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Items: 1 to 50 of 444

1.

Advancing systems immunology through data-driven statistical analysis.

Fong LE, Muñoz-Rojas AR, Miller-Jensen K.

Curr Opin Biotechnol. 2018 Apr 12;52:109-115. doi: 10.1016/j.copbio.2018.03.009. [Epub ahead of print] Review.

PMID:
29656236
2.

Shuffling the deck with CTLA-4 therapy: Deep sequencing of rearranged TCRB genes demonstrates T cell repertoire remodeling in cancer patients.

Cha E, Fong L.

Oncoimmunology. 2018 Mar 13;7(4):e956016. doi: 10.4161/21624011.2014.956016. eCollection 2018.

PMID:
29632706
3.

Health-Related Quality-of-Life Analysis From KEYNOTE-045: A Phase III Study of Pembrolizumab Versus Chemotherapy for Previously Treated Advanced Urothelial Cancer.

Vaughn DJ, Bellmunt J, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Li H, Perini RF, Bajorin DF, de Wit R.

J Clin Oncol. 2018 Mar 28:JCO2017769562. doi: 10.1200/JCO.2017.76.9562. [Epub ahead of print]

PMID:
29590008
4.

The Impact of the Roast Levels of Coffee Extracts on their Potential Anticancer Activities.

Mojica BE, Fong LE, Biju D, Muharram A, Davis IM, Vela KO, Rios D, Osorio-Camacena E, Kaur B, Rojas SM, Forester SC.

J Food Sci. 2018 Apr;83(4):1125-1130. doi: 10.1111/1750-3841.14102. Epub 2018 Mar 25.

PMID:
29577313
5.

Immunotherapy for Prostate Cancer: Where Do We Go From Here?-PART 1: Prostate Cancer Vaccines.

Patel A, Fong L.

Oncology (Williston Park). 2018 Mar 15;32(3):112-20. Review.

6.

Single-cell RNA sequencing reveals gene expression signatures of breast cancer-associated endothelial cells.

Sun Z, Wang CY, Lawson DA, Kwek S, Velozo HG, Owyong M, Lai MD, Fong L, Wilson M, Su H, Werb Z, Cooke DL.

Oncotarget. 2017 Dec 29;9(13):10945-10961. doi: 10.18632/oncotarget.23760. eCollection 2018 Feb 16.

7.

Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein.

Young JE, Fong LK, Frankowski H, Petsko GA, Small SA, Goldstein LSB.

Stem Cell Reports. 2018 Mar 13;10(3):1046-1058. doi: 10.1016/j.stemcr.2018.01.031. Epub 2018 Mar 1.

8.

A Phase II Trial of Selinexor, an Oral Selective Inhibitor of Nuclear Export Compound, in Abiraterone- and/or Enzalutamide-Refractory Metastatic Castration-Resistant Prostate Cancer.

Wei XX, Siegel AP, Aggarwal R, Lin AM, Friedlander TW, Fong L, Kim W, Louttit M, Chang E, Zhang L, Ryan CJ.

Oncologist. 2018 Feb 27. pii: theoncologist.2017-0624. doi: 10.1634/theoncologist.2017-0624. [Epub ahead of print]

PMID:
29487219
9.

Impaired thermogenesis and sharp increases in plasma triglyceride levels in GPIHBP1-deficient mice during cold exposure.

Larsson M, Allan CM, Heizer PJ, Tu Y, Sandoval NP, Jung RS, Walzem RL, Beigneux AP, Young SG, Fong LG.

J Lipid Res. 2018 Apr;59(4):706-713. doi: 10.1194/jlr.M083832. Epub 2018 Feb 15.

PMID:
29449313
10.

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan S, Turley SJ, Nickles D, Castiglioni A, Yuen K, Wang Y, Kadel Iii EE, Koeppen H, Astarita JL, Cubas R, Jhunjhunwala S, Banchereau R, Yang Y, Guan Y, Chalouni C, Ziai J, Şenbabaoğlu Y, Santoro S, Sheinson D, Hung J, Giltnane JM, Pierce AA, Mesh K, Lianoglou S, Riegler J, Carano RAD, Eriksson P, Höglund M, Somarriba L, Halligan DL, van der Heijden MS, Loriot Y, Rosenberg JE, Fong L, Mellman I, Chen DS, Green M, Derleth C, Fine GD, Hegde PS, Bourgon R, Powles T.

