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Items: 1 to 50 of 168

1.

Early onset of inflammation during ontogeny of bipolar disorder: the NLRP2 inflammasome gene distinctly differentiates between patients and healthy controls in the transition between iPS cell and neural stem cell stages.

Vizlin-Hodzic D, Zhai Q, Illes S, Södersten K, Truvé K, Parris TZ, Sobhan PK, Salmela S, Kosalai ST, Kanduri C, Strandberg J, Seth H, Bontell TO, Hanse E, Ågren H, Funa K.

Transl Psychiatry. 2017 Jan 24;7(1):e1010. doi: 10.1038/tp.2016.284.

2.

Comparison of the glycosphingolipids of human-induced pluripotent stem cells and human embryonic stem cells.

Säljö K, Barone A, Vizlin-Hodzic D, Johansson BR, Breimer ME, Funa K, Teneberg S.

Glycobiology. 2017 Apr 1;27(4):291-305. doi: 10.1093/glycob/cww125.

PMID:
27932383
3.

ASK1 regulates the survival of neuroblastoma cells by interacting with TLX and stabilizing HIF-1α.

Sobhan PK, Zhai Q, Green LC, Hansford LM, Funa K.

Cell Signal. 2017 Jan;30:104-117. doi: 10.1016/j.cellsig.2016.11.018. Epub 2016 Nov 24.

4.

Nuclear receptor TLX inhibits TGF-β signaling in glioblastoma.

Johansson E, Zhai Q, Zeng ZJ, Yoshida T, Funa K.

Exp Cell Res. 2016 May 1;343(2):118-125. doi: 10.1016/j.yexcr.2016.03.028. Epub 2016 Apr 2.

PMID:
27048878
5.

TLX-Its Emerging Role for Neurogenesis in Health and Disease.

Sobhan PK, Funa K.

Mol Neurobiol. 2017 Jan;54(1):272-280. doi: 10.1007/s12035-015-9608-1. Epub 2016 Jan 6. Review.

6.

Proteomics of dedifferentiation of SK-N-BE2 neuroblastoma cells.

Saini RK, Attarha S, da Silva Santos C, Kolakowska J, Funa K, Souchelnytskyi S.

Biochem Biophys Res Commun. 2014 Nov 7;454(1):202-9. doi: 10.1016/j.bbrc.2014.10.065. Epub 2014 Oct 18.

PMID:
25450381
7.

TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.

Chavali PL, Saini RK, Zhai Q, Vizlin-Hodzic D, Venkatabalasubramanian S, Hayashi A, Johansson E, Zeng ZJ, Mohlin S, Påhlman S, Hansford L, Kaplan DR, Funa K.

Cell Death Dis. 2014 Oct 30;5:e1502. doi: 10.1038/cddis.2014.449.

8.

Calcium-dependent intracellular signal pathways in primary cultured adipocytes and ANK3 gene variation in patients with bipolar disorder and healthy controls.

Hayashi A, Le Gal K, Södersten K, Vizlin-Hodzic D, Ågren H, Funa K.

Mol Psychiatry. 2015 Aug;20(8):931-40. doi: 10.1038/mp.2014.104. Epub 2014 Oct 14.

9.

Abnormality in serum levels of mature brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in mood-stabilized patients with bipolar disorder: a study of two independent cohorts.

Södersten K, Pålsson E, Ishima T, Funa K, Landén M, Hashimoto K, Ågren H.

J Affect Disord. 2014 May;160:1-9. doi: 10.1016/j.jad.2014.01.009. Epub 2014 Feb 24.

PMID:
24709015
10.

The roles of PDGF in development and during neurogenesis in the normal and diseased nervous system.

Funa K, Sasahara M.

J Neuroimmune Pharmacol. 2014 Mar;9(2):168-81. doi: 10.1007/s11481-013-9479-z. Epub 2013 Jun 15. Review.

11.

Functional analysis of platelet-derived growth factor receptor-β in neural stem/progenitor cells.

Xu G, Shen J, Ishii Y, Fukuchi M, Dang TC, Zheng Y, Hamashima T, Fujimori T, Tsuda M, Funa K, Sasahara M.

Neuroscience. 2013 May 15;238:195-208. doi: 10.1016/j.neuroscience.2013.02.021. Epub 2013 Feb 20.

