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Items: 46

1.

Commonly Occurring Cell Subsets in High-Grade Serous Ovarian Tumors Identified by Single-Cell Mass Cytometry.

Gonzalez VD, Samusik N, Chen TJ, Savig ES, Aghaeepour N, Quigley DA, Huang YW, Giangarrà V, Borowsky AD, Hubbard NE, Chen SY, Han G, Ashworth A, Kipps TJ, Berek JS, Nolan GP, Fantl WJ.

Cell Rep. 2018 Feb 13;22(7):1875-1888. doi: 10.1016/j.celrep.2018.01.053.

2.

Atomic mass tag of bismuth-209 for increasing the immunoassay multiplexing capacity of mass cytometry.

Han G, Chen SY, Gonzalez VD, Zunder ER, Fantl WJ, Nolan GP.

Cytometry A. 2017 Dec;91(12):1150-1163. doi: 10.1002/cyto.a.23283. Epub 2017 Dec 4.

3.

Upregulation of Human Endogenous Retrovirus-K Is Linked to Immunity and Inflammation in Pulmonary Arterial Hypertension.

Saito T, Miyagawa K, Chen SY, Tamosiuniene R, Wang L, Sharpe O, Samayoa E, Harada D, Moonen JAJ, Cao A, Chen PI, Hennigs JK, Gu M, Li CG, Leib RD, Li D, Adams CM, Del Rosario PA, Bill M, Haddad F, Montoya JG, Robinson WH, Fantl WJ, Nolan GP, Zamanian RT, Nicolls MR, Chiu CY, Ariza ME, Rabinovitch M.

Circulation. 2017 Nov 14;136(20):1920-1935. doi: 10.1161/CIRCULATIONAHA.117.027589. Epub 2017 Sep 21.

PMID:
28935667
4.

High-resolution myogenic lineage mapping by single-cell mass cytometry.

Porpiglia E, Samusik N, Van Ho AT, Cosgrove BD, Mai T, Davis KL, Jager A, Nolan GP, Bendall SC, Fantl WJ, Blau HM.

Nat Cell Biol. 2017 May;19(5):558-567. doi: 10.1038/ncb3507. Epub 2017 Apr 17.

5.

High-throughput precision measurement of subcellular localization in single cells.

Burns TJ, Frei AP, Gherardini PF, Bava FA, Batchelder JE, Yoshiyasu Y, Yu JM, Groziak AR, Kimmey SC, Gonzalez VD, Fantl WJ, Nolan GP.

Cytometry A. 2017 Feb;91(2):180-189. doi: 10.1002/cyto.a.23054. Epub 2017 Jan 17.

6.

IMMUNOLOGY. An interactive reference framework for modeling a dynamic immune system.

Spitzer MH, Gherardini PF, Fragiadakis GK, Bhattacharya N, Yuan RT, Hotson AN, Finck R, Carmi Y, Zunder ER, Fantl WJ, Bendall SC, Engleman EG, Nolan GP.

Science. 2015 Jul 10;349(6244):1259425. doi: 10.1126/science.1259425.

7.

Mass Cytometric Functional Profiling of Acute Myeloid Leukemia Defines Cell-Cycle and Immunophenotypic Properties That Correlate with Known Responses to Therapy.

Behbehani GK, Samusik N, Bjornson ZB, Fantl WJ, Medeiros BC, Nolan GP.

Cancer Discov. 2015 Sep;5(9):988-1003. doi: 10.1158/2159-8290.CD-15-0298. Epub 2015 Jun 19.

8.

Single-cell systems-level analysis of human Toll-like receptor activation defines a chemokine signature in patients with systemic lupus erythematosus.

O'Gorman WE, Hsieh EW, Savig ES, Gherardini PF, Hernandez JD, Hansmann L, Balboni IM, Utz PJ, Bendall SC, Fantl WJ, Lewis DB, Nolan GP, Davis MM.

J Allergy Clin Immunol. 2015 Nov;136(5):1326-36. doi: 10.1016/j.jaci.2015.04.008. Epub 2015 May 30.

9.

Palladium-based mass tag cell barcoding with a doublet-filtering scheme and single-cell deconvolution algorithm.

Zunder ER, Finck R, Behbehani GK, Amir el-AD, Krishnaswamy S, Gonzalez VD, Lorang CG, Bjornson Z, Spitzer MH, Bodenmiller B, Fantl WJ, Pe'er D, Nolan GP.

Nat Protoc. 2015 Feb;10(2):316-33. doi: 10.1038/nprot.2015.020. Epub 2015 Jan 22.

10.

Transient partial permeabilization with saponin enables cellular barcoding prior to surface marker staining.

