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Design and rationale of the Study of Etanercept and Methotrexate in Combination or as Monotherapy in Subjects with Psoriatic Arthritis (SEAM-PsA).

Mease PJ, Gladman DD, Samad AS, Coates LC, Liu LXH, Aras GA, Collier DH, Chung JB.

RMD Open. 2018 Feb 3;4(1):e000606. doi: 10.1136/rmdopen-2017-000606. eCollection 2018.


Gaps in Diagnosis and Treatment of Cardiovascular Risk Factors in Patients with Psoriatic Disease: An International Multicenter Study.

Eder L, Harvey P, Chandran V, Rosen CF, Dutz J, Elder JT, Rahman P, Ritchlin CT, Rohekar S, Hayday R, Barac S, Feld J, Zisman D, Gladman DD.

J Rheumatol. 2018 Mar;45(3):378-384. doi: 10.3899/jrheum.170379. Epub 2018 Feb 1.


Glucocorticoid use and factors associated with variability in this use in the Systemic Lupus International Collaborating Clinics Inception Cohort.

Little J, Parker B, Lunt M, Hanly JG, Urowitz MB, Clarke AE, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Wallace DJ, Merrill JT, Buyon J, Isenberg DA, Rahman A, Ginzler EM, Petri M, Dooley MA, Fortin P, Gladman DD, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Mackay M, Alarcón GS, Manzi S, Nived O, Jönsen A, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Sam Lim S, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Sanchez-Guerrero J, Bruce IN.

Rheumatology (Oxford). 2018 Jan 18. doi: 10.1093/rheumatology/kex444. [Epub ahead of print]


Current and future therapies for SLE: obstacles and recommendations for the development of novel treatments.

Touma Z, Gladman DD.

Lupus Sci Med. 2017 Dec 17;4(1):e000239. doi: 10.1136/lupus-2017-000239. eCollection 2017. Review.


Smoking Is the Most Significant Modifiable Lung Cancer Risk Factor in Systemic Lupus Erythematosus.

Bernatsky S, Ramsey-Goldman R, Petri M, Urowitz MB, Gladman DD, Fortin PR, Yelin EH, Ginzler E, Hanly JG, Peschken C, Gordon C, Nived O, Aranow C, Bae SC, Isenberg D, Rahman A, Hansen JE, Pierre YS, Clarke AE.

J Rheumatol. 2018 Mar;45(3):393-396. doi: 10.3899/jrheum.170652. Epub 2018 Jan 15.


Cerebrovascular Events in Systemic Lupus Erythematosus.

Hanly JG, Li Q, Su L, Urowitz MB, Gordon C, Bae SC, Romero-Diaz J, Sanchez-Guerrero J, Bernatsky S, Clarke AE, Wallace DJ, Isenberg DA, Rahman A, Merrill JT, Fortin P, Gladman DD, Bruce IN, Petri M, Ginzler EM, Dooley MA, Steinsson K, Ramsey-Goldman R, Zoma AA, Manzi S, Nived O, Jonsen A, Khamashta MA, Alarcón GS, Chatham W, van Vollenhoven RF, Aranow C, Mackay M, Ruiz-Irastorza G, Ramos-Casals M, Lim SS, Inanc M, Kalunian KC, Jacobsen S, Peschken CA, Kamen DL, Askanase A, Theriault C, Farewell V.

Arthritis Care Res (Hoboken). 2018 Jan 5. doi: 10.1002/acr.23509. [Epub ahead of print]


Efficacy and Safety of Ixekizumab in Patients with Active Psoriatic Arthritis: 52-week Results from a Phase III Study (SPIRIT-P1).

van der Heijde D, Gladman DD, Kishimoto M, Okada M, Rathmann SS, Moriarty SR, Shuler CL, Carlier H, Benichou O, Mease PJ.

J Rheumatol. 2018 Mar;45(3):367-377. doi: 10.3899/jrheum.170429. Epub 2017 Dec 15.


Prediction and benefits of minimal disease activity in patients with psoriatic arthritis and active skin disease in the ADEPT trial.

Mease PJ, Kavanaugh A, Coates LC, McInnes IB, Hojnik M, Zhang Y, Anderson JK, Dorr AP, Gladman DD.

