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Items: 1 to 50 of 242

1.

Draft Reference Genome Sequence of Corynebacterium mastitidis 16-1433, Isolated from a Mouse.

Cheleuitte-Nieves C, Gulvik CA, Humrighouse BW, Bell ME, Villarma A, Westblade LF, Lipman NS, Fischetti VA, McQuiston JR.

Genome Announc. 2018 Feb 15;6(7). pii: e00050-18. doi: 10.1128/genomeA.00050-18.

2.

A novel plasmid, pSAA0430-08, from Streptococcus anginosus subsp. anginosus strain 0430-08.

Tabata A, Deutsch D, Otsuka S, Verratti K, Tomoyasu T, Nagamune H, Fischetti VA.

Plasmid. 2018 Jan;95:16-27. doi: 10.1016/j.plasmid.2018.01.002.

PMID:
29355570
3.

Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome.

Sela U, Euler CW, Correa da Rosa J, Fischetti VA.

PLoS Pathog. 2018 Jan 11;14(1):e1006726. doi: 10.1371/journal.ppat.1006726. eCollection 2018 Jan.

4.

Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis.

Raz A, Serrano A, Lawson C, Thaker M, Alston T, Bournazos S, Ravetch JV, Fischetti VA.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4781-4786. doi: 10.1073/pnas.1619249114. Epub 2017 Apr 20.

5.

Propionibacterium acnes biofilm is present in intervertebral discs of patients undergoing microdiscectomy.

Capoor MN, Ruzicka F, Schmitz JE, James GA, Machackova T, Jancalek R, Smrcka M, Lipina R, Ahmed FS, Alamin TF, Anand N, Baird JC, Bhatia N, Demir-Deviren S, Eastlack RK, Fisher S, Garfin SR, Gogia JS, Gokaslan ZL, Kuo CC, Lee YP, Mavrommatis K, Michu E, Noskova H, Raz A, Sana J, Shamie AN, Stewart PS, Stonemetz JL, Wang JC, Witham TF, Coscia MF, Birkenmaier C, Fischetti VA, Slaby O.

PLoS One. 2017 Apr 3;12(4):e0174518. doi: 10.1371/journal.pone.0174518. eCollection 2017.

7.

Oral Multiple Sclerosis Drugs Inhibit the In vitro Growth of Epsilon Toxin Producing Gut Bacterium, Clostridium perfringens.

Rumah KR, Vartanian TK, Fischetti VA.

Front Cell Infect Microbiol. 2017 Jan 25;7:11. doi: 10.3389/fcimb.2017.00011. eCollection 2017.

8.

The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa.

Gilmer DB, Schmitz JE, Thandar M, Euler CW, Fischetti VA.

PLoS One. 2017 Jan 3;12(1):e0169180. doi: 10.1371/journal.pone.0169180. eCollection 2017.

9.

Chronic lymphocytic leukemia immunoglobulins display bacterial reactivity that converges and diverges from auto-/poly-reactivity and IGHV mutation status.

Hatzi K, Catera R, Moreno Atanasio C, Fischetti VA, Allen SL, Kolitz JE, Rai KR, Chu CC, Chiorazzi N.

Clin Immunol. 2016 Nov;172:44-51. doi: 10.1016/j.clim.2016.08.020. Epub 2016 Aug 29.

PMID:
27586592
10.

Uncovering novel mobile genetic elements and their dynamics through an extra-chromosomal sequencing approach.

Deutsch DR, Utter B, Fischetti VA.

Mob Genet Elements. 2016 May 17;6(4):e1189987. doi: 10.1080/2159256X.2016.1189987. eCollection 2016 Jul-Aug.

11.

Prevalence of Propionibacterium acnes in Intervertebral Discs of Patients Undergoing Lumbar Microdiscectomy: A Prospective Cross-Sectional Study.

Capoor MN, Ruzicka F, Machackova T, Jancalek R, Smrcka M, Schmitz JE, Hermanova M, Sana J, Michu E, Baird JC, Ahmed FS, Maca K, Lipina R, Alamin TF, Coscia MF, Stonemetz JL, Witham T, Ehrlich GD, Gokaslan ZL, Mavrommatis K, Birkenmaier C, Fischetti VA, Slaby O.

PLoS One. 2016 Aug 18;11(8):e0161676. doi: 10.1371/journal.pone.0161676. eCollection 2016.

12.

One More Disguise in the Stealth Behavior of Streptococcus pyogenes.

Fischetti VA, Dale JB.

MBio. 2016 May 17;7(3). pii: e00661-16. doi: 10.1128/mBio.00661-16.

13.

A bacteriophage endolysin that eliminates intracellular streptococci.

