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Oncogenic dependency on β-catenin in liver cancer cell lines correlates with pathway activation.

Ding Z, Shi C, Jiang L, Tolstykh T, Cao H, Bangari DS, Ryan S, Levit M, Jin T, Mamaat K, Yu Q, Qu H, Hopke J, Cindhuchao M, Hoffmann D, Sun F, Helms MW, Jahn-Hofmann K, Scheidler S, Schweizer L, Fang DD, Pollard J, Winter C, Wiederschain D.

Oncotarget. 2017 Sep 28;8(70):114526-114539. doi: 10.18632/oncotarget.21298. eCollection 2017 Dec 29.


Genome-wide analysis of gene expression of EMS-induced short fiber mutant Ligon lintless-y (liy) in cotton (Gossypium hirsutum L.).

Naoumkina M, Bechere E, Fang DD, Thyssen GN, Florane CB.

Genomics. 2017 Jul;109(3-4):320-329. doi: 10.1016/j.ygeno.2017.05.007. Epub 2017 May 31.


Role of xyloglucan in cotton (Gossypium hirsutum L.) fiber elongation of the short fiber mutant Ligon lintless-2 (Li2).

Naoumkina M, Hinchliffe DJ, Fang DD, Florane CB, Thyssen GN.

Gene. 2017 Aug 30;626:227-233. doi: 10.1016/j.gene.2017.05.042. Epub 2017 May 22.


Genomic insights into divergence and dual domestication of cultivated allotetraploid cottons.

Fang L, Gong H, Hu Y, Liu C, Zhou B, Huang T, Wang Y, Chen S, Fang DD, Du X, Chen H, Chen J, Wang S, Wang Q, Wan Q, Liu B, Pan M, Chang L, Wu H, Mei G, Xiang D, Li X, Cai C, Zhu X, Chen ZJ, Han B, Chen X, Guo W, Zhang T, Huang X.

Genome Biol. 2017 Feb 20;18(1):33. doi: 10.1186/s13059-017-1167-5.


Diversity analysis of cotton (Gossypium hirsutum L.) germplasm using the CottonSNP63K Array.

Hinze LL, Hulse-Kemp AM, Wilson IW, Zhu QH, Llewellyn DJ, Taylor JM, Spriggs A, Fang DD, Ulloa M, Burke JJ, Giband M, Lacape JM, Van Deynze A, Udall JA, Scheffler JA, Hague S, Wendel JF, Pepper AE, Frelichowski J, Lawley CT, Jones DC, Percy RG, Stelly DM.

BMC Plant Biol. 2017 Feb 3;17(1):37. doi: 10.1186/s12870-017-0981-y.


A Gly65Val substitution in an actin, GhACT_LI1, disrupts cell polarity and F-actin organization resulting in dwarf, lintless cotton plants.

Thyssen GN, Fang DD, Turley RB, Florane CB, Li P, Mattison CP, Naoumkina M.

Plant J. 2017 Apr;90(1):111-121. doi: 10.1111/tpj.13477. Epub 2017 Mar 6.


A MAGIC population-based genome-wide association study reveals functional association of GhRBB1_A07 gene with superior fiber quality in cotton.

Islam MS, Thyssen GN, Jenkins JN, Zeng L, Delhom CD, McCarty JC, Deng DD, Hinchliffe DJ, Jones DC, Fang DD.

BMC Genomics. 2016 Nov 9;17(1):903.


The GhTT2_A07 gene is linked to the brown colour and natural flame retardancy phenotypes of Lc1 cotton (Gossypium hirsutum L.) fibres.

Hinchliffe DJ, Condon BD, Thyssen G, Naoumkina M, Madison CA, Reynolds M, Delhom CD, Fang DD, Li P, McCarty J.

J Exp Bot. 2016 Oct;67(18):5461-5471. Epub 2016 Aug 27.


The Immature Fiber Mutant Phenotype of Cotton (Gossypium hirsutum) Is Linked to a 22-bp Frame-Shift Deletion in a Mitochondria Targeted Pentatricopeptide Repeat Gene.

