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Items: 1 to 50 of 104

1.

An increase in LRRK2 suppresses autophagy and enhances Dectin-1-induced immunity in a mouse model of colitis.

Takagawa T, Kitani A, Fuss I, Levine B, Brant SR, Peter I, Tajima M, Nakamura S, Strober W.

Sci Transl Med. 2018 Jun 6;10(444). pii: eaan8162. doi: 10.1126/scitranslmed.aan8162.

PMID:
29875204
2.

Loss-of-function CARD8 mutation causes NLRP3 inflammasome activation and Crohn's disease.

Mao L, Kitani A, Similuk M, Oler AJ, Albenberg L, Kelsen J, Aktay A, Quezado M, Yao M, Montgomery-Recht K, Fuss IJ, Strober W.

J Clin Invest. 2018 May 1;128(5):1793-1806. doi: 10.1172/JCI98642. Epub 2018 Mar 26.

3.

Tumor growth limited to subcutaneous site vs tumor growth in pulmonary site exhibit differential effects on systemic immunities.

Masuda J, Takayama E, Strober W, Satoh A, Morimoto Y, Honjo Y, Ichinohe T, Tokuno SI, Ishizuka T, Nakata T, Mizutani A, Umemura N, Kitani A, Fuss IJ, Shigehiro T, Kawaki H, Mizuno-Kamiya M, Kondoh N, Seno M.

Oncol Rep. 2017 Jul;38(1):449-455. doi: 10.3892/or.2017.5646. Epub 2017 May 17.

PMID:
28535011
4.

BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency.

Afzali B, Grönholm J, Vandrovcova J, O'Brien C, Sun HW, Vanderleyden I, Davis FP, Khoder A, Zhang Y, Hegazy AN, Villarino AV, Palmer IW, Kaufman J, Watts NR, Kazemian M, Kamenyeva O, Keith J, Sayed A, Kasperaviciute D, Mueller M, Hughes JD, Fuss IJ, Sadiyah MF, Montgomery-Recht K, McElwee J, Restifo NP, Strober W, Linterman MA, Wingfield PT, Uhlig HH, Roychoudhuri R, Aitman TJ, Kelleher P, Lenardo MJ, O'Shea JJ, Cooper N, Laurence ADJ.

Nat Immunol. 2017 Jul;18(7):813-823. doi: 10.1038/ni.3753. Epub 2017 May 22.

5.

Akkermansia muciniphila mediates negative effects of IFNγ on glucose metabolism.

Greer RL, Dong X, Moraes AC, Zielke RA, Fernandes GR, Peremyslova E, Vasquez-Perez S, Schoenborn AA, Gomes EP, Pereira AC, Ferreira SR, Yao M, Fuss IJ, Strober W, Sikora AE, Taylor GA, Gulati AS, Morgun A, Shulzhenko N.

Nat Commun. 2016 Nov 14;7:13329. doi: 10.1038/ncomms13329.

6.

Ataxia telangiectasia associated with nodular regenerative hyperplasia.

Milligan KL, Schirm K, Leonard S, Hussey AA, Agharahimi A, Kleiner DE, Fuss I, Lingala S, Heller T, Rosenzweig SD.

J Clin Immunol. 2016 Nov;36(8):739-742. Epub 2016 Sep 26. No abstract available.

7.

Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting.

Masuda J, Kawamoto H, Strober W, Takayama E, Mizutani A, Murakami H, Ikawa T, Kitani A, Maeno N, Shigehiro T, Satoh A, Seno A, Arun V, Kasai T, Fuss IJ, Katsura Y, Seno M.

Appl Biochem Biotechnol. 2016 Dec;180(8):1559-1573. Epub 2016 Jul 12.

PMID:
27406037
8.

Experimental Models of Inflammatory Bowel Diseases.

Kiesler P, Fuss IJ, Strober W.

Cell Mol Gastroenterol Hepatol. 2015 Mar 1;1(2):154-170.

9.

Dynamic changes in E-protein activity regulate T reg cell development.

Gao P, Han X, Zhang Q, Yang Z, Fuss IJ, Myers TG, Gardina PJ, Zhang F, Strober W.

J Exp Med. 2014 Dec 15;211(13):2651-68. doi: 10.1084/jem.20132681. Epub 2014 Dec 8.

10.

Cellular and molecular mechanisms underlying NOD2 risk-associated polymorphisms in Crohn's disease.

