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Items: 1 to 50 of 180

1.

Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Mar;3(3):387. doi: 10.1038/s41564-017-0100-8.

PMID:
29440749
2.

Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells.

Watkins TN, Liu H, Chung M, Hazen TH, Dunning Hotopp JC, Filler SG, Bruno VM.

Microb Genom. 2018 Jan 18. doi: 10.1099/mgen.0.000154. [Epub ahead of print]

3.

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.

McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S.

Nat Chem Biol. 2018 Feb;14(2):135-141. doi: 10.1038/nchembio.2534. Epub 2017 Dec 11.

PMID:
29227471
4.

EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Jan;3(1):53-61. doi: 10.1038/s41564-017-0059-5. Epub 2017 Nov 13. Erratum in: Nat Microbiol. 2018 Feb 13;:.

PMID:
29133884
5.

Yeast casein kinase 2 governs morphology, biofilm formation, cell wall integrity, and host cell damage of Candida albicans.

Jung SI, Rodriguez N, Irrizary J, Liboro K, Bogarin T, Macias M, Eivers E, Porter E, Filler SG, Park H.

PLoS One. 2017 Nov 6;12(11):e0187721. doi: 10.1371/journal.pone.0187721. eCollection 2017.

6.

Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00390-17. doi: 10.1128/AAC.00390-17. Print 2017 Sep.

PMID:
28652241
7.

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.

Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. doi: 10.1073/pnas.1702798114. Epub 2017 Jun 20.

8.

The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis.

Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG.

MBio. 2017 Mar 21;8(2). pii: e00025-17. doi: 10.1128/mBio.00025-17.

9.

Role of Arf GTPases in fungal morphogenesis and virulence.

Labbaoui H, Bogliolo S, Ghugtyal V, Solis NV, Filler SG, Arkowitz RA, Bassilana M.

PLoS Pathog. 2017 Feb 13;13(2):e1006205. doi: 10.1371/journal.ppat.1006205. eCollection 2017 Feb.

10.

The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.

Kwon-Chung KJ, Bennett JE, Wickes BL, Meyer W, Cuomo CA, Wollenburg KR, Bicanic TA, Castañeda E, Chang YC, Chen J, Cogliati M, Dromer F, Ellis D, Filler SG, Fisher MC, Harrison TS, Holland SM, Kohno S, Kronstad JW, Lazera M, Levitz SM, Lionakis MS, May RC, Ngamskulrongroj P, Pappas PG, Perfect JR, Rickerts V, Sorrell TC, Walsh TJ, Williamson PR, Xu J, Zelazny AM, Casadevall A.

mSphere. 2017 Jan 11;2(1). pii: e00357-16. doi: 10.1128/mSphere.00357-16. eCollection 2017 Jan-Feb.

11.

Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses.

Swidergall M, Filler SG.

PLoS Pathog. 2017 Jan 12;13(1):e1006056. doi: 10.1371/journal.ppat.1006056. eCollection 2017 Jan. Review. No abstract available.

12.

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL.

Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27.

13.

Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus.

Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR.

Infect Immun. 2017 Jan 26;85(2). pii: e00876-16. doi: 10.1128/IAI.00876-16. Print 2017 Feb.

14.

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion.

Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG.

Nat Microbiol. 2016 Nov 14;2:16211. doi: 10.1038/nmicrobiol.2016.211.

15.

Cryptococcus gattii Meningitis Complicated by Listeria monocytogenes Infection.

Deiss RG, Bolaris M, Wang A, Filler SG.

Emerg Infect Dis. 2016 Sep;22(9):1669-71. doi: 10.3201/eid2209.160142. No abstract available.

16.

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi.

Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM.

Nat Commun. 2016 Jul 22;7:12218. doi: 10.1038/ncomms12218.

17.

Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis.

Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE Jr, Filler SG, Ibrahim AS.

J Clin Invest. 2016 Jun 1;126(6):2280-94. doi: 10.1172/JCI82744. Epub 2016 May 9.

18.

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation.

Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC.

MBio. 2016 Apr 5;7(2):e00252-16. doi: 10.1128/mBio.00252-16.

19.

Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

J Vis Exp. 2016 Jan 13;(107):e53460. doi: 10.3791/53460.

20.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC.

PLoS Pathog. 2015 Oct 22;11(10):e1005187. doi: 10.1371/journal.ppat.1005187. eCollection 2015 Oct.

21.

Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

Methods Mol Biol. 2016;1361:57-65. doi: 10.1007/978-1-4939-3079-1_3.

22.

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Gebremariam T, Wiederhold NP, Fothergill AW, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS.

Antimicrob Agents Chemother. 2015 Dec;59(12):7815-7. doi: 10.1128/AAC.01437-15. Epub 2015 Sep 14.

23.

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus.

Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE Jr, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP Jr, Yeaman MR.

