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Multibreed genomic prediction using multitrait genomic residual maximum likelihood and multitask Bayesian variable selection.

Calus MPL, Goddard ME, Wientjes YCJ, Bowman PJ, Hayes BJ.

J Dairy Sci. 2018 Mar 14. pii: S0022-0302(18)30227-3. doi: 10.3168/jds.2017-13366. [Epub ahead of print]


Donor Pre-treatment with nebulized complement C3a Receptor antagonist mitigates brain-death induced immunological injury post-lung transplant.

Cheng Q, Patel K, Lei B, Rucker L, Allen DP, Zhu P, Vasu C, Martins PN, Goddard M, Nadig SN, Atkinson C.

Am J Transplant. 2018 Mar 5. doi: 10.1111/ajt.14717. [Epub ahead of print]


Meta-analysis of genome-wide association studies for cattle stature identifies common genes that regulate body size in mammals.

Bouwman AC, Daetwyler HD, Chamberlain AJ, Ponce CH, Sargolzaei M, Schenkel FS, Sahana G, Govignon-Gion A, Boitard S, Dolezal M, Pausch H, Brøndum RF, Bowman PJ, Thomsen B, Guldbrandtsen B, Lund MS, Servin B, Garrick DJ, Reecy J, Vilkki J, Bagnato A, Wang M, Hoff JL, Schnabel RD, Taylor JF, Vinkhuyzen AAE, Panitz F, Bendixen C, Holm LE, Gredler B, Hozé C, Boussaha M, Sanchez MP, Rocha D, Capitan A, Tribout T, Barbat A, Croiseau P, Drögemüller C, Jagannathan V, Vander Jagt C, Crowley JJ, Bieber A, Purfield DC, Berry DP, Emmerling R, Götz KU, Frischknecht M, Russ I, Sölkner J, Van Tassell CP, Fries R, Stothard P, Veerkamp RF, Boichard D, Goddard ME, Hayes BJ.

Nat Genet. 2018 Mar;50(3):362-367. doi: 10.1038/s41588-018-0056-5. Epub 2018 Feb 19.


Gene expression analysis of blood, liver, and muscle in cattle divergently selected for high and low residual feed intake.

Khansefid M, Millen CA, Chen Y, Pryce JE, Chamberlain AJ, Vander Jagt CJ, Gondro C, Goddard ME.

J Anim Sci. 2017 Nov;95(11):4764-4775. doi: 10.2527/jas2016.1320.


Grapevine Botryosphaeria dieback fungi have specific aggressiveness factor repertory involved in wood decay and stilbene metabolization.

Stempien E, Goddard ML, Wilhelm K, Tarnus C, Bertsch C, Chong J.

PLoS One. 2017 Dec 20;12(12):e0188766. doi: 10.1371/journal.pone.0188766. eCollection 2017.


Outcome after heart transplantation from donation after circulatory-determined death donors.

Messer S, Page A, Axell R, Berman M, Hernández-Sánchez J, Colah S, Parizkova B, Valchanov K, Dunning J, Pavlushkov E, Balasubramanian SK, Parameshwar J, Omar YA, Goddard M, Pettit S, Lewis C, Kydd A, Jenkins D, Watson CJ, Sudarshan C, Catarino P, Findlay M, Ali A, Tsui S, Large SR.

J Heart Lung Transplant. 2017 Dec;36(12):1311-1318. doi: 10.1016/j.healun.2017.10.021. Epub 2017 Oct 24. Erratum in: J Heart Lung Transplant. 2018 Apr;37(4):535.


Meta-analysis of sequence-based association studies across three cattle breeds reveals 25 QTL for fat and protein percentages in milk at nucleotide resolution.

Pausch H, Emmerling R, Gredler-Grandl B, Fries R, Daetwyler HD, Goddard ME.

BMC Genomics. 2017 Nov 9;18(1):853. doi: 10.1186/s12864-017-4263-8.


From vineyard to winery: a source map of microbial diversity driving wine fermentation.

Morrison-Whittle P, Goddard MR.

Environ Microbiol. 2018 Jan;20(1):75-84. doi: 10.1111/1462-2920.13960. Epub 2017 Nov 10.


Secreted proteins produced by fungi associated with Botryosphaeria dieback trigger distinct defense responses in Vitis vinifera and Vitis rupestris cells.

Stempien E, Goddard ML, Leva Y, Bénard-Gellon M, Laloue H, Farine S, Kieffer-Mazet F, Tarnus C, Bertsch C, Chong J.

Protoplasma. 2018 Mar;255(2):613-628. doi: 10.1007/s00709-017-1175-z. Epub 2017 Oct 17.


Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library.

Johnston KL, Cook DAN, Berry NG, David Hong W, Clare RH, Goddard M, Ford L, Nixon GL, O'Neill PM, Ward SA, Taylor MJ.