Nature. 2018 Feb 22;554(7693):544-548. doi: 10.1038/nature25501. Epub 2018 Feb 14.

PMID:
29443960
11.

Historical atmospheric pollution trends in Southeast Asia inferred from lake sediment records.

Engels S, Fong LSRZ, Chen Q, Leng MJ, McGowan S, Idris M, Rose NL, Ruslan MS, Taylor D, Yang H.

Environ Pollut. 2018 Apr;235:907-917. doi: 10.1016/j.envpol.2018.01.007. Epub 2018 Feb 21.

PMID:
29353806
12.

Clinical Variables Associated With Overall Survival in Metastatic Castration-Resistant Prostate Cancer Patients Treated With Sipuleucel-T Immunotherapy.

Wei XX, Perry J, Chang E, Zhang L, Hiatt RA, Ryan CJ, Small EJ, Fong L.

Clin Genitourin Cancer. 2017 Dec 27. pii: S1558-7673(17)30390-7. doi: 10.1016/j.clgc.2017.12.004. [Epub ahead of print]

PMID:
29352713
13.

IL-10 Signaling Remodels Adipose Chromatin Architecture to Limit Thermogenesis and Energy Expenditure.

Rajbhandari P, Thomas BJ, Feng AC, Hong C, Wang J, Vergnes L, Sallam T, Wang B, Sandhu J, Seldin MM, Lusis AJ, Fong LG, Katz M, Lee R, Young SG, Reue K, Smale ST, Tontonoz P.

Cell. 2018 Jan 11;172(1-2):218-233.e17. doi: 10.1016/j.cell.2017.11.019. Epub 2017 Dec 14.

PMID:
29249357
14.

Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells.

Fong LE, Sulistijo ES, Miller-Jensen K.

Sci Rep. 2017 Nov 23;7(1):16179. doi: 10.1038/s41598-017-15532-0.

15.

Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia.

Fong LY, Jing R, Smalley KJ, Taccioli C, Fahrmann J, Barupal DK, Alder H, Farber JL, Fiehn O, Croce CM.

Oncotarget. 2017 Jun 9;8(47):81910-81925. doi: 10.18632/oncotarget.18434. eCollection 2017 Oct 10.

16.

Imaging PD-L1 Expression with ImmunoPET.

Truillet C, Oh HLJ, Yeo SP, Lee CY, Huynh LT, Wei J, Parker MFL, Blakely C, Sevillano N, Wang YH, Shen YS, Olivas V, Jami KM, Moroz A, Jego B, Jaumain E, Fong L, Craik CS, Chang AJ, Bivona TG, Wang CI, Evans MJ.

Bioconjug Chem. 2018 Jan 17;29(1):96-103. doi: 10.1021/acs.bioconjchem.7b00631. Epub 2017 Nov 15.

17.

Lipoprotein lipase reaches the capillary lumen in chickens despite an apparent absence of GPIHBP1.

He C, Hu X, Jung RS, Larsson M, Tu Y, Duarte-Vogel S, Kim P, Sandoval NP, Price TR, Allan CM, Raney B, Jiang H, Bensadoun A, Walzem RL, Kuo RI, Beigneux AP, Fong LG, Young SG.

JCI Insight. 2017 Oct 19;2(20). pii: 96783. doi: 10.1172/jci.insight.96783. [Epub ahead of print]

18.

Myristoylated alanine-rich C kinase substrate (MARCKS): a multirole signaling protein in cancers.

Fong LWR, Yang DC, Chen CH.

Cancer Metastasis Rev. 2017 Dec;36(4):737-747. doi: 10.1007/s10555-017-9709-6. Review.

PMID:
29039083
19.

Palmoplantar keratoderma in Slurp1/Slurp2 double-knockout mice.

Allan CM, Heizer PJ, Jung CJ, Tu Y, Tran D, Young LC, Fong LG, de Jong PJ, Beigneux AP, Young SG.

J Dermatol Sci. 2018 Jan;89(1):85-87. doi: 10.1016/j.jdermsci.2017.08.014. Epub 2017 Sep 28. No abstract available.