RMD Open. 2017 Jul 18;3(1):e000415. doi: 10.1136/rmdopen-2016-000415. eCollection 2017.


Characteristic and Outcome of Psoriatic Arthritis Patients with Hyperuricemia.

AlJohani R, Polachek A, Ye JY, Chandran V, Gladman DD.

J Rheumatol. 2018 Feb;45(2):213-217. doi: 10.3899/jrheum.170384. Epub 2017 Dec 1.


Economic evaluation of lupus nephritis in the Systemic Lupus International Collaborating Clinics inception cohort using a multistate model approach.

Barber MRW, Hanly JG, Su L, Urowitz MB, Pierre YS, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Wallace DJ, Isenberg DA, Rahman A, Ginzler EM, Petri M, Bruce IN, Fortin PR, Gladman DD, Sanchez-Guerrero J, Ramsey-Goldman R, Khamashta MA, Aranow C, Mackay M, Alarcón GS, Manzi S, Nived O, Jönsen A, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Sam Lim S, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Theriault C, Farewell V, Clarke AE.

Arthritis Care Res (Hoboken). 2017 Nov 28. doi: 10.1002/acr.23480. [Epub ahead of print]


Addressing comorbidities in psoriatic disease.

Patel P, Rosen CF, Chandran V, Ye YJ, Gladman DD.

Rheumatol Int. 2018 Feb;38(2):219-227. doi: 10.1007/s00296-017-3895-y. Epub 2017 Nov 28.


Th17 gene expression in psoriatic arthritis synovial fluid and peripheral blood compared to osteoarthritis and cutaneous psoriasis.

Abji F, Pollock RA, Liang K, Chandran V, Gladman DD.

Clin Exp Rheumatol. 2017 Nov 9. [Epub ahead of print]


More Consistent Antimalarial Intake in First 5 Years of Disease Is Associated with Better Prognosis in Patients with Systemic Lupus Erythematosus.

Pakchotanon R, Gladman DD, Su J, Urowitz MB.

J Rheumatol. 2018 Jan;45(1):90-94. doi: 10.3899/jrheum.170645. Epub 2017 Nov 15.


Evolution of Risk Factors for Atherosclerotic Cardiovascular Events in Systemic Lupus Erythematosus: A Longterm Prospective Study.

Tselios K, Gladman DD, Su J, Ace O, Urowitz MB.

J Rheumatol. 2017 Dec;44(12):1841-1849. doi: 10.3899/jrheum.161121. Epub 2017 Nov 1.


Association of Tumor Necrosis Factor Inhibitor Treatment With Reduced Indices of Subclinical Atherosclerosis in Patients With Psoriatic Disease.

Eder L, Joshi AA, Dey AK, Cook R, Siegel EL, Gladman DD, Mehta NN.

Arthritis Rheumatol. 2018 Mar;70(3):408-416. doi: 10.1002/art.40366. Epub 2018 Feb 6.


Rituximab for Sight-Threatening Lupus-Related Retinal Vasculitis.

Tselios K, Lam WC, Urowitz MB, Gladman DD.

J Clin Rheumatol. 2018 Mar;24(2):93-94. doi: 10.1097/RHU.0000000000000600. No abstract available.


A systematic review of measurement properties of patient reported outcome measures in psoriatic arthritis: A GRAPPA-OMERACT initiative.

Højgaard P, Klokker L, Orbai AM, Holmsted K, Bartels EM, Leung YY, Goel N, de Wit M, Gladman DD, Mease P, Dreyer L, Kristensen LE, FitzGerald O, Tillett W, Gossec L, Helliwell P, Strand V, Ogdie A, Terwee CB, Christensen R.

Semin Arthritis Rheum. 2017 Sep 9. pii: S0049-0172(17)30182-8. doi: 10.1016/j.semarthrit.2017.09.002. [Epub ahead of print] Review.


Antimalarial-induced cardiomyopathy: a systematic review of the literature.

Tselios K, Deeb M, Gladman DD, Harvey P, Urowitz MB.

Lupus. 2017 Jan 1:961203317734922. doi: 10.1177/0961203317734922. [Epub ahead of print]


Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.

