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Items: 1 to 50 of 58

1.

Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.

Rieblinger B, Fischer K, Kind A, Saller BS, Baars W, Schuster M, Wolf-van Buerck L, Schäffler A, Flisikowska T, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Wolf E, Seissler J, Schwinzer R, Schnieke A.

Xenotransplantation. 2018 Mar;25(2):e12382. doi: 10.1111/xen.12382. Epub 2018 Jan 23.

PMID:
29359453
2.

Altered microRNA profiles during early colon adenoma progression in a porcine model of familial adenomatous polyposis.

Stachowiak M, Flisikowska T, Bauersachs S, Perleberg C, Pausch H, Switonski M, Kind A, Saur D, Schnieke A, Flisikowski K.

Oncotarget. 2017 Oct 10;8(56):96154-96160. doi: 10.18632/oncotarget.21774. eCollection 2017 Nov 10.

3.

Rapid Discovery of De Novo Deleterious Mutations in Cattle Enhances the Value of Livestock as Model Species.

Bourneuf E, Otz P, Pausch H, Jagannathan V, Michot P, Grohs C, Piton G, Ammermüller S, Deloche MC, Fritz S, Leclerc H, Péchoux C, Boukadiri A, Hozé C, Saintilan R, Créchet F, Mosca M, Segelke D, Guillaume F, Bouet S, Baur A, Vasilescu A, Genestout L, Thomas A, Allais-Bonnet A, Rocha D, Colle MA, Klopp C, Esquerré D, Wurmser C, Flisikowski K, Schwarzenbacher H, Burgstaller J, Brügmann M, Dietschi E, Rudolph N, Freick M, Barbey S, Fayolle G, Danchin-Burge C, Schibler L, Bed'Hom B, Hayes BJ, Daetwyler HD, Fries R, Boichard D, Pin D, Drögemüller C, Capitan A.

Sci Rep. 2017 Sep 13;7(1):11466. doi: 10.1038/s41598-017-11523-3.

4.

Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression.

Flisikowska T, Stachowiak M, Xu H, Wagner A, Hernandez-Caceres A, Wurmser C, Perleberg C, Pausch H, Perkowska A, Fischer K, Frishman D, Fries R, Switonski M, Kind A, Saur D, Schnieke A, Flisikowski K.

Sci Rep. 2017 Jul 26;7(1):6613. doi: 10.1038/s41598-017-06741-8.

5.

Maternal placenta modulates a deleterious fetal mutation.

Xu H, Pausch H, Venhoranta H, Rutkowska K, Wurmser C, Rieblinger B, Flisikowska T, Frishman D, Zwierzchowski L, Fries R, Andersson M, Kind A, Schnieke A, Flisikowski K.

Biol Reprod. 2017 Aug 1;97(2):249-257. doi: 10.1093/biolre/iox064.

PMID:
28679164
6.

Methylation Patterns of SOX3, SOX9, and WNT4 Genes in Gonads of Dogs with XX (SRY-Negative) Disorder of Sexual Development.

Salamon S, Flisikowski K, Switonski M.

Sex Dev. 2017;11(2):86-93. doi: 10.1159/000466712. Epub 2017 Apr 1.

PMID:
28365713
7.

Deep sequencing of a candidate region harboring the SOX9 gene for the canine XX disorder of sex development.

Nowacka-Woszuk J, Szczerbal I, Pausch H, Hundi S, Hytönen MK, Grzemski A, Flisikowski K, Lohi H, Switonski M, Szydlowski M.

Anim Genet. 2017 Jun;48(3):330-337. doi: 10.1111/age.12538. Epub 2017 Jan 17.

PMID:
28094446
8.

Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.

Fischer K, Kraner-Scheiber S, Petersen B, Rieblinger B, Buermann A, Flisikowska T, Flisikowski K, Christan S, Edlinger M, Baars W, Kurome M, Zakhartchenko V, Kessler B, Plotzki E, Szczerbal I, Switonski M, Denner J, Wolf E, Schwinzer R, Niemann H, Kind A, Schnieke A.

Sci Rep. 2016 Jun 29;6:29081. doi: 10.1038/srep29081.

9.

Non-invasive assessment of porcine oocyte quality by supravital staining of cumulus-oocyte complexes with lissamine green B.

