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Items: 28

1.

Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.

Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T.

Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30.

2.

miR-125b controls monocyte adaptation to inflammation through mitochondrial metabolism and dynamics.

Duroux-Richard I, Roubert C, Ammari M, Présumey J, Grün JR, Häupl T, Grützkau A, Lecellier CH, Boitez V, Codogno P, Escoubet J, Pers YM, Jorgensen C, Apparailly F.

Blood. 2016 Dec 29;128(26):3125-3136. doi: 10.1182/blood-2016-02-697003. Epub 2016 Oct 4.

3.

Differential Expression of miR-4520a Associated With Pyrin Mutations in Familial Mediterranean Fever (FMF).

Latsoudis H, Mashreghi MF, Grün JR, Chang HD, Stuhlmüller B, Repa A, Gergiannaki I, Kabouraki E, Vlachos GS, Häupl T, Radbruch A, Sidiropoulos P, Doukoumetzidis K, Kardassis D, Niewold TB, Boumpas DT, Goulielmos GN.

J Cell Physiol. 2017 Jun;232(6):1326-1336. doi: 10.1002/jcp.25602. Epub 2016 Dec 20.

PMID:
27636101
4.

T-bet expression by Th cells promotes type 1 inflammation but is dispensable for colitis.

Zimmermann J, Kühl AA, Weber M, Grün JR, Löffler J, Haftmann C, Riedel R, Maschmeyer P, Lehmann K, Westendorf K, Mashreghi MF, Löhning M, Mack M, Radbruch A, Chang HD.

Mucosal Immunol. 2016 Nov;9(6):1487-1499. doi: 10.1038/mi.2016.5. Epub 2016 Feb 17.

PMID:
26883725
5.

Identification of T Cell-Mediated Vascular Rejection After Kidney Transplantation by the Combined Measurement of 5 Specific MicroRNAs in Blood.

Matz M, Fabritius K, Lorkowski C, Dürr M, Gaedeke J, Durek P, Grün JR, Goestemeyer A, Bachmann F, Wu K, Rudolph B, Schmidt D, Weber U, Haftmann C, Unterwalder N, Lachmann N, Radbruch A, Neumayer HH, Mashreghi MF, Budde K.

Transplantation. 2016 Apr;100(4):898-907. doi: 10.1097/TP.0000000000000873.

PMID:
26444957
6.

De novo-induced self-antigen-specific Foxp3+ regulatory T cells impair the accumulation of inflammatory dendritic cells in draining lymph nodes.

Alissafi T, Hatzioannou A, Ioannou M, Sparwasser T, Grün JR, Grützkau A, Verginis P.

J Immunol. 2015 Jun 15;194(12):5812-24. doi: 10.4049/jimmunol.1500111. Epub 2015 May 6.

7.

ICOS maintains the T follicular helper cell phenotype by down-regulating Krüppel-like factor 2.

Weber JP, Fuhrmann F, Feist RK, Lahmann A, Al Baz MS, Gentz LJ, Vu Van D, Mages HW, Haftmann C, Riedel R, Grün JR, Schuh W, Kroczek RA, Radbruch A, Mashreghi MF, Hutloff A.

J Exp Med. 2015 Feb 9;212(2):217-33. doi: 10.1084/jem.20141432. Epub 2015 Feb 2.

8.

Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription.

Sercan Alp Ö, Durlanik S, Schulz D, McGrath M, Grün JR, Bardua M, Ikuta K, Sgouroudis E, Riedel R, Zehentmeier S, Hauser AE, Tsuneto M, Melchers F, Tokoyoda K, Chang HD, Thiel A, Radbruch A.

Eur J Immunol. 2015 Apr;45(4):975-87. doi: 10.1002/eji.201445295. Epub 2015 Feb 27.

9.

A unique population of IgG-expressing plasma cells lacking CD19 is enriched in human bone marrow.

Mei HE, Wirries I, Frölich D, Brisslert M, Giesecke C, Grün JR, Alexander T, Schmidt S, Luda K, Kühl AA, Engelmann R, Dürr M, Scheel T, Bokarewa M, Perka C, Radbruch A, Dörner T.

Blood. 2015 Mar 12;125(11):1739-48. doi: 10.1182/blood-2014-02-555169. Epub 2015 Jan 8.

10.

miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF.

Eur J Immunol. 2015 Apr;45(4):1192-205. doi: 10.1002/eji.201444633. Epub 2015 Jan 22.

11.

Rsk2 controls synovial fibroblast hyperplasia and the course of arthritis.

Derer A, Böhm C, Grötsch B, Grün JR, Grützkau A, Stock M, Böhm S, Sehnert B, Gaipl U, Schett G, Hueber AJ, David JP.

Ann Rheum Dis. 2016 Feb;75(2):413-21. doi: 10.1136/annrheumdis-2014-205618. Epub 2014 Nov 20.

PMID:
25414238
12.

Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory.

Okhrimenko A, Grün JR, Westendorf K, Fang Z, Reinke S, von Roth P, Wassilew G, Kühl AA, Kudernatsch R, Demski S, Scheibenbogen C, Tokoyoda K, McGrath MA, Raftery MJ, Schönrich G, Serra A, Chang HD, Radbruch A, Dong J.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9229-34. doi: 10.1073/pnas.1318731111. Epub 2014 Jun 10.

13.

Reprint of: Environments of B cell development.

Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, Grützkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K, Melchers F.

Immunol Lett. 2014 Aug;160(2):109-12. doi: 10.1016/j.imlet.2014.05.005. Epub 2014 May 20.

PMID:
24852107
14.

Autocrine IL-10 promotes human B-cell differentiation into IgM- or IgG-secreting plasmablasts.