Shen Y, Barros M, Vennemann T, Gallagher DT, Yin Y, Linden SB, Heselpoth RD, Spencer DJ, Donovan DM, Moult J, Fischetti VA, Heinrich F, Lösche M, Nelson DC.

Elife. 2016 Mar 15;5. pii: e13152. doi: 10.7554/eLife.13152.

14.

M Protein and Other Surface Proteins on Streptococci.

Fischetti VA.

In: Ferretti JJ, Stevens DL, Fischetti VA, editors. Streptococcus pyogenes : Basic Biology to Clinical Manifestations [Internet]. Oklahoma City (OK): University of Oklahoma Health Sciences Center; 2016-.
2016 Feb 10.

15.

Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.

Thandar M, Lood R, Winer BY, Deutsch DR, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2671-9. doi: 10.1128/AAC.02972-15. Print 2016 May.

16.

Alternatives to antibiotics-a pipeline portfolio review.

Czaplewski L, Bax R, Clokie M, Dawson M, Fairhead H, Fischetti VA, Foster S, Gilmore BF, Hancock RE, Harper D, Henderson IR, Hilpert K, Jones BV, Kadioglu A, Knowles D, Ólafsdóttir S, Payne D, Projan S, Shaunak S, Silverman J, Thomas CM, Trust TJ, Warn P, Rex JH.

Lancet Infect Dis. 2016 Feb;16(2):239-51. doi: 10.1016/S1473-3099(15)00466-1. Epub 2016 Jan 13. Review.

PMID:
26795692
17.

Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique.

Euler CW, Juncosa B, Ryan PA, Deutsch DR, McShan WM, Fischetti VA.

PLoS One. 2016 Jan 12;11(1):e0146408. doi: 10.1371/journal.pone.0146408. eCollection 2016.

18.

Dendritic Cells Induce a Subpopulation of IL-12Rβ2-Expressing Treg that Specifically Consumes IL-12 to Control Th1 Responses.

Sela U, Park CG, Park A, Olds P, Wang S, Steinman RM, Fischetti VA.

PLoS One. 2016 Jan 8;11(1):e0146412. doi: 10.1371/journal.pone.0146412. eCollection 2016.

19.

Lysin Therapy for Staphylococcus aureus and Other Bacterial Pathogens.

Fischetti VA.

Curr Top Microbiol Immunol. 2017;409:529-540. doi: 10.1007/82_2015_5005.

PMID:
26728063
20.

Elimination of Chromosomal Island SpyCIM1 from Streptococcus pyogenes Strain SF370 Reverses the Mutator Phenotype and Alters Global Transcription.

Hendrickson C, Euler CW, Nguyen SV, Rahman M, McCullor KA, King CJ, Fischetti VA, McShan WM.

PLoS One. 2015 Dec 23;10(12):e0145884. doi: 10.1371/journal.pone.0145884. eCollection 2015.

21.

Streptococcus pyogenes Sortase Mutants Are Highly Susceptible to Killing by Host Factors Due to Aberrant Envelope Physiology.

Raz A, Tanasescu AM, Zhao AM, Serrano A, Alston T, Sol A, Bachrach G, Fischetti VA.

PLoS One. 2015 Oct 20;10(10):e0140784. doi: 10.1371/journal.pone.0140784. eCollection 2015.

22.

Using a Novel Lysin To Help Control Clostridium difficile Infections.

Wang Q, Euler CW, Delaune A, Fischetti VA.

Antimicrob Agents Chemother. 2015 Dec;59(12):7447-57. doi: 10.1128/AAC.01357-15. Epub 2015 Sep 21.

23.

Prothrombin Time and Activated Partial Thromboplastin Time Testing: A Comparative Effectiveness Study in a Million-Patient Sample.

Capoor MN, Stonemetz JL, Baird JC, Ahmed FS, Awan A, Birkenmaier C, Inchiosa MA Jr, Magid SK, McGoldrick K, Molmenti E, Naqvi S, Parker SD, Pothula SM, Shander A, Steen RG, Urban MK, Wall J, Fischetti VA.

PLoS One. 2015 Aug 11;10(8):e0133317. doi: 10.1371/journal.pone.0133317. eCollection 2015.

24.

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin.

Rumah KR, Ma Y, Linden JR, Oo ML, Anrather J, Schaeren-Wiemers N, Alonso MA, Fischetti VA, McClain MS, Vartanian T.

PLoS Pathog. 2015 May 20;11(5):e1004896. doi: 10.1371/journal.ppat.1004896. eCollection 2015 May.

25.

A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae.

Díez-Martínez R, De Paz HD, García-Fernández E, Bustamante N, Euler CW, Fischetti VA, Menendez M, García P.

