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Items: 1 to 50 of 91

1.

Transient external force induces phenotypic reversion of malignant epithelial structures via nitric oxide signaling.

Ricca BL, Venugopalan G, Furuta S, Tanner K, Orellana WA, Reber CD, Brownfield DG, Bissell MJ, Fletcher DA.

Elife. 2018 Mar 21;7. pii: e26161. doi: 10.7554/eLife.26161.

2.

WH2 and proline-rich domains of WASP-family proteins collaborate to accelerate actin filament elongation.

Bieling P, Hansen SD, Akin O, Li TD, Hayden CC, Fletcher DA, Mullins RD.

EMBO J. 2018 Jan 4;37(1):102-121. doi: 10.15252/embj.201797039. Epub 2017 Nov 15.

3.

A Test-and-Not-Treat Strategy for Onchocerciasis in Loa loa-Endemic Areas.

Kamgno J, Pion SD, Chesnais CB, Bakalar MH, D'Ambrosio MV, Mackenzie CD, Nana-Djeunga HC, Gounoue-Kamkumo R, Njitchouang GR, Nwane P, Tchatchueng-Mbouga JB, Wanji S, Stolk WA, Fletcher DA, Klion AD, Nutman TB, Boussinesq M.

N Engl J Med. 2017 Nov 23;377(21):2044-2052. doi: 10.1056/NEJMoa1705026. Epub 2017 Nov 8.

4.

Force-induced transcellular tunnel formation in endothelial cells.

Ng WP, Webster KD, Stefani C, Schmid EM, Lemichez E, Bassereau P, Fletcher DA.

Mol Biol Cell. 2017 Aug 9. pii: mbc.E17-01-0080. doi: 10.1091/mbc.E17-01-0080. [Epub ahead of print]

5.

Organ sculpting by patterned extracellular matrix stiffness.

Crest J, Diz-Muñoz A, Chen DY, Fletcher DA, Bilder D.

Elife. 2017 Jun 27;6. pii: e24958. doi: 10.7554/eLife.24958.

6.

Size-dependent protein segregation at membrane interfaces.

Schmid EM, Bakalar MH, Choudhuri K, Weichsel J, Ann H, Geissler PL, Dustin ML, Fletcher DA.

Nat Phys. 2016 Jul;12(7):704-711. Epub 2016 Mar 7.

7.

Bottom-Up Biology: Harnessing Engineering to Understand Nature.

Fletcher DA.

Dev Cell. 2016 Sep 26;38(6):587-9. doi: 10.1016/j.devcel.2016.09.009.

8.

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM.

Varshney D, Petit AP, Bueren-Calabuig JA, Jansen C, Fletcher DA, Peggie M, Weidlich S, Scullion P, Pisliakov AV, Cowling VH.

Nucleic Acids Res. 2016 Dec 1;44(21):10423-10436. Epub 2016 Jul 15.

9.

Accuracy of Mobile Phone and Handheld Light Microscopy for the Diagnosis of Schistosomiasis and Intestinal Protozoa Infections in Côte d'Ivoire.

Coulibaly JT, Ouattara M, D'Ambrosio MV, Fletcher DA, Keiser J, Utzinger J, N'Goran EK, Andrews JR, Bogoch II.

PLoS Negl Trop Dis. 2016 Jun 27;10(6):e0004768. doi: 10.1371/journal.pntd.0004768. eCollection 2016 Jun.

10.

Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil Migration.

Diz-Muñoz A, Thurley K, Chintamen S, Altschuler SJ, Wu LF, Fletcher DA, Weiner OD.

PLoS Biol. 2016 Jun 9;14(6):e1002474. doi: 10.1371/journal.pbio.1002474. eCollection 2016 Jun.

11.

Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks.

Bieling P, Li TD, Weichsel J, McGorty R, Jreij P, Huang B, Fletcher DA, Mullins RD.

Cell. 2016 Jan 14;164(1-2):115-127. doi: 10.1016/j.cell.2015.11.057.

12.

Evaluation of mobile digital light-emitting diode fluorescence microscopy in Hanoi, Viet Nam.

