Sep 11;5:e1411. doi: 10.1038/cddis.2014.378.


STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo.

Spitzner M, Roesler B, Bielfeld C, Emons G, Gaedcke J, Wolff HA, Rave-Fränk M, Kramer F, Beissbarth T, Kitz J, Wienands J, Ghadimi BM, Ebner R, Ried T, Grade M.

Int J Cancer. 2014 Feb 15;134(4):997-1007. doi: 10.1002/ijc.28429. Epub 2013 Sep 3.


Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.

Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, Kitz J, Kaulfuß S, Beißbarth T, Dobbelstein M, Ghadimi M, Grade M, Gaedcke J.

Radiother Oncol. 2013 Sep;108(3):451-7. doi: 10.1016/j.radonc.2013.06.032. Epub 2013 Aug 7.


[General principles of tumour biology in visceral surgery].

Emons G, Ghadimi M, Grade M.

Zentralbl Chir. 2015 Feb;140(1):74-82. doi: 10.1055/s-0032-1328590. Epub 2013 Aug 5. Review. German.


[Value of one-stage surgical treatment of diffuse peritonitis (relaparotomy on demand): a single-center analysis].

Pauly S, Schulze FP, Horstmann O, Becker H, Grade M, Ghadimi M.

Zentralbl Chir. 2013 Jun;138(3):289-94. doi: 10.1055/s-0032-1328006. Epub 2013 Apr 10. German.


Increasing toxicity during neoadjuvant radiochemotherapy as positive prognostic factor for patients with esophageal carcinoma.

Hennies S, Hermann RM, Gaedcke J, Grade M, Hess CF, Christiansen H, Wolff HA.

Dis Esophagus. 2014 Feb-Mar;27(2):146-51. doi: 10.1111/dote.12067. Epub 2013 Apr 9.


Genetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.

Camps J, Pitt JJ, Emons G, Hummon AB, Case CM, Grade M, Jones TL, Nguyen QT, Ghadimi BM, Beissbarth T, Difilippantonio MJ, Caplen NJ, Ried T.

Cancer Res. 2013 Mar 15;73(6):2003-13. doi: 10.1158/0008-5472.CAN-12-3159. Epub 2013 Jan 14.


Rapid re-expression of CD133 protein in colorectal cancer cell lines in vitro and in vivo.

Peickert S, Waurig J, Dittfeld C, Dietrich A, Garbe Y, Kabus L, Baumann M, Grade M, Ried T, Kunz-Schughart LA.

Lab Invest. 2012 Nov;92(11):1607-22. doi: 10.1038/labinvest.2012.124. Epub 2012 Sep 10.


The rectal cancer microRNAome--microRNA expression in rectal cancer and matched normal mucosa.

Gaedcke J, Grade M, Camps J, Søkilde R, Kaczkowski B, Schetter AJ, Difilippantonio MJ, Harris CC, Ghadimi BM, Møller S, Beissbarth T, Ried T, Litman T.

Clin Cancer Res. 2012 Sep 15;18(18):4919-30. Epub 2012 Jul 31.


The consequences of chromosomal aneuploidy on the transcriptome of cancer cells.

Ried T, Hu Y, Difilippantonio MJ, Ghadimi BM, Grade M, Camps J.

Biochim Biophys Acta. 2012 Jul;1819(7):784-93. doi: 10.1016/j.bbagrm.2012.02.020. Epub 2012 Mar 6. Review.


The molecular basis of chemoradiosensitivity in rectal cancer: implications for personalized therapies.

Grade M, Wolff HA, Gaedcke J, Ghadimi BM.

Langenbecks Arch Surg. 2012 Apr;397(4):543-55. doi: 10.1007/s00423-012-0929-5. Epub 2012 Mar 2. Review.


Confirming psychogenic nonepileptic seizures with video-EEG: sex matters.

Noe KH, Grade M, Stonnington CM, Driver-Dunckley E, Locke DE.

Epilepsy Behav. 2012 Mar;23(3):220-3. doi: 10.1016/j.yebeh.2011.12.015. Epub 2012 Feb 15.


Systems-wide RNAi analysis of CASP8AP2/FLASH shows transcriptional deregulation of the replication-dependent histone genes and extensive effects on the transcriptome of colorectal cancer cells.

Hummon AB, Pitt JJ, Camps J, Emons G, Skube SB, Huppi K, Jones TL, Beissbarth T, Kramer F, Grade M, Difilippantonio MJ, Ried T, Caplen NJ.

Mol Cancer. 2012 Jan 4;11:1. doi: 10.1186/1476-4598-11-1.


CpG island methylator phenotype infers a poor disease-free survival in locally advanced rectal cancer.

Jo P, Jung K, Grade M, Conradi LC, Wolff HA, Kitz J, Becker H, Rüschoff J, Hartmann A, Beissbarth T, Müller-Dornieden A, Ghadimi M, Schneider-Stock R, Gaedcke J.