Infect Immun. 2015 Nov;83(11):4427-37. doi: 10.1128/IAI.01061-15. Epub 2015 Sep 8.

24.

Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction.

Gil-Bona A, Parra-Giraldo CM, Hernáez ML, Reales-Calderon JA, Solis NV, Filler SG, Monteoliva L, Gil C.

J Proteomics. 2015 Sep 8;127(Pt B):340-351. doi: 10.1016/j.jprot.2015.06.006. Epub 2015 Jun 15.

25.

Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis.

Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM.

PLoS Pathog. 2015 Jun 18;11(6):e1004943. doi: 10.1371/journal.ppat.1004943. eCollection 2015 Jun. No abstract available.

26.

New signaling pathways govern the host response to C. albicans infection in various niches.

Liu Y, Shetty AC, Schwartz JA, Bradford LL, Xu W, Phan QT, Kumari P, Mahurkar A, Mitchell AP, Ravel J, Fraser CM, Filler SG, Bruno VM.

Genome Res. 2015 May;25(5):679-89. doi: 10.1101/gr.187427.114. Epub 2015 Apr 9.

27.

Activation and alliance of regulatory pathways in C. albicans during mammalian infection.

Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP.

PLoS Biol. 2015 Feb 18;13(2):e1002076. doi: 10.1371/journal.pbio.1002076. eCollection 2015 Feb.

28.

Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract.

Shankar J, Solis NV, Mounaud S, Szpakowski S, Liu H, Losada L, Nierman WC, Filler SG.

Sci Rep. 2015 Feb 3;5:8131. doi: 10.1038/srep08131.

29.

A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses.

Shankar J, Szpakowski S, Solis NV, Mounaud S, Liu H, Losada L, Nierman WC, Filler SG.

BMC Bioinformatics. 2015 Feb 1;16:31. doi: 10.1186/s12859-015-0467-6.

30.

CX3CR1 is dispensable for control of mucosal Candida albicans infections in mice and humans.

Break TJ, Jaeger M, Solis NV, Filler SG, Rodriguez CA, Lim JK, Lee CC, Sobel JD, Netea MG, Lionakis MS.

Infect Immun. 2015 Mar;83(3):958-65. doi: 10.1128/IAI.02604-14. Epub 2014 Dec 29.

31.

Divergent targets of Aspergillus fumigatus AcuK and AcuM transcription factors during growth in vitro versus invasive disease.

Pongpom M, Liu H, Xu W, Snarr BD, Sheppard DC, Mitchell AP, Filler SG.

Infect Immun. 2015 Mar;83(3):923-33. doi: 10.1128/IAI.02685-14. Epub 2014 Dec 22.

32.

Mechanisms of NDV-3 vaccine efficacy in MRSA skin versus invasive infection.

Yeaman MR, Filler SG, Chaili S, Barr K, Wang H, Kupferwasser D, Hennessey JP Jr, Fu Y, Schmidt CS, Edwards JE Jr, Xiong YQ, Ibrahim AS.

Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5555-63. doi: 10.1073/pnas.1415610111. Epub 2014 Dec 8.

33.

Host cell invasion by medically important fungi.

Sheppard DC, Filler SG.

Cold Spring Harb Perspect Med. 2014 Nov 3;5(1):a019687. doi: 10.1101/cshperspect.a019687. Review.

34.

Systemic Staphylococcus aureus infection mediated by Candida albicans hyphal invasion of mucosal tissue.

Schlecht LM, Peters BM, Krom BP, Freiberg JA, Hänsch GM, Filler SG, Jabra-Rizk MA, Shirtliff ME.

Microbiology. 2015 Jan;161(Pt 1):168-181. doi: 10.1099/mic.0.083485-0. Epub 2014 Oct 20.

35.

The pH-responsive PacC transcription factor of Aspergillus fumigatus governs epithelial entry and tissue invasion during pulmonary aspergillosis.

Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM.

PLoS Pathog. 2014 Oct 16;10(10):e1004413. doi: 10.1371/journal.ppat.1004413. eCollection 2014 Oct. Erratum in: PLoS Pathog. 2015 Apr;11(4):e1004802.

36.

Applying Convergent Immunity to Innovative Vaccines Targeting Staphylococcus aureus.

Yeaman MR, Filler SG, Schmidt CS, Ibrahim AS, Edwards JE Jr, Hennessey JP Jr.

Front Immunol. 2014 Sep 26;5:463. doi: 10.3389/fimmu.2014.00463. eCollection 2014. Review.

37.

Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal.

Springer DJ, Billmyre RB, Filler EE, Voelz K, Pursall R, Mieczkowski PA, Larsen RA, Dietrich FS, May RC, Filler SG, Heitman J.

PLoS Pathog. 2014 Aug 21;10(8):e1004285. doi: 10.1371/journal.ppat.1004285. eCollection 2014 Aug.

38.

