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Molecular Imaging of Smoke-Induced Changes in Nuclear Factor-Kappa B Expression in Murine Tissues Including the Lung.

Syrkina O, Hales CH, Bonab AA, Hamrahi V, Paul K, Jung WJ, Tompkins RG, Fischman AJ, Carter EA.

J Burn Care Res. 2016 Nov/Dec;37(6):335-342.


Kidney and Liver Injuries After Major Burns in Rats Are Prevented by Resolvin D2.

Inoue Y, Yu YM, Kurihara T, Vasilyev A, Ibrahim A, Oklu R, Zhao G, Nair AV, Brown D, Fischman AJ, Tompkins RG, Irimia D.

Crit Care Med. 2016 May;44(5):e241-52. doi: 10.1097/CCM.0000000000001397.


Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle.

Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu YM, Fischman AJ, Martyn JA, Tompkins RG, Kaneki M.

PLoS One. 2015 Jan 16;10(1):e0116633. doi: 10.1371/journal.pone.0116633. eCollection 2015.


Single hind limb burn injury to mice alters nuclear factor-κB expression and [¹⁸F] 2-fluoro-2-deoxy-D-glucose uptake.

Carter EA, Hamrahi V, Paul K, Bonab AA, Jung W, Tompkins RG, Fischman AJ.

J Burn Care Res. 2014 Nov-Dec;35(6):e373-8. doi: 10.1097/BCR.0000000000000035.


Simvastatin reduces burn injury-induced splenic apoptosis via downregulation of the TNF-α/NF-κB pathway.

Zhao G, Yu YM, Kaneki M, Bonab AA, Tompkins RG, Fischman AJ.

Ann Surg. 2015 May;261(5):1006-12. doi: 10.1097/SLA.0000000000000764.


Membrane potential-dependent uptake of 18F-triphenylphosphonium--a new voltage sensor as an imaging agent for detecting burn-induced apoptosis.

Zhao G, Yu YM, Shoup TM, Elmaleh DR, Bonab AA, Tompkins RG, Fischman AJ.

J Surg Res. 2014 May 15;188(2):473-9. doi: 10.1016/j.jss.2014.01.011. Epub 2014 Jan 11.


Effect of exercise on burn-induced changes in tissue-specific glucose metabolism.

Carter EA, Paul K, Bonab AA, Tompkins RG, Fischman AJ.

J Burn Care Res. 2014 Nov-Dec;35(6):470-3. doi: 10.1097/BCR.0000000000000036.


Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass.

Saeidi N, Meoli L, Nestoridi E, Gupta NK, Kvas S, Kucharczyk J, Bonab AA, Fischman AJ, Yarmush ML, Stylopoulos N.

Science. 2013 Jul 26;341(6144):406-10. doi: 10.1126/science.1235103.


Evaluation of intragastric vs intraperitoneal glucose tolerance tests in the evaluation of insulin resistance in a rodent model of burn injury and glucagon-like polypeptide-1 treatment.

Watada S, Yu YM, Fischman AJ, Kurihara T, Shen CA, Tompkins RG, Fagan S.

J Burn Care Res. 2014 Jan-Feb;35(1):e66-72. doi: 10.1097/BCR.0b013e31828a8ede.


Resolvin D2 restores neutrophil directionality and improves survival after burns.

Kurihara T, Jones CN, Yu YM, Fischman AJ, Watada S, Tompkins RG, Fagan SP, Irimia D.

FASEB J. 2013 Jun;27(6):2270-81. doi: 10.1096/fj.12-219519. Epub 2013 Feb 21.


Potential of 18F-FDG PET toward personalized radiotherapy or chemoradiotherapy in lung cancer.

Choi NC, Chun TT, Niemierko A, Ancukiewicz M, Fidias PM, Kradin RL, Mathisen DJ, Lynch TJ, Fischman AJ.

Eur J Nucl Med Mol Imaging. 2013 Jun;40(6):832-41. doi: 10.1007/s00259-013-2348-4. Epub 2013 Feb 12.


Burn injury-induced IRS-1 degradation in mouse skeletal muscle.

Lu XM, Tompkins R, Fischman A.

Int J Burns Trauma. 2013;3(1):37-48. Epub 2013 Jan 24.


Nitric oxide activates intradomain disulfide bond formation in the kinase loop of Akt1/PKBα after burn injury.

Lu XM, Tompkins RG, Fischman AJ.

Int J Mol Med. 2013 Mar;31(3):740-50. doi: 10.3892/ijmm.2013.1241. Epub 2013 Jan 11.