Dand N, Mucha S, Tsoi LC, Mahil SK, Stuart PE, Arnold A, Baurecht H, Burden AD, Callis Duffin K, Chandran V, Curtis CJ, Das S, Ellinghaus D, Ellinghaus E, Enerback C, Esko T, Gladman DD, Griffiths CEM, Gudjonsson JE, Hoffman P, Homuth G, Hüffmeier U, Krueger GG, Laudes M, Lee SH, Lieb W, Lim HW, Löhr S, Mrowietz U, Müller-Nurayid M, Nöthen M, Peters A, Rahman P, Reis A, Reynolds NJ, Rodriguez E, Schmidt CO, Spain SL, Strauch K, Tejasvi T, Voorhees JJ, Warren RB, Weichenthal M, Weidinger S, Zawistowski M, Nair RP, Capon F, Smith CH, Trembath RC, Abecasis GR, Elder JT, Franke A, Simpson MA, Barker JN.

Hum Mol Genet. 2017 Nov 1;26(21):4301-4313. doi: 10.1093/hmg/ddx328.


Cost-effectiveness analysis of secukinumab for the treatment of active psoriatic arthritis: a Canadian perspective.

Goeree R, Chiva-Razavi S, Gunda P, Graham CN, Miles L, Nikoglou E, Jugl SM, Gladman DD.

J Med Econ. 2018 Feb;21(2):163-173. doi: 10.1080/13696998.2017.1384737. Epub 2017 Oct 19.


Sustained complete renal remission is a predictor of reduced mortality, chronic kidney disease and end-stage renal disease in lupus nephritis.

Pakchotanon R, Gladman DD, Su J, Urowitz MB.

Lupus. 2018 Mar;27(3):468-474. doi: 10.1177/0961203317726376. Epub 2017 Aug 31.


The association between sonographic enthesitis and radiographic damage in psoriatic arthritis.

Polachek A, Cook R, Chandran V, Gladman DD, Eder L.

Arthritis Res Ther. 2017 Aug 15;19(1):189. doi: 10.1186/s13075-017-1399-5.


Association of variably expressed KIR3dl1 alleles with psoriatic disease.

Berinstein J, Pollock R, Pellett F, Thavaneswaran A, Chandran V, Gladman DD.

Clin Rheumatol. 2017 Oct;36(10):2261-2266. doi: 10.1007/s10067-017-3784-5. Epub 2017 Aug 11.


Shrinking lung syndrome in systemic lupus erythematosus: a single-centre experience.

Deeb M, Tselios K, Gladman DD, Su J, Urowitz MB.

Lupus. 2018 Mar;27(3):365-371. doi: 10.1177/0961203317722411. Epub 2017 Jul 31.


GRAPPA-OMERACT initiative to standardise outcomes in psoriatic arthritis clinical trials and longitudinal observational studies.

Tillett W, Orbai AM, Ogdie A, Leung YY, Strand V, Gladman DD, Mease PJ, Coates LC; GRAPPA OMERACT Psoriatic Arthritis working group.

Ann Rheum Dis. 2017 Jul 26. pii: annrheumdis-2017-212004. doi: 10.1136/annrheumdis-2017-212004. [Epub ahead of print] No abstract available.


Transancestral mapping and genetic load in systemic lupus erythematosus.

Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ.

Nat Commun. 2017 Jul 17;8:16021. doi: 10.1038/ncomms16021.


From Childhood to Adulthood: Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus.

Lim LSH, Pullenayegum E, Feldman BM, Lim L, Gladman DD, Silverman ED.

Arthritis Care Res (Hoboken). 2017 Jul 13. doi: 10.1002/acr.23319. [Epub ahead of print]


Magnetic Resonance Imaging in Psoriatic Arthritis: A Descriptive Study of Indications, Features and Effect on Treatment Change.

Maldonado-Ficco H, Sheane BJ, Thavaneswaran A, Chandran V, Gladman DD.

J Clin Rheumatol. 2017 Aug;23(5):243-245. doi: 10.1097/RHU.0000000000000558.



Urowitz MB, Gladman DD.

Arthritis Care Res (Hoboken). 2017 Dec;69(12):1934. doi: 10.1002/acr.23309. No abstract available.


Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force.

