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Items: 1 to 50 of 137

1.

Anthelmintic efficacy of glycolipid biosurfactant produced by Pseudomonas plecoglossicida: an insight from mutant and transgenic forms of Caenorhabditis elegans.

Devaraj S, Amirthalingam M, Sabapathy PC, Govindan S, Palanisamy S, Kathirvel P.

Biodegradation. 2018 Apr 16. doi: 10.1007/s10532-018-9831-3. [Epub ahead of print]

PMID:
29663166
2.

Phytochemicals-induced hormesis protects Caenorhabditis elegans against α-synuclein protein aggregation and stress through modulating HSF-1 and SKN-1/Nrf2 signaling pathways.

Govindan S, Amirthalingam M, Duraisamy K, Govindhan T, Sundararaj N, Palanisamy S.

Biomed Pharmacother. 2018 Jun;102:812-822. doi: 10.1016/j.biopha.2018.03.128. Epub 2018 Apr 5.

PMID:
29605769
3.

Sample size implications of mortality definitions in sepsis: a retrospective cohort study.

Govindan S, Prescott HC, Chopra V, Iwashyna TJ.

Trials. 2018 Mar 27;19(1):198. doi: 10.1186/s13063-018-2570-2.

4.

Cancer stem cell and its niche in malignant progression of oral potentially malignant disorders.

Surendran S, Siddappa G, Mohan A, Hicks W Jr, Jayaprakash V, Mimikos C, Mahri M, Almarzouki F, Morrell K, Ravi R, Govindan S, Sushma CN, Raghavan N, Birur P, Ilayaraja J, Merzianu M, Reid M, Suresh A, Kuriakose MA.

Oral Oncol. 2017 Dec;75:140-147. doi: 10.1016/j.oraloncology.2017.11.003. Epub 2017 Nov 12.

5.

Do Experts Understand Performance Measures? A Mixed-Methods Study of Infection Preventionists.

Govindan S, Wallace B, Iwashyna TJ, Chopra V.

Infect Control Hosp Epidemiol. 2018 Jan;39(1):71-76. doi: 10.1017/ice.2017.243. Epub 2017 Dec 5.

PMID:
29202884
6.

IMMU-140, a Novel SN-38 Antibody-Drug Conjugate Targeting HLA-DR, Mediates Dual Cytotoxic Effects in Hematologic Cancers and Malignant Melanoma.

Cardillo TM, Govindan SV, Zalath MB, Rossi DL, Wang Y, Chang CH, Goldenberg DM.

Mol Cancer Ther. 2018 Jan;17(1):150-160. doi: 10.1158/1535-7163.MCT-17-0354. Epub 2017 Nov 13.

PMID:
29133623
7.

Selective and Concentrated Accretion of SN-38 with a CEACAM5-Targeting Antibody-Drug Conjugate (ADC), Labetuzumab Govitecan (IMMU-130).

Sharkey RM, Govindan SV, Cardillo TM, Donnell J, Xia J, Rossi EA, Chang CH, Goldenberg DM.

Mol Cancer Ther. 2018 Jan;17(1):196-203. doi: 10.1158/1535-7163.MCT-17-0442. Epub 2017 Oct 27.

PMID:
29079710
8.

Quick Sequential Organ Failure Assessment: Illness Severity Indicator, Clinical Decision Support Tool, or Both?

Govindan S, Prescott HC.

Crit Care Med. 2017 Nov;45(11):1947-1949. doi: 10.1097/CCM.0000000000002662. No abstract available.

PMID:
29028698
9.

Semisynthetic glycoconjugate vaccine candidate against Streptococcus pneumoniae serotype 5.

Lisboa MP, Khan N, Martin C, Xu FF, Reppe K, Geissner A, Govindan S, Witzenrath M, Pereira CL, Seeberger PH.

Proc Natl Acad Sci U S A. 2017 Oct 17;114(42):11063-11068. doi: 10.1073/pnas.1706875114. Epub 2017 Oct 2.

10.

Coupling progenitor and neuronal diversity in the developing neocortex.

Govindan S, Jabaudon D.

FEBS Lett. 2017 Dec;591(24):3960-3977. doi: 10.1002/1873-3468.12846. Epub 2017 Oct 16. Review.

PMID:
28895133
11.