Thyssen GN, Fang DD, Zeng L, Song X, Delhom CD, Condon TL, Li P, Kim HJ.

G3 (Bethesda). 2016 Jun 1;6(6):1627-33. doi: 10.1534/g3.116.027649.


Mapping by sequencing in cotton (Gossypium hirsutum) line MD52ne identified candidate genes for fiber strength and its related quality attributes.

Islam MS, Zeng L, Thyssen GN, Delhom CD, Kim HJ, Li P, Fang DD.

Theor Appl Genet. 2016 Jun;129(6):1071-86. doi: 10.1007/s00122-016-2684-4. Epub 2016 Feb 16.


Comparative fiber property and transcriptome analyses reveal key genes potentially related to high fiber strength in cotton (Gossypium hirsutum L.) line MD52ne.

Islam MS, Fang DD, Thyssen GN, Delhom CD, Liu Y, Kim HJ.

BMC Plant Biol. 2016 Feb 1;16:36. doi: 10.1186/s12870-016-0727-2.


Genetic Diversity of the Two Commercial Tetraploid Cotton Species in the Gossypium Diversity Reference Set.

Hinze LL, Gazave E, Gore MA, Fang DD, Scheffler BE, Yu JZ, Jones DC, Frelichowski J, Percy RG.

J Hered. 2016 May;107(3):274-86. doi: 10.1093/jhered/esw004. Epub 2016 Jan 16. Erratum in: J Hered. 2016 Sep;107(5):478.


Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma.

Yang S, Luo C, Gu Q, Xu Q, Wang G, Sun H, Qian Z, Tan Y, Qin Y, Shen Y, Xu X, Chen SH, Chan CC, Wang H, Mao M, Fang DD.

Oncotarget. 2016 Feb 2;7(5):5461-9. doi: 10.18632/oncotarget.6684.


Genomic characterization of a large panel of patient-derived hepatocellular carcinoma xenograft tumor models for preclinical development.

Gu Q, Zhang B, Sun H, Xu Q, Tan Y, Wang G, Luo Q, Xu W, Yang S, Li J, Fu J, Chen L, Yuan S, Liang G, Ji Q, Chen SH, Chan CC, Zhou W, Xu X, Wang H, Fang DD.

Oncotarget. 2015 Aug 21;6(24):20160-76.


Mapping-by-sequencing of Ligon-lintless-1 (Li 1 ) reveals a cluster of neighboring genes with correlated expression in developing fibers of Upland cotton (Gossypium hirsutum L.).

Thyssen GN, Fang DD, Turley RB, Florane C, Li P, Naoumkina M.

Theor Appl Genet. 2015 Sep;128(9):1703-12. doi: 10.1007/s00122-015-2539-4. Epub 2015 May 29.


Phytohormonal networks promote differentiation of fiber initials on pre-anthesis cotton ovules grown in vitro and in planta.

Kim HJ, Hinchliffe DJ, Triplett BA, Chen ZJ, Stelly DM, Yeater KM, Moon HS, Gilbert MK, Thyssen GN, Turley RB, Fang DD.

PLoS One. 2015 Apr 30;10(4):e0125046. doi: 10.1371/journal.pone.0125046. eCollection 2015.


Development of a 63K SNP Array for Cotton and High-Density Mapping of Intraspecific and Interspecific Populations of Gossypium spp.

Hulse-Kemp AM, Lemm J, Plieske J, Ashrafi H, Buyyarapu R, Fang DD, Frelichowski J, Giband M, Hague S, Hinze LL, Kochan KJ, Riggs PK, Scheffler JA, Udall JA, Ulloa M, Wang SS, Zhu QH, Bag SK, Bhardwaj A, Burke JJ, Byers RL, Claverie M, Gore MA, Harker DB, Islam MS, Jenkins JN, Jones DC, Lacape JM, Llewellyn DJ, Percy RG, Pepper AE, Poland JA, Mohan Rai K, Sawant SV, Singh SK, Spriggs A, Taylor JM, Wang F, Yourstone SM, Zheng X, Lawley CT, Ganal MW, Van Deynze A, Wilson IW, Stelly DM.