Chaisson LH, Reber C, Phan H, Switz N, Nilsson LM, Myers F, Nhung NV, Luu L, Pham T, Vu C, Nguyen H, Nguyen A, Dinh T, Nahid P, Fletcher DA, Cattamanchi A.

Int J Tuberc Lung Dis. 2015 Sep;19(9):1068-72. doi: 10.5588/ijtld.15.0018.

PMID:
26260826
13.

Assessment of a Smartphone Otoscope Device for the Diagnosis and Management of Otitis Media.

Rappaport KM, McCracken CC, Beniflah J, Little WK, Fletcher DA, Lam WA, Shane AL.

Clin Pediatr (Phila). 2016 Aug;55(9):800-10. doi: 10.1177/0009922815593909. Epub 2015 Jul 7. No abstract available.

PMID:
26156976
14.

Reconstitution of proteins on electroformed giant unilamellar vesicles.

Schmid EM, Richmond DL, Fletcher DA.

Methods Cell Biol. 2015;128:319-38. doi: 10.1016/bs.mcb.2015.02.004. Epub 2015 Apr 8.

15.

Multi-Contrast Imaging and Digital Refocusing on a Mobile Microscope with a Domed LED Array.

Phillips ZF, D'Ambrosio MV, Tian L, Rulison JJ, Patel HS, Sadras N, Gande AV, Switz NA, Fletcher DA, Waller L.

PLoS One. 2015 May 13;10(5):e0124938. doi: 10.1371/journal.pone.0124938. eCollection 2015.

16.

Point-of-care quantification of blood-borne filarial parasites with a mobile phone microscope.

D'Ambrosio MV, Bakalar M, Bennuru S, Reber C, Skandarajah A, Nilsson L, Switz N, Kamgno J, Pion S, Boussinesq M, Nutman TB, Fletcher DA.

Sci Transl Med. 2015 May 6;7(286):286re4. doi: 10.1126/scitranslmed.aaa3480.

PMID:
25947164
17.

Myosin light chain kinase regulates cell polarization independently of membrane tension or Rho kinase.

Lou SS, Diz-Muñoz A, Weiner OD, Fletcher DA, Theriot JA.

J Cell Biol. 2015 Apr 27;209(2):275-88. doi: 10.1083/jcb.201409001.

18.

Diagnosis of Schistosoma haematobium infection with a mobile phone-mounted Foldscope and a reversed-lens CellScope in Ghana.

Ephraim RK, Duah E, Cybulski JS, Prakash M, D'Ambrosio MV, Fletcher DA, Keiser J, Andrews JR, Bogoch II.

Am J Trop Med Hyg. 2015 Jun;92(6):1253-6. doi: 10.4269/ajtmh.14-0741. Epub 2015 Apr 27.

19.

Mechanical tension drives cell membrane fusion.

Kim JH, Ren Y, Ng WP, Li S, Son S, Kee YS, Zhang S, Zhang G, Fletcher DA, Robinson DN, Chen EH.

Dev Cell. 2015 Mar 9;32(5):561-73. doi: 10.1016/j.devcel.2015.01.005. Epub 2015 Feb 12.

20.

A lateral electrophoretic flow diagnostic assay.

Lin R, Skandarajah A, Gerver RE, Neira HD, Fletcher DA, Herr AE.

Lab Chip. 2015 Mar 21;15(6):1488-96. doi: 10.1039/c4lc01370k.

21.

Multicellular architecture of malignant breast epithelia influences mechanics.

Venugopalan G, Camarillo DB, Webster KD, Reber CD, Sethian JA, Weaver VM, Fletcher DA, El-Samad H, Rycroft CH.

PLoS One. 2014 Aug 11;9(8):e101955. doi: 10.1371/journal.pone.0101955. eCollection 2014.

22.

Novel telemedicine device for diagnosis of corneal abrasions and ulcers in resource-poor settings.

Maamari RN, Ausayakhun S, Margolis TP, Fletcher DA, Keenan JD.

JAMA Ophthalmol. 2014 Jul;132(7):894-5. doi: 10.1001/jamaophthalmol.2014.335. No abstract available.

PMID:
25010172
23.

Tensional homeostasis in single fibroblasts.

