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Items: 1 to 50 of 51

1.

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS.

Ouali Alami N, Schurr C, Olde Heuvel F, Tang L, Li Q, Tasdogan A, Kimbara A, Nettekoven M, Ottaviani G, Raposo C, Röver S, Rogers-Evans M, Rothenhäusler B, Ullmer C, Fingerle J, Grether U, Knuesel I, Boeckers TM, Ludolph A, Wirth T, Roselli F, Baumann B.

EMBO J. 2018 Jun 6. pii: e98697. doi: 10.15252/embj.201798697. [Epub ahead of print]

2.

Regulated efflux of photoreceptor outer segment-derived cholesterol by human RPE cells.

Storti F, Raphael G, Griesser V, Klee K, Drawnel F, Willburger C, Scholz R, Langmann T, von Eckardstein A, Fingerle J, Grimm C, Maugeais C.

Exp Eye Res. 2017 Dec;165:65-77. doi: 10.1016/j.exer.2017.09.008. Epub 2017 Sep 21.

PMID:
28943268
3.

A Novel Selective Inverse Agonist of the CB2 Receptor as a Radiolabeled Tool Compound for Kinetic Binding Studies.

Martella A, Sijben H, Rufer AC, Grether U, Fingerle J, Ullmer C, Hartung T, IJzerman AP, van der Stelt M, Heitman LH.

Mol Pharmacol. 2017 Oct;92(4):389-400. doi: 10.1124/mol.117.108605. Epub 2017 Jul 26.

PMID:
28747489
4.

Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.

Soethoudt M, Grether U, Fingerle J, Grim TW, Fezza F, de Petrocellis L, Ullmer C, Rothenhäusler B, Perret C, van Gils N, Finlay D, MacDonald C, Chicca A, Gens MD, Stuart J, de Vries H, Mastrangelo N, Xia L, Alachouzos G, Baggelaar MP, Martella A, Mock ED, Deng H, Heitman LH, Connor M, Di Marzo V, Gertsch J, Lichtman AH, Maccarrone M, Pacher P, Glass M, van der Stelt M.

Nat Commun. 2017 Jan 3;8:13958. doi: 10.1038/ncomms13958.

5.

Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy.

Zoja C, Locatelli M, Corna D, Villa S, Rottoli D, Nava V, Verde R, Piscitelli F, Di Marzo V, Fingerle J, Adam JM, Rothenhaeusler B, Ottaviani G, Bénardeau A, Abbate M, Remuzzi G, Benigni A.

Nephron. 2016;132(1):59-69. doi: 10.1159/000442679. Epub 2015 Dec 9.

PMID:
26646377
6.

2-Methoxyestradiol blocks the RhoA/ROCK1 pathway in human aortic smooth muscle cells.

Rigassi L, Barchiesi Bozzolo F, Lucchinetti E, Zaugg M, Fingerle J, Rosselli M, Imthurn B, Jackson EK, Dubey RK.

Am J Physiol Endocrinol Metab. 2015 Dec 15;309(12):E995-1007. doi: 10.1152/ajpendo.00267.2015. Epub 2015 Oct 20.

7.

Adenosine Attenuates Human Coronary Artery Smooth Muscle Cell Proliferation by Inhibiting Multiple Signaling Pathways That Converge on Cyclin D.

Dubey RK, Fingerle J, Gillespie DG, Mi Z, Rosselli M, Imthurn B, Jackson EK.

Hypertension. 2015 Dec;66(6):1207-19. doi: 10.1161/HYPERTENSIONAHA.115.05912. Epub 2015 Sep 28.

8.

Novel Triazolopyrimidine-Derived Cannabinoid Receptor 2 Agonists as Potential Treatment for Inflammatory Kidney Diseases.

Nettekoven M, Adam JM, Bendels S, Bissantz C, Fingerle J, Grether U, Grüner S, Guba W, Kimbara A, Ottaviani G, Püllmann B, Rogers-Evans M, Röver S, Rothenhäusler B, Schmitt S, Schuler F, Schulz-Gasch T, Ullmer C.

