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Items: 1 to 50 of 305

1.

Increased expression of CD44 is associated with more aggressive behavior in clear cell renal cell carcinoma.

Zanjani LS, Madjd Z, Abolhasani M, Rasti A, Fodstad O, Andersson Y, Asgari M.

Biomark Med. 2018 Jan;12(1):45-61. doi: 10.2217/bmm-2017-0142. Epub 2017 Dec 15.

PMID:
29243496
2.

The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy.

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø.

Pathol Oncol Res. 2017 Nov 2. doi: 10.1007/s12253-017-0355-7. [Epub ahead of print]

PMID:
29098521
3.

MOC31PE immunotoxin - targeting peritoneal metastasis from epithelial ovarian cancer.

Andersson Y, Haavardtun SI, Davidson B, Dørum A, Fleten KG, Fodstad Ø, Flatmark K.

Oncotarget. 2017 Jun 27;8(37):61800-61809. doi: 10.18632/oncotarget.18694. eCollection 2017 Sep 22.

4.

Immunoregulatory protein B7-H3 promotes growth and decreases sensitivity to therapy in metastatic melanoma cells.

Flem-Karlsen K, Tekle C, Andersson Y, Flatmark K, Fodstad Ø, Nunes-Xavier CE.

Pigment Cell Melanoma Res. 2017 Sep;30(5):467-476. doi: 10.1111/pcmr.12599. Epub 2017 Jul 4.

PMID:
28513992
5.

Interplay between Immune Checkpoint Proteins and Cellular Metabolism.

Lim S, Phillips JB, Madeira da Silva L, Zhou M, Fodstad O, Owen LB, Tan M.

Cancer Res. 2017 Mar 15;77(6):1245-1249. doi: 10.1158/0008-5472.CAN-16-1647. Epub 2017 Feb 28. Review.

6.

Novel Treatment with Intraperitoneal MOC31PE Immunotoxin in Colorectal Peritoneal Metastasis: Results From the ImmunoPeCa Phase 1 Trial.

Frøysnes IS, Andersson Y, Larsen SG, Davidson B, Øien JT, Olsen KH, Giercksky KE, Julsrud L, Fodstad Ø, Dueland S, Flatmark K.

Ann Surg Oncol. 2017 Jul;24(7):1916-1922. doi: 10.1245/s10434-017-5814-6. Epub 2017 Feb 21.

PMID:
28224367
7.

A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties.

Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø.

Exp Cell Res. 2017 Mar 15;352(2):218-224. doi: 10.1016/j.yexcr.2017.02.005. Epub 2017 Feb 9.

PMID:
28189639
8.

Detection of disseminated tumor cells in lymph nodes from patients with early stage non-small cell lung cancer.

Rud AK, Boye K, Fodstad Ø, Juell S, Jørgensen LH, Solberg S, Helland Å, Brustugun OT, Mælandsmo GM.

Diagn Pathol. 2016 Jun 17;11(1):50. doi: 10.1186/s13000-016-0504-4.

9.

Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α.

Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M.

Cancer Res. 2016 Apr 15;76(8):2231-42. doi: 10.1158/0008-5472.CAN-15-1538. Epub 2016 Apr 5.

10.

Decreased expression of B7-H3 reduces the glycolytic capacity and sensitizes breast cancer cells to AKT/mTOR inhibitors.

Nunes-Xavier CE, Karlsen KF, Tekle C, Pedersen C, Øyjord T, Hongisto V, Nesland JM, Tan M, Sahlberg KK, Fodstad Ø.

Oncotarget. 2016 Feb 9;7(6):6891-901. doi: 10.18632/oncotarget.6902.

11.

Phase I trial of EpCAM-targeting immunotoxin MOC31PE, alone and in combination with cyclosporin.

Andersson Y, Engebraaten O, Juell S, Aamdal S, Brunsvig P, Fodstad Ø, Dueland S.

Br J Cancer. 2015 Dec 1;113(11):1548-55. doi: 10.1038/bjc.2015.380. Epub 2015 Nov 10.

12.

Tumour exosome integrins determine organotropic metastasis.

