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Items: 47

1.

The actin-binding protein profilin 2 is a novel regulator of iron homeostasis.

Luscieti S, Galy B, Gutierrez L, Reinke M, Couso J, Shvartsman M, Di Pascale A, Witke W, Hentze MW, Pilo Boyl P, Sanchez M.

Blood. 2017 Oct 26;130(17):1934-1945. doi: 10.1182/blood-2016-11-754382. Epub 2017 Aug 3.

PMID:
28774878
2.

Horizontal lifelines - review of regulations and simple design method considering anchorage rigidity.

Galy B, Lan A.

Int J Occup Saf Ergon. 2018 Mar;24(1):135-148. doi: 10.1080/10803548.2017.1300444. Epub 2017 Mar 28.

PMID:
28278004
3.

A Red Carpet for Iron Metabolism.

Muckenthaler MU, Rivella S, Hentze MW, Galy B.

Cell. 2017 Jan 26;168(3):344-361. doi: 10.1016/j.cell.2016.12.034. Review.

4.

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T.

Eur Heart J. 2017 Feb 1;38(5):362-372. doi: 10.1093/eurheartj/ehw333.

PMID:
27545647
5.

Ferritin-Mediated Iron Sequestration Stabilizes Hypoxia-Inducible Factor-1α upon LPS Activation in the Presence of Ample Oxygen.

Siegert I, Schödel J, Nairz M, Schatz V, Dettmer K, Dick C, Kalucka J, Franke K, Ehrenschwender M, Schley G, Beneke A, Sutter J, Moll M, Hellerbrand C, Wielockx B, Katschinski DM, Lang R, Galy B, Hentze MW, Koivunen P, Oefner PJ, Bogdan C, Weiss G, Willam C, Jantsch J.

Cell Rep. 2015 Dec 15;13(10):2048-55. doi: 10.1016/j.celrep.2015.11.005. Epub 2015 Nov 25.

6.

Mice with hepcidin-resistant ferroportin accumulate iron in the retina.

Theurl M, Song D, Clark E, Sterling J, Grieco S, Altamura S, Galy B, Hentze M, Muckenthaler MU, Dunaief JL.

FASEB J. 2016 Feb;30(2):813-23. doi: 10.1096/fj.15-276758. Epub 2015 Oct 27.

7.

Iron Regulatory Proteins Mediate Host Resistance to Salmonella Infection.

Nairz M, Ferring-Appel D, Casarrubea D, Sonnweber T, Viatte L, Schroll A, Haschka D, Fang FC, Hentze MW, Weiss G, Galy B.

Cell Host Microbe. 2015 Aug 12;18(2):254-61. doi: 10.1016/j.chom.2015.06.017. Epub 2015 Jul 16.

8.

A novel inflammatory pathway mediating rapid hepcidin-independent hypoferremia.

Guida C, Altamura S, Klein FA, Galy B, Boutros M, Ulmer AJ, Hentze MW, Muckenthaler MU.

Blood. 2015 Apr 2;125(14):2265-75. doi: 10.1182/blood-2014-08-595256. Epub 2015 Feb 6.

9.

Iron regulatory protein 1 sustains mitochondrial iron loading and function in frataxin deficiency.

Martelli A, Schmucker S, Reutenauer L, Mathieu JRR, Peyssonnaux C, Karim Z, Puy H, Galy B, Hentze MW, Puccio H.

Cell Metab. 2015 Feb 3;21(2):311-323. doi: 10.1016/j.cmet.2015.01.010.

10.

Resistance of ferroportin to hepcidin binding causes exocrine pancreatic failure and fatal iron overload.

Altamura S, Kessler R, Gröne HJ, Gretz N, Hentze MW, Galy B, Muckenthaler MU.

Cell Metab. 2014 Aug 5;20(2):359-67. doi: 10.1016/j.cmet.2014.07.007.

11.

Iron regulatory protein-1 protects against mitoferrin-1-deficient porphyria.

Chung J, Anderson SA, Gwynn B, Deck KM, Chen MJ, Langer NB, Shaw GC, Huston NC, Boyer LF, Datta S, Paradkar PN, Li L, Wei Z, Lambert AJ, Sahr K, Wittig JG, Chen W, Lu W, Galy B, Schlaeger TM, Hentze MW, Ward DM, Kaplan J, Eisenstein RS, Peters LL, Paw BH.

J Biol Chem. 2014 Mar 14;289(11):7835-43. doi: 10.1074/jbc.M114.547778. Epub 2014 Feb 7. Erratum in: J Biol Chem. 2014 May 16;289(20):13707.

12.

Iron regulatory proteins control a mucosal block to intestinal iron absorption.

Galy B, Ferring-Appel D, Becker C, Gretz N, Gröne HJ, Schümann K, Hentze MW.

Cell Rep. 2013 Mar 28;3(3):844-57. doi: 10.1016/j.celrep.2013.02.026. Epub 2013 Mar 21.

13.