Simvastatin protects hepatocytes from apoptosis by suppressing the TNF-α/caspase-3 signaling pathway in mice with burn injury.

Zhao G, Yu YM, Kaneki M, Tompkins RG, Fischman AJ.

Ann Surg. 2013 Jun;257(6):1129-36. doi: 10.1097/SLA.0b013e318273fdca.


Functional genomics of attention-deficit/hyperactivity disorder (ADHD) risk alleles on dopamine transporter binding in ADHD and healthy control subjects.

Spencer TJ, Biederman J, Faraone SV, Madras BK, Bonab AA, Dougherty DD, Batchelder H, Clarke A, Fischman AJ.

Biol Psychiatry. 2013 Jul 15;74(2):84-9. doi: 10.1016/j.biopsych.2012.11.010. Epub 2012 Dec 27.


Burn injury differentially alters whole-blood and organ glutathione synthesis rates: An experimental model.

Fei ZW, Young VR, Lu XM, Rhodes AB, Tompkins RG, Fischman AJ, Yu YM.

Burns Trauma. 2013 Sep 18;1(2):87-94. doi: 10.4103/2321-3868.118934. eCollection 2013.


Brown adipose tissue and its modulation by a mitochondria-targeted peptide in rat burn injury-induced hypermetabolism.

Yo K, Yu YM, Zhao G, Bonab AA, Aikawa N, Tompkins RG, Fischman AJ.

Am J Physiol Endocrinol Metab. 2013 Feb 15;304(4):E331-41. doi: 10.1152/ajpendo.00098.2012. Epub 2012 Nov 20.


Combination of radiation and burn injury alters [¹⁸F] 2-fluoro-2-deoxy-D-glucose uptake in mice.

Carter EA, Winter D, Tolman C, Paul K, Hamrahi V, Tompkins RG, Fischman AJ.

J Burn Care Res. 2012 Nov-Dec;33(6):723-30. doi: 10.1097/BCR.0b013e31825d678f.


Imaging C-Fos Gene Expression in Burns Using Lipid Coated Spion Nanoparticles.

Papagiannaros A, Righi V, Day GG, Rahme LG, Liu PK, Fischman AJ, Tompkins RG, Tzika AA.

Adv J Mol Imaging. 2012 Oct;2(4):31-37.


Previous burn injury predisposes mice to lipopolysaccharide-induced changes in glucose metabolism.

Carter EA, Paul KW, Barrow SA, Fischman AJ, Tompkins RG.

J Burn Care Res. 2012 Sep-Oct;33(5):683-9. doi: 10.1097/BCR.0b013e31825d6a86.


Gram-negative bacterial infection in thigh abscess can migrate to distant burn depending on burn depth.

Hamrahi V, Hamblin MR, Jung W, Benjamin JB, Paul KW, Fischman AJ, Tompkins RG, Carter EA.

Interdiscip Perspect Infect Dis. 2012;2012:567140. doi: 10.1155/2012/567140. Epub 2012 Jul 26.


Isolation rearing significantly perturbs brain metabolism in the thalamus and hippocampus.

Bonab AA, Fricchione JG, Gorantla S, Vitalo AG, Auster ME, Levine SJ, Scichilone JM, Hegde M, Foote W, Fricchione GL, Denninger JW, Yarmush DM, Fischman AJ, Yarmush ML, Levine JB.

Neuroscience. 2012 Oct 25;223:457-64. doi: 10.1016/j.neuroscience.2012.07.032. Epub 2012 Jul 24.


5-HT2 receptor distribution shown by [18F] setoperone PET in high-functioning autistic adults.

Beversdorf DQ, Nordgren RE, Bonab AA, Fischman AJ, Weise SB, Dougherty DD, Felopulos GJ, Zhou FC, Bauman ML.

J Neuropsychiatry Clin Neurosci. 2012 Spring;24(2):191-7. doi: 10.1176/appi.neuropsych.11080202.


Striatal dopamine transporter binding in adults with ADHD.

Spencer TJ, Madras BK, Fischman AJ, Krause J, La Fougère C.

Am J Psychiatry. 2012 Jun;169(6):665; author reply 666. doi: 10.1176/appi.ajp.2012.12020232. No abstract available.


Investigation of intrathecal transport of NPT002, a prospective therapeutic based on phage M13, in nonhuman primates.

Papisov MI, Belov V, Belova E, Fischman AJ, Fisher R, Wright JL, Gannon KS, Titus J, Gagne M, Gillooly CA.