Dutta R, Li S, Fischer K, Kind A, Flisikowska T, Flisikowski K, Rottmann O, Schnieke A.

Zygote. 2016 Jun;24(3):418-27. doi: 10.1017/S0967199415000349.

PMID:
27172057
10.

A frameshift mutation in GON4L is associated with proportionate dwarfism in Fleckvieh cattle.

Schwarzenbacher H, Wurmser C, Flisikowski K, Misurova L, Jung S, Langenmayer MC, Schnieke A, Knubben-Schweizer G, Fries R, Pausch H.

Genet Sel Evol. 2016 Mar 31;48:25. doi: 10.1186/s12711-016-0207-z.

11.

A porcine model of osteosarcoma.

Saalfrank A, Janssen KP, Ravon M, Flisikowski K, Eser S, Steiger K, Flisikowska T, Müller-Fliedner P, Schulze É, Brönner C, Gnann A, Kappe E, Böhm B, Schade B, Certa U, Saur D, Esposito I, Kind A, Schnieke A.

Oncogenesis. 2016 Mar 14;5:e210. doi: 10.1038/oncsis.2016.19.

12.

Germline gene polymorphisms predisposing domestic mammals to carcinogenesis.

Flisikowski K, Flisikowska T, Sikorska A, Perkowska A, Kind A, Schnieke A, Switonski M.

Vet Comp Oncol. 2017 Jun;15(2):289-298. doi: 10.1111/vco.12186. Epub 2015 Nov 17. Review.

PMID:
26575426
13.

PEG3 domain gene expression in maternal and foetal placenta in intrauterine growth restricted bovine foetuses.

Li S, Pausch H, Venhoranta H, Adamowicz K, Andersson M, Zwierzchowski L, Kind A, Schnieke A, Flisikowski K.

Anim Genet. 2016 Feb;47(1):106-9. doi: 10.1111/age.12373. Epub 2015 Nov 5.

PMID:
26537866
14.

Copy number variation in the region harboring SOX9 gene in dogs with testicular/ovotesticular disorder of sex development (78,XX; SRY-negative).

Marcinkowska-Swojak M, Szczerbal I, Pausch H, Nowacka-Woszuk J, Flisikowski K, Dzimira S, Nizanski W, Payan-Carreira R, Fries R, Kozlowski P, Switonski M.

Sci Rep. 2015 Oct 1;5:14696. doi: 10.1038/srep14696.

15.

Homozygous haplotype deficiency reveals deleterious mutations compromising reproductive and rearing success in cattle.

Pausch H, Schwarzenbacher H, Burgstaller J, Flisikowski K, Wurmser C, Jansen S, Jung S, Schnieke A, Wittek T, Fries R.

BMC Genomics. 2015 Apr 18;16:312. doi: 10.1186/s12864-015-1483-7.

16.

Viable pigs with a conditionally-activated oncogenic KRAS mutation.

Li S, Edlinger M, Saalfrank A, Flisikowski K, Tschukes A, Kurome M, Zakhartchenko V, Kessler B, Saur D, Kind A, Wolf E, Schnieke A, Flisikowska T.

Transgenic Res. 2015 Jun;24(3):509-17. doi: 10.1007/s11248-015-9866-8. Epub 2015 Feb 26.

PMID:
25716163
17.

In frame exon skipping in UBE3B is associated with developmental disorders and increased mortality in cattle.

Venhoranta H, Pausch H, Flisikowski K, Wurmser C, Taponen J, Rautala H, Kind A, Schnieke A, Fries R, Lohi H, Andersson M.

BMC Genomics. 2014 Oct 12;15:890. doi: 10.1186/1471-2164-15-890.

18.

Dual fluorescent reporter pig for Cre recombination: transgene placement at the ROSA26 locus.

Li S, Flisikowska T, Kurome M, Zakhartchenko V, Kessler B, Saur D, Kind A, Wolf E, Flisikowski K, Schnieke A.

PLoS One. 2014 Jul 15;9(7):e102455. doi: 10.1371/journal.pone.0102455. eCollection 2014.

19.

Polymorphism in 3' untranslated region of the pig PPARA gene influences its transcript level and is associated with adipose tissue accumulation.