Abnormal body iron distribution and erythropoiesis in a novel mouse model with inducible gain of iron regulatory protein (IRP)-1 function.

Casarrubea D, Viatte L, Hallas T, Vasanthakumar A, Eisenstein RS, Schümann K, Hentze MW, Galy B.

J Mol Med (Berl). 2013 Jul;91(7):871-81. doi: 10.1007/s00109-013-1008-2. Epub 2013 Mar 1.

14.

The IRP1-HIF-2α axis coordinates iron and oxygen sensing with erythropoiesis and iron absorption.

Anderson SA, Nizzi CP, Chang YI, Deck KM, Schmidt PJ, Galy B, Damnernsawad A, Broman AT, Kendziorski C, Hentze MW, Fleming MD, Zhang J, Eisenstein RS.

Cell Metab. 2013 Feb 5;17(2):282-90. doi: 10.1016/j.cmet.2013.01.007.

15.

Iron regulatory protein-1 and -2: transcriptome-wide definition of binding mRNAs and shaping of the cellular proteome by iron regulatory proteins.

Sanchez M, Galy B, Schwanhaeusser B, Blake J, Bähr-Ivacevic T, Benes V, Selbach M, Muckenthaler MU, Hentze MW.

Blood. 2011 Nov 24;118(22):e168-79. doi: 10.1182/blood-2011-04-343541. Epub 2011 Sep 22.

16.

Iron regulatory protein 1 outcompetes iron regulatory protein 2 in regulating cellular iron homeostasis in response to nitric oxide.

Styś A, Galy B, Starzyński RR, Smuda E, Drapier JC, Lipiński P, Bouton C.

J Biol Chem. 2011 Jul 1;286(26):22846-54. doi: 10.1074/jbc.M111.231902. Epub 2011 May 12.

17.

Iron regulatory proteins secure mitochondrial iron sufficiency and function.

Galy B, Ferring-Appel D, Sauer SW, Kaden S, Lyoumi S, Puy H, Kölker S, Gröne HJ, Hentze MW.

Cell Metab. 2010 Aug 4;12(2):194-201. doi: 10.1016/j.cmet.2010.06.007.

18.

Two to tango: regulation of Mammalian iron metabolism.

Hentze MW, Muckenthaler MU, Galy B, Camaschella C.

Cell. 2010 Jul 9;142(1):24-38. doi: 10.1016/j.cell.2010.06.028. Review.

19.

Serum ferritin is derived primarily from macrophages through a nonclassical secretory pathway.

Cohen LA, Gutierrez L, Weiss A, Leichtmann-Bardoogo Y, Zhang DL, Crooks DR, Sougrat R, Morgenstern A, Galy B, Hentze MW, Lazaro FJ, Rouault TA, Meyron-Holtz EG.

Blood. 2010 Sep 2;116(9):1574-84. doi: 10.1182/blood-2009-11-253815. Epub 2010 May 14.

20.

In vivo role(s) of the iron regulatory proteins (IRP) 1 and 2 in aseptic local inflammation.

Viatte L, Gröne HJ, Hentze MW, Galy B.

J Mol Med (Berl). 2009 Sep;87(9):913-21. doi: 10.1007/s00109-009-0494-8. Epub 2009 Jun 17.

PMID:
19533074
21.

Cell-autonomous and systemic context-dependent functions of iron regulatory protein 2 in mammalian iron metabolism.

Ferring-Appel D, Hentze MW, Galy B.

Blood. 2009 Jan 15;113(3):679-87. doi: 10.1182/blood-2008-05-155093. Epub 2008 Oct 15.

22.

Systemic iron homeostasis and the iron-responsive element/iron-regulatory protein (IRE/IRP) regulatory network.

Muckenthaler MU, Galy B, Hentze MW.

Annu Rev Nutr. 2008;28:197-213. doi: 10.1146/annurev.nutr.28.061807.155521. Review.

PMID:
18489257
23.

Hfe acts in hepatocytes to prevent hemochromatosis.

Vujić Spasić M, Kiss J, Herrmann T, Galy B, Martinache S, Stolte J, Gröne HJ, Stremmel W, Hentze MW, Muckenthaler MU.

Cell Metab. 2008 Feb;7(2):173-8. doi: 10.1016/j.cmet.2007.11.014.

24.

Iron regulatory proteins are essential for intestinal function and control key iron absorption molecules in the duodenum.

Galy B, Ferring-Appel D, Kaden S, Gröne HJ, Hentze MW.

Cell Metab. 2008 Jan;7(1):79-85. doi: 10.1016/j.cmet.2007.10.006.

25.

Identification of target mRNAs of regulatory RNA-binding proteins using mRNP immunopurification and microarrays.

Sanchez M, Galy B, Hentze MW, Muckenthaler MU.

Nat Protoc. 2007;2(8):2033-42.

PMID:
17703216
26.

Iron-regulatory proteins limit hypoxia-inducible factor-2alpha expression in iron deficiency.

Sanchez M, Galy B, Muckenthaler MU, Hentze MW.