Strober W, Asano N, Fuss I, Kitani A, Watanabe T.

Immunol Rev. 2014 Jul;260(1):249-60. doi: 10.1111/imr.12193. Review.

PMID:
24942694
11.

NOD2 downregulates colonic inflammation by IRF4-mediated inhibition of K63-linked polyubiquitination of RICK and TRAF6.

Watanabe T, Asano N, Meng G, Yamashita K, Arai Y, Sakurai T, Kudo M, Fuss IJ, Kitani A, Shimosegawa T, Chiba T, Strober W.

Mucosal Immunol. 2014 Nov;7(6):1312-25. doi: 10.1038/mi.2014.19. Epub 2014 Mar 26.

12.

IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis.

Fuss IJ, Joshi B, Yang Z, Degheidy H, Fichtner-Feigl S, de Souza H, Rieder F, Scaldaferri F, Schirbel A, Scarpa M, West G, Yi C, Xu L, Leland P, Yao M, Mannon P, Puri RK, Fiocchi C, Strober W.

Gut. 2014 Nov;63(11):1728-36. doi: 10.1136/gutjnl-2013-305671. Epub 2014 Feb 10.

13.

Transcription of RORγt in developing Th17 cells is regulated by E-proteins.

Zhang F, Fuss IJ, Yang Z, Strober W.

Mucosal Immunol. 2014 May;7(3):521-32. doi: 10.1038/mi.2013.69. Epub 2013 Sep 25.

14.

Open parallel cooperative and competitive decision processes: a potential provenance for quantum probability decision models.

Fuss IG, Navarro DJ.

Top Cogn Sci. 2013 Oct;5(4):818-43. doi: 10.1111/tops.12045. Epub 2013 Sep 9.

15.

Pregnancy-specific glycoprotein 1 (PSG1) activates TGF-β and prevents dextran sodium sulfate (DSS)-induced colitis in mice.

Blois SM, Sulkowski G, Tirado-González I, Warren J, Freitag N, Klapp BF, Rifkin D, Fuss I, Strober W, Dveksler GS.

Mucosal Immunol. 2014 Mar;7(2):348-58. doi: 10.1038/mi.2013.53. Epub 2013 Aug 14.

16.

Prognostic factors for pain relief and functional improvement in chronic pain after inpatient rehabilitation.

Fuss I, Angst F, Lehmann S, Michel BA, Aeschlimann A.

Clin J Pain. 2014 Apr;30(4):279-85. doi: 10.1097/AJP.0b013e31829a4d11.

17.

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection.

Grainger JR, Wohlfert EA, Fuss IJ, Bouladoux N, Askenase MH, Legrand F, Koo LY, Brenchley JM, Fraser ID, Belkaid Y.

Nat Med. 2013 Jun;19(6):713-21. doi: 10.1038/nm.3189. Epub 2013 May 26.

18.

What are the mechanics of quantum cognition?

Navarro DJ, Fuss I.

Behav Brain Sci. 2013 Jun;36(3):299-300. doi: 10.1017/S0140525X12003056.

PMID:
23673046
19.

Nodular regenerative hyperplasia in common variable immunodeficiency.

Fuss IJ, Friend J, Yang Z, He JP, Hooda L, Boyer J, Xi L, Raffeld M, Kleiner DE, Heller T, Strober W.

J Clin Immunol. 2013 May;33(4):748-58. doi: 10.1007/s10875-013-9873-6. Epub 2013 Feb 19.

20.

The deubiquitinase CYLD targets Smad7 protein to regulate transforming growth factor β (TGF-β) signaling and the development of regulatory T cells.

Zhao Y, Thornton AM, Kinney MC, Ma CA, Spinner JJ, Fuss IJ, Shevach EM, Jain A.

J Biol Chem. 2011 Nov 25;286(47):40520-30. doi: 10.1074/jbc.M111.292961. Epub 2011 Sep 19.

21.

Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases.

Strober W, Fuss IJ.

Gastroenterology. 2011 May;140(6):1756-1767. doi: 10.1053/j.gastro.2011.02.016. Review.

22.

Tumor development in murine ulcerative colitis depends on MyD88 signaling of colonic F4/80+CD11b(high)Gr1(low) macrophages.

Schiechl G, Bauer B, Fuss I, Lang SA, Moser C, Ruemmele P, Rose-John S, Neurath MF, Geissler EK, Schlitt HJ, Strober W, Fichtner-Feigl S.