Smolen JS, Schöls M, Braun J, Dougados M, FitzGerald O, Gladman DD, Kavanaugh A, Landewé R, Mease P, Sieper J, Stamm T, Wit M, Aletaha D, Baraliakos X, Betteridge N, Bosch FVD, Coates LC, Emery P, Gensler LS, Gossec L, Helliwell P, Jongkees M, Kvien TK, Inman RD, McInnes IB, Maccarone M, Machado PM, Molto A, Ogdie A, Poddubnyy D, Ritchlin C, Rudwaleit M, Tanew A, Thio B, Veale D, Vlam K, Heijde DV.

Ann Rheum Dis. 2018 Jan;77(1):3-17. doi: 10.1136/annrheumdis-2017-211734. Epub 2017 Jul 6. Erratum in: Ann Rheum Dis. 2018 Mar;77(3):472.


Sleep Disturbance in Psoriatic Disease: Prevalence and Associated Factors.

Wong ITY, Chandran V, Li S, Gladman DD.

J Rheumatol. 2017 Sep;44(9):1369-1374. doi: 10.3899/jrheum.161330. Epub 2017 Jun 15.


Hospitalizations in Patients with Systemic Lupus Erythematosus in an Academic Health Science Center.

Gu K, Gladman DD, Su J, Urowitz MB.

J Rheumatol. 2017 Aug;44(8):1173-1178. doi: 10.3899/jrheum.170072. Epub 2017 Jun 15.


Treating Psoriasis and Psoriatic Arthritis: Position Paper on Applying the Treat-to-target Concept to Canadian Daily Practice.

Gladman DD, Poulin Y, Adams K, Bourcier M, Barac S, Barber K, Chandran V, Dutz J, Flanagan C, Gooderham MJ, Gulliver WP, Ho VC, Hong CH, Karsh J, Khraishi MM, Lynde CW, Papp KA, Rahman P, Rohekar S, Rosen CF, Russell AS, Vender RB, Yeung J, Ziouzina O, Zummer M.

J Rheumatol. 2017 Apr;44(4):519-534. doi: 10.3899/jrheum.161473.


Comparison of systemic lupus erythematosus (SLE) patients managed early after diagnosis in specialty versus community care clinics.

Aljohani R, Gladman DD, Su J, Urowitz MB.

Clin Rheumatol. 2017 Aug;36(8):1773-1778. doi: 10.1007/s10067-017-3713-7. Epub 2017 Jun 6.


Psoriatic Arthritis.

Ritchlin CT, Colbert RA, Gladman DD.

N Engl J Med. 2017 May 25;376(21):2095-6. doi: 10.1056/NEJMc1704342. No abstract available.


Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.

Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT.

Nat Commun. 2017 May 24;8:15382. doi: 10.1038/ncomms15382.


Osteonecrosis in SLE: prevalence, patterns, outcomes and predictors.

Gladman DD, Dhillon N, Su J, Urowitz MB.

Lupus. 2018 Jan;27(1):76-81. doi: 10.1177/0961203317711012. Epub 2017 May 22.


Incidence and prevalence of psoriatic arthritis in Denmark: a nationwide register linkage study.

Egeberg A, Kristensen LE, Thyssen JP, Gislason GH, Gottlieb AB, Coates LC, Jullien D, Gisondi P, Gladman DD, Skov L, Mallbris L.

Ann Rheum Dis. 2017 Sep;76(9):1591-1597. doi: 10.1136/annrheumdis-2016-210963. Epub 2017 May 8.


Efficacy and safety of abatacept, a T-cell modulator, in a randomised, double-blind, placebo-controlled, phase III study in psoriatic arthritis.

Mease PJ, Gottlieb AB, van der Heijde D, FitzGerald O, Johnsen A, Nys M, Banerjee S, Gladman DD.

Ann Rheum Dis. 2017 Sep;76(9):1550-1558. doi: 10.1136/annrheumdis-2016-210724. Epub 2017 May 4.


Defining Outcome Measures for Psoriatic Arthritis: A Report from the GRAPPA-OMERACT Working Group.

Ogdie A, de Wit M, Callis Duffin K, Campbell W, Chau J, Coates LC, Eder L, Elmamoun M, FitzGerald O, Gladman DD, Goel N, James J, Kalyoncu U, Latella J, Lindsay C, Mease PJ, O'Sullivan D, Steinkoenig I, Strand V, Tillett W, Orbai AM.