Behbehani GK, Thom C, Zunder ER, Finck R, Gaudilliere B, Fragiadakis GK, Fantl WJ, Nolan GP.

Cytometry A. 2014 Dec;85(12):1011-9. doi: 10.1002/cyto.a.22573. Epub 2014 Oct 1.

11.

Clinical recovery from surgery correlates with single-cell immune signatures.

Gaudillière B, Fragiadakis GK, Bruggner RV, Nicolau M, Finck R, Tingle M, Silva J, Ganio EA, Yeh CG, Maloney WJ, Huddleston JI, Goodman SB, Davis MM, Bendall SC, Fantl WJ, Angst MS, Nolan GP.

Sci Transl Med. 2014 Sep 24;6(255):255ra131. doi: 10.1126/scitranslmed.3009701.

12.

Single-cell mass cytometry for analysis of immune system functional states.

Bjornson ZB, Nolan GP, Fantl WJ.

Curr Opin Immunol. 2013 Aug;25(4):484-94. doi: 10.1016/j.coi.2013.07.004. Epub 2013 Aug 31. Review.

13.

Single-cell mass cytometry adapted to measurements of the cell cycle.

Behbehani GK, Bendall SC, Clutter MR, Fantl WJ, Nolan GP.

Cytometry A. 2012 Jul;81(7):552-66. doi: 10.1002/cyto.a.22075. Epub 2012 Jun 12.

14.

A platinum-based covalent viability reagent for single-cell mass cytometry.

Fienberg HG, Simonds EF, Fantl WJ, Nolan GP, Bodenmiller B.

Cytometry A. 2012 Jun;81(6):467-75. doi: 10.1002/cyto.a.22067. Epub 2012 May 10.

15.

Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.

Palazzo AL, Evensen E, Huang YW, Cesano A, Nolan GP, Fantl WJ.

PLoS One. 2011;6(10):e24592. doi: 10.1371/journal.pone.0024592. Epub 2011 Oct 10.

16.

Signaling changes in the stem cell factor-AKT-S6 pathway in diagnostic AML samples are associated with disease relapse.

Kornblau SM, Covey T, Putta S, Cohen A, Woronicz J, Fantl WJ, Gayko U, Cesano A.

Blood Cancer J. 2011 Feb;1(2):e3. doi: 10.1038/bcj.2010.2. Epub 2011 Feb 11. No abstract available.

17.

Functional characterization of FLT3 receptor signaling deregulation in acute myeloid leukemia by single cell network profiling (SCNP).

Rosen DB, Minden MD, Kornblau SM, Cohen A, Gayko U, Putta S, Woronicz J, Evensen E, Fantl WJ, Cesano A.

PLoS One. 2010 Oct 27;5(10):e13543. doi: 10.1371/journal.pone.0013543.

18.

Distinct patterns of DNA damage response and apoptosis correlate with Jak/Stat and PI3kinase response profiles in human acute myelogenous leukemia.

Rosen DB, Putta S, Covey T, Huang YW, Nolan GP, Cesano A, Minden MD, Fantl WJ.

PLoS One. 2010 Aug 25;5(8):e12405. doi: 10.1371/journal.pone.0012405.

19.

Dynamic single-cell network profiles in acute myelogenous leukemia are associated with patient response to standard induction therapy.

Kornblau SM, Minden MD, Rosen DB, Putta S, Cohen A, Covey T, Spellmeyer DC, Fantl WJ, Gayko U, Cesano A.

Clin Cancer Res. 2010 Jul 15;16(14):3721-33. doi: 10.1158/1078-0432.CCR-10-0093. Epub 2010 Jun 4.

20.

beta-Catenin regulates vascular endothelial growth factor expression in colon cancer.

Easwaran V, Lee SH, Inge L, Guo L, Goldbeck C, Garrett E, Wiesmann M, Garcia PD, Fuller JH, Chan V, Randazzo F, Gundel R, Warren RS, Escobedo J, Aukerman SL, Taylor RN, Fantl WJ.

Cancer Res. 2003 Jun 15;63(12):3145-53.

21.

c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs.

Stein M, Bagnoli F, Halenbeck R, Rappuoli R, Fantl WJ, Covacci A.

Mol Microbiol. 2002 Feb;43(4):971-80.

22.

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors.

Yan D, Wiesmann M, Rohan M, Chan V, Jefferson AB, Guo L, Sakamoto D, Caothien RH, Fuller JH, Reinhard C, Garcia PD, Randazzo FM, Escobedo J, Fantl WJ, Williams LT.

Proc Natl Acad Sci U S A. 2001 Dec 18;98(26):14973-8.

