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Items: 7


New class of precision antimicrobials redefines role of Clostridium difficile S-layer in virulence and viability.

Kirk JA, Gebhart D, Buckley AM, Lok S, Scholl D, Douce GR, Govoni GR, Fagan RP.

Sci Transl Med. 2017 Sep 6;9(406). pii: eaah6813. doi: 10.1126/scitranslmed.aah6813.


F-Type Bacteriocins of Listeria monocytogenes: a New Class of Phage Tail-Like Structures Reveals Broad Parallel Coevolution between Tailed Bacteriophages and High-Molecular-Weight Bacteriocins.

Lee G, Chakraborty U, Gebhart D, Govoni GR, Zhou ZH, Scholl D.

J Bacteriol. 2016 Sep 22;198(20):2784-93. doi: 10.1128/JB.00489-16. Print 2016 Oct 15.


A modified R-type bacteriocin specifically targeting Clostridium difficile prevents colonization of mice without affecting gut microbiota diversity.

Gebhart D, Lok S, Clare S, Tomas M, Stares M, Scholl D, Donskey CJ, Lawley TD, Govoni GR.

MBio. 2015 Mar 24;6(2). pii: e02368-14. doi: 10.1128/mBio.02368-14.


Novel high-molecular-weight, R-type bacteriocins of Clostridium difficile.

Gebhart D, Williams SR, Bishop-Lilly KA, Govoni GR, Willner KM, Butani A, Sozhamannan S, Martin D, Fortier LC, Scholl D.

J Bacteriol. 2012 Nov;194(22):6240-7. doi: 10.1128/JB.01272-12. Epub 2012 Sep 14.


Two physically, functionally, and developmentally distinct peritoneal macrophage subsets.

Ghosn EE, Cassado AA, Govoni GR, Fukuhara T, Yang Y, Monack DM, Bortoluci KR, Almeida SR, Herzenberg LA, Herzenberg LA.

Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2568-73. doi: 10.1073/pnas.0915000107. Epub 2010 Jan 25.


The Salmonella SPI2 effector SseI mediates long-term systemic infection by modulating host cell migration.

McLaughlin LM, Govoni GR, Gerke C, Gopinath S, Peng K, Laidlaw G, Chien YH, Jeong HW, Li Z, Brown MD, Sacks DB, Monack D.

PLoS Pathog. 2009 Nov;5(11):e1000671. doi: 10.1371/journal.ppat.1000671. Epub 2009 Nov 26.


Genome-wide screen for Salmonella genes required for long-term systemic infection of the mouse.

Lawley TD, Chan K, Thompson LJ, Kim CC, Govoni GR, Monack DM.

PLoS Pathog. 2006 Feb;2(2):e11. Epub 2006 Feb 24.

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