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Tesic Mark M, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K, Wexler LH, Narendran A, Schwartz GK, Healey JH, Sandstrom P, Labori KJ, Kure EH, Grandgenett PM, Hollingsworth MA, de Sousa M, Kaur S, Jain M, Mallya K, Batra SK, Jarnagin WR, Brady MS, Fodstad O, Muller V, Pantel K, Minn AJ, Bissell MJ, Garcia BA, Kang Y, Rajasekhar VK, Ghajar CM, Matei I, Peinado H, Bromberg J, Lyden D.

Nature. 2015 Nov 19;527(7578):329-35. doi: 10.1038/nature15756. Epub 2015 Oct 28.

13.

Bilateral uveal melanomas with different gene expression detected with 7 years interval.

Eide N, Garred Ø, Beiske K, Fodstad Ø.

Acta Ophthalmol. 2016 Feb;94(1):99-102. doi: 10.1111/aos.12857. Epub 2015 Oct 24.

14.

Interleukin-8 is a key mediator of FKBP51-induced melanoma growth, angiogenesis and metastasis.

Srivastava SK, Bhardwaj A, Arora S, Tyagi N, Singh AP, Carter JE, Scammell JG, Fodstad Ø, Singh S.

Br J Cancer. 2015 May 26;112(11):1772-81. doi: 10.1038/bjc.2015.154. Epub 2015 May 5.

15.

Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox.

Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø.

Acta Ophthalmol. 2015 Feb;93(1):59-66. doi: 10.1111/aos.12462.

16.

B7-H3 expression in colorectal cancer: associations with clinicopathological parameters and patient outcome.

Ingebrigtsen VA, Boye K, Nesland JM, Nesbakken A, Flatmark K, Fodstad Ø.

BMC Cancer. 2014 Aug 20;14:602. doi: 10.1186/1471-2407-14-602.

17.

Identifying microRNAs regulating B7-H3 in breast cancer: the clinical impact of microRNA-29c.

Nygren MK, Tekle C, Ingebrigtsen VA, Mäkelä R, Krohn M, Aure MR, Nunes-Xavier CE, Perälä M, Tramm T, Alsner J, Overgaard J, Nesland JM, Borgen E, Børresen-Dale AL, Fodstad Ø, Sahlberg KK, Leivonen SK.

Br J Cancer. 2014 Apr 15;110(8):2072-80. doi: 10.1038/bjc.2014.113. Epub 2014 Feb 27.

18.

The MOC31PE immunotoxin reduces cell migration and induces gene expression and cell death in ovarian cancer cells.

Wiiger MT, Bideli H, Fodstad O, Flatmark K, Andersson Y.

J Ovarian Res. 2014 Feb 15;7:23. doi: 10.1186/1757-2215-7-23.

19.

Antitumor activity of elacytarabine combined with bevacizumab, cetuximab and trastuzumab in human NSCLC xenografts.

Bruheim S, Sandvold ML, Mælandsmo GM, Fodstad O.

Anticancer Res. 2013 Sep;33(9):3615-21.

PMID:
24023287
20.

Clinical significance of long intergenic noncoding RNA-p21 in colorectal cancer.

Zhai H, Fesler A, Schee K, Fodstad O, Flatmark K, Ju J.

Clin Colorectal Cancer. 2013 Dec;12(4):261-6. doi: 10.1016/j.clcc.2013.06.003. Epub 2013 Sep 5.

PMID:
24012455
21.

Clinical significance of disseminated tumour cells in non-small cell lung cancer.

Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K.

Br J Cancer. 2013 Sep 3;109(5):1264-70. doi: 10.1038/bjc.2013.450. Epub 2013 Aug 13.

22.

Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer.

Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K.

PLoS One. 2013 Jun 18;8(6):e66165. doi: 10.1371/journal.pone.0066165. Print 2013.

23.

In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines.

Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G.

Exp Hematol Oncol. 2013 Jun 6;2(1):16. doi: 10.1186/2162-3619-2-16.

24.

Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies.