Webster KD, Ng WP, Fletcher DA.

Biophys J. 2014 Jul 1;107(1):146-55. doi: 10.1016/j.bpj.2014.04.051.

24.

Low-cost mobile phone microscopy with a reversed mobile phone camera lens.

Switz NA, D'Ambrosio MV, Fletcher DA.

PLoS One. 2014 May 22;9(5):e95330. doi: 10.1371/journal.pone.0095330. eCollection 2014.

25.

Quantitative imaging with a mobile phone microscope.

Skandarajah A, Reber CD, Switz NA, Fletcher DA.

PLoS One. 2014 May 13;9(5):e96906. doi: 10.1371/journal.pone.0096906. eCollection 2014.

26.

Dynamic mechanical responses of Arabidopsis thylakoid membranes during PSII-specific illumination.

Clausen CH, Brooks MD, Li TD, Grob P, Kemalyan G, Nogales E, Niyogi KK, Fletcher DA.

Biophys J. 2014 May 6;106(9):1864-70. doi: 10.1016/j.bpj.2014.03.016.

27.

Lipid bilayer vesicle generation using microfluidic jetting.

Coyne CW, Patel K, Heureaux J, Stachowiak J, Fletcher DA, Liu AP.

J Vis Exp. 2014 Feb 21;(84):e51510. doi: 10.3791/51510.

28.

Micropattern-guided assembly of overlapping pairs of dynamic microtubules.

Fourniol FJ, Li TD, Bieling P, Mullins RD, Fletcher DA, Surrey T.

Methods Enzymol. 2014;540:339-60. doi: 10.1016/B978-0-12-397924-7.00019-4.

29.

The biology of boundary conditions: cellular reconstitution in one, two, and three dimensions.

Vahey MD, Fletcher DA.

Curr Opin Cell Biol. 2014 Feb;26:60-8. doi: 10.1016/j.ceb.2013.10.001. Epub 2013 Nov 12. Review.

30.

Distributing medical expertise: the evolution and impact of telemedicine in arkansas.

Lowery CL, Bronstein JM, Benton TL, Fletcher DA.

Health Aff (Millwood). 2014 Feb;33(2):235-43. doi: 10.1377/hlthaff.2013.1001. Review. Erratum in: Health Aff (Millwood). 2015 Jan;34(1):189.

PMID:
24493766
31.

Placental syncytium forms a biophysical barrier against pathogen invasion.

Zeldovich VB, Clausen CH, Bradford E, Fletcher DA, Maltepe E, Robbins JR, Bakardjiev AI.

PLoS Pathog. 2013;9(12):e1003821. doi: 10.1371/journal.ppat.1003821. Epub 2013 Dec 12.

32.

A mobile phone-based retinal camera for portable wide field imaging.

Maamari RN, Keenan JD, Fletcher DA, Margolis TP.

Br J Ophthalmol. 2014 Apr;98(4):438-41. doi: 10.1136/bjophthalmol-2013-303797. Epub 2013 Dec 16.

PMID:
24344230
33.

Cytoplasmic volume modulates spindle size during embryogenesis.

Good MC, Vahey MD, Skandarajah A, Fletcher DA, Heald R.

Science. 2013 Nov 15;342(6160):856-60. doi: 10.1126/science.1243147.

34.

To pull or be pulled: parsing the multiple modes of mechanotransduction.

Ricca BL, Venugopalan G, Fletcher DA.

Curr Opin Cell Biol. 2013 Oct;25(5):558-64. doi: 10.1016/j.ceb.2013.06.002. Epub 2013 Jul 2. Review.

35.

A multi-structural single cell model of force-induced interactions of cytoskeletal components.

Barreto S, Clausen CH, Perrault CM, Fletcher DA, Lacroix D.

Biomaterials. 2013 Aug;34(26):6119-26. doi: 10.1016/j.biomaterials.2013.04.022. Epub 2013 May 21.

36.

Patterned collagen fibers orient branching mammary epithelium through distinct signaling modules.

Brownfield DG, Venugopalan G, Lo A, Mori H, Tanner K, Fletcher DA, Bissell MJ.