J Clin Invest. 2011 May;121(5):1692-708. doi: 10.1172/JCI42540. Epub 2011 Apr 25.

23.

A polymorphism in the coding region of Il12b promotes IL-12p70 and IL-23 heterodimer formation.

Zwiers A, Fuss IJ, Seegers D, Konijn T, Garcia-Vallejo JJ, Samsom JN, Strober W, Kraal G, Bouma G.

J Immunol. 2011 Mar 15;186(6):3572-80. doi: 10.4049/jimmunol.1001330. Epub 2011 Feb 14.

24.

NOD1-Mediated Mucosal Host Defense against Helicobacter pylori.

Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober W.

Int J Inflam. 2010 Jul 15;2010:476482. doi: 10.4061/2010/476482.

25.

The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation.

Meylan F, Song YJ, Fuss I, Villarreal S, Kahle E, Malm IJ, Acharya K, Ramos HL, Lo L, Mentink-Kane MM, Wynn TA, Migone TS, Strober W, Siegel RM.

Mucosal Immunol. 2011 Mar;4(2):172-85. doi: 10.1038/mi.2010.67. Epub 2010 Oct 27.

26.

Suppression of inflammation in ulcerative colitis by interferon-β-1a is accompanied by inhibition of IL-13 production.

Mannon PJ, Hornung RL, Yang Z, Yi C, Groden C, Friend J, Yao M, Strober W, Fuss IJ.

Gut. 2011 Apr;60(4):449-55. doi: 10.1136/gut.2010.226860. Epub 2010 Oct 22.

27.

Positive and negative transcriptional regulation of the Foxp3 gene is mediated by access and binding of the Smad3 protein to enhancer I.

Xu L, Kitani A, Stuelten C, McGrady G, Fuss I, Strober W.

Immunity. 2010 Sep 24;33(3):313-25. doi: 10.1016/j.immuni.2010.09.001.

28.

Proinflammatory cytokines underlying the inflammation of Crohn's disease.

Strober W, Zhang F, Kitani A, Fuss I, Fichtner-Feigl S.

Curr Opin Gastroenterol. 2010 Jul;26(4):310-7. doi: 10.1097/MOG.0b013e328339d099.

29.

[Topical anesthesia before vascular access in children. Comparison of a warmth-producing lidocaine-tetracaine patch with a lidocaine-prilocaine patch].

Soltesz S, Dittrich K, Teschendorf P, Fuss I, Molter G.

Anaesthesist. 2010 Jun;59(6):519-23. doi: 10.1007/s00101-010-1727-5. German.

PMID:
20458453
30.

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.

Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W.

J Clin Invest. 2010 May;120(5):1645-62. doi: 10.1172/JCI39481. Epub 2010 Apr 12.

31.

Activation of type I IFN signaling by NOD1 mediates mucosal host defense against Helicobacter pylori infection.

Watanabe T, Asano N, Kitani A, Fuss IJ, Chiba T, Strober W.

Gut Microbes. 2011 Jan-Feb;2(1):61-5. doi: 10.4161/gmic.2.1.15162. Review.

32.

The signaling function of the IL-13Ralpha2 receptor in the development of gastrointestinal fibrosis and cancer surveillance.

Strober W, Kitani A, Fichtner-Feigl S, Fuss IJ.

Curr Mol Med. 2009 Aug;9(6):740-50. Review.

PMID:
19689301
33.

A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses.

Meng G, Zhang F, Fuss I, Kitani A, Strober W.

Immunity. 2009 Jun 19;30(6):860-74. doi: 10.1016/j.immuni.2009.04.012. Epub 2009 Jun 4.

34.

Isolation of whole mononuclear cells from peripheral blood and cord blood.

Fuss IJ, Kanof ME, Smith PD, Zola H.

Curr Protoc Immunol. 2009 Apr;Chapter 7:Unit7.1. doi: 10.1002/0471142735.im0701s85.

PMID:
19347849
35.

The molecular basis of NOD2 susceptibility mutations in Crohn's disease.

Strober W, Kitani A, Fuss I, Asano N, Watanabe T.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S5-9. doi: 10.1038/mi.2008.42. Review.

36.

The role of IL-13 and NK T cells in experimental and human ulcerative colitis.

Fuss IJ, Strober W.