Flatmark K, Guldvik IJ, Svensson H, Fleten KG, Flørenes VA, Reed W, Giercksky KE, Fodstad Ø, Andersson Y.

Int J Cancer. 2013 Sep 15;133(6):1497-506. doi: 10.1002/ijc.28158. Epub 2013 Apr 17.

25.

Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7).

Desai S, Liu Z, Yao J, Patel N, Chen J, Wu Y, Ahn EE, Fodstad O, Tan M.

J Biol Chem. 2013 Mar 29;288(13):9165-76. doi: 10.1074/jbc.M112.422071. Epub 2013 Feb 5.

26.

miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance.

Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M.

J Biol Chem. 2013 Feb 8;288(6):4334-45. doi: 10.1074/jbc.M112.419168. Epub 2012 Dec 19.

27.

Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism.

Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M.

Nat Commun. 2012;3:1271. doi: 10.1038/ncomms2236.

28.

Clinical relevance of microRNA miR-21, miR-31, miR-92a, miR-101, miR-106a and miR-145 in colorectal cancer.

Schee K, Boye K, Abrahamsen TW, Fodstad Ø, Flatmark K.

BMC Cancer. 2012 Nov 2;12:505. doi: 10.1186/1471-2407-12-505.

29.

Cytoplasmic translocation of p21 mediates NUPR1-induced chemoresistance: NUPR1 and p21 in chemoresistance.

Vincent AJ, Ren S, Harris LG, Devine DJ, Samant RS, Fodstad O, Shevde LA.

FEBS Lett. 2012 Sep 21;586(19):3429-34. doi: 10.1016/j.febslet.2012.07.063. Epub 2012 Jul 31.

30.

Disseminated tumour cells in bone marrow of patients with uveal melanoma.

Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad Ø.

Acta Ophthalmol. 2013 Jun;91(4):343-8. doi: 10.1111/j.1755-3768.2012.02449.x. Epub 2012 May 25.

31.

B7-H3 expression in colorectal cancer: nuclear localization strongly predicts poor outcome in colon cancer.

Ingebrigtsen VA, Boye K, Tekle C, Nesland JM, Flatmark K, Fodstad O.

Int J Cancer. 2012 Dec 1;131(11):2528-36. doi: 10.1002/ijc.27566. Epub 2012 Apr 24.

32.

Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma.

Hjortland GO, Meza-Zepeda LA, Beiske K, Ree AH, Tveito S, Hoifodt H, Bohler PJ, Hole KH, Myklebost O, Fodstad O, Smeland S, Hovig E.

BMC Cancer. 2011 Oct 20;11:455. doi: 10.1186/1471-2407-11-455.

33.

Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma.

Risberg K, Fodstad Ø, Andersson Y.

PLoS One. 2011;6(9):e24012. doi: 10.1371/journal.pone.0024012. Epub 2011 Sep 7.

34.

Tumor kinase activity in locally advanced rectal cancer: angiogenic signaling and early systemic dissemination.

Saelen MG, Flatmark K, Folkvord S, de Wijn R, Rasmussen H, Fodstad Ø, Ree AH.

Angiogenesis. 2011 Dec;14(4):481-9. doi: 10.1007/s10456-011-9231-3. Epub 2011 Aug 11.

35.
36.

B7-H3 contributes to the metastatic capacity of melanoma cells by modulation of known metastasis-associated genes.

Tekle C, Nygren MK, Chen YW, Dybsjord I, Nesland JM, Maelandsmo GM, Fodstad O.

Int J Cancer. 2012 May 15;130(10):2282-90. doi: 10.1002/ijc.26238. Epub 2011 Aug 8.

37.

B7-H3 and its relevance in cancer; immunological and non-immunological perspectives.

Nygren MK, Tekle C, Ingebrigtsen VA, Fodstad O.

Front Biosci (Elite Ed). 2011 Jun 1;3:989-93. Review.

PMID:
21622107
38.

Immunotoxins: a promising treatment modality for metastatic melanoma?

Risberg K, Fodstad O, Andersson Y.

Ochsner J. 2010 Fall;10(3):193-9.

39.