Using Naïve Bayesian Analysis to Determine Imaging Characteristics of KRAS Mutations in Metastatic Colon Cancer.

Pershad Y, Govindan S, Hara AK, Borad MJ, Bekaii-Saab T, Wallace A, Albadawi H, Oklu R.

Diagnostics (Basel). 2017 Sep 2;7(3). pii: E50. doi: 10.3390/diagnostics7030050.

12.

Usefulness of Released Cardiac Myosin Binding Protein-C as a Predictor of Cardiovascular Events.

Tong CW, Dusio GF, Govindan S, Johnson DW, Kidwell DT, De La Rosa LM, Rosas PC, Liu Y, Ebert E, Newell-Rogers MK, Michel JB, Trzeciakowski JP, Sadayappan S.

Am J Cardiol. 2017 Nov 1;120(9):1501-1507. doi: 10.1016/j.amjcard.2017.07.042. Epub 2017 Jul 31.

13.

Economics of Inhaled Oxygen Use as an Acute Therapy for Cluster Headache in the United States of America.

O'Brien M, Ford JH, Aurora SK, Govindan S, Tepper DE, Tepper SJ.

Headache. 2017 Oct;57(9):1416-1427. doi: 10.1111/head.13167. Epub 2017 Aug 26.

PMID:
28842974
14.

"Giant within a giant": a case of typical Kawasaki disease with a giant coronary aneurysm and a large coronary thrombus - a rare case report.

Rajasekharan S, Kalliath S, Govindan SC.

Cardiol Young. 2018 Jan;28(1):147-149. doi: 10.1017/S1047951117001329. Epub 2017 Aug 24.

PMID:
28835313
15.

Phase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.

Dotan E, Cohen SJ, Starodub AN, Lieu CH, Messersmith WA, Simpson PS, Guarino MJ, Marshall JL, Goldberg RM, Hecht JR, Wegener WA, Sharkey RM, Govindan SV, Goldenberg DM, Berlin JD.

J Clin Oncol. 2017 Oct 10;35(29):3338-3346. doi: 10.1200/JCO.2017.73.9011. Epub 2017 Aug 17.

PMID:
28817371
16.

Therapy of Small Cell Lung Cancer (SCLC) with a Topoisomerase-I-inhibiting Antibody-Drug Conjugate (ADC) Targeting Trop-2, Sacituzumab Govitecan.

Gray JE, Heist RS, Starodub AN, Camidge DR, Kio EA, Masters GA, Purcell WT, Guarino MJ, Misleh J, Schneider CJ, Schneider BJ, Ocean A, Johnson T, Gandhi L, Kalinsky K, Scheff R, Messersmith WA, Govindan SV, Maliakal PP, Mudenda B, Wegener WA, Sharkey RM, Goldenberg DM.

Clin Cancer Res. 2017 Oct 1;23(19):5711-5719. doi: 10.1158/1078-0432.CCR-17-0933. Epub 2017 Jul 5.

PMID:
28679770
17.

Simultaneous adsorption of Remazol brilliant blue and Disperse orange dyes on red mud and isotherms for the mixed dye system.

Gadigayya Mavinkattimath R, Shetty Kodialbail V, Govindan S.

Environ Sci Pollut Res Int. 2017 Aug;24(23):18912-18925. doi: 10.1007/s11356-017-9278-9. Epub 2017 Jun 27.

PMID:
28656570
18.

Sacituzumab govitecan (IMMU-132), an anti-Trop-2-SN-38 antibody-drug conjugate for the treatment of diverse epithelial cancers: Safety and pharmacokinetics.

Ocean AJ, Starodub AN, Bardia A, Vahdat LT, Isakoff SJ, Guarino M, Messersmith WA, Picozzi VJ, Mayer IA, Wegener WA, Maliakal P, Govindan SV, Sharkey RM, Goldenberg DM.

Cancer. 2017 Oct 1;123(19):3843-3854. doi: 10.1002/cncr.30789. Epub 2017 May 30.

PMID:
28558150
19.

Therapy of Advanced Non-Small-Cell Lung Cancer With an SN-38-Anti-Trop-2 Drug Conjugate, Sacituzumab Govitecan.