Sci Adv. 2017 Sep 27;3(9):eaao1551. doi: 10.1126/sciadv.aao1551. eCollection 2017 Sep.


Multi-breed genomic prediction using Bayes R with sequence data and dropping variants with a small effect.

van den Berg I, Bowman PJ, MacLeod IM, Hayes BJ, Wang T, Bolormaa S, Goddard ME.

Genet Sel Evol. 2017 Sep 21;49(1):70. doi: 10.1186/s12711-017-0347-9.


Concepts, estimation and interpretation of SNP-based heritability.

Yang J, Zeng J, Goddard ME, Wray NR, Visscher PM.

Nat Genet. 2017 Aug 30;49(9):1304-1310. doi: 10.1038/ng.3941.


Genome-wide comparative analyses of correlated and uncorrelated phenotypes identify major pleiotropic variants in dairy cattle.

Xiang R, MacLeod IM, Bolormaa S, Goddard ME.

Sci Rep. 2017 Aug 23;7(1):9248. doi: 10.1038/s41598-017-09788-9.


Multiple-trait QTL mapping and genomic prediction for wool traits in sheep.

Bolormaa S, Swan AA, Brown DJ, Hatcher S, Moghaddar N, van der Werf JH, Goddard ME, Daetwyler HD.

Genet Sel Evol. 2017 Aug 15;49(1):62. doi: 10.1186/s12711-017-0337-y.


Application of a Bayesian non-linear model hybrid scheme to sequence data for genomic prediction and QTL mapping.

Wang T, Chen YP, MacLeod IM, Pryce JE, Goddard ME, Hayes BJ.

BMC Genomics. 2017 Aug 15;18(1):618. doi: 10.1186/s12864-017-4030-x.


Can we make genomic selection 100% accurate?

Goddard ME.

J Anim Breed Genet. 2017 Aug;134(4):287-288. doi: 10.1111/jbg.12281. No abstract available.


Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis.

Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T, Saliba D, Goddard ME, Sansom SN, Goncalves I, Krams R, Udalova IA, Monaco C.

Circulation. 2017 Sep 19;136(12):1140-1154. doi: 10.1161/CIRCULATIONAHA.117.027844. Epub 2017 Jul 11.


Identifying primary care quality indicators for people with serious mental illness: a systematic review.

Kronenberg C, Doran T, Goddard M, Kendrick T, Gilbody S, Dare CR, Aylott L, Jacobs R.

Br J Gen Pract. 2017 Aug;67(661):e519-e530. doi: 10.3399/bjgp17X691721. Epub 2017 Jul 3.


Imaging vulnerable plaques by targeting inflammation in atherosclerosis using fluorescent-labeled dual-ligand microparticles of iron oxide and magnetic resonance imaging.

Chan JMS, Monaco C, Wylezinska-Arridge M, Tremoleda JL, Cole JE, Goddard M, Cheung MSH, Bhakoo KK, Gibbs RGJ.

J Vasc Surg. 2017 Jun 22. pii: S0741-5214(17)31249-1. doi: 10.1016/j.jvs.2017.04.046. [Epub ahead of print]


Autonomy and performance in the public sector: the experience of English NHS hospitals.

Verzulli R, Jacobs R, Goddard M.

Eur J Health Econ. 2017 Jun 15. doi: 10.1007/s10198-017-0906-6. [Epub ahead of print]


Long-term effects of systemic gene therapy in a canine model of myotubular myopathy.

Elverman M, Goddard MA, Mack D, Snyder JM, Lawlor MW, Meng H, Beggs AH, Buj-Bello A, Poulard K, Marsh AP, Grange RW, Kelly VE, Childers MK.

Muscle Nerve. 2017 Nov;56(5):943-953. doi: 10.1002/mus.25658. Epub 2017 May 22.


Systemic AAV8-Mediated Gene Therapy Drives Whole-Body Correction of Myotubular Myopathy in Dogs.

Mack DL, Poulard K, Goddard MA, Latournerie V, Snyder JM, Grange RW, Elverman MR, Denard J, Veron P, Buscara L, Le Bec C, Hogrel JY, Brezovec AG, Meng H, Yang L, Liu F, O'Callaghan M, Gopal N, Kelly VE, Smith BK, Strande JL, Mavilio F, Beggs AH, Mingozzi F, Lawlor MW, Buj-Bello A, Childers MK.

Mol Ther. 2017 Apr 5;25(4):839-854. doi: 10.1016/j.ymthe.2017.02.004. Epub 2017 Feb 22.


Evaluation of the accuracy of imputed sequence variant genotypes and their utility for causal variant detection in cattle.