G3 (Bethesda). 2015 Apr 22;5(6):1187-209. doi: 10.1534/g3.115.018416.


BAC-End Sequence-Based SNP Mining in Allotetraploid Cotton (Gossypium) Utilizing Resequencing Data, Phylogenetic Inferences, and Perspectives for Genetic Mapping.

Hulse-Kemp AM, Ashrafi H, Stoffel K, Zheng X, Saski CA, Scheffler BE, Fang DD, Chen ZJ, Van Deynze A, Stelly DM.

G3 (Bethesda). 2015 Apr 9;5(6):1095-105. doi: 10.1534/g3.115.017749.


Serum 25-hydroxyvitamin D levels and peripheral neuropathy in patients with type 2 diabetes: a systematic review and meta-analysis.

Lv WS, Zhao WJ, Gong SL, Fang DD, Wang B, Fu ZJ, Yan SL, Wang YG.

J Endocrinol Invest. 2015 May;38(5):513-8. doi: 10.1007/s40618-014-0210-6. Epub 2014 Dec 21. Review.


A comparative meta-analysis of QTL between intraspecific Gossypium hirsutum and interspecific G. hirsutum × G. barbadense populations.

Said JI, Song M, Wang H, Lin Z, Zhang X, Fang DD, Zhang J.

Mol Genet Genomics. 2015 Jun;290(3):1003-25. doi: 10.1007/s00438-014-0963-9. Epub 2014 Dec 12.


Development of EST-based SNP and InDel markers and their utilization in tetraploid cotton genetic mapping.

Li X, Gao W, Guo H, Zhang X, Fang DD, Lin Z.

BMC Genomics. 2014 Dec 1;15:1046. doi: 10.1186/1471-2164-15-1046.


Molecular characterization of the Gossypium Diversity Reference Set of the US National Cotton Germplasm Collection.

Hinze LL, Fang DD, Gore MA, Scheffler BE, Yu JZ, Frelichowski J, Percy RG.

Theor Appl Genet. 2015 Feb;128(2):313-27. doi: 10.1007/s00122-014-2431-7. Epub 2014 Nov 28.


Mapping genomic loci for cotton plant architecture, yield components, and fiber properties in an interspecific (Gossypium hirsutum L. × G. barbadense L.) RIL population.

Yu JZ, Ulloa M, Hoffman SM, Kohel RJ, Pepper AE, Fang DD, Percy RG, Burke JJ.

Mol Genet Genomics. 2014 Dec;289(6):1347-67. doi: 10.1007/s00438-014-0930-5. Epub 2014 Oct 15.


Next generation genetic mapping of the Ligon-lintless-2 (Li₂) locus in upland cotton (Gossypium hirsutum L.).

Thyssen GN, Fang DD, Turley RB, Florane C, Li P, Naoumkina M.

Theor Appl Genet. 2014 Oct;127(10):2183-92. doi: 10.1007/s00122-014-2372-1. Epub 2014 Aug 15.


Quantitative trait loci analysis of fiber quality traits using a random-mated recombinant inbred population in Upland cotton (Gossypium hirsutum L.).

Fang DD, Jenkins JN, Deng DD, McCarty JC, Li P, Wu J.

BMC Genomics. 2014 May 24;15:397. doi: 10.1186/1471-2164-15-397.


Independent replication of mitochondrial genes supports the transcriptional program in developing fiber cells of cotton (Gossypium hirsutum L.).

Thyssen GN, Song X, Naoumkina M, Kim HJ, Fang DD.

Gene. 2014 Jul 1;544(1):41-8. doi: 10.1016/j.gene.2014.04.038. Epub 2014 Apr 22.


Comparative transcriptome analysis of short fiber mutants Ligon-lintless 1 and 2 reveals common mechanisms pertinent to fiber elongation in cotton (Gossypium hirsutum L.).

Gilbert MK, Kim HJ, Tang Y, Naoumkina M, Fang DD.

