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Items: 3

1.

ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models.

Cramer PE, Cirrito JR, Wesson DW, Lee CY, Karlo JC, Zinn AE, Casali BT, Restivo JL, Goebel WD, James MJ, Brunden KR, Wilson DA, Landreth GE.

Science. 2012 Mar 23;335(6075):1503-6. doi: 10.1126/science.1217697. Epub 2012 Feb 9.

2.

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans.

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D'Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI.

Proc Natl Acad Sci U S A. 2011 Sep 6;108(36):14968-73. doi: 10.1073/pnas.1107411108. Epub 2011 Aug 22.

3.

Opposing synaptic regulation of amyloid-β metabolism by NMDA receptors in vivo.

Verges DK, Restivo JL, Goebel WD, Holtzman DM, Cirrito JR.

J Neurosci. 2011 Aug 3;31(31):11328-37. doi: 10.1523/JNEUROSCI.0607-11.2011.

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