Pausch H, MacLeod IM, Fries R, Emmerling R, Bowman PJ, Daetwyler HD, Goddard ME.

Genet Sel Evol. 2017 Feb 21;49(1):24. doi: 10.1186/s12711-017-0301-x.


Beyond Ecosystem Services: Valuing the Invaluable.

Gunton RM, van Asperen EN, Basden A, Bookless D, Araya Y, Hanson DR, Goddard MA, Otieno G, Jones GO.

Trends Ecol Evol. 2017 Apr;32(4):249-257. doi: 10.1016/j.tree.2017.01.002. Epub 2017 Feb 16. Review.


Using information of relatives in genomic prediction to apply effective stratified medicine.

Lee SH, Weerasinghe WM, Wray NR, Goddard ME, van der Werf JH.

Sci Rep. 2017 Feb 9;7:42091. doi: 10.1038/srep42091.


Integrated Care: A Pill for All Ills?

Goddard M, Mason AR.

Int J Health Policy Manag. 2016 Aug 13;6(1):1-3. doi: 10.15171/ijhpm.2016.111.


Including nonadditive genetic effects in mating programs to maximize dairy farm profitability.

Aliloo H, Pryce JE, González-Recio O, Cocks BG, Goddard ME, Hayes BJ.

J Dairy Sci. 2017 Feb;100(2):1203-1222. doi: 10.3168/jds.2016-11261. Epub 2016 Dec 9.


Functional assessment and transplantation of the donor heart after circulatory death.

Messer SJ, Axell RG, Colah S, White PA, Ryan M, Page AA, Parizkova B, Valchanov K, White CW, Freed DH, Ashley E, Dunning J, Goddard M, Parameshwar J, Watson CJ, Krieg T, Ali A, Tsui S, Large SR.

J Heart Lung Transplant. 2016 Dec;35(12):1443-1452. doi: 10.1016/j.healun.2016.07.004. Epub 2016 Jul 16.


Hierarchical filters determine community assembly of urban species pools.

Aronson MF, Nilon CH, Lepczyk CA, Parker TS, Warren PS, Cilliers SS, Goddard MA, Hahs AK, Herzog C, Katti M, La Sorte FA, Williams NS, Zipperer W.

Ecology. 2016 Nov;97(11):2952-2963. doi: 10.1002/ecy.1535.


Molecular taxonomic analysis of the plant associations of adult pollen beetles (Nitidulidae: Meligethinae), and the population structure of Brassicogethes aeneus.

Ouvrard P, Hicks DM, Mouland M, Nicholls JA, Baldock KC, Goddard MA, Kunin WE, Potts SG, Thieme T, Veromann E, Stone GN.

Genome. 2016 Dec;59(12):1101-1116. Epub 2016 Jul 18.


Leveraging genetically simple traits to identify small-effect variants for complex phenotypes.

Kemper KE, Littlejohn MD, Lopdell T, Hayes BJ, Bennett LE, Williams RP, Xu XQ, Visscher PM, Carrick MJ, Goddard ME.

BMC Genomics. 2016 Nov 3;17(1):858.


European derived Saccharomyces cerevisiae colonisation of New Zealand vineyards aided by humans.

Gayevskiy V, Lee S, Goddard MR.

FEMS Yeast Res. 2016 Nov;16(7). pii: fow091. Epub 2016 Oct 15.


Health Equity Indicators for the English NHS: a longitudinal whole-population study at the small-area level.

Cookson R, Asaria M, Ali S, Ferguson B, Fleetcroft R, Goddard M, Goldblatt P, Laudicella M, Raine R.

Southampton (UK): NIHR Journals Library; 2016 Sep.


GCTA-GREML accounts for linkage disequilibrium when estimating genetic variance from genome-wide SNPs.

Yang J, Lee SH, Wray NR, Goddard ME, Visscher PM.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4579-80. doi: 10.1073/pnas.1602743113. Epub 2016 Jul 25. No abstract available.


Genetics of complex traits: prediction of phenotype, identification of causal polymorphisms and genetic architecture.

Goddard ME, Kemper KE, MacLeod IM, Chamberlain AJ, Hayes BJ.

Proc Biol Sci. 2016 Jul 27;283(1835). pii: 20160569. doi: 10.1098/rspb.2016.0569. Review.


Native lung pneumonectomy for post-transplantation lymphoproliferative disorder refractory to rituximab following contralateral lung transplantation.

Roman M, Parmar J, Goddard M, Solli P.

Interact Cardiovasc Thorac Surg. 2016 Nov;23(5):841-843. Epub 2016 Jul 15.


Food for Pollinators: Quantifying the Nectar and Pollen Resources of Urban Flower Meadows.

