Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 14

1.

G protein stoichiometry dictates biased agonism through distinct receptor-G protein partitioning.

Onfroy L, Galandrin S, Pontier SM, Seguelas MH, N'Guyen D, Sénard JM, Galés C.

Sci Rep. 2017 Aug 11;7(1):7885. doi: 10.1038/s41598-017-07392-5.

2.

Cardioprotective Angiotensin-(1-7) Peptide Acts as a Natural-Biased Ligand at the Angiotensin II Type 1 Receptor.

Galandrin S, Denis C, Boularan C, Marie J, M'Kadmi C, Pilette C, Dubroca C, Nicaise Y, Seguelas MH, N'Guyen D, Banères JL, Pathak A, Sénard JM, Galés C.

Hypertension. 2016 Dec;68(6):1365-1374. Epub 2016 Oct 3.

3.

Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis.

Le NH, Molle V, Eynard N, Miras M, Stella A, Bardou F, Galandrin S, Guillet V, André-Leroux G, Bellinzoni M, Alzari P, Mourey L, Burlet-Schiltz O, Daffé M, Marrakchi H.

J Biol Chem. 2016 Oct 21;291(43):22793-22805. Epub 2016 Sep 2.

4.

Delineating biased ligand efficacy at 7TM receptors from an experimental perspective.

Galandrin S, Onfroy L, Poirot MC, Sénard JM, Galés C.

Int J Biochem Cell Biol. 2016 Aug;77(Pt B):251-63. doi: 10.1016/j.biocel.2016.04.009. Epub 2016 Apr 21. Review.

PMID:
27107932
5.

Insight into Structure-Function Relationships and Inhibition of the Fatty Acyl-AMP Ligase (FadD32) Orthologs from Mycobacteria.

Guillet V, Galandrin S, Maveyraud L, Ladevèze S, Mariaule V, Bon C, Eynard N, Daffé M, Marrakchi H, Mourey L.

J Biol Chem. 2016 Apr 8;291(15):7973-89. doi: 10.1074/jbc.M115.712612. Epub 2016 Feb 21.

6.

The experimental power of FR900359 to study Gq-regulated biological processes.

Schrage R, Schmitz AL, Gaffal E, Annala S, Kehraus S, Wenzel D, Büllesbach KM, Bald T, Inoue A, Shinjo Y, Galandrin S, Shridhar N, Hesse M, Grundmann M, Merten N, Charpentier TH, Martz M, Butcher AJ, Slodczyk T, Armando S, Effern M, Namkung Y, Jenkins L, Horn V, Stößel A, Dargatz H, Tietze D, Imhof D, Galés C, Drewke C, Müller CE, Hölzel M, Milligan G, Tobin AB, Gomeza J, Dohlman HG, Sondek J, Harden TK, Bouvier M, Laporte SA, Aoki J, Fleischmann BK, Mohr K, König GM, Tüting T, Kostenis E.

Nat Commun. 2015 Dec 14;6:10156. doi: 10.1038/ncomms10156.

7.

Dual agonist occupancy of AT1-R-α2C-AR heterodimers results in atypical Gs-PKA signaling.

Bellot M, Galandrin S, Boularan C, Matthies HJ, Despas F, Denis C, Javitch J, Mazères S, Sanni SJ, Pons V, Seguelas MH, Hansen JL, Pathak A, Galli A, Sénard JM, Galés C.

Nat Chem Biol. 2015 Apr;11(4):271-9. doi: 10.1038/nchembio.1766. Epub 2015 Feb 23.

8.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.

Damian M, Mary S, Maingot M, M'Kadmi C, Gagne D, Leyris JP, Denoyelle S, Gaibelet G, Gavara L, Garcia de Souza Costa M, Perahia D, Trinquet E, Mouillac B, Galandrin S, Galès C, Fehrentz JA, Floquet N, Martinez J, Marie J, Banères JL.

Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):1601-6. doi: 10.1073/pnas.1414618112. Epub 2015 Jan 20.

9.

Assay development for identifying inhibitors of the mycobacterial FadD32 activity.

Galandrin S, Guillet V, Rane RS, Léger M, N R, Eynard N, Das K, Balganesh TS, Mourey L, Daffé M, Marrakchi H.

J Biomol Screen. 2013 Jun;18(5):576-87. doi: 10.1177/1087057112474691. Epub 2013 Jan 30.

PMID:
23364516
10.

Probing heterotrimeric G protein activation: applications to biased ligands.

Denis C, Saulière A, Galandrin S, Sénard JM, Galés C.

Curr Pharm Des. 2012;18(2):128-44. Review.

11.

Cholesterol-dependent separation of the beta2-adrenergic receptor from its partners determines signaling efficacy: insight into nanoscale organization of signal transduction.

Pontier SM, Percherancier Y, Galandrin S, Breit A, Galés C, Bouvier M.

J Biol Chem. 2008 Sep 5;283(36):24659-72. doi: 10.1074/jbc.M800778200. Epub 2008 Jun 19.

12.

Conformational rearrangements and signaling cascades involved in ligand-biased mitogen-activated protein kinase signaling through the beta1-adrenergic receptor.

Galandrin S, Oligny-Longpré G, Bonin H, Ogawa K, Galés C, Bouvier M.

Mol Pharmacol. 2008 Jul;74(1):162-72. doi: 10.1124/mol.107.043893. Epub 2008 Apr 10.

13.

The evasive nature of drug efficacy: implications for drug discovery.

Galandrin S, Oligny-Longpré G, Bouvier M.

Trends Pharmacol Sci. 2007 Aug;28(8):423-30. Epub 2007 Jul 19. Review.

PMID:
17659355

Supplemental Content

Loading ...
Support Center