Heist RS, Guarino MJ, Masters G, Purcell WT, Starodub AN, Horn L, Scheff RJ, Bardia A, Messersmith WA, Berlin J, Ocean AJ, Govindan SV, Maliakal P, Mudenda B, Wegener WA, Sharkey RM, Goldenberg DM, Camidge DR.

J Clin Oncol. 2017 Aug 20;35(24):2790-2797. doi: 10.1200/JCO.2016.72.1894. Epub 2017 May 26.

PMID:
28548889
20.

Identifying Barriers to Delivering the Awakening and Breathing Coordination, Delirium, and Early Exercise/Mobility Bundle to Minimize Adverse Outcomes for Mechanically Ventilated Patients: A Systematic Review.

Costa DK, White MR, Ginier E, Manojlovich M, Govindan S, Iwashyna TJ, Sales AE.

Chest. 2017 Aug;152(2):304-311. doi: 10.1016/j.chest.2017.03.054. Epub 2017 Apr 21. Review.

PMID:
28438605
21.

Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.

Bardia A, Mayer IA, Diamond JR, Moroose RL, Isakoff SJ, Starodub AN, Shah NC, O'Shaughnessy J, Kalinsky K, Guarino M, Abramson V, Juric D, Tolaney SM, Berlin J, Messersmith WA, Ocean AJ, Wegener WA, Maliakal P, Sharkey RM, Govindan SV, Goldenberg DM, Vahdat LT.

J Clin Oncol. 2017 Jul 1;35(19):2141-2148. doi: 10.1200/JCO.2016.70.8297. Epub 2017 Mar 14.

22.

A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

Schumann B, Hahm HS, Parameswarappa SG, Reppe K, Wahlbrink A, Govindan S, Kaplonek P, Pirofski LA, Witzenrath M, Anish C, Pereira CL, Seeberger PH.

Sci Transl Med. 2017 Mar 8;9(380). pii: eaaf5347. doi: 10.1126/scitranslmed.aaf5347.

23.

Total synthesis of a Streptococcus pneumoniae serotype 12F CPS repeating unit hexasaccharide.

Seeberger PH, Pereira CL, Govindan S.

Beilstein J Org Chem. 2017 Jan 25;13:164-173. doi: 10.3762/bjoc.13.19. eCollection 2017.

24.

Do Clinicians Understand Quality Metric Data? An Evaluation in a Twitter-Derived Sample.

Govindan S, Chopra V, Iwashyna TJ.

J Hosp Med. 2017 Jan;12(1):18-22.

25.

A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

Parameswarappa SG, Reppe K, Geissner A, Ménová P, Govindan S, Calow ADJ, Wahlbrink A, Weishaupt MW, Monnanda BP, Bell RL, Pirofski LA, Suttorp N, Sander LE, Witzenrath M, Pereira CL, Anish C, Seeberger PH.

Cell Chem Biol. 2016 Nov 17;23(11):1407-1416. doi: 10.1016/j.chembiol.2016.09.016. Epub 2016 Nov 3.

26.

Analysis of the invasive edge in primary and secondary oral squamous cell carcinoma: An independent prognostic marker: A retrospective study.

Nadaf A, Bavle RM, Soumya M, D'mello S, Kuriakose MA, Govindan S.

J Oral Maxillofac Pathol. 2016 May-Aug;20(2):239-45. doi: 10.4103/0973-029X.185931.

27.

Web Exclusives. Annals for Hospitalists Inpatient Notes - Sepsis-3 for Hospitalists-Sepsis Without SIRS.

Govindan S, Iwashyna TJ.

Ann Intern Med. 2016 Aug 16;165(4):HO2-3. doi: 10.7326/M16-1507. No abstract available.

PMID:
27538174
28.

The 2016 Guidelines for Hospital-acquired and Ventilator-associated Pneumonia. A Selection Correction?

Govindan S, Hyzy RC.

Am J Respir Crit Care Med. 2016 Sep 15;194(6):658-60. doi: 10.1164/rccm.201607-1447ED. No abstract available.

29.

Antioxidant and anti-aging activities of polysaccharides from Calocybe indica var. APK2.

Govindan S, Johnson EE, Christopher J, Shanmugam J, Thirumalairaj V, Gopalan J.

Exp Toxicol Pathol. 2016 Jun;68(6):329-34. doi: 10.1016/j.etp.2016.04.001. Epub 2016 May 9.