23.

PAR-1 is a Dishevelled-associated kinase and a positive regulator of Wnt signalling.

Sun TQ, Lu B, Feng JJ, Reinhard C, Jan YN, Fantl WJ, Williams LT.

Nat Cell Biol. 2001 Jul;3(7):628-36.

PMID:
11433294
24.

Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian Nkd.

Yan D, Wallingford JB, Sun TQ, Nelson AM, Sakanaka C, Reinhard C, Harland RM, Fantl WJ, Williams LT.

Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3802-7.

25.

Regulation of cyclooxygenase-2 and periostin by Wnt-3 in mouse mammary epithelial cells.

Haertel-Wiesmann M, Liang Y, Fantl WJ, Williams LT.

J Biol Chem. 2000 Oct 13;275(41):32046-51.

26.

16K human prolactin inhibits vascular endothelial growth factor-induced activation of Ras in capillary endothelial cells.

D'Angelo G, Martini JF, Iiri T, Fantl WJ, Martial J, Weiner RI.

Mol Endocrinol. 1999 May;13(5):692-704.

PMID:
10319320
27.

Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK.

Yu W, Fantl WJ, Harrowe G, Williams LT.

Curr Biol. 1998 Jan 1;8(1):56-64.

28.

Reduction of food intake and weight gain by the ob protein requires a specific secondary structure and is reversible.

Giese K, Fantl WJ, Vitt C, Stephans JC, Cousens L, Wachowicz M, Williams LT.

Mol Med. 1996 Jan;2(1):50-8.

29.

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.

Hu Q, Klippel A, Muslin AJ, Fantl WJ, Williams LT.

Science. 1995 Apr 7;268(5207):100-2.

PMID:
7701328
30.

Activation of Na+/H+ exchange by platelet-derived growth factor involves phosphatidylinositol 3'-kinase and phospholipase C gamma.

Ma YH, Reusch HP, Wilson E, Escobedo JA, Fantl WJ, Williams LT, Ives HE.

J Biol Chem. 1994 Dec 2;269(48):30734-9.

31.

Activation of Raf-1 by 14-3-3 proteins.

Fantl WJ, Muslin AJ, Kikuchi A, Martin JA, MacNicol AM, Gross RW, Williams LT.

Nature. 1994 Oct 13;371(6498):612-4.

PMID:
7935795
32.

HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization.

Baur AS, Sawai ET, Dazin P, Fantl WJ, Cheng-Mayer C, Peterlin BM.

Immunity. 1994 Aug;1(5):373-84.

PMID:
7882168
33.
34.

Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.

Satoh T, Fantl WJ, Escobedo JA, Williams LT, Kaziro Y.

Mol Cell Biol. 1993 Jun;13(6):3706-13.

35.

Signalling by receptor tyrosine kinases.

Fantl WJ, Johnson DE, Williams LT.

Annu Rev Biochem. 1993;62:453-81. Review. No abstract available.

PMID:
7688944
36.

Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways.

Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT.

Cell. 1992 May 1;69(3):413-23.

PMID:
1374684
38.

Interactions of PDGF and FGF receptors with cytoplasmic signaling molecules.

Peters KG, Escobedo JA, Fantl WJ, Williams LT.

Cold Spring Harb Symp Quant Biol. 1992;57:63-6. Review. No abstract available.

PMID:
1339700
39.

Interactions of growth factor receptors with cytoplasmic signaling molecules.

Williams LT, Escobedo JA, Fantl WJ, Turck CW, Klippel A.

Cold Spring Harb Symp Quant Biol. 1991;56:243-50. Review.

PMID:
1668083
40.
42.

Ligand activation causes a phosphorylation-dependent change in platelet-derived growth factor receptor conformation.

Keating MT, Escobedo JA, Fantl WJ, Williams LT.

Trans Assoc Am Physicians. 1988;101:24-32.

PMID:
2480016
44.

Properties of carboxymethylated cross-linked hemoglobin A.

Fantl WJ, Manning LR, Ueno H, Di Donato A, Manning JM.

Biochemistry. 1987 Sep 8;26(18):5755-61.

PMID:
3676286
45.

Selective carboxymethylation of the alpha-amino groups of hemoglobin. Effect on functional properties.

DiDonato A, Fantl WJ, Acharya AS, Manning JM.

J Biol Chem. 1983 Oct 10;258(19):11890-5.

46.

Acetaldehyde adducts with hemoglobin.

Stevens VJ, Fantl WJ, Newman CB, Sims RV, Cerami A, Peterson CM.

J Clin Invest. 1981 Feb;67(2):361-9.

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