Drug Deliv Transl Res. 2012 Jun;2(3):210-21. doi: 10.1007/s13346-012-0074-2.


Delivery of proteins to CNS as seen and measured by positron emission tomography.

Papisov MI, Belov V, Fischman AJ, Belova E, Titus J, Gagne M, Gillooly C.

Drug Deliv Transl Res. 2012 Jun;2(3):201-9. doi: 10.1007/s13346-012-0073-3.


In vivo molecular imaging of murine embryonic stem cells delivered to a burn wound surface via Integra® scaffolding.

Hamrahi VF, Goverman J, Jung W, Wu JC, Fischman AJ, Tompkins RG, Yu YY, Fagan SP, Carter EA.

J Burn Care Res. 2012 Mar-Apr;33(2):e49-54. doi: 10.1097/BCR.0b013e3182331d1c.


Glucose metabolism during the early "flow phase" after burn injury.

Xu H, Yu YM, Ma H, Carter EA, Fagan S, Tompkins RG, Fischman AJ.

J Surg Res. 2013 Jan;179(1):e83-90. doi: 10.1016/j.jss.2012.02.037. Epub 2012 Mar 10.


CNS penetration of intrathecal-lumbar idursulfase in the monkey, dog and mouse: implications for neurological outcomes of lysosomal storage disorder.

Calias P, Papisov M, Pan J, Savioli N, Belov V, Huang Y, Lotterhand J, Alessandrini M, Liu N, Fischman AJ, Powell JL, Heartlein MW.

PLoS One. 2012;7(1):e30341. doi: 10.1371/journal.pone.0030341. Epub 2012 Jan 18.


SILAM for quantitative proteomics of liver Akt1/PKBα after burn injury.

Lu XM, Tompkins RG, Fischman AJ.

Int J Mol Med. 2012 Mar;29(3):461-71. doi: 10.3892/ijmm.2011.861. Epub 2011 Dec 14.


Understanding the central pharmacokinetics of spheroidal oral drug absorption system (SODAS) dexmethylphenidate: a positron emission tomography study of dopamine transporter receptor occupancy measured with C-11 altropane.

Spencer TJ, Bonab AA, Dougherty DD, Mirto T, Martin J, Clarke A, Fischman AJ.

J Clin Psychiatry. 2012 Mar;73(3):346-52. doi: 10.4088/JCP.10m06393. Epub 2011 Nov 1.


Association of heat production with 18F-FDG accumulation in murine brown adipose tissue after stress.

Carter EA, Bonab AA, Paul K, Yerxa J, Tompkins RG, Fischman AJ.

J Nucl Med. 2011 Oct;52(10):1616-20. doi: 10.2967/jnumed.111.090175. Epub 2011 Sep 13.


Farnesyltransferase inhibitor FTI-277 reduces mortality of septic mice along with improved bacterial clearance.

Yang W, Yamada M, Tamura Y, Chang K, Mao J, Zou L, Feng Y, Kida K, Scherrer-Crosbie M, Chao W, Ichinose F, Yu YM, Fischman AJ, Tompkins RG, Yao S, Kaneki M.

J Pharmacol Exp Ther. 2011 Dec;339(3):832-41. doi: 10.1124/jpet.111.183558. Epub 2011 Aug 26.


Evaluation of the antioxidant peptide SS31 for treatment of burn-induced insulin resistance.

Carter EA, Bonab AA, Goverman J, Paul K, Yerxa J, Tompkins RG, Fischman AJ.

Int J Mol Med. 2011 Oct;28(4):589-94. doi: 10.3892/ijmm.2011.752. Epub 2011 Jul 19.


Decreased regional cerebral blood flow in medial prefrontal cortex during trauma-unrelated stressful imagery in Vietnam veterans with post-traumatic stress disorder.

Gold AL, Shin LM, Orr SP, Carson MA, Rauch SL, Macklin ML, Lasko NB, Metzger LJ, Dougherty DD, Alpert NM, Fischman AJ, Pitman RK.

Psychol Med. 2011 Dec;41(12):2563-72. doi: 10.1017/S0033291711000730. Epub 2011 May 13.


Effects of burn injury, cold stress and cutaneous wound injury on the morphology and energy metabolism of murine brown adipose tissue (BAT) in vivo.

Carter EA, Bonab AA, Hamrahi V, Pitman J, Winter D, Macintosh LJ, Cyr EM, Paul K, Yerxa J, Jung W, Tompkins RG, Fischman AJ.

Life Sci. 2011 Jul 18;89(3-4):78-85. doi: 10.1016/j.lfs.2011.04.014. Epub 2011 May 4.