Curr Biol. 2013 Apr 22;23(8):703-9. doi: 10.1016/j.cub.2013.03.032. Epub 2013 Apr 4.

37.

Mobile digital fluorescence microscopy for diagnosis of tuberculosis.

Tapley A, Switz N, Reber C, Davis JL, Miller C, Matovu JB, Worodria W, Huang L, Fletcher DA, Cattamanchi A.

J Clin Microbiol. 2013 Jun;51(6):1774-8. doi: 10.1128/JCM.03432-12. Epub 2013 Apr 3.

38.

Use the force: membrane tension as an organizer of cell shape and motility.

Diz-Muñoz A, Fletcher DA, Weiner OD.

Trends Cell Biol. 2013 Feb;23(2):47-53. doi: 10.1016/j.tcb.2012.09.006. Epub 2012 Nov 2. Review.

39.

Membrane bending by protein-protein crowding.

Stachowiak JC, Schmid EM, Ryan CJ, Ann HS, Sasaki DY, Sherman MB, Geissler PL, Fletcher DA, Hayden CC.

Nat Cell Biol. 2012 Sep;14(9):944-9. doi: 10.1038/ncb2561. Epub 2012 Aug 19.

PMID:
22902598
40.

Contractile equilibration of single cells to step changes in extracellular stiffness.

Crow A, Webster KD, Hohlfeld E, Ng WP, Geissler P, Fletcher DA.

Biophys J. 2012 Feb 8;102(3):443-51. doi: 10.1016/j.bpj.2011.11.4020. Epub 2012 Feb 7.

41.

Actin filament curvature biases branching direction.

Risca VI, Wang EB, Chaudhuri O, Chia JJ, Geissler PL, Fletcher DA.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2913-8. doi: 10.1073/pnas.1114292109. Epub 2012 Jan 30.

42.

In vitro modeling of the microvascular occlusion and thrombosis that occur in hematologic diseases using microfluidic technology.

Tsai M, Kita A, Leach J, Rounsevell R, Huang JN, Moake J, Ware RE, Fletcher DA, Lam WA.

J Clin Invest. 2012 Jan;122(1):408-18. doi: 10.1172/JCI58753. Epub 2011 Dec 12.

43.

Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level.

Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA.

PLoS One. 2011;6(10):e26437. doi: 10.1371/journal.pone.0026437. Epub 2011 Oct 20.

44.

Forming giant vesicles with controlled membrane composition, asymmetry, and contents.

Richmond DL, Schmid EM, Martens S, Stachowiak JC, Liska N, Fletcher DA.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9431-6. doi: 10.1073/pnas.1016410108. Epub 2011 May 18.

45.

To model or not to model?

Fletcher DA.

Mol Biol Cell. 2011 Apr;22(7):909-10. doi: 10.1091/mbc.E11-01-0087.

46.

An AFM-based stiffness clamp for dynamic control of rigidity.

Webster KD, Crow A, Fletcher DA.

PLoS One. 2011 Mar 8;6(3):e17807. doi: 10.1371/journal.pone.0017807.

47.

Single-cell multiplex gene detection and sequencing with microfluidically generated agarose emulsions.

Novak R, Zeng Y, Shuga J, Venugopalan G, Fletcher DA, Smith MT, Mathies RA.

Angew Chem Int Ed Engl. 2011 Jan 10;50(2):390-5. doi: 10.1002/anie.201006089. No abstract available.

48.

Mechanics and contraction dynamics of single platelets and implications for clot stiffening.

Lam WA, Chaudhuri O, Crow A, Webster KD, Li TD, Kita A, Huang J, Fletcher DA.

Nat Mater. 2011 Jan;10(1):61-6. doi: 10.1038/nmat2903. Epub 2010 Dec 5.

49.

On force and function.

Fletcher DA.

Mol Biol Cell. 2010 Nov 15;21(22):3795-6. doi: 10.1091/mbc.E10-06-0538. No abstract available.

50.

Connexin mediated cataract prevention in mice.

Li L, Cheng C, Xia CH, White TW, Fletcher DA, Gong X.

PLoS One. 2010 Sep 9;5(9). pii: e12624. doi: 10.1371/journal.pone.0012624.

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