Stachowiak M, Szydlowski M, Flisikowski K, Flisikowska T, Bartz M, Schnieke A, Switonski M.

J Anim Sci. 2014 Jun;92(6):2363-71. doi: 10.2527/jas.2013-7509. Epub 2014 Mar 26.

PMID:
24671595
20.

Non-CpG hypermethylation in placenta of mutation-induced intrauterine growth restricted bovine foetuses.

Venhoranta H, Li S, Salamon S, Flisikowska T, Andersson M, Switonski M, Kind A, Schnieke A, Flisikowski K.

Biochem Biophys Res Commun. 2014 Feb 14;444(3):391-4. doi: 10.1016/j.bbrc.2014.01.071. Epub 2014 Jan 27.

PMID:
24480436
21.

Ectopic KIT copy number variation underlies impaired migration of primordial germ cells associated with gonadal hypoplasia in cattle (Bos taurus).

Venhoranta H, Pausch H, Wysocki M, Szczerbal I, Hänninen R, Taponen J, Uimari P, Flisikowski K, Lohi H, Fries R, Switonski M, Andersson M.

PLoS One. 2013 Sep 26;8(9):e75659. doi: 10.1371/journal.pone.0075659. eCollection 2013.

22.

Expression pattern of STAT5A gene during early bovine embryogenesis.

Flisikowski K, Boulhaeve M, Lopes FP, Wolf E, Zwierzchowski L.

Zygote. 2015 Apr;23(2):307-11. doi: 10.1017/S0967199413000427. Epub 2013 Aug 28.

PMID:
23981721
23.

Fetal growth restriction caused by MIMT1 deletion alters brain transcriptome in cattle.

Venhoranta H, Bauersachs S, Taponen J, Lohi H, Taira T, Andersson M, Kind A, Schnieke A, Flisikowski K.

Int J Dev Neurosci. 2013 Nov;31(7):463-7. doi: 10.1016/j.ijdevneu.2013.05.003. Epub 2013 May 29.

PMID:
23726833
24.

Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set.

Kurome M, Geistlinger L, Kessler B, Zakhartchenko V, Klymiuk N, Wuensch A, Richter A, Baehr A, Kraehe K, Burkhardt K, Flisikowski K, Flisikowska T, Merkl C, Landmann M, Durkovic M, Tschukes A, Kraner S, Schindelhauer D, Petri T, Kind A, Nagashima H, Schnieke A, Zimmer R, Wolf E.

BMC Biotechnol. 2013 May 20;13:43. doi: 10.1186/1472-6750-13-43.

25.

Truncation of MIMT1 gene in the PEG3 domain leads to major changes in placental gene expression and stillbirth in cattle.

Flisikowski K, Venhoranta H, Bauersachs S, Hänninen R, Fürst RW, Saalfrank A, Ulbrich SE, Taponen J, Lohi H, Wolf E, Kind A, Andersson M, Schnieke A.

Biol Reprod. 2012 Dec 21;87(6):140. doi: 10.1095/biolreprod.112.104240. Print 2012 Jun.

PMID:
23100617
26.

Inactivation and inducible oncogenic mutation of p53 in gene targeted pigs.

Leuchs S, Saalfrank A, Merkl C, Flisikowska T, Edlinger M, Durkovic M, Rezaei N, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Kind A, Wolf E, Schnieke A.

PLoS One. 2012;7(10):e43323. doi: 10.1371/journal.pone.0043323. Epub 2012 Oct 5.

27.

Polymorphisms in the promoter region of the adiponectin (ADIPOQ) gene are presumably associated with transcription level and carcass traits in pigs.

Cieslak J, Flisikowska T, Schnieke A, Kind A, Szydlowski M, Switonski M, Flisikowski K.

Anim Genet. 2013 Jun;44(3):340-3. doi: 10.1111/j.1365-2052.2012.02397.x. Epub 2012 Jul 20.

PMID:
22812639
28.

Effects of new polymorphisms in the bovine myocyte enhancer factor 2D (MEF2D) gene on the expression rates of the longissimus dorsi muscle.

Juszczuk-Kubiak E, Starzyński RR, Sakowski T, Wicińska K, Flisikowski K.

Mol Biol Rep. 2012 Aug;39(8):8387-93. doi: 10.1007/s11033-012-1689-6. Epub 2012 Jun 20.