PMID:
23454370
12.

TLX controls angiogenesis through interaction with the von Hippel-Lindau protein.

Zeng ZJ, Johansson E, Hayashi A, Chavali PL, Akrap N, Yoshida T, Kohno K, Izumi H, Funa K.

Biol Open. 2012 Jun 15;1(6):527-35. doi: 10.1242/bio.2012893. Epub 2012 Apr 18.

13.

Cis-regulation of microRNA expression by scaffold/matrix-attachment regions.

Chavali PL, Funa K, Chavali S.

Nucleic Acids Res. 2011 Sep 1;39(16):6908-18. doi: 10.1093/nar/gkr303. Epub 2011 May 17.

14.

Network modeling of the transcriptional effects of copy number aberrations in glioblastoma.

Jörnsten R, Abenius T, Kling T, Schmidt L, Johansson E, Nordling TE, Nordlander B, Sander C, Gennemark P, Funa K, Nilsson B, Lindahl L, Nelander S.

Mol Syst Biol. 2011 Apr 26;7:486. doi: 10.1038/msb.2011.17.

15.

Nuclear orphan receptor TLX induces Oct-3/4 for the survival and maintenance of adult hippocampal progenitors upon hypoxia.

Chavali PL, Saini RK, Matsumoto Y, Ågren H, Funa K.

J Biol Chem. 2011 Mar 18;286(11):9393-404. doi: 10.1074/jbc.M110.167445. Epub 2010 Dec 6.

16.

Exogenous introduction of tissue inhibitor of metalloproteinase 2 reduces accelerated growth of TGF-β-disrupted diffuse-type gastric carcinoma.

Johansson E, Komuro A, Iwata C, Hagiwara A, Fuse Y, Watanabe A, Morishita Y, Aburatani H, Funa K, Kano MR, Miyazono K.

Cancer Sci. 2010 Nov;101(11):2398-403. doi: 10.1111/j.1349-7006.2010.01688.x.

17.

TLX activates MASH1 for induction of neuronal lineage commitment of adult hippocampal neuroprogenitors.

Elmi M, Matsumoto Y, Zeng ZJ, Lakshminarasimhan P, Yang W, Uemura A, Nishikawa S, Moshiri A, Tajima N, Agren H, Funa K.

Mol Cell Neurosci. 2010 Oct;45(2):121-31. doi: 10.1016/j.mcn.2010.06.003. Epub 2010 Jun 18.

PMID:
20599619
18.

Platelet-derived growth factor-mediated induction of the synaptic plasticity gene Arc/Arg3.1.

Peng F, Yao H, Bai X, Zhu X, Reiner BC, Beazely M, Funa K, Xiong H, Buch S.

J Biol Chem. 2010 Jul 9;285(28):21615-24. doi: 10.1074/jbc.M110.107003. Epub 2010 May 7.

19.

Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration.

Yao H, Yang Y, Kim KJ, Bethel-Brown C, Gong N, Funa K, Gendelman HE, Su TP, Wang JQ, Buch S.

Blood. 2010 Jun 10;115(23):4951-62. doi: 10.1182/blood-2010-01-266221. Epub 2010 Mar 30.

20.

Dysregulation of platelet-derived growth factor beta-receptor expression by DeltaNp73 in neuroblastoma.

Wetterskog D, Moshiri A, Ozaki T, Uramoto H, Nakagawara A, Funa K.

Mol Cancer Res. 2009 Dec;7(12):2031-9. doi: 10.1158/1541-7786.MCR-08-0501. Epub 2009 Dec 1.

21.

Hypercholesterolemia leads to elevated TGF-beta1 activity and T helper 3-dependent autoimmune responses in atherosclerotic mice.

Zhou X, Johnston TP, Johansson D, Parini P, Funa K, Svensson J, Hansson GK.

Atherosclerosis. 2009 Jun;204(2):381-7. doi: 10.1016/j.atherosclerosis.2008.10.017. Epub 2008 Oct 25.

PMID:
19054515
22.

Kinetics of repression by modified p53 on the PDGF beta-receptor promoter.

Yang W, Wetterskog D, Matsumoto Y, Funa K.

Int J Cancer. 2008 Nov 1;123(9):2020-30. doi: 10.1002/ijc.23735.

23.

