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Items: 16


Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine.

Garcia TB, Fosmire SP, Porter CC.

Leuk Res. 2018 Jan;64:30-33. doi: 10.1016/j.leukres.2017.11.004. Epub 2017 Nov 11.


A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.

Garcia TB, Snedeker JC, Baturin D, Gardner L, Fosmire SP, Zhou C, Jordan CT, Venkataraman S, Vibhakar R, Porter CC.

Mol Cancer Ther. 2017 Oct;16(10):2058-2068. doi: 10.1158/1535-7163.MCT-16-0660. Epub 2017 Jun 27.


STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious.

Maycotte P, Gearheart CM, Barnard R, Aryal S, Mulcahy Levy JM, Fosmire SP, Hansen RJ, Morgan MJ, Porter CC, Gustafson DL, Thorburn A.

Cancer Res. 2014 May 1;74(9):2579-90. doi: 10.1158/0008-5472.CAN-13-3470. Epub 2014 Mar 3.


Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality.

Van Linden AA, Baturin D, Ford JB, Fosmire SP, Gardner L, Korch C, Reigan P, Porter CC.

Mol Cancer Ther. 2013 Dec;12(12):2675-84. doi: 10.1158/1535-7163.MCT-13-0424. Epub 2013 Oct 11.


Gene expression profiling identifies inflammation and angiogenesis as distinguishing features of canine hemangiosarcoma.

Tamburini BA, Phang TL, Fosmire SP, Scott MC, Trapp SC, Duckett MM, Robinson SR, Slansky JE, Sharkey LC, Cutter GR, Wojcieszyn JW, Bellgrau D, Gemmill RM, Hunter LE, Modiano JF.

BMC Cancer. 2010 Nov 9;10:619. doi: 10.1186/1471-2407-10-619.


Nicotine-mediated signals modulate cell death and survival of T lymphocytes.

Oloris SC, Frazer-Abel AA, Jubala CM, Fosmire SP, Helm KM, Robinson SR, Korpela DM, Duckett MM, Baksh S, Modiano JF.

Toxicol Appl Pharmacol. 2010 Feb 1;242(3):299-309. doi: 10.1016/j.taap.2009.10.020. Epub 2009 Nov 4.


Influence of genetic background on tumor karyotypes: evidence for breed-associated cytogenetic aberrations in canine appendicular osteosarcoma.

Thomas R, Wang HJ, Tsai PC, Langford CF, Fosmire SP, Jubala CM, Getzy DM, Cutter GR, Modiano JF, Breen M.

Chromosome Res. 2009;17(3):365-377. doi: 10.1007/s10577-009-9028-z. Epub 2009 Apr 1.


Inactivation of the p16 cyclin-dependent kinase inhibitor in high-grade canine non-Hodgkin's T-cell lymphoma.

Fosmire SP, Thomas R, Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Smith TL, Gardner LA, Ritt MG, Bell JS, Freeman KP, Greenfield BE, Lana SE, Kisseberth WC, Helfand SC, Cutter GR, Breen M, Modiano JF.

Vet Pathol. 2007 Jul;44(4):467-78.


Construction of a 2-Mb resolution BAC microarray for CGH analysis of canine tumors.

Thomas R, Scott A, Langford CF, Fosmire SP, Jubala CM, Lorentzen TD, Hitte C, Karlsson EK, Kirkness E, Ostrander EA, Galibert F, Lindblad-Toh K, Modiano JF, Breen M.

Genome Res. 2005 Dec;15(12):1831-7.


Mutations of phosphatase and tensin homolog deleted from chromosome 10 in canine hemangiosarcoma.

Dickerson EB, Thomas R, Fosmire SP, Lamerato-Kozicki AR, Bianco SR, Wojcieszyn JW, Breen M, Helfand SC, Modiano JF.

Vet Pathol. 2005 Sep;42(5):618-32.


CD20 expression in normal canine B cells and in canine non-Hodgkin lymphoma.

Jubala CM, Wojcieszyn JW, Valli VE, Getzy DM, Fosmire SP, Coffey D, Bellgrau D, Modiano JF.

Vet Pathol. 2005 Jul;42(4):468-76.


Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells.

Frazer-Abel AA, Baksh S, Fosmire SP, Willis D, Pierce AM, Meylemans H, Linthicum DS, Burakoff SJ, Coons T, Bellgrau D, Modiano JF.

J Pharmacol Exp Ther. 2004 Nov;311(2):758-69. Epub 2004 Jul 1.


Canine malignant hemangiosarcoma as a model of primitive angiogenic endothelium.

Fosmire SP, Dickerson EB, Scott AM, Bianco SR, Pettengill MJ, Meylemans H, Padilla M, Frazer-Abel AA, Akhtar N, Getzy DM, Wojcieszyn J, Breen M, Helfand SC, Modiano JF.

Lab Invest. 2004 May;84(5):562-72.


Enhancing antimelanoma immune responses through apoptosis.

Bianco SR, Sun J, Fosmire SP, Hance K, Padilla ML, Ritt MG, Getzy DM, Duke RC, Withrow SJ, Lana S, Matthiesen DT, Dow SW, Bellgrau D, Cutter GR, Helfand SC, Modiano JF.

Cancer Gene Ther. 2003 Sep;10(9):726-36.


Further identification of protein kinase C isozymes in mouse epidermis.

Wang XJ, Warren BS, Beltrán LM, Fosmire SP, DiGiovanni J.

J Cancer Res Clin Oncol. 1993;119(5):279-87.


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