Mucosal Immunol. 2008 Nov;1 Suppl 1:S31-3. doi: 10.1038/mi.2008.40. Review.

37.

Successful granulocyte-colony stimulating factor treatment of Crohn's disease is associated with the appearance of circulating interleukin-10-producing T cells and increased lamina propria plasmacytoid dendritic cells.

Mannon PJ, Leon F, Fuss IJ, Walter BA, Begnami M, Quezado M, Yang Z, Yi C, Groden C, Friend J, Hornung RL, Brown M, Gurprasad S, Kelsall B, Strober W.

Clin Exp Immunol. 2009 Mar;155(3):447-56. doi: 10.1111/j.1365-2249.2008.03799.x. Epub 2008 Dec 15.

38.

Working conditions and Work-Family Conflict in German hospital physicians: psychosocial and organisational predictors and consequences.

Fuss I, Nübling M, Hasselhorn HM, Schwappach D, Rieger MA.

BMC Public Health. 2008 Oct 7;8:353. doi: 10.1186/1471-2458-8-353.

39.

Increased expression of the tight junction molecule claudin-18 A1 in both experimental colitis and ulcerative colitis.

Zwiers A, Fuss IJ, Leijen S, Mulder CJ, Kraal G, Bouma G.

Inflamm Bowel Dis. 2008 Dec;14(12):1652-9. doi: 10.1002/ibd.20695.

PMID:
18831034
40.

Is the Th1/Th2 paradigm of immune regulation applicable to IBD?

Fuss IJ.

Inflamm Bowel Dis. 2008 Oct;14 Suppl 2:S110-2. doi: 10.1002/ibd.20683. No abstract available. Erratum in: Inflamm Bowel Dis. 2009 Sep;15(9):1438-47.

PMID:
18816734
41.

A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis.

Boirivant M, Amendola A, Butera A, Sanchez M, Xu L, Marinaro M, Kitani A, Di Giacinto C, Strober W, Fuss IJ.

Gastroenterology. 2008 Nov;135(5):1612-1623.e5. doi: 10.1053/j.gastro.2008.07.028. Epub 2008 Aug 5.

PMID:
18765239
42.

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.

Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ.

Nature. 2008 Sep 11;455(7210):246-50. doi: 10.1038/nature07210.

43.

Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2.

Fichtner-Feigl S, Terabe M, Kitani A, Young CA, Fuss I, Geissler EK, Schlitt HJ, Berzofsky JA, Strober W.

Cancer Res. 2008 May 1;68(9):3467-75. doi: 10.1158/0008-5472.CAN-07-5301.

44.

Induction of TNBS colitis in mice.

Scheiffele F, Fuss IJ.

Curr Protoc Immunol. 2002 Aug;Chapter 15:Unit 15.19. doi: 10.1002/0471142735.im1519s49.

PMID:
18432874
45.

Notch1 signaling and regulatory T cell function.

Asano N, Watanabe T, Kitani A, Fuss IJ, Strober W.

J Immunol. 2008 Mar 1;180(5):2796-804.

46.

Muramyl dipeptide activation of nucleotide-binding oligomerization domain 2 protects mice from experimental colitis.

Watanabe T, Asano N, Murray PJ, Ozato K, Tailor P, Fuss IJ, Kitani A, Strober W.

J Clin Invest. 2008 Feb;118(2):545-59. doi: 10.1172/JCI33145.

47.

NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction.

Yang Z, Fuss IJ, Watanabe T, Asano N, Davey MP, Rosenbaum JT, Strober W, Kitani A.

Gastroenterology. 2007 Nov;133(5):1510-21. Epub 2007 Jul 25.

48.

Lymphocyte-dependent and Th2 cytokine-associated colitis in mice deficient in Wiskott-Aldrich syndrome protein.

Nguyen DD, Maillard MH, Cotta-de-Almeida V, Mizoguchi E, Klein C, Fuss I, Nagler C, Mizoguchi A, Bhan AK, Snapper SB.

Gastroenterology. 2007 Oct;133(4):1188-97. Epub 2007 Jul 12.

50.

Induction of IL-13 triggers TGF-beta1-dependent tissue fibrosis in chronic 2,4,6-trinitrobenzene sulfonic acid colitis.

Fichtner-Feigl S, Fuss IJ, Young CA, Watanabe T, Geissler EK, Schlitt HJ, Kitani A, Strober W.

J Immunol. 2007 May 1;178(9):5859-70.

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