Opposing effects of retinoid signaling on astrogliogenesis in embryonic day 13 and 17 cortical progenitor cells.

Faigle R, Liu L, Cundiff P, Funa K, Xia Z.

J Neurochem. 2008 Aug;106(4):1681-98. doi: 10.1111/j.1471-4159.2008.05525.x. Epub 2008 Jun 28.

24.

Characterization of neuroprogenitor cells expressing the PDGF beta-receptor within the subventricular zone of postnatal mice.

Ishii Y, Matsumoto Y, Watanabe R, Elmi M, Fujimori T, Nissen J, Cao Y, Nabeshima Y, Sasahara M, Funa K.

Mol Cell Neurosci. 2008 Mar;37(3):507-18. doi: 10.1016/j.mcn.2007.11.006. Epub 2007 Dec 3.

PMID:
18243733
25.

Angiogenic factors FGF2 and PDGF-BB synergistically promote murine tumor neovascularization and metastasis.

Nissen LJ, Cao R, Hedlund EM, Wang Z, Zhao X, Wetterskog D, Funa K, Bråkenhielm E, Cao Y.

J Clin Invest. 2007 Oct;117(10):2766-77.

26.

Mechanism of MASH1 induction by ASK1 and ATRA in adult neural progenitors.

Elmi M, Faigle R, Yang W, Matsumoto Y, Rosenqvist E, Funa K.

Mol Cell Neurosci. 2007 Oct;36(2):248-59. Epub 2007 Jul 21.

PMID:
17728141
27.

A novel MASH1 enhancer with N-myc and CREB-binding sites is active in neuroblastoma.

Watt F, Watanabe R, Yang W, Agren N, Arvidsson Y, Funa K.

Cancer Gene Ther. 2007 Mar;14(3):287-96. Epub 2006 Nov 24.

PMID:
17124508
28.

Remission of collagen-induced arthritis is associated with high levels of transforming growth factor-beta expression in the joint.

Marinova-Mutafchieva L, Gabay C, Funa K, Williams RO.

Clin Exp Immunol. 2006 Nov;146(2):287-93.

29.

Delta Np73 expression in thyroid neoplasms originating from follicular cells.

Ito Y, Uramoto H, Funa K, Yoshida H, Jikuzono T, Asahi S, Higashiyama T, Tomoda C, Takamura Y, Miya A, Kobayashi K, Matsuzuka F, Kuma K, Miyauchi A.

Pathology. 2006 Jun;38(3):205-9.

PMID:
16753740
30.

Activity of a novel PDGF beta-receptor enhancer during the cell cycle and upon differentiation of neuroblastoma.

Kaneko M, Yang W, Matsumoto Y, Watt F, Funa K.

Exp Cell Res. 2006 Jul 1;312(11):2028-39. Epub 2006 Apr 19.

PMID:
16624290
31.

Transplantation of human embryonic stem cell-derived cells to a rat model of Parkinson's disease: effect of in vitro differentiation on graft survival and teratoma formation.

Brederlau A, Correia AS, Anisimov SV, Elmi M, Paul G, Roybon L, Morizane A, Bergquist F, Riebe I, Nannmark U, Carta M, Hanse E, Takahashi J, Sasai Y, Funa K, Brundin P, Eriksson PS, Li JY.

Stem Cells. 2006 Jun;24(6):1433-40. Epub 2006 Mar 23.

32.

Ischemia-induced renal expression of hyaluronan and CD44 in diabetic rats.

Melin J, Hellberg O, Funa K, Hällgren R, Larsson E, Fellström BC.

Nephron Exp Nephrol. 2006;103(3):e86-94. Epub 2006 Mar 22.

PMID:
16554665
33.

Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway.

Sharov AA, Fessing M, Atoyan R, Sharova TY, Haskell-Luevano C, Weiner L, Funa K, Brissette JL, Gilchrest BA, Botchkarev VA.

Proc Natl Acad Sci U S A. 2005 Jan 4;102(1):93-8. Epub 2004 Dec 23.

34.

Expression of deltaNp73 predicts poor prognosis in lung cancer.

Uramoto H, Sugio K, Oyama T, Nakata S, Ono K, Morita M, Funa K, Yasumoto K.

Clin Cancer Res. 2004 Oct 15;10(20):6905-11.

35.

p73 competes with co-activators and recruits histone deacetylase to NF-Y in the repression of PDGF beta-receptor.

