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Items: 7

1.

SYK is a candidate kinase target for the treatment of advanced prostate cancer.

Ghotra VP, He S, van der Horst G, Nijhoff S, de Bont H, Lekkerkerker A, Janssen R, Jenster G, van Leenders GJ, Hoogland AM, Verhoef EI, Baranski Z, Xiong J, van de Water B, van der Pluijm G, Snaar-Jagalska BE, Danen EH.

Cancer Res. 2015 Jan 1;75(1):230-40. doi: 10.1158/0008-5472.CAN-14-0629. Epub 2014 Nov 11.

2.

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

Truong HH, Xiong J, Ghotra VP, Nirmala E, Haazen L, Le Dévédec SE, Balcioğlu HE, He S, Snaar-Jagalska BE, Vreugdenhil E, Meerman JH, van de Water B, Danen EH.

Sci Signal. 2014 Feb 11;7(312):ra15. doi: 10.1126/scisignal.2004751.

PMID:
24518294
3.

Targeted radiosensitization in prostate cancer.

Ghotra VP, Geldof AA, Danen EH.

Curr Pharm Des. 2013;19(15):2819-28. Review.

PMID:
23448469
4.

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.

He S, Lamers GE, Beenakker JW, Cui C, Ghotra VP, Danen EH, Meijer AH, Spaink HP, Snaar-Jagalska BE.

J Pathol. 2012 Aug;227(4):431-45. doi: 10.1002/path.4013. Epub 2012 Jul 3.

5.

Automated whole animal bio-imaging assay for human cancer dissemination.

Ghotra VP, He S, de Bont H, van der Ent W, Spaink HP, van de Water B, Snaar-Jagalska BE, Danen EH.

PLoS One. 2012;7(2):e31281. doi: 10.1371/journal.pone.0031281. Epub 2012 Feb 8.

6.

Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens.

Truong HH, de Sonneville J, Ghotra VP, Xiong J, Price L, Hogendoorn PC, Spaink HH, van de Water B, Danen EH.

Biomaterials. 2012 Jan;33(1):181-8. doi: 10.1016/j.biomaterials.2011.09.049. Epub 2011 Oct 20.

PMID:
22018386
7.

The cancer stem cell microenvironment and anti-cancer therapy.

Ghotra VP, Puigvert JC, Danen EH.

Int J Radiat Biol. 2009 Nov;85(11):955-62. doi: 10.3109/09553000903242164. Review.

PMID:
19895272

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