29.

Polymorphic variants within a putative upstream open reading frame of the MC4R gene do not affect body weight of farmed red foxes.

Nowacka-Woszuk J, Skorczyk A, Flisikowski K, Szydlowski M, Switonski M.

Anim Genet. 2012 Aug;43(4):480-1. doi: 10.1111/j.1365-2052.2011.02279.x. Epub 2011 Oct 21. No abstract available.

PMID:
22497488
30.

Promoter variant-dependent mRNA expression of the MEF2A in longissimus dorsi muscle in cattle.

Juszczuk-Kubiak E, Starzyński RR, Wicińska K, Flisikowski K.

DNA Cell Biol. 2012 Jun;31(6):1131-5. doi: 10.1089/dna.2011.1533. Epub 2012 Feb 9.

31.

Combining evidence of selection with association analysis increases power to detect regions influencing complex traits in dairy cattle.

Schwarzenbacher H, Dolezal M, Flisikowski K, Seefried F, Wurmser C, Schlötterer C, Fries R.

BMC Genomics. 2012 Jan 30;13:48. doi: 10.1186/1471-2164-13-48.

32.

A comparative analysis of MC4R gene sequence, polymorphism, and chromosomal localization in Chinese raccoon dog and Arctic fox.

Skorczyk A, Flisikowski K, Switonski M.

DNA Cell Biol. 2012 May;31(5):732-8. doi: 10.1089/dna.2011.1423. Epub 2011 Nov 2.

PMID:
22047079
33.

A novel mutation in the maternally imprinted PEG3 domain results in a loss of MIMT1 expression and causes abortions and stillbirths in cattle (Bos taurus).

Flisikowski K, Venhoranta H, Nowacka-Woszuk J, McKay SD, Flyckt A, Taponen J, Schnabel R, Schwarzenbacher H, Szczerbal I, Lohi H, Fries R, Taylor JF, Switonski M, Andersson M.

PLoS One. 2010 Nov 30;5(11):e15116. doi: 10.1371/journal.pone.0015116.

34.

Genome-wide association study identifies two major loci affecting calving ease and growth-related traits in cattle.

Pausch H, Flisikowski K, Jung S, Emmerling R, Edel C, Götz KU, Fries R.

Genetics. 2011 Jan;187(1):289-97. doi: 10.1534/genetics.110.124057. Epub 2010 Nov 8.

35.

Nucleotide sequence and variations of the bovine myocyte enhancer factor 2C (MEF2C) gene promoter in Bos taurus cattle.

Juszczuk-Kubiak E, Flisikowski K, Wicińska K.

Mol Biol Rep. 2011 Feb;38(2):1269-76. doi: 10.1007/s11033-010-0226-8. Epub 2010 Jun 29.

36.

Association of MC3R gene polymorphisms with body weight in the red fox and comparative gene organization in four canids.

Skorczyk A, Flisikowski K, Szydlowski M, Cieslak J, Fries R, Switonski M.

Anim Genet. 2011 Feb;42(1):104-7. doi: 10.1111/j.1365-2052.2010.02075.x.

PMID:
20477806
37.

Characterization of the porcine AMPK alpha 2 catalytic subunitgene (PRKAA2): genomic structure, polymorphism detection and association study.

Lin L, Flisikowski K, Schwarzenbacher H, Scharfe M, Severitt S, Blöcker H, Fries R.

Anim Genet. 2010 Apr;41(2):203-7. doi: 10.1111/j.1365-2052.2009.01971.x. Epub 2009 Sep 29.

PMID:
19793316
38.

Association of polymorphisms in exons 2 and 10 of the insulin-like growth factor 2 ( IGF2) gene with milk production traits in Polish Holstein-Friesian cattle.

Bagnicka E, Siadkowska E, Strzałkowska N, Zelazowska B, Flisikowski K, Krzyzewski J, Zwierzchowski L.

J Dairy Res. 2010 Feb;77(1):37-42. doi: 10.1017/S0022029909990197. Epub 2009 Sep 29.

PMID:
19785908
39.

Postnatal transcription profile and polymorphism of the ADIPOR1 gene in five pig breeds.

Stachowiak M, Flisikowski K, Szydlowski M, Fries R, Switonski M.