Hicks DM, Ouvrard P, Baldock KC, Baude M, Goddard MA, Kunin WE, Mitschunas N, Memmott J, Morse H, Nikolitsi M, Osgathorpe LM, Potts SG, Robertson KM, Scott AV, Sinclair F, Westbury DB, Stone GN.

PLoS One. 2016 Jun 24;11(6):e0158117. doi: 10.1371/journal.pone.0158117. eCollection 2016.


Plaque Structural Stress Estimations Improve Prediction of Future Major Adverse Cardiovascular Events After Intracoronary Imaging.

Brown AJ, Teng Z, Calvert PA, Rajani NK, Hennessy O, Nerlekar N, Obaid DR, Costopoulos C, Huang Y, Hoole SP, Goddard M, West NE, Gillard JH, Bennett MR.

Circ Cardiovasc Imaging. 2016 Jun;9(6). pii: e004172. doi: 10.1161/CIRCIMAGING.115.004172.


Copy number variants in the sheep genome detected using multiple approaches.

Jenkins GM, Goddard ME, Black MA, Brauning R, Auvray B, Dodds KG, Kijas JW, Cockett N, McEwan JC.

BMC Genomics. 2016 Jun 8;17:441. doi: 10.1186/s12864-016-2754-7.


Prediction of non-muscle invasive bladder cancer outcomes assessed by innovative multimarker prognostic models.

López de Maturana E, Picornell A, Masson-Lecomte A, Kogevinas M, Márquez M, Carrato A, Tardón A, Lloreta J, García-Closas M, Silverman D, Rothman N, Chanock S, Real FX, Goddard ME, Malats N; SBC/EPICURO Study Investigators.

BMC Cancer. 2016 Jun 3;16:351. doi: 10.1186/s12885-016-2361-7.


Risk of Care Home Placement following Acute Hospital Admission: Effects of a Pay-for-Performance Scheme for Dementia.

Kasteridis P, Mason A, Goddard M, Jacobs R, Santos R, Rodriguez-Sanchez B, McGonigal G.

PLoS One. 2016 May 26;11(5):e0155850. doi: 10.1371/journal.pone.0155850. eCollection 2016.


Risk of psychiatric illness from advanced paternal age is not predominantly from de novo mutations.

Gratten J, Wray NR, Peyrot WJ, McGrath JJ, Visscher PM, Goddard ME.

Nat Genet. 2016 Jul;48(7):718-24. doi: 10.1038/ng.3577. Epub 2016 May 23.


Inflammatory-Related Genetic Variants in Non-Muscle-Invasive Bladder Cancer Prognosis: A Multimarker Bayesian Assessment.

Masson-Lecomte A, López de Maturana E, Goddard ME, Picornell A, Rava M, González-Neira A, Márquez M, Carrato A, Tardon A, Lloreta J, Garcia-Closas M, Silverman D, Rothman N, Kogevinas M, Allory Y, Chanock SJ, Real FX, Malats N; SBC/EPICURO Study Investigators.

Cancer Epidemiol Biomarkers Prev. 2016 Jul;25(7):1144-50. doi: 10.1158/1055-9965.EPI-15-0894. Epub 2016 May 6.


Microbiology: Mixing Wine, Chocolate, and Coffee.

Goddard MR.

Curr Biol. 2016 Apr 4;26(7):R275-7. doi: 10.1016/j.cub.2016.02.046.


Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets.

Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, Montgomery GW, Goddard ME, Wray NR, Visscher PM, Yang J.

Nat Genet. 2016 May;48(5):481-7. doi: 10.1038/ng.3538. Epub 2016 Mar 28.


Complex Multiplexing of Reward-Cue- and Licking-Movement-Related Activity in Single Midline Thalamus Neurons.

Li Y, Lindemann C, Goddard MJ, Hyland BI.

J Neurosci. 2016 Mar 23;36(12):3567-78. doi: 10.1523/JNEUROSCI.1107-15.2016.


Detailed phenotyping identifies genes with pleiotropic effects on body composition.

Bolormaa S, Hayes BJ, van der Werf JH, Pethick D, Goddard ME, Daetwyler HD.

BMC Genomics. 2016 Mar 12;17:224. doi: 10.1186/s12864-016-2538-0.


Exploiting biological priors and sequence variants enhances QTL discovery and genomic prediction of complex traits.

MacLeod IM, Bowman PJ, Vander Jagt CJ, Haile-Mariam M, Kemper KE, Chamberlain AJ, Schrooten C, Hayes BJ, Goddard ME.

BMC Genomics. 2016 Feb 27;17:144. doi: 10.1186/s12864-016-2443-6.


Molecular evolution: Sex accelerates adaptation.

Goddard MR.

Nature. 2016 Mar 10;531(7593):176-7. doi: 10.1038/nature17304. Epub 2016 Feb 24. No abstract available.


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