ChemMedChem. 2016 Jan 19;11(2):179-89. doi: 10.1002/cmdc.201500218. Epub 2015 Jul 21.

PMID:
26228928
9.

Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor.

Slavik R, Grether U, Müller Herde A, Gobbi L, Fingerle J, Ullmer C, Krämer SD, Schibli R, Mu L, Ametamey SM.

J Med Chem. 2015 May 28;58(10):4266-77. doi: 10.1021/acs.jmedchem.5b00283. Epub 2015 May 14.

PMID:
25950914
10.

Selective cathepsin S inhibition attenuates atherosclerosis in apolipoprotein E-deficient mice with chronic renal disease.

Figueiredo JL, Aikawa M, Zheng C, Aaron J, Lax L, Libby P, de Lima Filho JL, Gruener S, Fingerle J, Haap W, Hartmann G, Aikawa E.

Am J Pathol. 2015 Apr;185(4):1156-66. doi: 10.1016/j.ajpath.2014.11.026. Epub 2015 Feb 10.

11.

Highly potent and selective cannabinoid receptor 2 agonists: initial hit optimization of an adamantyl hit series identified from high-through-put screening.

Nettekoven M, Fingerle J, Grether U, Grüner S, Kimbara A, Püllmann B, Rogers-Evans M, Röver S, Schuler F, Schulz-Gasch T, Ullmer C.

Bioorg Med Chem Lett. 2013 Mar 1;23(5):1177-81. doi: 10.1016/j.bmcl.2013.01.044. Epub 2013 Jan 23.

PMID:
23380378
12.

Trimerized apolipoprotein A-I (TripA) forms lipoproteins, activates lecithin: cholesterol acyltransferase, elicits lipid efflux, and is transported through aortic endothelial cells.

Ohnsorg PM, Mary JL, Rohrer L, Pech M, Fingerle J, von Eckardstein A.

Biochim Biophys Acta. 2011 Dec;1811(12):1115-23. doi: 10.1016/j.bbalip.2011.09.001. Epub 2011 Sep 10.

PMID:
21930241
13.

Mast cell chymase inhibition reduces atherosclerotic plaque progression and improves plaque stability in ApoE-/- mice.

Bot I, Bot M, van Heiningen SH, van Santbrink PJ, Lankhuizen IM, Hartman P, Gruener S, Hilpert H, van Berkel TJ, Fingerle J, Biessen EA.

Cardiovasc Res. 2011 Jan 1;89(1):244-52. doi: 10.1093/cvr/cvq260. Epub 2010 Aug 6.

PMID:
20693162
14.

Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases.

Caughey GH, Beauchamp J, Schlatter D, Raymond WW, Trivedi NN, Banner D, Mauser H, Fingerle J.

J Biol Chem. 2008 May 16;283(20):13943-51. doi: 10.1074/jbc.M710502200. Epub 2008 Mar 19.

15.

2-Methoxyestradiol, an estradiol metabolite, inhibits neointima formation and smooth muscle cell growth via double blockade of the cell cycle.

Barchiesi F, Jackson EK, Fingerle J, Gillespie DG, Odermatt B, Dubey RK.

Circ Res. 2006 Aug 4;99(3):266-74. Epub 2006 Jun 22.

16.
17.

New experimental setup for studying strictly noninvasively skeletal muscle function in rat using 1H-magnetic resonance (MR) imaging and 31P-MR spectroscopy.

Giannesini B, Izquierdo M, Le Fur Y, Cozzone PJ, Fingerle J, Himber J, Künnecke B, Von Kienlin M, Bendahan D.

Magn Reson Med. 2005 Nov;54(5):1058-64.

18.

Differential regulation of estrogen receptor subtypes alpha and beta in human aortic smooth muscle cells by oligonucleotides and estradiol.

Barchiesi F, Jackson EK, Imthurn B, Fingerle J, Gillespie DG, Dubey RK.