Nat Struct Mol Biol. 2007 May;14(5):420-6. Epub 2007 Apr 8.

PMID:
17417656
27.

Physiologic systemic iron metabolism in mice deficient for duodenal Hfe.

Vujic Spasic M, Kiss J, Herrmann T, Kessler R, Stolte J, Galy B, Rathkolb B, Wolf E, Stremmel W, Hentze MW, Muckenthaler MU.

Blood. 2007 May 15;109(10):4511-7. Epub 2007 Jan 30.

28.

Iron homeostasis in the brain: complete iron regulatory protein 2 deficiency without symptomatic neurodegeneration in the mouse.

Galy B, Hölter SM, Klopstock T, Ferring D, Becker L, Kaden S, Wurst W, Gröne HJ, Hentze MW.

Nat Genet. 2006 Sep;38(9):967-9; discussion 969-70. No abstract available.

PMID:
16940998
29.

IRP1-independent alterations of cardiac iron metabolism in doxorubicin-treated mice.

Corna G, Galy B, Hentze MW, Cairo G.

J Mol Med (Berl). 2006 Jul;84(7):551-60. Epub 2006 Jun 13.

PMID:
16770644
30.

Iron regulation and the cell cycle: identification of an iron-responsive element in the 3'-untranslated region of human cell division cycle 14A mRNA by a refined microarray-based screening strategy.

Sanchez M, Galy B, Dandekar T, Bengert P, Vainshtein Y, Stolte J, Muckenthaler MU, Hentze MW.

J Biol Chem. 2006 Aug 11;281(32):22865-74. Epub 2006 Jun 7.

31.

Generation of conditional alleles of the murine Iron Regulatory Protein (IRP)-1 and -2 genes.

Galy B, Ferring D, Hentze MW.

Genesis. 2005 Dec;43(4):181-8.

PMID:
16283625
32.

Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2).

Galy B, Ferring D, Minana B, Bell O, Janser HG, Muckenthaler M, Schümann K, Hentze MW.

Blood. 2005 Oct 1;106(7):2580-9. Epub 2005 Jun 14.

33.

Enhancement of IRES-mediated translation of the c-myc and BiP mRNAs by the poly(A) tail is independent of intact eIF4G and PABP.

Thoma C, Bergamini G, Galy B, Hundsdoerfer P, Hentze MW.

Mol Cell. 2004 Sep 24;15(6):925-35.

34.
35.

Iron-mediated degradation of IRP2, an unexpected pathway involving a 2-oxoglutarate-dependent oxygenase activity.

Wang J, Chen G, Muckenthaler M, Galy B, Hentze MW, Pantopoulos K.

Mol Cell Biol. 2004 Feb;24(3):954-65.

36.

Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites.

Vagner S, Galy B, Pyronnet S.

EMBO Rep. 2001 Oct;2(10):893-8. Review.

37.

Hereditary haemochromatosis: more causative genes.

Galy B.

Trends Mol Med. 2001 Sep;7(9):385. No abstract available.

PMID:
11530320
38.

Hereditary haemochromatosis: more causative genes.

Galy B.

Trends Biochem Sci. 2001 Aug;26(8):473. No abstract available.

PMID:
11504616
39.

p53 directs conformational change and translation initiation blockade of human fibroblast growth factor 2 mRNA.

Galy B, Créancier L, Prado-Lourenço L, Prats AC, Prats H.

Oncogene. 2001 Aug 2;20(34):4613-20.

40.

Tumour suppressor p53 inhibits human fibroblast growth factor 2 expression by a post-transcriptional mechanism.

Galy B, Créancier L, Zanibellato C, Prats AC, Prats H.

Oncogene. 2001 Mar 29;20(14):1669-77.

41.

Translational control and synaptic activity: a role for IRES elements?

Galy B.

Trends Biochem Sci. 2001 Apr;26(4):220. No abstract available.

PMID:
11295546
42.

Extracellular iron: a signal that can be sensed and transduced in bacteria.

Galy B.

Trends Biochem Sci. 2000 Dec;25(12):643-4. No abstract available.

PMID:
11116193
43.

IRES elements: fine-tuning of gene expression at the translational level.

Galy B.

Trends Biochem Sci. 2000 Sep;25(9):426. No abstract available.

PMID:
10986454
44.

Hepatocellular hypoxia-induced vascular endothelial growth factor expression and angiogenesis in experimental biliary cirrhosis.

Rosmorduc O, Wendum D, Corpechot C, Galy B, Sebbagh N, Raleigh J, Housset C, Poupon R.

Am J Pathol. 1999 Oct;155(4):1065-73.

46.

Translation of CUG- but not AUG-initiated forms of human fibroblast growth factor 2 is activated in transformed and stressed cells.

Vagner S, Touriol C, Galy B, Audigier S, Gensac MC, Amalric F, Bayard F, Prats H, Prats AC.

J Cell Biol. 1996 Dec;135(5):1391-402.

47.

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