Triphenylmethyl derivatives enhances the anticancer effect of immunotoxins.

Risberg K, Guldvik IJ, Palchaudhuri R, Xi Y, Ju J, Fodstad O, Hergenrother PJ, Andersson Y.

J Immunother. 2011 Jun;34(5):438-47. doi: 10.1097/CJI.0b013e31821e00ae.

PMID:
21577141
40.

B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation.

Liu H, Tekle C, Chen YW, Kristian A, Zhao Y, Zhou M, Liu Z, Ding Y, Wang B, Mælandsmo GM, Nesland JM, Fodstad O, Tan M.

Mol Cancer Ther. 2011 Jun;10(6):960-71. doi: 10.1158/1535-7163.MCT-11-0072. Epub 2011 Apr 25.

41.

Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.

Zhao Y, Liu H, Liu Z, Ding Y, Ledoux SP, Wilson GL, Voellmy R, Lin Y, Lin W, Nahta R, Liu B, Fodstad O, Chen J, Wu Y, Price JE, Tan M.

Cancer Res. 2011 Jul 1;71(13):4585-97. doi: 10.1158/0008-5472.CAN-11-0127. Epub 2011 Apr 15.

42.

Disseminated tumour cells as a prognostic biomarker in colorectal cancer.

Flatmark K, Borgen E, Nesland JM, Rasmussen H, Johannessen HO, Bukholm I, Rosales R, Hårklau L, Jacobsen HJ, Sandstad B, Boye K, Fodstad Ø.

Br J Cancer. 2011 Apr 26;104(9):1434-9. doi: 10.1038/bjc.2011.97. Epub 2011 Mar 29.

43.

Systematic evaluation of three microRNA profiling platforms: microarray, beads array, and quantitative real-time PCR array.

Wang B, Howel P, Bruheim S, Ju J, Owen LB, Fodstad O, Xi Y.

PLoS One. 2011 Feb 11;6(2):e17167. doi: 10.1371/journal.pone.0017167.

44.

Antitumour activity of oral E7080, a novel inhibitor of multiple tyrosine kinases, in human sarcoma xenografts.

Bruheim S, Kristian A, Uenaka T, Suo Z, Tsuruoka A, Nesland JM, Fodstad Ø.

Int J Cancer. 2011 Aug 1;129(3):742-50. doi: 10.1002/ijc.25922. Epub 2011 Mar 25.

45.

Emerging metabolic targets in cancer therapy.

Zhao Y, Liu H, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M.

Front Biosci (Landmark Ed). 2011 Jan 1;16:1844-60. Review.

46.

MicroRNAs as biomarkers in colorectal cancer.

Schee K, Fodstad Ø, Flatmark K.

Am J Pathol. 2010 Oct;177(4):1592-9. doi: 10.2353/ajpath.2010.100024. Epub 2010 Sep 9. Review.

47.

A novel human recombinant single-chain antibody targeting CD166/ALCAM inhibits cancer cell invasion in vitro and in vivo tumour growth.

Wiiger MT, Gehrken HB, Fodstad Ø, Maelandsmo GM, Andersson Y.

Cancer Immunol Immunother. 2010 Nov;59(11):1665-74. doi: 10.1007/s00262-010-0892-3. Epub 2010 Jul 16.

48.

MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.

Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M.

J Biol Chem. 2010 Jul 9;285(28):21496-507. doi: 10.1074/jbc.M109.083337. Epub 2010 May 11.

49.

Anti-melanoma activity of the 9.2.27PE immunotoxin in dacarbazine resistant cells.

Risberg K, Fodstad O, Andersson Y.

J Immunother. 2010 Apr;33(3):272-8. doi: 10.1097/CJI.0b013e3181c54991.

PMID:
20445347
50.

The transcript expression and protein distribution pattern in human colorectal carcinoma reveal a pivotal role of COM-1/p8 as a tumour suppressor.

Davies ML, Parr C, Sanders AJ, Fodstad O, Jiang WG.

Cancer Genomics Proteomics. 2010 Mar-Apr;7(2):75-80.

PMID:
20335521

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