J Clin Endocrinol Metab. 2004 May;89(5):2373-81.

PMID:
15126566
19.

The gene encoding phosphodiesterase 4D confers risk of ischemic stroke.

Gretarsdottir S, Thorleifsson G, Reynisdottir ST, Manolescu A, Jonsdottir S, Jonsdottir T, Gudmundsdottir T, Bjarnadottir SM, Einarsson OB, Gudjonsdottir HM, Hawkins M, Gudmundsson G, Gudmundsdottir H, Andrason H, Gudmundsdottir AS, Sigurdardottir M, Chou TT, Nahmias J, Goss S, Sveinbjörnsdottir S, Valdimarsson EM, Jakobsson F, Agnarsson U, Gudnason V, Thorgeirsson G, Fingerle J, Gurney M, Gudbjartsson D, Frigge ML, Kong A, Stefansson K, Gulcher JR.

Nat Genet. 2003 Oct;35(2):131-8. Epub 2003 Sep 21. Erratum in: Nat Genet. 2005 May;37(5):555.

20.
21.

Inhibition of NO biosynthesis, but not elevated blood pressure, reduces angiogenesis in rat models of secondary hypertension.

Kiefer FN, Misteli H, Kalak N, Tschudin K, Fingerle J, Van der Kooij M, Stumm M, Sumanovski LT, Sieber CC, Battegay EJ.

Blood Press. 2002;11(2):116-24.

PMID:
12035872
22.

Methoxyestradiols mediate estradiol-induced antimitogenesis in human aortic SMCs.

Barchiesi F, Jackson EK, Gillespie DG, Zacharia LC, Fingerle J, Dubey RK.

Hypertension. 2002 Apr;39(4):874-9.

23.

Metalloproteinase inhibition and the response to angioplasty and stenting in atherosclerotic primates.

Cherr GS, Motew SJ, Travis JA, Fingerle J, Fisher L, Brandl M, Williams JK, Geary RL.

Arterioscler Thromb Vasc Biol. 2002 Jan;22(1):161-6.

24.

Methoxyestradiols mediate the antimitogenic effects of estradiol on vascular smooth muscle cells via estrogen receptor-independent mechanisms.

Dubey RK, Gillespie DG, Zacharia LC, Rosselli M, Korzekwa KR, Fingerle J, Jackson EK.

Biochem Biophys Res Commun. 2000 Nov 11;278(1):27-33.

PMID:
11071850
25.

Cholera toxin treatment of vascular smooth muscle cells decreases smooth muscle alpha-actin content and abolishes the platelet-derived growth factor-BB-stimulated DNA synthesis.

Sachinidis A, Seul C, Gouni-Berthold I, Seewald S, Ko Y, Vetter H, Fingerle J, Hoppe J.

Br J Pharmacol. 2000 Aug;130(7):1561-70.

26.

Angiotensin II-induced progression of neointimal thickening in the balloon-injured rat carotid artery is AT1 receptor mediated.

van Kleef EM, Fingerle J, Daemen MJ.

Arterioscler Thromb Vasc Biol. 1996 Jul;16(7):857-63.

27.

Ca2+ entry and vasoconstriction during osmotic swelling of vascular smooth muscle cells.

Lang F, Busch GL, Zempel G, Ditlevsen J, Hoch M, Emerich U, Axel D, Fingerle J, Meierkord S, Apfel H, et al.

Pflugers Arch. 1995 Dec;431(2):253-8.

PMID:
9026786
29.
30.

Effects of H2O2 on membrane potential and [Ca2+]i of cultured rat arterial smooth muscle cells.

Krippeit-Drews P, Haberland C, Fingerle J, Drews G, Lang F.

Biochem Biophys Res Commun. 1995 Apr 6;209(1):139-45.

PMID:
7537038
31.

Renal proliferative and phenotypic changes in rats with two-kidney, one-clip Goldblatt hypertension.