Iodine-124 as a label for pharmacological PET imaging.

Belov VV, Bonab AA, Fischman AJ, Heartlein M, Calias P, Papisov MI.

Mol Pharm. 2011 Jun 6;8(3):736-47. doi: 10.1021/mp100358f. Epub 2011 Apr 6.


Effects of glucagon-like peptide 1 on glycemia control and its metabolic consequence after severe thermal injury--studies in an animal model.

Shen CA, Fagan S, Fischman AJ, Carter EE, Chai JK, Lu XM, Yu YM, Tompkins RG.

Surgery. 2011 May;149(5):635-44. doi: 10.1016/j.surg.2010.11.017. Epub 2011 Feb 5.


Simvastatin treatment improves survival in a murine model of burn sepsis: Role of interleukin 6.

Beffa DC, Fischman AJ, Fagan SP, Hamrahi VF, Paul KW, Kaneki M, Yu YM, Tompkins RG, Carter EA.

Burns. 2011 Mar;37(2):222-6. doi: 10.1016/j.burns.2010.10.010. Epub 2010 Dec 8.


A positron emission tomography study examining the dopaminergic activity of armodafinil in adults using [¹¹C]altropane and [¹¹C]raclopride.

Spencer TJ, Madras BK, Bonab AA, Dougherty DD, Clarke A, Mirto T, Martin J, Fischman AJ.

Biol Psychiatry. 2010 Nov 15;68(10):964-70. doi: 10.1016/j.biopsych.2010.08.026.


Effect of simvastatin on burn-induced alterations in tissue specific glucose metabolism: implications for burn associated insulin resistance.

Bonab AA, Carter EA, Paul K, Kaneki M, Yu YM, Tompkins RG, Fischman AJ.

Int J Mol Med. 2010 Sep;26(3):311-6.


Evaluation of (4-[18F]Fluorophenyl)triphenylphosphonium ion. A potential myocardial blood flow agent for PET.

Shoup TM, Elmaleh DR, Brownell AL, Zhu A, Guerrero JL, Fischman AJ.

Mol Imaging Biol. 2011 Jun;13(3):511-517. doi: 10.1007/s11307-010-0349-2.


A PET study examining pharmacokinetics and dopamine transporter occupancy of two long-acting formulations of methylphenidate in adults.

Spencer TJ, Bonab AA, Dougherty DD, Martin J, McDonnell T, Fischman AJ.

Int J Mol Med. 2010 Feb;25(2):261-5.


Resting metabolic activity in the cingulate cortex and vulnerability to posttraumatic stress disorder.

Shin LM, Lasko NB, Macklin ML, Karpf RD, Milad MR, Orr SP, Goetz JM, Fischman AJ, Rauch SL, Pitman RK.

Arch Gen Psychiatry. 2009 Oct;66(10):1099-107. doi: 10.1001/archgenpsychiatry.2009.138.


Evaluation of the effects of oral water and low-density barium sulphate suspension on bowel appearance on FDG-PET/CT.

Blake MA, Setty BN, Cronin CG, Kalra M, Holalkere NS, Fischman AJ, Mueller PR, Sahani DV.

Eur Radiol. 2010 Jan;20(1):157-64. doi: 10.1007/s00330-009-1527-y. Epub 2009 Aug 13.


Dopamine release during human emotional processing.

Badgaiyan RD, Fischman AJ, Alpert NM.

Neuroimage. 2009 Oct 1;47(4):2041-5. doi: 10.1016/j.neuroimage.2009.06.008. Epub 2009 Jun 11.


Efficacy, safety, and biomarkers of neoadjuvant bevacizumab, radiation therapy, and fluorouracil in rectal cancer: a multidisciplinary phase II study.

Willett CG, Duda DG, di Tomaso E, Boucher Y, Ancukiewicz M, Sahani DV, Lahdenranta J, Chung DC, Fischman AJ, Lauwers GY, Shellito P, Czito BG, Wong TZ, Paulson E, Poleski M, Vujaskovic Z, Bentley R, Chen HX, Clark JW, Jain RK.

J Clin Oncol. 2009 Jun 20;27(18):3020-6. doi: 10.1200/JCO.2008.21.1771. Epub 2009 May 26.


Pancreatic imaging with 11C-dihydrotetrabenazine PET: a perspective.

Fagan SP, Fischman AJ.

J Nucl Med. 2009 Mar;50(3):335-7. doi: 10.2967/jnumed.108.059568. Epub 2009 Feb 17. No abstract available.

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