Anim Genet. 2010 Feb;41(1):97-100. doi: 10.1111/j.1365-2052.2009.01958.x. Epub 2009 Sep 24.

PMID:
19781036
40.

Dissection of genetic factors modulating fetal growth in cattle indicates a substantial role of the non-SMC condensin I complex, subunit G (NCAPG) gene.

Eberlein A, Takasuga A, Setoguchi K, Pfuhl R, Flisikowski K, Fries R, Klopp N, Fürbass R, Weikard R, Kühn C.

Genetics. 2009 Nov;183(3):951-64. doi: 10.1534/genetics.109.106476. Epub 2009 Aug 31.

41.

Whole genome sequencing of a single Bos taurus animal for single nucleotide polymorphism discovery.

Eck SH, Benet-Pagès A, Flisikowski K, Meitinger T, Fries R, Strom TM.

Genome Biol. 2009;10(8):R82. doi: 10.1186/gb-2009-10-8-r82. Epub 2009 Aug 6.

42.

A new SNP in the 3'UTR region of the bovine calpain small subunit (CAPNS1) gene.

Juszczuk-Kubiak E, Flisikowski K, Wicińska K.

Mol Biol Rep. 2010 Jan;37(1):473-6. doi: 10.1007/s11033-009-9654-8. Epub 2009 Aug 2.

PMID:
19649723
43.

Identification of the new polymorphisms in the promoter region of the CAST gene in cattle.

Juszczuk-Kubiak E, Flisikowski K, Wicińska K, Połoszynowicz J, Rosochacki S.

Meat Sci. 2009 Jun;82(2):278-83. doi: 10.1016/j.meatsci.2009.01.001. Epub 2009 Jan 9.

PMID:
20416736
44.

Variation in neighbouring genes of the dopaminergic and serotonergic systems affects feather pecking behaviour of laying hens.

Flisikowski K, Schwarzenbacher H, Wysocki M, Weigend S, Preisinger R, Kjaer JB, Fries R.

Anim Genet. 2009 Apr;40(2):192-9. doi: 10.1111/j.1365-2052.2008.01821.x. Epub 2008 Dec 18.

PMID:
19120086
45.

Effect of new SNP within bovine prolactin gene enhancer region on expression in the pituitary gland.

Brym P, Malewski T, Starzyński R, Flisikowski K, Wójcik E, Ruść A, Zwierzchowski L, Kamiński S.

Biochem Genet. 2007 Oct;45(9-10):743-54. Epub 2007 Oct 11.

PMID:
17929163
46.

The polymorphism in the beta4-defensin gene and its association with production and somatic cell count in Holstein-Friesian cows.

Bagnicka E, Strzałkowska N, Flisikowski K, Szreder T, Jóźwik A, Prusak B, Krzyzewski J, Zwierzchowski L.

J Anim Breed Genet. 2007 Jun;124(3):150-6.

PMID:
17550357
47.

Cytogenetic mapping of DGAT1, PPARA, ADIPOR1 and CREB genes in the pig.

Szczerbal I, Lin L, Stachowiak M, Chmurzynska A, Mackowski M, Winter A, Flisikowski K, Fries R, Switonski M.

J Appl Genet. 2007;48(1):73-6.

PMID:
17272864
48.

An InDel polymorphism in exon 6 of IGF2 associated with the breeding value of Polish Holstein-Friesian bulls.

Flisikowski K, Adamowicz T, Strabel T, Jankowski T, Switonski M, Zwierzchowski L.

Biochem Genet. 2007 Feb;45(1-2):139-43. No abstract available.

PMID:
17242995
49.

Polymorphisms in coding and regulatory regions of the porcine MYF6 and MYOG genes and expression of the MYF6 gene in m. longissimus dorsi versus productive traits in pigs.

Wyszyńska-Koko J, Pierzchała M, Flisikowski K, Kamyczek M, Rózycki M, Kurył J.

J Appl Genet. 2006;47(2):131-8.

PMID:
16682754
50.

A new SNP in the promoter region of the porcine MYF5 gene has no effect on its transcript level in m. longissimus dorsi.

Urbański P, Flisikowski K, Starzyński RR, Kurył J, Kamyczek M.

J Appl Genet. 2006;47(1):59-61.

PMID:
16424610

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