Different tumor necrosis factor α antagonists have different effects on host susceptibility to disseminated and oropharyngeal candidiasis in mice.

Park H, Solis NV, Louie JS, Spellberg B, Rodriguez N, Filler SG.

Virulence. 2014 Jul 1;5(5):625-9. doi: 10.4161/viru.29699. Epub 2014 Jul 9.

39.

In vitro models of hematogenously disseminated candidiasis.

Filler SG.

Virulence. 2014 Feb 15;5(2):240-2. doi: 10.4161/viru.27453. Epub 2014 Jan 2. No abstract available.

40.

Role of retrograde trafficking in stress response, host cell interactions, and virulence of Candida albicans.

Liu Y, Solis NV, Heilmann CJ, Phan QT, Mitchell AP, Klis FM, Filler SG.

Eukaryot Cell. 2014 Feb;13(2):279-87. doi: 10.1128/EC.00295-13. Epub 2013 Dec 20.

41.

CotH3 mediates fungal invasion of host cells during mucormycosis.

Gebremariam T, Liu M, Luo G, Bruno V, Phan QT, Waring AJ, Edwards JE Jr, Filler SG, Yeaman MR, Ibrahim AS.

J Clin Invest. 2014 Jan;124(1):237-50. doi: 10.1172/JCI71349. Epub 2013 Dec 20.

42.

Role of endothelial cell septin 7 in the endocytosis of Candida albicans.

Phan QT, Eng DK, Mostowy S, Park H, Cossart P, Filler SG.

MBio. 2013 Dec 17;4(6):e00542-13. doi: 10.1128/mBio.00542-13.

43.

Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides.

Lee MJ, Gravelat FN, Cerone RP, Baptista SD, Campoli PV, Choe SI, Kravtsov I, Vinogradov E, Creuzenet C, Liu H, Berghuis AM, Latgé JP, Filler SG, Fontaine T, Sheppard DC.

J Biol Chem. 2014 Jan 17;289(3):1243-56. doi: 10.1074/jbc.M113.522516. Epub 2013 Nov 20.

44.

Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans.

Lu Y, Su C, Solis NV, Filler SG, Liu H.

Cell Host Microbe. 2013 Nov 13;14(5):499-509. doi: 10.1016/j.chom.2013.10.008.

45.

Glycerophosphocholine utilization by Candida albicans: role of the Git3 transporter in virulence.

Bishop AC, Ganguly S, Solis NV, Cooley BM, Jensen-Seaman MI, Filler SG, Mitchell AP, Patton-Vogt J.

J Biol Chem. 2013 Nov 22;288(47):33939-52. doi: 10.1074/jbc.M113.505735. Epub 2013 Oct 10.

46.

NDV-3 protects mice from vulvovaginal candidiasis through T- and B-cell immune response.

Ibrahim AS, Luo G, Gebremariam T, Lee H, Schmidt CS, Hennessey JP Jr, French SW, Yeaman MR, Filler SG, Edwards JE Jr.

Vaccine. 2013 Nov 12;31(47):5549-56. doi: 10.1016/j.vaccine.2013.09.016. Epub 2013 Sep 21.

47.

Aspergillus galactosaminogalactan mediates adherence to host constituents and conceals hyphal β-glucan from the immune system.

Gravelat FN, Beauvais A, Liu H, Lee MJ, Snarr BD, Chen D, Xu W, Kravtsov I, Hoareau CM, Vanier G, Urb M, Campoli P, Al Abdallah Q, Lehoux M, Chabot JC, Ouimet MC, Baptista SD, Fritz JH, Nierman WC, Latgé JP, Mitchell AP, Filler SG, Fontaine T, Sheppard DC.

PLoS Pathog. 2013;9(8):e1003575. doi: 10.1371/journal.ppat.1003575. Epub 2013 Aug 22.

48.

Pharmacokinetics of posaconazole within epithelial cells and fungi: insights into potential mechanisms of action during treatment and prophylaxis.

Campoli P, Perlin DS, Kristof AS, White TC, Filler SG, Sheppard DC.

J Infect Dis. 2013 Nov 15;208(10):1717-28. doi: 10.1093/infdis/jit358. Epub 2013 Aug 1.

49.

Candida albicans CUG mistranslation is a mechanism to create cell surface variation.

Miranda I, Silva-Dias A, Rocha R, Teixeira-Santos R, Coelho C, Gonçalves T, Santos MA, Pina-Vaz C, Solis NV, Filler SG, Rodrigues AG.

MBio. 2013 Aug 30;4(4). pii: e00285-13. doi: 10.1128/mBio.00285-13.

50.

Can host receptors for fungi be targeted for treatment of fungal infections?

Filler SG.

Trends Microbiol. 2013 Aug;21(8):389-96. doi: 10.1016/j.tim.2013.05.006. Epub 2013 Jun 21. Review.

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