PMID:
27174669
30.

Alterations in Multi-Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein-C.

Taylor EN, Hoffman MP, Barefield DY, Aninwene GE 2nd, Abrishamchi AD, Lynch TL 4th, Govindan S, Osinska H, Robbins J, Sadayappan S, Gilbert RJ.

J Am Heart Assoc. 2016 Mar 15;5(3):e002836. doi: 10.1161/JAHA.115.002836.

31.

Prospects and progress of antibody-drug conjugates in solid tumor therapies.

Govindan SV, Sharkey RM, Goldenberg DM.

Expert Opin Biol Ther. 2016 Jul;16(7):883-93. doi: 10.1517/14712598.2016.1173203. Epub 2016 May 3. Review.

PMID:
27045979
32.

Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex.

Telley L, Govindan S, Prados J, Stevant I, Nef S, Dermitzakis E, Dayer A, Jabaudon D.

Science. 2016 Mar 25;351(6280):1443-6. doi: 10.1126/science.aad8361. Epub 2016 Mar 3.

33.

Cross Reactive Material 197 glycoconjugate vaccines contain privileged conjugation sites.

Möginger U, Resemann A, Martin CE, Parameswarappa S, Govindan S, Wamhoff EC, Broecker F, Suckau D, Pereira CL, Anish C, Seeberger PH, Kolarich D.

Sci Rep. 2016 Feb 4;6:20488. doi: 10.1038/srep20488.

34.

Meta-Analyses of Microarray Datasets Identifies ANO1 and FADD as Prognostic Markers of Head and Neck Cancer.

Reddy RB, Bhat AR, James BL, Govindan SV, Mathew R, Ravindra DR, Hedne N, Illiayaraja J, Kekatpure V, Khora SS, Hicks W, Tata P, Kuriakose MA, Suresh A.

PLoS One. 2016 Jan 25;11(1):e0147409. doi: 10.1371/journal.pone.0147409. eCollection 2016.

35.

Sacituzumab Govitecan, a Novel Antibody--Drug Conjugate, in Patients With Metastatic Platinum-Resistant Urothelial Carcinoma.

Faltas B, Goldenberg DM, Ocean AJ, Govindan SV, Wilhelm F, Sharkey RM, Hajdenberg J, Hodes G, Nanus DM, Tagawa ST.

Clin Genitourin Cancer. 2016 Feb;14(1):e75-9. doi: 10.1016/j.clgc.2015.10.002. Epub 2015 Oct 19.

36.

Oxidative Stress in Dilated Cardiomyopathy Caused by MYBPC3 Mutation.

Lynch TL 4th, Sivaguru M, Velayutham M, Cardounel AJ, Michels M, Barefield D, Govindan S, dos Remedios C, van der Velden J, Sadayappan S.

Oxid Med Cell Longev. 2015;2015:424751. doi: 10.1155/2015/424751. Epub 2015 Oct 5.

37.

Molecular Screen Identifies Cardiac Myosin-Binding Protein-C as a Protein Kinase G-Iα Substrate.

Thoonen R, Giovanni S, Govindan S, Lee DI, Wang GR, Calamaras TD, Takimoto E, Kass DA, Sadayappan S, Blanton RM.

Circ Heart Fail. 2015 Nov;8(6):1115-22. doi: 10.1161/CIRCHEARTFAILURE.115.002308. Epub 2015 Oct 18.

38.

Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation.

Kumar M, Govindan S, Zhang M, Khairallah RJ, Martin JL, Sadayappan S, de Tombe PP.

J Biol Chem. 2015 Dec 4;290(49):29241-9. doi: 10.1074/jbc.M115.686790. Epub 2015 Oct 9.

39.

Migration Speed of Cajal-Retzius Cells Modulated by Vesicular Trafficking Controls the Size of Higher-Order Cortical Areas.

Barber M, Arai Y, Morishita Y, Vigier L, Causeret F, Borello U, Ledonne F, Coppola E, Contremoulins V, Pfrieger FW, Tissir F, Govindan S, Jabaudon D, Proux-Gillardeaux V, Galli T, Pierani A.

Curr Biol. 2015 Oct 5;25(19):2466-78. doi: 10.1016/j.cub.2015.08.028. Epub 2015 Sep 17.

40.