Eng E, Veniant M, Floege J, Fingerle J, Alpers CE, Menard J, Clozel JP, Johnson RJ.

Am J Hypertens. 1994 Feb;7(2):177-85.

PMID:
8179853
32.

Mouse model of arterial injury.

Lindner V, Fingerle J, Reidy MA.

Circ Res. 1993 Nov;73(5):792-6.

33.

[Comparative study of vascular prostheses of polytetrafluorethylene and polyurethane].

Jeschke M, Hermanutz V, Frick E, Fingerle J, Köveker G.

Helv Chir Acta. 1993 Jun;59(5-6):881-6. German. No abstract available.

PMID:
8376158
34.

Pituitary factors in blood plasma are necessary for smooth muscle cell proliferation in response to injury in vivo.

Fingerle J, Faulmüller A, Müller G, Bowen-Pope DF, Clowes MM, Reidy MA, Clowes AW.

Arterioscler Thromb. 1992 Dec;12(12):1488-95.

35.

Factors controlling the development of arterial lesions after injury.

Reidy MA, Fingerle J, Lindner V.

Circulation. 1992 Dec;86(6 Suppl):III43-6. Review.

PMID:
1424050
37.

[Experimental study of small caliber vascular prostheses--importance of the endothelium for intima hyperplasia].

Hermanutz V, Köveker GB, Fingerle J.

Vasa Suppl. 1992;35:158-9. German. No abstract available.

PMID:
1481027
38.

[Model of extracorporeal perfusion of vascular prosthesis in controlled pressure and flow conditions].

Brugger H, Köveker GB, Fingerle J.

Vasa Suppl. 1992;35:153-4. German. No abstract available.

PMID:
1481025
39.

T lymphocytes inhibit the vascular response to injury.

Hansson GK, Holm J, Holm S, Fotev Z, Hedrich HJ, Fingerle J.

Proc Natl Acad Sci U S A. 1991 Dec 1;88(23):10530-4.

40.
41.

Intimal lesion formation in rat carotid arteries after endothelial denudation in absence of medial injury.

Fingerle J, Au YP, Clowes AW, Reidy MA.

Arteriosclerosis. 1990 Nov-Dec;10(6):1082-7.

42.

Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.

Fingerle J, Johnson R, Clowes AW, Majesky MW, Reidy MA.

Proc Natl Acad Sci U S A. 1989 Nov;86(21):8412-6.

43.
44.
45.

Structural alterations in vascular endothelial tight junctions in the course of their gradual degradation in vitro.

Mühleisen H, Fingerle J, Wolburg H, Betz E.

Tissue Cell. 1989;21(6):803-11.

PMID:
2629163
46.

Intimal thickenings of jugular veins after application of a stimulus known to be sclerogenic in arteries.

Kling D, Lindner V, Fingerle J, Betz E.

Virchows Arch A Pathol Anat Histopathol. 1989;415(4):367-75.

PMID:
2505448
47.

Regulation of smooth muscle cell growth in injured artery.

Clowes AW, Clowes MM, Fingerle J, Reidy MA.

J Cardiovasc Pharmacol. 1989;14 Suppl 6:S12-15. Review.

PMID:
2478818
48.

Expression of smooth muscle myosin in relation to growth kinetics of cultured aortic smooth muscle cells.

Hämmerle H, Fingerle J, Rupp J, Grünwald J, Betz E, Haudenschild CC.

Exp Cell Res. 1988 Oct;178(2):390-400.

PMID:
2971558
49.

Cytocontractile structures and proteins of smooth muscle cells during the formation of experimental lesions.

Grünwald J, Fingerle J, Hämmerle H, Betz E, Haudenschild CC.

Exp Mol Pathol. 1987 Feb;46(1):78-88.

PMID:
2948834
50.

The induction of smooth muscle cell proliferation in vitro using an organ culture system.

Fingerle J, Kraft T.

Int Angiol. 1987 Jan-Mar;6(1):65-72.

PMID:
3624950

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