Heine G, Drozdenko G, Grün JR, Chang HD, Radbruch A, Worm M.

Eur J Immunol. 2014 Jun;44(6):1615-21. doi: 10.1002/eji.201343822. Epub 2014 Mar 11.

15.

Unbiased transcriptomes of resting human CD4⁺ CD45RO⁺ T lymphocytes.

Westendorf K, Okhrimenko A, Grün JR, Schliemann H, Chang HD, Dong J, Radbruch A.

Eur J Immunol. 2014 Jun;44(6):1866-9. doi: 10.1002/eji.201344323. Epub 2014 Apr 16. No abstract available.

16.

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases.

Shen P, Roch T, Lampropoulou V, O'Connor RA, Stervbo U, Hilgenberg E, Ries S, Dang VD, Jaimes Y, Daridon C, Li R, Jouneau L, Boudinot P, Wilantri S, Sakwa I, Miyazaki Y, Leech MD, McPherson RC, Wirtz S, Neurath M, Hoehlig K, Meinl E, Grützkau A, Grün JR, Horn K, Kühl AA, Dörner T, Bar-Or A, Kaufmann SHE, Anderton SM, Fillatreau S.

Nature. 2014 Mar 20;507(7492):366-370. doi: 10.1038/nature12979. Epub 2014 Feb 23.

17.

Influence of CD8 T cell priming in liver and gut on the enterohepatic circulation.

Eickmeier I, Seidel D, Grün JR, Derkow K, Lehnardt S, Kühl AA, Hamann A, Schott E.

J Hepatol. 2014 Jun;60(6):1143-50. doi: 10.1016/j.jhep.2014.02.011. Epub 2014 Feb 19.

PMID:
24560659
18.

Cell-specific type I IFN signatures in autoimmunity and viral infection: what makes the difference?

Kyogoku C, Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Häupl T, Hiepe F, Alexander T, Radbruch A, Grützkau A.

PLoS One. 2013 Dec 31;8(12):e83776. doi: 10.1371/journal.pone.0083776. eCollection 2013.

19.

Environments of B cell development.

Tsuneto M, Kajikhina E, Seiler K, Reimer A, Tornack J, Bouquet C, Simmons S, Knoll M, Wolf I, Tokoyoda K, Hauser A, Hara T, Tani-ichi S, Ikuta K, Grün JR, Grützkau A, Engels N, Wienands J, Yanagisawa Y, Ohnishi K, Melchers F.

Immunol Lett. 2014 Jan-Feb;157(1-2):60-3. doi: 10.1016/j.imlet.2013.11.011. Epub 2013 Nov 24. Review.

PMID:
24284375
20.

Ectopic Runx1 expression rescues Tal-1-deficiency in the generation of primitive and definitive hematopoiesis.

Tornack J, Seiler K, Grützkau A, Grün JR, Onodera M, Melchers F, Tsuneto M.

PLoS One. 2013 Jul 29;8(7):e70116. doi: 10.1371/journal.pone.0070116. Print 2013.

21.

miR-221 redirects precursor B cells to the BM and regulates their residence.

Knoll M, Simmons S, Bouquet C, Grün JR, Melchers F.

Eur J Immunol. 2013 Sep;43(9):2497-506. doi: 10.1002/eji.201343367. Epub 2013 Jul 8.

22.

The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.

Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A.

J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19.

PMID:
22610275
23.

Defining TNF-α- and LPS-induced gene signatures in monocytes to unravel the complexity of peripheral blood transcriptomes in health and disease.

Smiljanovic B, Grün JR, Steinbrich-Zöllner M, Stuhlmüller B, Häupl T, Burmester GR, Radbruch A, Grützkau A, Baumgrass R.

J Mol Med (Berl). 2010 Oct;88(10):1065-79. doi: 10.1007/s00109-010-0648-8. Epub 2010 Jul 17.

PMID:
20640394
24.

Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow.

Tokoyoda K, Zehentmeier S, Hegazy AN, Albrecht I, Grün JR, Löhning M, Radbruch A.

Immunity. 2009 May;30(5):721-30. doi: 10.1016/j.immuni.2009.03.015. Epub 2009 May 7.

25.

SiPaGene: A new repository for instant online retrieval, sharing and meta-analyses of GeneChip expression data.

Menssen A, Edinger G, Grün JR, Haase U, Baumgrass R, Grützkau A, Radbruch A, Burmester GR, Häupl T.

BMC Genomics. 2009 Mar 5;10:98. doi: 10.1186/1471-2164-10-98.

26.

Sialic acid-binding Ig-like lectin 1 expression in inflammatory and resident monocytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus.

Biesen R, Demir C, Barkhudarova F, Grün JR, Steinbrich-Zöllner M, Backhaus M, Häupl T, Rudwaleit M, Riemekasten G, Radbruch A, Hiepe F, Burmester GR, Grützkau A.

Arthritis Rheum. 2008 Apr;58(4):1136-45. doi: 10.1002/art.23404.

27.

From transcriptome to cytome: integrating cytometric profiling, multivariate cluster, and prediction analyses for a phenotypical classification of inflammatory diseases.

Steinbrich-Zöllner M, Grün JR, Kaiser T, Biesen R, Raba K, Wu P, Thiel A, Rudwaleit M, Sieper J, Burmester GR, Radbruch A, Grützkau A.

Cytometry A. 2008 Apr;73(4):333-40. doi: 10.1002/cyto.a.20505.

28.

CD303 (BDCA-2) signals in plasmacytoid dendritic cells via a BCR-like signalosome involving Syk, Slp65 and PLCgamma2.

Röck J, Schneider E, Grün JR, Grützkau A, Küppers R, Schmitz J, Winkels G.

Eur J Immunol. 2007 Dec;37(12):3564-75.

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