Uramoto H, Wetterskog D, Hackzell A, Matsumoto Y, Funa K.

J Cell Sci. 2004 Oct 15;117(Pt 22):5323-31. Epub 2004 Sep 28.

36.

Neuroblastoma-specific cytotoxicity mediated by the Mash1-promoter and E. coli purine nucleoside phosphorylase.

Arvidsson Y, Sumantran V, Watt F, Uramoto H, Funa K.

Pediatr Blood Cancer. 2005 Jan;44(1):77-84.

PMID:
15390277
37.

Association of platelet-derived growth factor-B chain with simian human immunodeficiency virus encephalitis.

Potula R, Dhillion N, Sui Y, Zien CA, Funa K, Pinson D, Mayo MS, Singh DK, Narayan O, Buch S.

Am J Pathol. 2004 Sep;165(3):815-24.

38.

pRb, Myc and p53 are critically involved in SV40 large T antigen repression of PDGF beta-receptor transcription.

Uramoto H, Hackzell A, Wetterskog D, Ballági A, Izumi H, Funa K.

J Cell Sci. 2004 Aug 1;117(Pt 17):3855-65. Epub 2004 Jul 20.

39.

The bone morphogenetic protein type Ib receptor is a major mediator of glial differentiation and cell survival in adult hippocampal progenitor cell culture.

Brederlau A, Faigle R, Elmi M, Zarebski A, Sjöberg S, Fujii M, Miyazono K, Funa K.

Mol Biol Cell. 2004 Aug;15(8):3863-75. Epub 2004 Jun 11.

40.

The PDGF B-chain is involved in the ontogenic susceptibility of the developing rat brain to NMDA toxicity.

Egawa-Tsuzuki T, Ohno M, Tanaka N, Takeuchi Y, Uramoto H, Faigle R, Funa K, Ishii Y, Sasahara M.

Exp Neurol. 2004 Mar;186(1):89-98.

PMID:
14980813
41.
42.
43.

BMP-6 and retinoic acid synergistically differentiate the IMR-32 human neuroblastoma cells.

Sumantran VN, Brederlau A, Funa K.

Anticancer Res. 2003 Mar-Apr;23(2B):1297-303.

PMID:
12820386
44.

Noggin overexpression inhibits eyelid opening by altering epidermal apoptosis and differentiation.

Sharov AA, Weiner L, Sharova TY, Siebenhaar F, Atoyan R, Reginato AM, McNamara CA, Funa K, Gilchrest BA, Brissette JL, Botchkarev VA.

EMBO J. 2003 Jun 16;22(12):2992-3003.

45.

Bone morphogenetic proteins but not growth differentiation factors induce dopaminergic differentiation in mesencephalic precursors.

Brederlau A, Faigle R, Kaplan P, Odin P, Funa K.

Mol Cell Neurosci. 2002 Nov;21(3):367-78.

PMID:
12498780
46.

Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells.

Andrae J, Molander C, Smits A, Funa K, Nistér M.

Biochem Biophys Res Commun. 2002 Aug 23;296(3):604-11.

PMID:
12176024
47.

p73 independent of c-Myc represses transcription of platelet-derived growth factor beta-receptor through interaction with NF-Y.

Hackzell A, Uramoto H, Izumi H, Kohno K, Funa K.

J Biol Chem. 2002 Oct 18;277(42):39769-76. Epub 2002 Aug 6.

48.

Sp1 is a key regulator of the PDGF beta-receptor transcription.

Molander C, Hackzell A, Ohta M, Izumi H, Funa K.

Mol Biol Rep. 2001;28(4):223-33.

PMID:
12153142
49.

p73 Interacts with c-Myc to regulate Y-box-binding protein-1 expression.

Uramoto H, Izumi H, Ise T, Tada M, Uchiumi T, Kuwano M, Yasumoto K, Funa K, Kohno K.

J Biol Chem. 2002 Aug 30;277(35):31694-702. Epub 2002 Jun 21.

50.

Modulation of BMP signaling by noggin is required for induction of the secondary (nontylotrich) hair follicles.

Botchkarev VA, Botchkareva NV, Sharov AA, Funa K, Huber O, Gilchrest BA.

J Invest Dermatol. 2002 Jan;118(1):3-10.

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