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Items: 14

1.

Off and back-on again: a tumor suppressor's tale.

Acosta J, Wang W, Feldser DM.

Oncogene. 2018 Mar 15. doi: 10.1038/s41388-018-0186-3. [Epub ahead of print] Review.

PMID:
29540833
2.

Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression.

Cicchini M, Buza EL, Sagal KM, Gudiel AA, Durham AC, Feldser DM.

Cell Rep. 2017 Feb 21;18(8):1958-1969. doi: 10.1016/j.celrep.2017.01.069.

3.

Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.

Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM.

Cancer Res. 2017 Apr 1;77(7):1719-1729. doi: 10.1158/0008-5472.CAN-16-2159. Epub 2017 Feb 15.

4.

Recombinase-based conditional and reversible gene regulation via XTR alleles.

Robles-Oteiza C, Taylor S, Yates T, Cicchini M, Lauderback B, Cashman CR, Burds AA, Winslow MM, Jacks T, Feldser DM.

Nat Commun. 2015 Nov 5;6:8783. doi: 10.1038/ncomms9783.

5.

A conditional system to specifically link disruption of protein-coding function with reporter expression in mice.

Chiou SH, Kim-Kiselak C, Risca VI, Heimann MK, Chuang CH, Burds AA, Greenleaf WJ, Jacks TE, Feldser DM, Winslow MM.

Cell Rep. 2014 Jun 26;7(6):2078-86. doi: 10.1016/j.celrep.2014.05.031. Epub 2014 Jun 12.

6.

Response and resistance to NF-κB inhibitors in mouse models of lung adenocarcinoma.

Xue W, Meylan E, Oliver TG, Feldser DM, Winslow MM, Bronson R, Jacks T.

Cancer Discov. 2011 Aug;1(3):236-47. doi: 10.1158/2159-8290.CD-11-0073. Epub 2011 Jun 16.

7.

Suppression of lung adenocarcinoma progression by Nkx2-1.

Winslow MM, Dayton TL, Verhaak RG, Kim-Kiselak C, Snyder EL, Feldser DM, Hubbard DD, DuPage MJ, Whittaker CA, Hoersch S, Yoon S, Crowley D, Bronson RT, Chiang DY, Meyerson M, Jacks T.

Nature. 2011 May 5;473(7345):101-4. doi: 10.1038/nature09881. Epub 2011 Apr 6.

8.

Stage-specific sensitivity to p53 restoration during lung cancer progression.

Feldser DM, Kostova KK, Winslow MM, Taylor SE, Cashman C, Whittaker CA, Sanchez-Rivera FJ, Resnick R, Bronson R, Hemann MT, Jacks T.

Nature. 2010 Nov 25;468(7323):572-5. doi: 10.1038/nature09535.

9.

Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma.

Meylan E, Dooley AL, Feldser DM, Shen L, Turk E, Ouyang C, Jacks T.

Nature. 2009 Nov 5;462(7269):104-7. doi: 10.1038/nature08462. Epub 2009 Oct 21.

10.

Short telomeres limit tumor progression in vivo by inducing senescence.

Feldser DM, Greider CW.

Cancer Cell. 2007 May;11(5):461-9. Epub 2007 Apr 12.

11.

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.

Hao LY, Armanios M, Strong MA, Karim B, Feldser DM, Huso D, Greider CW.

Cell. 2005 Dec 16;123(6):1121-31.

12.

Telomere dysfunction and the initiation of genome instability.

Feldser DM, Hackett JA, Greider CW.

Nat Rev Cancer. 2003 Aug;3(8):623-7. doi: 10.1038/nrc1142.

PMID:
12894250
14.

Telomere dysfunction increases mutation rate and genomic instability.

Hackett JA, Feldser DM, Greider CW.

Cell. 2001 Aug 10;106(3):275-86.

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