PMID:
29017797
20.

Combination central tolerance and peripheral checkpoint blockade unleashes antimelanoma immunity.

Bakhru P, Zhu ML, Wang HH, Hong LK, Khan I, Mouchess M, Gulati AS, Starmer J, Hou Y, Sailer D, Lee S, Zhao F, Kirkwood JM, Moschos S, Fong L, Anderson MS, Su MA.

JCI Insight. 2017 Sep 21;2(18). pii: 93265. doi: 10.1172/jci.insight.93265. [Epub ahead of print]

21.

Predictors of responses to immune checkpoint blockade in advanced melanoma.

Jacquelot N, Roberti MP, Enot DP, Rusakiewicz S, Ternès N, Jegou S, Woods DM, Sodré AL, Hansen M, Meirow Y, Sade-Feldman M, Burra A, Kwek SS, Flament C, Messaoudene M, Duong CPM, Chen L, Kwon BS, Anderson AC, Kuchroo VK, Weide B, Aubin F, Borg C, Dalle S, Beatrix O, Ayyoub M, Balme B, Tomasic G, Di Giacomo AM, Maio M, Schadendorf D, Melero I, Dréno B, Khammari A, Dummer R, Levesque M, Koguchi Y, Fong L, Lotem M, Baniyash M, Schmidt H, Svane IM, Kroemer G, Marabelle A, Michiels S, Cavalcanti A, Smyth MJ, Weber JS, Eggermont AM, Zitvogel L.

Nat Commun. 2017 Sep 19;8(1):592. doi: 10.1038/s41467-017-00608-2.

22.

Anti-arthritic and gastroprotective activities of Ardisia crispa root partially mediated via its antioxidant effect.

Hamid RA, Fong LM, Ting YL.

J Complement Integr Med. 2017 Sep 14;15(1). pii: /j/jcim.2018.15.issue-1/jcim-2017-0012/jcim-2017-0012.xml. doi: 10.1515/jcim-2017-0012.

PMID:
28915115
23.

Surgical Management of Caseous Calcification of the Mitral Annulus.

Fong LS, McLaughlin AJ, Okiwelu NL, Nordstrand IAJ, Newman M, Passage J, Joshi PV.

Ann Thorac Surg. 2017 Sep;104(3):e291-e293. doi: 10.1016/j.athoracsur.2017.04.039.

PMID:
28838533
24.

Early Probiotic Supplementation for Eczema and Asthma Prevention: A Randomized Controlled Trial.

Cabana MD, McKean M, Caughey AB, Fong L, Lynch S, Wong A, Leong R, Boushey HA, Hilton JF.

Pediatrics. 2017 Sep;140(3). pii: e20163000. doi: 10.1542/peds.2016-3000. Epub 2017 Aug 7.

PMID:
28784701
25.

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL.

Larsson M, Allan CM, Jung RS, Heizer PJ, Beigneux AP, Young SG, Fong LG.

J Lipid Res. 2017 Sep;58(9):1893-1902. doi: 10.1194/jlr.M078220. Epub 2017 Jul 10.

PMID:
28694296
26.

GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia.

Hu X, Dallinga-Thie GM, Hovingh GK, Chang SY, Sandoval NP, Dang TLP, Fukamachi I, Miyashita K, Nakajima K, Murakami M, Fong LG, Ploug M, Young SG, Beigneux AP.

J Clin Lipidol. 2017 Jul - Aug;11(4):964-971. doi: 10.1016/j.jacl.2017.05.017. Epub 2017 Jun 13.

PMID:
28666713
27.

High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer.

Friedlander TW, Graff JN, Zejnullahu K, Anantharaman A, Zhang L, Paz R, Premasekharan G, Russell C, Huang Y, Kim W, Aggarwal RR, Lin AM, Fong L, Alumkal JJ, Beer TM, Sharifi N, Alyamani M, Dittamore R, Small EJ, Paris PL, Ryan CJ.

Clin Genitourin Cancer. 2017 Dec;15(6):733-741.e1. doi: 10.1016/j.clgc.2017.05.026. Epub 2017 Jun 3.

PMID:
28655452
28.

Bone Scintigraphy and Tenofovir-Induced Osteomalacia in Chronic Hepatitis B.

Hoe AKC, Fong LY.