Surgery. 2012 Apr;151(4):564-70. doi: 10.1016/j.surg.2011.08.013. Epub 2011 Oct 14.


Silencing of the Wnt transcription factor TCF4 sensitizes colorectal cancer cells to (chemo-) radiotherapy.

Kendziorra E, Ahlborn K, Spitzner M, Rave-Fränk M, Emons G, Gaedcke J, Kramer F, Wolff HA, Becker H, Beissbarth T, Ebner R, Ghadimi BM, Pukrop T, Ried T, Grade M.

Carcinogenesis. 2011 Dec;32(12):1824-31. doi: 10.1093/carcin/bgr222. Epub 2011 Oct 8.


Retraction for Garman et al: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities.

Garman KS, Acharya CR, Edelman E, Grade M, Gaedcke J, Sud S, Barry W, Diehl AM, Provenzale D, Ginsburg GS, Ghadimi BM, Ried T, Nevins JR, Mukherjee S, Hsu D, Potti A.

Proc Natl Acad Sci U S A. 2011 Oct 18;108(42):17569. doi: 10.1073/pnas.1115170108. Epub 2011 Oct 3. No abstract available.


Standard perioperative management in gastrointestinal surgery.

Grade M, Quintel M, Ghadimi BM.

Langenbecks Arch Surg. 2011 Jun;396(5):591-606. doi: 10.1007/s00423-011-0782-y. Epub 2011 Mar 30. Review.


Indeterminate EMU admissions: does repeating the admission help?

Zarkou S, Grade M, Hoerth MT, Noe KH, Sirven JI, Drazkowski JF.

Epilepsy Behav. 2011 Apr;20(4):706-8. doi: 10.1016/j.yebeh.2011.01.032. Epub 2011 Mar 26.


A gene expression signature for chemoradiosensitivity of colorectal cancer cells.

Spitzner M, Emons G, Kramer F, Gaedcke J, Rave-Fränk M, Scharf JG, Burfeind P, Becker H, Beissbarth T, Ghadimi BM, Ried T, Grade M.

Int J Radiat Oncol Biol Phys. 2010 Nov 15;78(4):1184-92. doi: 10.1016/j.ijrobp.2010.06.023.


Mutated KRAS results in overexpression of DUSP4, a MAP-kinase phosphatase, and SMYD3, a histone methyltransferase, in rectal carcinomas.

Gaedcke J, Grade M, Jung K, Camps J, Jo P, Emons G, Gehoff A, Sax U, Schirmer M, Becker H, Beissbarth T, Ried T, Ghadimi BM.

Genes Chromosomes Cancer. 2010 Nov;49(11):1024-34. doi: 10.1002/gcc.20811.


Impact of RNA degradation on gene expression profiling.

Opitz L, Salinas-Riester G, Grade M, Jung K, Jo P, Emons G, Ghadimi BM, Beissbarth T, Gaedcke J.

BMC Med Genomics. 2010 Aug 9;3:36. doi: 10.1186/1755-8794-3-36.


A genomic strategy for the functional validation of colorectal cancer genes identifies potential therapeutic targets.

Grade M, Hummon AB, Camps J, Emons G, Spitzner M, Gaedcke J, Hoermann P, Ebner R, Becker H, Difilippantonio MJ, Ghadimi BM, Beissbarth T, Caplen NJ, Ried T.

Int J Cancer. 2011 Mar 1;128(5):1069-79. doi: 10.1002/ijc.25453.


A new sensitivity-preferred strategy to build prediction rules for therapy response of cancer patients using gene expression data.

Jung K, Grade M, Gaedcke J, Jo P, Opitz L, Becker H, Ghadimi BM, Beissbarth T.

Comput Methods Programs Biomed. 2010 Nov;100(2):132-9. doi: 10.1016/j.cmpb.2010.03.016. Epub 2010 Apr 10.


CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell line HCT-116.

Dittfeld C, Dietrich A, Peickert S, Hering S, Baumann M, Grade M, Ried T, Kunz-Schughart LA.

Radiother Oncol. 2010 Mar;94(3):375-83.


KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy.

Gaedcke J, Grade M, Jung K, Schirmer M, Jo P, Obermeyer C, Wolff HA, Herrmann MK, Beissbarth T, Becker H, Ried T, Ghadimi M.

Radiother Oncol. 2010 Jan;94(1):76-81. doi: 10.1016/j.radonc.2009.10.001. Epub 2009 Nov 11.


Cancer gene profiling for response prediction.

Ghadimi BM, Grade M.

Methods Mol Biol. 2010;576:327-39. doi: 10.1007/978-1-59745-545-9_16.


CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell lines HCT-116.

Dittfeld C, Dietrich A, Peickert S, Hering S, Baumann M, Grade M, Ried T, Kunz-Schughart LA.

Radiother Oncol. 2009 Sep;92(3):353-61. doi: 10.1016/j.radonc.2009.06.034. Epub 2009 Aug 21.


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