PLoS One. 2014 Apr 18;9(4):e95554. doi: 10.1371/journal.pone.0095554. eCollection 2014.


The Li2 mutation results in reduced subgenome expression bias in elongating fibers of allotetraploid cotton (Gossypium hirsutum L.).

Naoumkina M, Thyssen G, Fang DD, Hinchliffe DJ, Florane C, Yeater KM, Page JT, Udall JA.

PLoS One. 2014 Mar 5;9(3):e90830. doi: 10.1371/journal.pone.0090830. eCollection 2014.


HIP1-ALK, a novel ALK fusion variant that responds to crizotinib.

Fang DD, Zhang B, Gu Q, Lira M, Xu Q, Sun H, Qian M, Sheng W, Ozeck M, Wang Z, Zhang C, Chen X, Chen KX, Li J, Chen SH, Christensen J, Mao M, Chan CC.

J Thorac Oncol. 2014 Mar;9(3):285-94. doi: 10.1097/JTO.0000000000000087.


A transcript profiling approach reveals an abscisic acid-specific glycosyltransferase (UGT73C14) induced in developing fiber of Ligon lintless-2 mutant of cotton (Gossypium hirsutum L.).

Gilbert MK, Bland JM, Shockey JM, Cao H, Hinchliffe DJ, Fang DD, Naoumkina M.

PLoS One. 2013 Sep 23;8(9):e75268. doi: 10.1371/journal.pone.0075268. eCollection 2013.


Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.

Fang DD, Zhang CC, Gu Y, Jani JP, Cao J, Tsaparikos K, Yuan J, Thiel M, Jackson-Fisher A, Zong Q, Lappin PB, Hayashi T, Schwab RB, Wong A, John-Baptiste A, Bagrodia S, Los G, Bender S, Christensen J, Vanarsdale T.

PLoS One. 2013 Jun 27;8(6):e67258. doi: 10.1371/journal.pone.0067258. Print 2013.


Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line.

Fang DD, Cao J, Jani JP, Tsaparikos K, Blasina A, Kornmann J, Lira ME, Wang J, Jirout Z, Bingham J, Zhu Z, Gu Y, Los G, Hostomsky Z, Vanarsdale T.

Front Med. 2013 Dec;7(4):462-76. doi: 10.1007/s11684-013-0270-6. Epub 2013 Jul 2.


Transcript profiling by microarray and marker analysis of the short cotton (Gossypium hirsutum L.) fiber mutant Ligon lintless-1 (Li1).

Gilbert MK, Turley RB, Kim HJ, Li P, Thyssen G, Tang Y, Delhom CD, Naoumkina M, Fang DD.

BMC Genomics. 2013 Jun 17;14:403. doi: 10.1186/1471-2164-14-403.


Integrated metabolomics and genomics analysis provides new insights into the fiber elongation process in Ligon lintless-2 mutant cotton (Gossypium hirsutum L.).

Naoumkina M, Hinchliffe DJ, Turley RB, Bland JM, Fang DD.

BMC Genomics. 2013 Mar 7;14:155. doi: 10.1186/1471-2164-14-155.


Synergistic effect of the γ-secretase inhibitor PF-03084014 and docetaxel in breast cancer models.

Zhang CC, Yan Z, Zong Q, Fang DD, Painter C, Zhang Q, Chen E, Lira ME, John-Baptiste A, Christensen JG.

Stem Cells Transl Med. 2013 Mar;2(3):233-42. doi: 10.5966/sctm.2012-0096. Epub 2013 Feb 13.


A high density consensus genetic map of tetraploid cotton that integrates multiple component maps through molecular marker redundancy check.

Blenda A, Fang DD, Rami JF, Garsmeur O, Luo F, Lacape JM.

PLoS One. 2012;7(9):e45739. doi: 10.1371/journal.pone.0045739. Epub 2012 Sep 24. Erratum in: PLoS One. 2013;8(3). doi:10.1371/annotation/ab8211a0-53a5-4765-a7cb-4b613ffb1b09.