J Rheumatol. 2017 May;44(5):697-700. doi: 10.3899/jrheum.170150.


Benchmarking Care in Psoriatic Arthritis - The QUANTUM Report: A Report from the GRAPPA 2016 Annual Meeting.

Favier G, Gladman DD, Merola JF, Armstrong AW, Boehncke WH, Helliwell PS.

J Rheumatol. 2017 May;44(5):674-678. doi: 10.3899/jrheum.170142.


Proceedings of the GRAPPA 2016 Retreat.

Jadon DR, Gladman DD, Mease PJ, FitzGerald O, Chandran V, Goel N, Rosen CF, Maksymowych WP, Ritchlin CT, Ogdie A, Coates LC, Cauli A, Soriano ER, Husni ME, Campbell W, Azevedo VF, Callis Duffin K, Armstrong AW, Gottlieb AB, Kavanaugh A, Garg A, Helliwell PS.

J Rheumatol. 2017 May;44(5):668-673. doi: 10.3899/jrheum.170141.


Prologue: 2016 Annual Meeting of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).

Helliwell PS, Gladman DD, Gottlieb AB.

J Rheumatol. 2017 May;44(5):658-660. doi: 10.3899/jrheum.170139.


Disease evolution in late-onset and early-onset systemic lupus erythematosus.

Aljohani R, Gladman DD, Su J, Urowitz MB.

Lupus. 2017 Oct;26(11):1190-1196. doi: 10.1177/0961203317696593. Epub 2017 Mar 12.


The prevalence and determinants of anti-DFS70 autoantibodies in an international inception cohort of systemic lupus erythematosus patients.

Choi MY, Clarke AE, St Pierre Y, Hanly JG, Urowitz MB, Romero-Diaz J, Gordon C, Bae SC, Bernatsky S, Wallace DJ, Merrill JT, Isenberg DA, Rahman A, Ginzler EM, Petri M, Bruce IN, Dooley MA, Fortin P, Gladman DD, Sanchez-Guerrero J, Steinsson K, Ramsey-Goldman R, Khamashta MA, Aranow C, Alarcón GS, Manzi S, Nived O, Zoma AA, van Vollenhoven RF, Ramos-Casals M, Ruiz-Irastorza G, Lim SS, Kalunian KC, Inanc M, Kamen DL, Peschken CA, Jacobsen S, Askanase A, Buyon J, Mahler M, Fritzler MJ.

Lupus. 2017 Sep;26(10):1051-1059. doi: 10.1177/0961203317692437. Epub 2017 Feb 23.


Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review & worked example using a clinic-based cohort of juvenile dermatomyositis patients.

Lim LS, Pullenayegum E, Moineddin R, Gladman DD, Silverman ED, Feldman BM.

Pediatr Rheumatol Online J. 2017 Mar 29;15(1):18. doi: 10.1186/s12969-017-0148-2. Review.


Psoriatic Arthritis.

Ritchlin CT, Colbert RA, Gladman DD.

N Engl J Med. 2017 Mar 9;376(10):957-970. doi: 10.1056/NEJMra1505557. Review. No abstract available. Erratum in: N Engl J Med. 2017 May 25;376(21):2097.


The Association Between Obesity and Clinical Features of Psoriatic Arthritis: A Case-control Study.

Eder L, Abji F, Rosen CF, Chandran V, Gladman DD.

J Rheumatol. 2017 Apr;44(4):437-443. doi: 10.3899/jrheum.160532. Epub 2017 Feb 15.


Prevalence and associated factors of resting electrocardiogram abnormalities among systemic lupus erythematosus patients without cardiovascular disease.

Al Rayes H, Harvey PJ, Gladman DD, Su J, Sabapathy A, Urowitz MB, Touma Z.

Arthritis Res Ther. 2017 Feb 10;19(1):31. doi: 10.1186/s13075-017-1240-1.


Psoriasis in systemic lupus erythematosus: a single-center experience.

Tselios K, Yap KS, Pakchotanon R, Polachek A, Su J, Urowitz MB, Gladman DD.

Clin Rheumatol. 2017 Apr;36(4):879-884. doi: 10.1007/s10067-017-3566-0. Epub 2017 Feb 6.


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