Nucl Med Mol Imaging. 2017 Jun;51(2):195-196. doi: 10.1007/s13139-016-0395-z. Epub 2016 Jan 26.

PMID:
28559948
29.

Television During Meals in the First 4 Years of Life.

Thimmig LM, Cabana MD, Bentz MG, Potocka K, Beck A, Fong L, Chao C, Caughey AB, Wong A, McKean M.

Clin Pediatr (Phila). 2017 Jun;56(7):659-666. doi: 10.1177/0009922816678585. Epub 2016 Nov 16.

PMID:
28503997
30.

Mutating a conserved cysteine in GPIHBP1 reduces amounts of GPIHBP1 in capillaries and abolishes LPL binding.

Allan CM, Jung CJ, Larsson M, Heizer PJ, Tu Y, Sandoval NP, Dang TLP, Jung RS, Beigneux AP, de Jong PJ, Fong LG, Young SG.

J Lipid Res. 2017 Jul;58(7):1453-1461. doi: 10.1194/jlr.M076943. Epub 2017 May 5.

PMID:
28476858
31.

A hypomorphic Egfr allele does not ameliorate the palmoplantar keratoderma caused by SLURP1 deficiency.

Allan CM, Tran D, Tu Y, Heizer PJ, Young LC, Fong LG, Beigneux AP, Young SG.

Exp Dermatol. 2017 Nov;26(11):1134-1136. doi: 10.1111/exd.13363. Epub 2017 Jul 27.

PMID:
28418591
32.

Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia.

Beigneux AP, Miyashita K, Ploug M, Blom DJ, Ai M, Linton MF, Khovidhunkit W, Dufour R, Garg A, McMahon MA, Pullinger CR, Sandoval NP, Hu X, Allan CM, Larsson M, Machida T, Murakami M, Reue K, Tontonoz P, Goldberg IJ, Moulin P, Charrière S, Fong LG, Nakajima K, Young SG.

N Engl J Med. 2017 Apr 27;376(17):1647-1658. doi: 10.1056/NEJMoa1611930. Epub 2017 Apr 5.

33.

Fundamental Motor Skill Proficiency of 6- to 9-Year-Old Singaporean Children.

Mukherjee S, Ting Jamie LC, Fong LH.

Percept Mot Skills. 2017 Jun;124(3):584-600. doi: 10.1177/0031512517703005. Epub 2017 Apr 4.

PMID:
28376671
34.

3D: diversity, dynamics, differential testing - a proposed pipeline for analysis of next-generation sequencing T cell repertoire data.

Zhang L, Cham J, Paciorek A, Trager J, Sheikh N, Fong L.

BMC Bioinformatics. 2017 Feb 27;18(1):129. doi: 10.1186/s12859-017-1544-9.

35.

Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma.

Bellmunt J, de Wit R, Vaughn DJ, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Poehlein CH, Perini RF, Bajorin DF; KEYNOTE-045 Investigators.

N Engl J Med. 2017 Mar 16;376(11):1015-1026. doi: 10.1056/NEJMoa1613683. Epub 2017 Feb 17.

36.

High-resolution imaging and quantification of plasma membrane cholesterol by NanoSIMS.

He C, Hu X, Jung RS, Weston TA, Sandoval NP, Tontonoz P, Kilburn MR, Fong LG, Young SG, Jiang H.

Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):2000-2005. doi: 10.1073/pnas.1621432114. Epub 2017 Feb 6.

37.

Upregulation of MARCKS in kidney cancer and its potential as a therapeutic target.

Chen CH, Fong LWR, Yu E, Wu R, Trott JF, Weiss RH.

Oncogene. 2017 Jun 22;36(25):3588-3598. doi: 10.1038/onc.2016.510. Epub 2017 Feb 6.

PMID:
28166200
38.

Systemic Immunity Is Required for Effective Cancer Immunotherapy.

Spitzer MH, Carmi Y, Reticker-Flynn NE, Kwek SS, Madhireddy D, Martins MM, Gherardini PF, Prestwood TR, Chabon J, Bendall SC, Fong L, Nolan GP, Engleman EG.

Cell. 2017 Jan 26;168(3):487-502.e15. doi: 10.1016/j.cell.2016.12.022. Epub 2017 Jan 19.