Molecular markers associated with the immature fiber (im) gene affecting the degree of fiber cell wall thickening in cotton (Gossypium hirsutum L.).

Kim HJ, Moon HS, Delhom CD, Zeng L, Fang DD.

Theor Appl Genet. 2013 Jan;126(1):23-31. doi: 10.1007/s00122-012-1956-x. Epub 2012 Aug 14.


Cloning and expression analysis of novel Aux/IAA family genes in Gossypium hirsutum.

Han X, Xu X, Fang DD, Zhang T, Guo W.

Gene. 2012 Jul 15;503(1):83-91. doi: 10.1016/j.gene.2012.03.069. Epub 2012 Apr 2.


Identification of cancer stem cells provides novel tumor models for drug discovery.

Fang DD, Wen D, Xu Y.

Front Med. 2012 Jun;6(2):112-21. doi: 10.1007/s11684-012-0199-1. Epub 2012 May 9. Review.


A high-density simple sequence repeat and single nucleotide polymorphism genetic map of the tetraploid cotton genome.

Yu JZ, Kohel RJ, Fang DD, Cho J, Van Deynze A, Ulloa M, Hoffman SM, Pepper AE, Stelly DM, Jenkins JN, Saha S, Kumpatla SP, Shah MR, Hugie WV, Percy RG.

G3 (Bethesda). 2012 Jan;2(1):43-58. doi: 10.1534/g3.111.001552. Epub 2012 Jan 1.


Cloning and characterization of homeologous cellulose synthase catalytic subunit 2 genes from allotetraploid cotton (Gossypium hirsutum L.).

Kim HJ, Triplett BA, Zhang HB, Lee MK, Hinchliffe DJ, Li P, Fang DD.

Gene. 2012 Feb 25;494(2):181-9. doi: 10.1016/j.gene.2011.12.018. Epub 2011 Dec 20.


A combined functional and structural genomics approach identified an EST-SSR marker with complete linkage to the Ligon lintless-2 genetic locus in cotton (Gossypium hirsutum L.).

Hinchliffe DJ, Turley RB, Naoumkina M, Kim HJ, Tang Y, Yeater KM, Li P, Fang DD.

BMC Genomics. 2011 Sep 9;12:445. doi: 10.1186/1471-2164-12-445.


Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis.

Bard-Chapeau EA, Li S, Ding J, Zhang SS, Zhu HH, Princen F, Fang DD, Han T, Bailly-Maitre B, Poli V, Varki NM, Wang H, Feng GS.

Cancer Cell. 2011 May 17;19(5):629-39. doi: 10.1016/j.ccr.2011.03.023.


Functional analysis of Gossypium hirsutum cellulose synthase catalytic subunit 4 promoter in transgenic Arabidopsis and cotton tissues.

Kim HJ, Murai N, Fang DD, Triplett BA.

Plant Sci. 2011 Feb;180(2):323-32. doi: 10.1016/j.plantsci.2010.10.003. Epub 2010 Oct 12.


Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery.

Fang DD, Kim YJ, Lee CN, Aggarwal S, McKinnon K, Mesmer D, Norton J, Birse CE, He T, Ruben SM, Moore PA.

Br J Cancer. 2010 Apr 13;102(8):1265-75. doi: 10.1038/sj.bjc.6605610. Epub 2010 Mar 23.


A new SNP haplotype associated with blue disease resistance gene in cotton (Gossypium hirsutum L.).

Fang DD, Xiao J, Canci PC, Cantrell RG.

Theor Appl Genet. 2010 Mar;120(5):943-53. doi: 10.1007/s00122-009-1223-y. Epub 2009 Dec 4.


Identification and genomic location of a reniform nematode (Rotylenchulus reniformis) resistance locus (Ren ari) introgressed from Gossypium aridum into upland cotton (G. hirsutum).

Romano GB, Sacks EJ, Stetina SR, Robinson AF, Fang DD, Gutierrez OA, Scheffler JA.

Theor Appl Genet. 2009 Dec;120(1):139-50. doi: 10.1007/s00122-009-1165-4. Epub 2009 Oct 14.

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