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Items: 11

1.

Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766).

Wigmore EM, Clarke TK, Howard DM, Adams MJ, Hall LS, Zeng Y, Gibson J, Davies G, Fernandez-Pujals AM, Thomson PA, Hayward C, Smith BH, Hocking LJ, Padmanabhan S, Deary IJ, Porteous DJ, Nicodemus KK, McIntosh AM.

Transl Psychiatry. 2017 Aug 15;7(8):e1205. doi: 10.1038/tp.2017.148.

2.

Assessing the presence of shared genetic architecture between Alzheimer's disease and major depressive disorder using genome-wide association data.

Gibson J, Russ TC, Adams MJ, Clarke TK, Howard DM, Hall LS, Fernandez-Pujals AM, Wigmore EM, Hayward C, Davies G, Murray AD, Smith BH, Porteous DJ, Deary IJ, McIntosh AM.

Transl Psychiatry. 2017 Apr 18;7(4):e1094. doi: 10.1038/tp.2017.49.

3.

Shared Genetics and Couple-Associated Environment Are Major Contributors to the Risk of Both Clinical and Self-Declared Depression.

Zeng Y, Navarro P, Xia C, Amador C, Fernandez-Pujals AM, Thomson PA, Campbell A, Nagy R, Clarke TK, Hafferty JD, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, MacIntyre DJ, Porteous DJ, Haley CS, McIntosh AM.

EBioMedicine. 2016 Dec;14:161-167. doi: 10.1016/j.ebiom.2016.11.003. Epub 2016 Nov 4.

4.

Dissection of major depressive disorder using polygenic risk scores for schizophrenia in two independent cohorts.

Whalley HC, Adams MJ, Hall LS, Clarke TK, Fernandez-Pujals AM, Gibson J, Wigmore E, Hafferty J, Hagenaars SP, Davies G, Campbell A, Hayward C, Lawrie SM, Porteous DJ, Deary IJ, McIntosh AM.

Transl Psychiatry. 2016 Nov 1;6(11):e938. doi: 10.1038/tp.2016.207.

5.

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis.

McIntosh AM, Hall LS, Zeng Y, Adams MJ, Gibson J, Wigmore E, Hagenaars SP, Davies G, Fernandez-Pujals AM, Campbell AI, Clarke TK, Hayward C, Haley CS, Porteous DJ, Deary IJ, Smith DJ, Nicholl BI, Hinds DA, Jones AV, Scollen S, Meng W, Smith BH, Hocking LJ.

PLoS Med. 2016 Aug 16;13(8):e1002090. doi: 10.1371/journal.pmed.1002090. eCollection 2016 Aug.

6.

A Combined Pathway and Regional Heritability Analysis Indicates NETRIN1 Pathway Is Associated With Major Depressive Disorder.

Zeng Y, Navarro P, Fernandez-Pujals AM, Hall LS, Clarke TK, Thomson PA, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, MacIntyre DJ, Wray NR; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Deary IJ, Porteous DJ, Haley CS, McIntosh AM.

Biol Psychiatry. 2017 Feb 15;81(4):336-346. doi: 10.1016/j.biopsych.2016.04.017. Epub 2016 May 2.

7.

Polygenic risk for coronary artery disease is associated with cognitive ability in older adults.

Hagenaars SP, Harris SE, Clarke TK, Hall L, Luciano M, Fernandez-Pujals AM, Davies G, Hayward C; Generation Scotland, Starr JM, Porteous DJ, McIntosh AM, Deary IJ.

Int J Epidemiol. 2016 Jan 28. pii: dyv354. [Epub ahead of print]

8.

Epidemiology and Heritability of Major Depressive Disorder, Stratified by Age of Onset, Sex, and Illness Course in Generation Scotland: Scottish Family Health Study (GS:SFHS).

Fernandez-Pujals AM, Adams MJ, Thomson P, McKechanie AG, Blackwood DH, Smith BH, Dominiczak AF, Morris AD, Matthews K, Campbell A, Linksted P, Haley CS, Deary IJ, Porteous DJ, MacIntyre DJ, McIntosh AM.

PLoS One. 2015 Nov 16;10(11):e0142197. doi: 10.1371/journal.pone.0142197. eCollection 2015.

9.

Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index.

Clarke TK, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Thomson P, Hayward C, Smith BH, Padmanabhan S, Hocking LJ, Deary IJ, Porteous DJ, McIntosh AM.

Transl Psychiatry. 2015 Jun 30;5:e592. doi: 10.1038/tp.2015.83.

10.

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort.

Clarke TK, Smith AH, Gelernter J, Kranzler HR, Farrer LA, Hall LS, Fernandez-Pujals AM, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Hayward C, Thomson PA, Porteous DJ, Deary IJ, McIntosh AM.

Addict Biol. 2016 Mar;21(2):469-80. doi: 10.1111/adb.12245. Epub 2015 Apr 10.

11.

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population.

Clarke TK, Lupton MK, Fernandez-Pujals AM, Starr J, Davies G, Cox S, Pattie A, Liewald DC, Hall LS, MacIntyre DJ, Smith BH, Hocking LJ, Padmanabhan S, Thomson PA, Hayward C, Hansell NK, Montgomery GW, Medland SE, Martin NG, Wright MJ, Porteous DJ, Deary IJ, McIntosh AM.

Mol Psychiatry. 2016 Mar;21(3):419-25. doi: 10.1038/mp.2015.12. Epub 2015 Mar 10.

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