39.

Can Prostate Cancer Really Respond to Immunotherapy?

Kim W, Fong L.

J Clin Oncol. 2017 Jan;35(1):4-5. Epub 2016 Nov 14. No abstract available.

PMID:
28034060
40.

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of prostate carcinoma.

McNeel DG, Bander NH, Beer TM, Drake CG, Fong L, Harrelson S, Kantoff PW, Madan RA, Oh WK, Peace DJ, Petrylak DP, Porterfield H, Sartor O, Shore ND, Slovin SF, Stein MN, Vieweg J, Gulley JL.

J Immunother Cancer. 2016 Dec 20;4:92. doi: 10.1186/s40425-016-0198-x. eCollection 2016.

41.

Immune Toxicities Elicted by CTLA-4 Blockade in Cancer Patients Are Associated with Early Diversification of the T-cell Repertoire.

Oh DY, Cham J, Zhang L, Fong G, Kwek SS, Klinger M, Faham M, Fong L.

Cancer Res. 2017 Mar 15;77(6):1322-1330. doi: 10.1158/0008-5472.CAN-16-2324. Epub 2016 Dec 28.

42.

Correction: TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.

Sulak M, Fong L, Mika K, Chigurupati S, Yon L, Mongan NP, Emes RD, Lynch VJ.

Elife. 2016 Dec 20;5. pii: e24307. doi: 10.7554/eLife.24307. No abstract available.

43.

Monoclonal antibodies that bind to the Ly6 domain of GPIHBP1 abolish the binding of LPL.

Hu X, Sleeman MW, Miyashita K, Linton MF, Allan CM, He C, Larsson M, Tu Y, Sandoval NP, Jung RS, Mapar A, Machida T, Murakami M, Nakajima K, Ploug M, Fong LG, Young SG, Beigneux AP.

J Lipid Res. 2017 Jan;58(1):208-215. doi: 10.1194/jlr.M072462. Epub 2016 Nov 15.

44.

LMNA missense mutations causing familial partial lipodystrophy do not lead to an accumulation of prelamin A.

Tu Y, Sánchez-Iglesias S, Araújo-Vilar D, Fong LG, Young SG.

Nucleus. 2016 Sep 2;7(5):512-521.

45.

Mobility of "HSPG-bound" LPL explains how LPL is able to reach GPIHBP1 on capillaries.

Allan CM, Larsson M, Jung RS, Ploug M, Bensadoun A, Beigneux AP, Fong LG, Young SG.

J Lipid Res. 2017 Jan;58(1):216-225. doi: 10.1194/jlr.M072520. Epub 2016 Nov 3.

46.

Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L.

Cancer Immunol Res. 2016 Nov;4(11):948-958. Epub 2016 Sep 29.

47.

Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma.

Choueiri TK, Fishman MN, Escudier B, McDermott DF, Drake CG, Kluger H, Stadler WM, Perez-Gracia JL, McNeel DG, Curti B, Harrison MR, Plimack ER, Appleman L, Fong L, Albiges L, Cohen L, Young TC, Chasalow SD, Ross-Macdonald P, Srivastava S, Jure-Kunkel M, Kurland JF, Simon JS, Sznol M.

Clin Cancer Res. 2016 Nov 15;22(22):5461-5471. doi: 10.1158/1078-0432.CCR-15-2839. Epub 2016 May 11.

48.

NanoSIMS imaging: an approach for visualizing and quantifying lipids in cells and tissues.

He C, Fong LG, Young SG, Jiang H.

J Investig Med. 2017 Mar;65(3):669-672. doi: 10.1136/jim-2016-000239. Epub 2016 Oct 28. Review.

49.

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.

Sulak M, Fong L, Mika K, Chigurupati S, Yon L, Mongan NP, Emes RD, Lynch VJ.

Elife. 2016 Sep 19;5. pii: e11994. doi: 10.7554/eLife.11994. Erratum in: Elife. 2016 Dec 20;5:.

50.

Nitric oxide participates in IFN-gamma-induced HUVECs hyperpermeability.

Ng CT, Fong LY, Low YY, Ban J, Hakim MN, Ahmad Z.

Physiol Res. 2016 Dec 13;65(6):1053-1058. Epub 2016 Aug 19.

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