Enhanced Delivery of SN-38 to Human Tumor Xenografts with an Anti-Trop-2-SN-38 Antibody Conjugate (Sacituzumab Govitecan).

Sharkey RM, McBride WJ, Cardillo TM, Govindan SV, Wang Y, Rossi EA, Chang CH, Goldenberg DM.

Clin Cancer Res. 2015 Nov 15;21(22):5131-8. doi: 10.1158/1078-0432.CCR-15-0670. Epub 2015 Jun 23.

41.

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC).

Goldenberg DM, Cardillo TM, Govindan SV, Rossi EA, Sharkey RM.

Oncotarget. 2015 Sep 8;6(26):22496-512.

42.

A Systematic Assessment of the Surviving Sepsis Campaign's Evidence Supporting the Care of Patients with Severe Sepsis on the Wards.

Odden AJ, Govindan S, Sheth J, Iwashyna TJ.

Ann Am Thorac Soc. 2015 Jun;12(6):956-8. doi: 10.1513/AnnalsATS.201502-096LE. No abstract available.

43.

Asymmetric cell division of granule neuron progenitors in the external granule layer of the mouse cerebellum.

Haldipur P, Sivaprakasam I, Periasamy V, Govindan S, Mani S.

Biol Open. 2015 May 15;4(7):865-72. doi: 10.1242/bio.009886.

44.

ABCDE, but in that order? A cross-sectional survey of Michigan intensive care unit sedation, delirium, and early mobility practices.

Miller MA, Govindan S, Watson SR, Hyzy RC, Iwashyna TJ.

Ann Am Thorac Soc. 2015 Jul;12(7):1066-71. doi: 10.1513/AnnalsATS.201501-066OC.

45.

Establishment and characterization of triple drug resistant head and neck squamous cell carcinoma cell lines.

Govindan SV, Kulsum S, Pandian RS, Das D, Seshadri M, Hicks W Jr, Kuriakose MA, Suresh A.

Mol Med Rep. 2015 Aug;12(2):3025-32. doi: 10.3892/mmr.2015.3768. Epub 2015 May 12.

PMID:
25962396
46.

First-in-Human Trial of a Novel Anti-Trop-2 Antibody-SN-38 Conjugate, Sacituzumab Govitecan, for the Treatment of Diverse Metastatic Solid Tumors.

Starodub AN, Ocean AJ, Shah MA, Guarino MJ, Picozzi VJ Jr, Vahdat LT, Thomas SS, Govindan SV, Maliakal PP, Wegener WA, Hamburger SA, Sharkey RM, Goldenberg DM.

Clin Cancer Res. 2015 Sep 1;21(17):3870-8. doi: 10.1158/1078-0432.CCR-14-3321. Epub 2015 May 5.

47.

Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody-Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers.

Cardillo TM, Govindan SV, Sharkey RM, Trisal P, Arrojo R, Liu D, Rossi EA, Chang CH, Goldenberg DM.

Bioconjug Chem. 2015 May 20;26(5):919-31. doi: 10.1021/acs.bioconjchem.5b00223. Epub 2015 May 8.

PMID:
25915780
48.

Molecular epidemiology of methicillin resistant staphylococcus aureus colonizing the anterior Nares of school children of Udupi Taluk.

Govindan S, Maroli AS, Ciraj AM, Bairy I.

Indian J Med Microbiol. 2015 Feb;33 Suppl:129-33. doi: 10.4103/0255-0857.150919. Erratum in: Indian J Med Microbiol. 2015 Apr-Jun;33(2):337.

49.

A hypertrophic cardiomyopathy-associated MYBPC3 mutation common in populations of South Asian descent causes contractile dysfunction.

Kuster DW, Govindan S, Springer TI, Martin JL, Finley NL, Sadayappan S.

J Biol Chem. 2015 Feb 27;290(9):5855-67. doi: 10.1074/jbc.M114.607911. Epub 2015 Jan 12.

50.

Aspergillus flavus impairs antioxidative enzymes of Sternochetus mangiferae during mycosis.

Jayanthi K, Ayyasamy A, Kempraj V, Aurade RM, Govindan S, Verghese A.

J Invertebr Pathol. 2015 Jan;124:73-7. doi: 10.1016/j.jip.2014.11.004. Epub 2014 Nov 15.

PMID:
25446036

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