J Antimicrob Chemother. 2015;70(6):1763-73. doi: 10.1093/jac/dkv038. Epub 2015 Mar 1.

PMID:
25733585
26.

Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model.

Lood R, Winer BY, Pelzek AJ, Diez-Martinez R, Thandar M, Euler CW, Schuch R, Fischetti VA.

Antimicrob Agents Chemother. 2015 Apr;59(4):1983-91. doi: 10.1128/AAC.04641-14. Epub 2015 Jan 20.

27.

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.

Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA.

Nat Biotechnol. 2014 Nov;32(11):1146-50. doi: 10.1038/nbt.3043. Epub 2014 Oct 5.

28.

Beyond the chromosome: the prevalence of unique extra-chromosomal bacteriophages with integrated virulence genes in pathogenic Staphylococcus aureus.

Utter B, Deutsch DR, Schuch R, Winer BY, Verratti K, Bishop-Lilly K, Sozhamannan S, Fischetti VA.

PLoS One. 2014 Jun 25;9(6):e100502. doi: 10.1371/journal.pone.0100502. eCollection 2014.

29.

Complete Genome Sequence of Bacillus cereus Sensu Lato Bacteriophage Bcp1.

Schuch R, Pelzek AJ, Fazzini MM, Nelson DC, Fischetti VA.

Genome Announc. 2014 Jun 12;2(3). pii: e00334-14. doi: 10.1128/genomeA.00334-14.

30.

A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia.

Lood R, Raz A, Molina H, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2014 Jun;58(6):3073-84. doi: 10.1128/AAC.00115-14. Epub 2014 Mar 17.

31.

Discovery of Novel Putative Inhibitors of UDP-GlcNAc 2-Epimerase as Potent Antibacterial Agents.

Xu Y, Brenning B, Clifford A, Vollmer D, Bearss J, Jones C, McCarthy V, Shi C, Wolfe B, Aavula B, Warner S, Bearss DJ, McCullar MV, Schuch R, Pelzek A, Bhaskaran SS, Stebbins CE, Goldberg AR, Fischetti VA, Vankayalapati H.

ACS Med Chem Lett. 2013 Dec 12;4(12):1142-1147.

32.

Combination therapy with lysin CF-301 and antibiotic is superior to antibiotic alone for treating methicillin-resistant Staphylococcus aureus-induced murine bacteremia.

Schuch R, Lee HM, Schneider BC, Sauve KL, Law C, Khan BK, Rotolo JA, Horiuchi Y, Couto DE, Raz A, Fischetti VA, Huang DB, Nowinski RC, Wittekind M.

J Infect Dis. 2014 May 1;209(9):1469-78. doi: 10.1093/infdis/jit637. Epub 2013 Nov 28.

33.

Isolation of Clostridium perfringens type B in an individual at first clinical presentation of multiple sclerosis provides clues for environmental triggers of the disease.

Rumah KR, Linden J, Fischetti VA, Vartanian T.

PLoS One. 2013 Oct 16;8(10):e76359. doi: 10.1371/journal.pone.0076359. eCollection 2013.

34.

Bactericidal synergism between daptomycin and the phage lysin Cpl-1 in a mouse model of pneumococcal bacteraemia.

Vouillamoz J, Entenza JM, Giddey M, Fischetti VA, Moreillon P, Resch G.

Int J Antimicrob Agents. 2013 Nov;42(5):416-21. doi: 10.1016/j.ijantimicag.2013.06.020. Epub 2013 Aug 9.

PMID:
23992647
35.

Identification of a ligand on the Wip1 bacteriophage highly specific for a receptor on Bacillus anthracis.

Kan S, Fornelos N, Schuch R, Fischetti VA.

J Bacteriol. 2013 Oct;195(19):4355-64. doi: 10.1128/JB.00655-13. Epub 2013 Jul 26.

36.

Lysins: the arrival of pathogen-directed anti-infectives.

Pastagia M, Schuch R, Fischetti VA, Huang DB.

J Med Microbiol. 2013 Oct;62(Pt 10):1506-16. doi: 10.1099/jmm.0.061028-0. Epub 2013 Jun 27. Review.

PMID:
23813275
37.

Attenuated neutrophil axis in atopic dermatitis compared to psoriasis reflects TH17 pathway differences between these diseases.

Dhingra N, Suárez-Fariñas M, Fuentes-Duculan J, Gittler JK, Shemer A, Raz A, Fischetti VA, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2013 Aug;132(2):498-501.e3. doi: 10.1016/j.jaci.2013.04.043. Epub 2013 Jun 15. No abstract available.

38.

Anthrax SET protein: a potential virulence determinant that epigenetically represses NF-κB activation in infected macrophages.

Mujtaba S, Winer BY, Jaganathan A, Patel J, Sgobba M, Schuch R, Gupta YK, Haider S, Wang R, Fischetti VA.

J Biol Chem. 2013 Aug 9;288(32):23458-72. doi: 10.1074/jbc.M113.467696. Epub 2013 May 29.

39.

Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia.

Doehn JM, Fischer K, Reppe K, Gutbier B, Tschernig T, Hocke AC, Fischetti VA, Löffler J, Suttorp N, Hippenstiel S, Witzenrath M.

J Antimicrob Chemother. 2013 Sep;68(9):2111-7. doi: 10.1093/jac/dkt131. Epub 2013 Apr 30.

PMID:
23633685
40.

Group A streptococcal vaccines: paving a path for accelerated development.

Dale JB, Fischetti VA, Carapetis JR, Steer AC, Sow S, Kumar R, Mayosi BM, Rubin FA, Mulholland K, Hombach JM, Schödel F, Henao-Restrepo AM.

Vaccine. 2013 Apr 18;31 Suppl 2:B216-22. doi: 10.1016/j.vaccine.2012.09.045. Review.

PMID:
23598485
41.

Use of a bacteriophage lysin to identify a novel target for antimicrobial development.

Schuch R, Pelzek AJ, Raz A, Euler CW, Ryan PA, Winer BY, Farnsworth A, Bhaskaran SS, Stebbins CE, Xu Y, Clifford A, Bearss DJ, Vankayalapati H, Goldberg AR, Fischetti VA.

PLoS One. 2013 Apr 10;8(4):e60754. doi: 10.1371/journal.pone.0060754. Print 2013.

42.

Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus.

Gilmer DB, Schmitz JE, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2013 Jun;57(6):2743-50. doi: 10.1128/AAC.02526-12. Epub 2013 Apr 9.

43.

Structural investigations of a Podoviridae streptococcus phage C1, implications for the mechanism of viral entry.

Aksyuk AA, Bowman VD, Kaufmann B, Fields C, Klose T, Holdaway HA, Fischetti VA, Rossmann MG.

Proc Natl Acad Sci U S A. 2012 Aug 28;109(35):14001-6. doi: 10.1073/pnas.1207730109. Epub 2012 Aug 13.

44.

X-ray crystal structure of the streptococcal specific phage lysin PlyC.

McGowan S, Buckle AM, Mitchell MS, Hoopes JT, Gallagher DT, Heselpoth RD, Shen Y, Reboul CF, Law RH, Fischetti VA, Whisstock JC, Nelson DC.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12752-7. doi: 10.1073/pnas.1208424109. Epub 2012 Jul 17.

45.

Cellular aspects of the distinct M protein and SfbI anchoring pathways in Streptococcus pyogenes.

Raz A, Talay SR, Fischetti VA.

Mol Microbiol. 2012 May;84(4):631-47. doi: 10.1111/j.1365-2958.2012.08047.x. Epub 2012 Apr 19.

46.

Characterization of recombinant Streptococcus mitis-derived human platelet aggregation factor.

Ohkuni H, Nagamune H, Ozaki N, Tabata A, Todome Y, Watanabe Y, Takahashi H, Ohkura K, Kourai H, Ohtsuka H, Fischetti VA, Zabriskie JB.

APMIS. 2012 Jan;120(1):56-71. doi: 10.1111/j.1600-0463.2011.02813.x. Epub 2011 Sep 27.

PMID:
22151309
47.

PEGylating a bacteriophage endolysin inhibits its bactericidal activity.

Resch G, Moreillon P, Fischetti VA.

AMB Express. 2011 Oct 7;1:29. doi: 10.1186/2191-0855-1-29.

48.

A stable phage lysin (Cpl-1) dimer with increased antipneumococcal activity and decreased plasma clearance.

Resch G, Moreillon P, Fischetti VA.

Int J Antimicrob Agents. 2011 Dec;38(6):516-21. doi: 10.1016/j.ijantimicag.2011.08.009. Epub 2011 Oct 5.

PMID:
21982146
49.

Exploiting what phage have evolved to control gram-positive pathogens.

Fischetti VA.

Bacteriophage. 2011 Jul 1;1(4):188-194.

50.

A novel chimeric lysin shows superiority to mupirocin for skin decolonization of methicillin-resistant and -sensitive Staphylococcus aureus strains.

Pastagia M, Euler C, Chahales P, Fuentes-Duculan J, Krueger JG, Fischetti VA.

Antimicrob Agents Chemother. 2011 Feb;55(2):738-44. doi: 10.1128/AAC.00890-10. Epub 2010 Nov 22.

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